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27761por Baysal, Hasan, Siozopoulou, Vasiliki, Zaryouh, Hannah, Hermans, Christophe, Lau, Ho Wa, Lambrechts, Hilde, Fransen, Erik, De Pauw, Ines, Jacobs, Julie, Peeters, Marc, Pauwels, Patrick, Vermorken, Jan Baptist, Smits, Evelien, Lardon, Filip, De Waele, Jorrit, Wouters, An“…This initial investigation was followed by immunohistochemical (IHC) staining for a curated selection of immune cell types and checkpoint ligands markers in tissue samples of 50 advanced stage HNSCC patients. …”
Publicado 2022
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27762por Steen-Olsen, Emma Balch, Pappot, Helle, Green, Allan, Langberg, Henning, Holländer-Mieritz, Cecilie“…A total of 20 Danish patients with cancer ≥18 years old in antineoplastic treatment at Department of Oncology Rigshospitalet Denmark will be recruited from all cancer wards, whether patients are in curative or palliative care. Of these 20 patients, 10 (50%) will be <39 years old, defined as adolescent and young adult, and 10 (50%) will be patients >65 years old, defined as elderly. …”
Publicado 2022
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27763por Yoshimoto-Suzuki, Yuri, Hasegawa, Daisuke, Hosoya, Yosuke, Saito, Go, Nagase, Kyoko, Gunji, Michiyo, Kobayashi, Kyoko, Ishida, Yasushi, Manabe, Atsushi, Ozawa, Miwa“…BACKGROUND: Childhood cancer survivors (CCSs) have a lifelong increased risk of chronic health problems, most of which are associated with the curative therapies. Recent studies have suggested that prospective active screening using comprehensive assessments for CCSs is superior in identifying undiagnosed chronic health problems. …”
Publicado 2022
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27764por Berns, Ellis M., Reid, Daniel B. C., Anderson, George M., Alsoof, Daniel, Shapiro, Benjamin, Zhang, Andrew S., Daniels, Alan H.“…This emphasizes the importance of ensuring that high standards are maintained throughout a physician's practice of maintaining a constant awareness of the fundamentals for effective patient care and of taking care to curate a physician's online presence.…”
Publicado 2022
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27765por Tsering, Thupten, Li, Mingyang, Chen, Yunxi, Nadeau, Amélie, Laskaris, Alexander, Abdouh, Mohamed, Bustamante, Prisca, Burnier, Julia V.“…To fill this gap, we have manually curated a database of EV‐DNA data derived from human biofluids (liquid biopsy) and in‐vitro studies, called the Extracellular Vesicle‐Associated DNA Database (EV‐ADD). …”
Publicado 2022
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27766por Bonfill, Xavier, Martinez-Zapata, María José, Barrionuevo-Rosas, Leslie, Vernooij, Robin WM, Sánchez, María José, Morales-Suárez-Varela, María, De la Cruz, Javier, Emparanza, José Ignacio, Ferrer, Montserrat, Pijoan, José Ignacio, Palou, Joan, Frances, Albert, Madrid, Eva, Coscia, Claudia, Zamora, Javier“…Surgery alone or plus adjuvant therapy were the commonest curative options of bladder cancer. BCG therapy was the adjuvant therapy most frequently administered. …”
Publicado 2022
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27767Publicado 2022“…However, there is a gap in the extensive reuse of individual sensitive data, particularly when mobilising these data requires the linkage of multiple data sources curated in different sites. The gap is greater when it comes to using sensitive data in cross-national research. …”
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27768por Jia, Jinjing, Feng, Luyao, Ye, Siqi, Ping, Ruiyue, Mo, Xiumei, Zhang, Yu, Li, Xiong, Chen, Dacan“…The change in YAP expression in keratinocytes weakened the curative effect of AESS, and AESS exerted its effects through the NF-κB signaling pathway. …”
Publicado 2022
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27769“…BACKGROUND: Surgery is the main curative therapeutic strategy for patients with initial primary lung cancer (IPLC). …”
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27770por Borelli, Beatrice, Antoniotti, Carlotta, Carullo, Martina, Germani, Marco Maria, Conca, Veronica, Masi, Gianluca“…Starting from the results of pivotal clinical trials and based on remarkable findings of CheckMate-142 and Keynote-177 trials, our manuscript provides a complete overview of the treatment with ICIs in dMMR/MSI-H metastatic colorectal cancer (mCRC), also putting an emphasis on current challenges as the optimal duration of ICIs therapy, the role of curative surgery on metastases, and we discuss mechanisms of resistance to anti-PD1 therapy in more detail. …”
Publicado 2022
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27771por Hsu, Wei-Fan, Hsu, Shih-Chao, Chen, Te-Hong, Lin, Chien-Hung, Lin, Ying-Chun, Chang, Yu-Wei, Wang, Hung-Wei, Liao, Yu-Min, Lai, Hsueh-Chou, Peng, Cheng-Yuan“…In patients receiving curative therapy (radiofrequency ablation and surgical resection), the mALBI grade (grade 2 vs. 1 and grade 3 vs. 2) was an independent predictor of OS. …”
Publicado 2022
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27772por Giuffrè, Mauro, Zuliani, Enrico, Visintin, Alessia, Tarchi, Paola, Martingano, Paola, Pizzolato, Riccardo, Bonazza, Deborah, Masutti, Flora, Moretti, Rita, Crocè, Lory Saveria“…Introduction: Hepatocellular carcinoma (HCC) is the sixth most diagnosed malignancy and the fourth leading cause of cancer-related death worldwide, with poor overall survival despite available curative treatments. One of the most crucial factors influencing survival in HCC is recurrence. …”
Publicado 2022
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27773por Ravichandran, Shashank, Avatapalli, SaiSupriya, Narasimhan, Yatindrapravanan, Kaushik, Karishma S., Yennamalli, Ragothaman M.“…In this study, we present an upgraded version of B-AMP, with a focus on existing and novel bacterial biofilm targets. B-AMP v2.0 hosts a curated collection of 2502 biofilm protein targets across 473 bacterial species, with structural protein models and functional annotations from PDB, UniProt, and PubMed databases. …”
Publicado 2022
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27774por Turnic, Tamara Nikolic, Popadic, Viseslav, Klasnja, Slobodan, Sekulic, Ana, Nikolic, Novica, Zivkovic, Vladimir, Jeremic, Nevena, Andjic, Marijana, Draginic, Nevena, Srejovic, Ivan, Jeremic, Jovana, Zdravkovic, Marija, Jakovljevic, Vladimir“…INTRODUCTION: There are still no definite curative or preventive strategies for COVID-19 disease. …”
Publicado 2022
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27775por Barret, Hugo, Bozon, Olivier, Fassot, Guillaume, Chammas, Michel, Coulet, Bertrand, Lazerges, Cyril“…Partial or subtotal scapulectomy should be performed whenever possible because it seems to be associated with a better functional prognosis as well as less poor mental health and emotional acceptance of the patients, even though total scapulectomy may be necessary to obtain a complete curative tumor resection, which is the main goal.…”
Publicado 2022
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27776por Fanning, Joshua, Brand, Jason, Munoz Santa, Isabel, McDonald, Linda, Taylor, Julian, Hollaway, Grant“…Several recently registered fungicides in Australia that combine active ingredients with different modes of actions, have been shown to have curative properties. In this study, in the presence of Ascochyta blight, disease severity, grain yield and quality were measured and the subsequent gross margin for growers calculated in seven field experiments conducted in Victoria (Australia) across three seasons. …”
Publicado 2022
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27777por Cervantes-Alvarez, Eduardo, Vilatoba, Mario, Limon-de la Rosa, Nathaly, Mendez-Guerrero, Osvely, Kershenobich, David, Torre, Aldo, Navarro-Alvarez, Nalu“…BACKGROUND: Liver transplantation for the most critically ill remains controversial; however, it is currently the only curative treatment option. AIM: To assess immediate posttransplant outcomes and compare the short (1 year) and long-term (6 years) posttransplant survival among cirrhotic patients stratified by disease severity. …”
Publicado 2022
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27778por Akamatsu, Maki, Makino, Takuma, Morita, Shinya, Noda, Yohei, Kariya, Shin, Onoda, Tomoo, Ando, Mizuo, Kimata, Yoshihiro, Nishizaki, Kazunori, Okano, Mitsuhiro, Oka, Aiko, Kanai, Kengo, Watanabe, Yoshihiro, Imanishi, Yorihisa“…PATIENTS AND METHODS: The medical data of 32 patients with cT3–4a TSCC who underwent curative surgery between 2010 and 2017 were retrospectively analyzed. …”
Publicado 2022
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27779por Morris, Van K., Overman, Michael J., Lam, Michael, Parseghian, Christine M., Johnson, Benny, Dasari, Arvind, Raghav, Kanwal, Kee, Bryan K., Huey, Ryan, Wolff, Robert A., Shen, John Paul, Li, June, Zorrilla, Isabel, Tzeng, Ching-Wei D., Tran Cao, Hop S., Chun, Yun Shin, Newhook, Timothy E., Vauthey, Nicolas, Duose, Dzifa, Luthra, Raja, Haymaker, Cara, Kopetz, Scott“…Identification of circulating tumor DNA (ctDNA) following curative intent therapies is a surrogate for microscopic residual disease for patients with metastatic colorectal cancer (mCRC). …”
Publicado 2022
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27780por Małkiewicz, Bartosz, Gurwin, Adam, Karwacki, Jakub, Nagi, Krystian, Knecht-Gurwin, Klaudia, Hober, Krzysztof, Łyko, Magdalena, Kowalczyk, Kamil, Krajewski, Wojciech, Kołodziej, Anna, Szydełko, Tomasz“…Most scientific societies do not distinguish cN+ patients in their guidelines; recommendations concern muscle-invasive bladder cancer (MIBC) and differ between associations. The curative treatment that provides the best long-term survival in cN+ patients is a multimodal approach, with a combination of neoadjuvant chemotherapy (NAC) and radical cystectomy (RC) with extended pelvic lymph node dissection (ePLND). …”
Publicado 2022
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