“…SIMPLE SUMMARY: This prospective phase II–III randomized trial explores the value of modern technology for prudent radiation dose escalation in the curative management of patients with rectal cancer. …”
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“…Early detection of the tumor and its metastasis is essential, as the rate of disease recurrence is high and occurs in 27% to 53% of all patients who underwent curative therapy with radical prostatectomy or local radiotherapy. …”
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“…BACKGROUND: The HIV-1 reservoir is a major barrier to curative strategies. Inflammation is an important factor for HIV-1 reservoir persistence. …”
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“…Current chemotherapeutic treatment options rely on benzimidazoles, which have limited curative capabilities and can cause severe side effects. …”
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“…OBJECTIVE: To investigate the efficacy and safety of humanized CD19-specific chimeric antigen receptor T cells（hCART19s）in treating children and young adults with relapsed/refractory acute lymphoblastic leukemia（R/R ALL）and to analyze relevant factors affecting its curative effect and prognosis. METHODS: We conducted a single-center clinical trial involving 31 children and young adult patients with R/R B-ALL who were treated with humanized CD19-specific CAR-T cells（hCART19s）from May 2016 to September 2021. …”
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“…INTRODUCTION: Brachial plexus birth injury (BPBI) and cerebral palsy (CP) both cause disabling contractures for which no curative treatments exist, largely because contracture pathophysiology is incompletely understood. …”
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“…BACKGROUND AND RATIONALE: Autism spectrum disorder (ASD) is a neuropsychiatric disorder that has no curative treatment. Little is known about the brain laterality in patients with ASD. …”
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“…OBJECTIVE: The aim of this study was to investigate the clinical curative effect of hyperbaric oxygen (HBO) treatment and its mechanism in improving dysfunction following traumatic brain injury (TBI). …”
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“…The proposed model has been evaluated on two publicly available datasets, specifically INbreast and the curated breast imaging subset of digital database for screening mammography (CBIS-DDSM). …”
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“…OBJECTIVES: This study concerns a new technique that aims to achieve precise interstitial brachytherapy of pelvic recurrent tumors under transvaginal ultrasound (US) guidance, enhance the conformity index of the brachytherapy (BT), and improve the curative effect of radiotherapy for gynecological oncology patients with pelvic relapse. …”
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“…To conclude, surgery and chemotherapy, although not curative, can prolong survival in dogs with infiltrative brain tumours. …”
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“…OBJECTIVES: It is widely accepted that surgical resection of localized pulmonary typical carcinoid (TC) tumours remains the primary curative modality. However, the optimal extent of resection remains controversial. …”
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“…Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease without effective curative therapy. Recent evidence shows increased circulating myeloid-derived suppressor cells (MDSCs) in cancer, inflammation, and fibrosis, with some of these cells expressing B7H3. …”
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“…Liberibacter capsica, was curated and annotated here with a total draft genome size of 1.1 MB with 1,036 proteins, which is comparable to other Liberibacter species with complete genomes. …”
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“…METHOD: Patients diagnosed with pathology-confirmed cHCC-CCA, and who underwent curative resection at Tongji hospital between January 2010 and December 2019 were included in this retrospective study. …”
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“…BACKGROUND AND OBJECTIVE: Adenomyosis focus resection has always been the main surgical method for patients with uterine preservation, but its curative effect and surgical method are still controversial. …”
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“…In addition, early active anti-TB treatment can achieve good curative results.…”
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“…The accurate mapping of tumor margins is of particular importance for curative cancer resection and improvement in overall survival. …”
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“…ABSTRACT: DNA repair pathways have been associated with variability in hepatocellular carcinoma (HCC) clinical outcomes, but the mechanism through which DNA repair varies as a function of liver regeneration and other HCC characteristics is poorly understood. We curated a panel of 199 genes representing 15 DNA repair pathways to identify DNA repair expression classes and evaluate their associations with liver features and clinicopathologic variables in The Cancer Genome Atlas (TCGA) HCC study. …”
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“…SIMPLE SUMMARY: Pancreatic cancer has a poor prognosis, even in patients that can be surgically treated with curative intent. An interesting subgroup of resected pancreatic cancers are those associated with pancreatic cystic neoplasms (PCN), since overall survival might differ from pancreatic cancer not associated with PCN. …”
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