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27781por Idir, Fouzia, Van Ginneken, Sybren, Coppola, Guglielmo A., Grenier, Daniel, Steenackers, Hans P., Bendali, Farida“…Moreover, the extract showed curative potential against mature biofilms grown under conditions mimicking the oral niche. …”
Publicado 2022
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27782por She, Yunlang, He, Bingxi, Wang, Fang, Zhong, Yifan, Wang, Tingting, Liu, Zhenchuan, Yang, Minglei, Yu, Bentong, Deng, Jiajun, Sun, Xiwen, Wu, Chunyan, Hou, Likun, Zhu, Yuming, Yang, Yang, Hu, Hongjie, Dong, Di, Chen, Chang, Tian, Jie“…METHODS: 274 patients undergoing curative surgery after neoadjuvant chemoimmunotherapy for NSCLC at 4 centres from January 2019 to December 2021 were included and divided into a training cohort, an internal validation cohort, and an external validation cohort. …”
Publicado 2022
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27783por Duan, Jin-Ling, Deng, Min-Hua, Xiang, Zhi-Cheng, Hu, Jin-Long, Qu, Chun-Hua, Zhu, Tian-Chen, Xu, Ming-Xing, Chen, Jie-Wei, Xie, Juan-Juan, Xie, Dan, Cai, Mu-Yan, Li, Mei, Liang, Hu“…Background: To evaluate prognostic value of WTAP levels in tumor and paired adjacent non-neoplastic liver tissues (PANLT) for cases of hepatitis B virus (HBV)-positive Asian small hepatocellular carcinoma (sHCC) patients who received curative partial hepatectomy. Method: The investigation with two external cohorts were included. …”
Publicado 2022
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27784por Fründt, Thorben, von Felden, Johann, Krause, Jenny, Heumann, Asmus, Li, Jun, Riethdorf, Sabine, Pantel, Klaus, Huber, Samuel, Lohse, Ansgar W., Wege, Henning, Schulze, Kornelius“…Subsequently, in 11 patients undergoing curative-intended resection for CCA (intrahepatic CCA: n =4; extrahepatic CCA n= 6; gallbladder cancer: n=1), peripheral and central venous blood specimens were obtained to improve detection rate by simultaneous measurement and to elucidate distribution of CTCs in different venous compartments. …”
Publicado 2022
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27785por Kang, Nannan, Liang, Xue, Fan, Buxi, Zhao, Chen, Shen, Beiyu, Ji, Xuemei, Liu, Yu“…Furthermore, TNFα induced the upregulation of ESM1, which promotes metastasis and angiogenesis and regulates matrix metalloprotease-9 (MMP9), vascular endothelial growth factor (VEGF), and delta-like ligand-4 molecules (DLL4). Accordingly, the curative effect of bevacizumab improved by neutralizing ESM1 with high-affinity anti-ESM1 monoclonal antibody 1-2B7 in bevacizumab-resistant mice. …”
Publicado 2022
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27786por Agrawal, Rishabh, Dey, Asoke, Datta, Sujay, Nassar, Ana, Grubb, William, Traughber, Bryan, Biswas, Tithi, Ove, Roger, Podder, Tarun“…Definitive radiation therapy (RT) plays an important role in curative-intent treatment for localized PCa and can be delivered with several different techniques, depending on the availability of resources and patient-specific criteria. …”
Publicado 2022
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27787por Jiang, Justin, Sigmund, Audrey M., Zhao, Qiuhong, Elder, Patrick, Benson, Don M., Vasu, Sumithira, Jaglowski, Samantha, Mims, Alice, Choe, Hannah, Larkin, Karilyn, Brammer, Jonathan E., Wall, Sarah, Grieselhuber, Nicole, Saad, Ayman, Penza, Sam, Efebera, Yvonne A., Sharma, Nidhi“…ABSTRACT: Allogeneic hematopoietic stem cell transplantation (allo-SCT) is a potentially curative treatment for many hematological disorders, but is often complicated by relapse of the underlying disease, graft-versus-host disease (GVHD), and infectious complications. …”
Publicado 2022
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27788“…We included studies on patients undergoing open, laparoscopic, or robotic colorectal cancer surgery for curative intent. We conducted a comprehensive search with online databases (trial registries and ClinicalTrials.gov), other literature sources, and conference proceedings, with no language restriction, up until 12 August 2022. …”
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27789por Zhou, Jin, Lin, Hai-Ping, Xu, Xin, Wang, Xiao-Hang, Rong, Ling, Zhang, Yao, Shen, Lei, Xu, Lei, Qin, Wei-Ting, Ye, Qing, Ma, Xiu-Mei, Bai, Yong-Rui“…Univariate and multivariate analyses were used to identify independent predictors of the clinical curative effect of nCRT. Eventually, nomograms were established for predicting the PD and pCR rates. …”
Publicado 2022
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27790“…METHODS: In the current study, a library of plant secondary metabolites was created by manually curating 120 phytochemicals known to have antimicrobial as well as antiviral properties. …”
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27791por Orell, Helena Kristiina, Pohju, Anne Katariina, Osterlund, Pia, Schwab, Ursula Sonja, Ravasco, Paula, Mäkitie, Antti“…METHODS: The assessment was performed in a series of 65 curative patients with newly diagnosed HNC in a nutrition intervention study. …”
Publicado 2022
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27792por Zandirad, Eric, Teixeira Farinha, Hugo, Barberá-Carbonell, Beatriz, Geinoz, Sandrine, Demartines, Nicolas, Schäfer, Markus, Mantziari, Styliani“…This study retrospectively compared 94 patients with locally advanced adenocarcinoma of the esophago-gastric junction treated with neoadjuvant chemoradiotherapy (n = 27) versus chemotherapy (n = 67) followed by curative surgery. Chemoradiotherapy offered better histological response of the primary tumor, but no benefit in terms of negative resection margins or long-term survival or recurrence. …”
Publicado 2022
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27793por Manderlier, Martin, Navez, Julie, Hein, Matthieu, Engelholm, Jean-Luc, Closset, Jean, Bali, Maria Antonietta, Van Gestel, Dirk, Moretti, Luigi, Van Laethem, Jean-Luc, Bouchart, Christelle“…The only potentially curative treatment is an oncological surgical resection. …”
Publicado 2022
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27794“…We measured multivariate panels of curated genes, soluble factors, and morphometric features for MSC(AT) cultured under varying CPP and licensing conditions, and we benchmarked these against two functional and therapeutically relevant anchor assays – in vitro monocyte/macrophage (MΦ) polarization and in vitro angiogenesis. …”
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27795por Wang, Xianhua, Hu, Shaobo, Su, Fei, Lin, Jie, Duan, Jianghui, Tan, Haidong, Tan, Huangying“…Sometimes, a non-neuroendocrine component is also accompanying these EP-NECs. Curative surgery is suggested for early stage patients while system chemotherapy and locoregional radiotherapy are considered for advanced inoperable disease. …”
Publicado 2022
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27796por Lee, Jung Hwan, Oh, Ju Yeon, Kim, Young-Il, Lee, Jong Yeul, Kim, Chan Gyoo, Choi, Il Ju, Ryu, Keun Won, Kim, Young-Woo, Cho, Soo-Jeong“…This observational study recruited 4264 consecutive patients with early gastric cancer who underwent curative gastrectomy between October 2000 and December 2017 at the National Cancer Center, Korea. …”
Publicado 2022
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27797por Varenna, Massimo, Gatti, Davide, Zucchi, Francesca, Crotti, Chiara, Braga, Vania, Iolascon, Giovanni, Frediani, Bruno, Nannipieri, Fabrizio, Rossini, Maurizio“…BACKGROUND: No data on the permanent and curative effect of bisphosphonate treatment in patients with complex regional pain syndrome type-1 (CRPS-1) are currently available. …”
Publicado 2022
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27798por Rodriguez, Diego Felipe Conejo, Urban, Milan Oldřich, Santaella, Marcela, Gereda, Javier Mauricio, Contreras, Aquiles Darghan, Wenzl, Peter“…After some careful generalization the methodology can be used to: i) verify trait-of-interest transfer from P. acutifolius and P. parvifolius accessions into their hybrids; ii) confirm selected traits as “phenomic markers” which would allow conserving desired physiological traits of exotic parental accessions, without losing key seed characteristics from elite common bean accessions; and iii) propose a quantitative tool that helps genebank curators and breeders to make better-informed decisions based on quantitative analysis.…”
Publicado 2022
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27799por Schmid, Maximilian P., Harrabi, Semi, Herfarth, Klaus, Bruland, Øyvind S., Welzel, Thomas, Haberer, Thomas, Ellerbrock, Malte, Debus, Jürgen, Uhl, Matthias, Seidensaal, Katharina“…Adult patients with primary or locally recurrent pelvic Ewing sarcoma treated with curative intent with protons for primary disease and carbon ions for recurrent disease at the Heidelberg Ion-Beam Therapy Center (HIT) were considered for this retrospective analysis. …”
Publicado 2022
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27800por Ungefroren, Hendrik, Künstner, Axel, Busch, Hauke, Franzenburg, Sören, Luley, Kim, Viol, Fabrice, Schrader, Jörg, Konukiewitz, Björn, Wellner, Ulrich F., Meyhöfer, Sebastian M., Keck, Tobias, Marquardt, Jens-Uwe, Lehnert, Hendrik“…Only a few patients with NETs are amenable to curative tumor resection, and for most patients, only palliative treatments to successfully control the disease or manage symptoms remain, such as with synthetic somatostatin (SST) analogs (SSAs), such as octreotide (OCT) or lanreotide (LAN). …”
Publicado 2022
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