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  1. 27841
    “…Qilongtian (QLT) is a traditional Chinese prescription that is composed of Panax notoginseng, Earthworm, and Rhodiola, and shows the remarkable clinical curative effect of PF. However, the mechanism of QLT remains to be clarified. …”
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    RETRACTED ARTICLE: Qilongtian ameliorate bleomycin-induced pulmonary fibrosis in mice via inhibiting IL-17 signal pathway
  2. 27842
    “…MATERIAL AND METHODS: 25 survivors after curative lung cancer treatment and 17 caregivers underwent a face-to-face semi-structured, audio-recorded interview that was analysed using qualitative content analysis. …”
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    “Scanxiety” and a sense of control: the perspective of lung cancer survivors and their caregivers on follow-up - a qualitative study
  3. 27843
    “…Brentuximab vedotin’s higher drug costs versus MTX or BEX were offset by decreased post-progression and end-stage management costs, and showed a 0.25 QALY gain versus MTX or BEX, and increased the proportion of patients eligible for potentially curative SCT. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12325-023-02470-9.…”
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    Cost-Effectiveness of Brentuximab Vedotin Versus Physician’s Choice of Methotrexate or Bexarotene for the Treatment of Cutaneous T-cell Lymphoma in Canada
  4. 27844
    “…BACKGROUND & AIMS: In this retrospective study, we aimed to elucidate how the initial recurrence site influences the post-recurrence survival (PRS) after the curative resection of colorectal cancer. PATIENTS AND METHODS: We collected samples from patients with stage I-III colorectal adenocarcinoma who were admitted to Yunnan Cancer Hospital from January 2008 to December 2019. …”
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    Influence of the initial recurrence site on prognosis after radical surgery for colorectal cancer: a retrospective cohort study
  5. 27845
    “…METHODS: In this retrospective study, 1050 eligible patients with stage II–IVA NPC, who completed curative IMRT and underwent pretreatment and postradiotherapy (-7 to +28 days after IMRT) EBV DNA testing, were enrolled from 2012 to 2017. …”
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    Tumor residue in patients with stage II–IVA nasopharyngeal carcinoma who received intensity-modulated radiation therapy: development and validation of a prediction nomogram integrating postradiotherapy plasma Epstein–Barr virus deoxyribonucleic acid, clinical stage, and radiotherapy dose
  6. 27846
    “…METHODS: The expressions of PRL-3 in cancer tissues isolated from 114 HCC patients, who underwent curative hepatectomy from May to November in 2008, were analyzed by immunohistochemistry, and its prognostic significance was evaluated. …”
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    Phosphatase regenerating liver 3 participates in Integrinβ1/FAK-Src/MAPK signaling pathway and contributes to the regulation of malignant behaviors in hepatocellular carcinoma cells
  7. 27847
    “…This framework is composed of three stand-alone yet connected components; an interactive visualization (COVID-MVP), a manually curated functional annotation database (pokay), and a genomic analysis workflow (nf-ncov-voc). …”
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    IDENTIFYING THE NEXT MUTATION OF CONCERN – EXPLOITING GENOMICS FOR TRACKING SARS-COV-2 MUTATIONS AND THEIR BIOLOGICAL IMPACT IN CANADA
  8. 27848
    “…This was in large part made possible through the careful curation of 16S rRNA gene amplicon data and the incorporation of a QMP-based methods. …”
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    Genome-wide mapping of gene-microbe interactions in the murine lung microbiota based on quantitative microbial profiling
  9. 27849
    “…METHODS: A CNN model was trained on a curated subset of a public pulmonary embolism CT dataset (RSPECT) with 755 CTPA studies, including patient-level labels of CPE, acute pulmonary embolism (APE), or no pulmonary embolism. …”
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    Leveraging open dataset and transfer learning for accurate recognition of chronic pulmonary embolism from CT angiogram maximum intensity projection images
  10. 27850
    “…In head and neck squamous cell carcinoma (HNSCC) targeting of the PD-1/PD-L1 (B7-H1) axis is approved in recurrent/metastatic disease and is being explored in the curative setting. Here, we evaluated two related members of the B7 family, B7-H3 & B7-H4, for their prognostic impact under standard treatment. …”
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    The prognostic impact of B7-H3 and B7-H4 in head and neck squamous cell carcinoma
  11. 27851
    “…CONCLUSIONS: This study primarily revealed that the preventive and curative effects of ACEI treatment on DCM could be realized through multiple targets and pathways, and its mechanism of action is related to genes such as TNF, vascular endothelial growth factor A (VEGFA), interleukin 6 (IL6), C-C motif chemokine ligand 2 (CCL2), Cyclin D1 (CCND1), and AKT serine/threonine kinase 1 (AKT1), with immune- and inflammation-related signaling pathways involvement.…”
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    Mechanism of angiotensin-converting enzyme inhibitors in the treatment of dilated cardiomyopathy based on a protein interaction network and molecular docking
  12. 27852
    por Murthy, Guru Subramanian Guru, Kim, Soyoung, Estrada-Merly, Noel, Abid, Muhammad Bilal, Aljurf, Mahmoud, Assal, Amer, Badar, Talha, Badawy, Sherif M., Ballen, Karen, Beitinjaneh, Amer, Cerny, Jan, Chhabra, Saurabh, DeFilipp, Zachariah, Dholaria, Bhagirathbhai, Perez, Miguel Angel Diaz, Farhan, Shatha, Freytes, Cesar O., Gale, Robert Peter, Ganguly, Siddhartha, Gupta, Vikas, Grunwald, Michael R., Hamad, Nada, Hildebrandt, Gerhard C., Inamoto, Yoshihiro, Jain, Tania, Jamy, Omer, Juckett, Mark, Kalaycio, Matt, Krem, Maxwell M., Lazarus, Hillard M, Litzow, Mark, Munker, Reinhold, Murthy, Hemant S., Nathan, Sunita, Nishihori, Taiga, Ortí, Guillermo, Patel, Sagar S., van der Poel, Marjolein, Rizzieri, David A, Savani, Bipin N, Seo, Sachiko, Solh, Melhem, Verdonck, Leo F., Wirk, Baldeep, Yared, Jean A., Nakamura, Ryotaro, Oran, Betul, Scott, Bart, Saber, Wael
    Publicado 2023
    “…Allogeneic hematopoietic cell transplantation (allo-HCT) remains the only curative treatment for myelofibrosis. However, the optimal conditioning regimen either with reduced-intensity conditioning (RIC) or myeloablative conditioning (MAC) is not well known. …”
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    Association between the choice of the conditioning regimen and outcomes of allogeneic hematopoietic cell transplantation for myelofibrosis
  13. 27853
    “…Recent developments show RNA sequencing (RNA-seq) is promising for genome-wide detection of fusion products but hindered by many false positives that require extensive manual curation and impede discovery of pathogenic fusions. …”
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    Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS
  14. 27854
    “…CONCLUSIONS: A combination of necessary preventive and curative activities may prove beneficial both for targeted populations and for health system strengthening in the long run. …”
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    Seasonal malaria chemoprevention in Africa and China’s upgraded role as a contributor: a scoping review
  15. 27855
    “…The use of currently available cost-efficient sequencing strategies allows for the generation of a substantial amount of sequence data for dense taxonomic samplings, which together with well-curated geographic information and biogeographic models allow us to formally test the mode and tempo of dispersal events occurring in quick succession. …”
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    Plastome phylogenomics reveals an early Pliocene North- and Central America colonization by long-distance dispersal from South America of a highly diverse bromeliad lineage
  16. 27856
    “…METHODS: A genome-wide identification and curation were performed to screen the FAR family members of Haemonchus contortus. …”
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    Fatty acid- and retinol-binding protein 6 does not control worm fatty acid content in Caenorhabditis elegans but might play a role in Haemonchus contortus parasitism
  17. 27857
    “…Patients with ≥ 4 positive axillary lymph nodes (N +) or 1–3 N + with tumor size ≥ 5 cm and/or histologic grade 3 and/or Ki67 ≥ 20%, who had undergone surgery with curative intent and had received anthracyclines ± taxanes and endocrine therapy in the neoadjuvant and /or adjuvant setting were included. …”
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    Long-term outcomes of high-risk HR-positive and HER2-negative early breast cancer patients from GEICAM adjuvant studies and El Álamo IV registry
  18. 27858
    por Lesmann, Hellen, Lyon, Gholson J., Caro, Pilar, Abdelrazek, Ibrahim M., Moosa, Shahida, Pantel, Jean Tori, Hagen, Merle ten, Rosnev, Stanislav, Kamphans, Tom, Meiswinkel, Wolfgang, Li, Jing-Mei, Klinkhammer, Hannah, Hustinx, Alexander, Javanmardi, Behnam, Knaus, Alexej, Uwineza, Annette, Knopp, Cordula, Marchi, Elaine, Elbracht, Miriam, Mattern, Larissa, Jamra, Rami Abou, Velmans, Clara, Strehlow, Vincent, Nabil, Amira, Graziano, Claudio, Artem, Borovikov, Schnabel, Franziska, Heuft, Lara, Herrmann, Vera, Höller, Matthias, Alaaeldin, Khoshoua, Jezela-Stanek, Aleksandra, Mohamed, Amal, Lasa-Aranzasti, Amaia, Elmakkawy, Gehad, Safwat, Sylvia, Ebstein, Frédéric, Küry, Sébastien, Arlt, Annabelle, Marbach, Felix, Netzer, Christian, Kaptain, Sophia, Weiland, Hannah, Devriendt, Koen, Gripp, Karen W., Mücke, Martin, Verloes, Alain, Schaaf, Christian P., Nellåker, Christoffer, Solomon, Benjamin D., Waikel, Rebekah, Abdalla, Ebtesam, Nöthen, Markus M., Krawitz, Peter M., Hsieh, Tzung-Chien
    Publicado 2023
    “…In the beginning, data was mainly collected by curators gathering images from the literature. Currently, clinicians and individuals recruited from patient support groups provide their previously unpublished data. …”
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    GestaltMatcher Database - a FAIR database for medical imaging data of rare disorders
  19. 27859
    “…PURPOSE: Radiofrequency ablation (RFA) is a curative treatment option for small lung metastases, which conventionally involves multiple freehand manipulations until the treating electrode is satisfactorily positioned. …”
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    Robotic versus freehand CT-guided radiofrequency ablation of pulmonary metastases: a comparative cohort study
  20. 27860
    “…RESULTS: The 60 patients who received curative-intent irradiation for primary and metastatic sites showed a 5-year OS rate of 51.4% and a 5-year PFS rate of 25.9%. …”
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    Definitive irradiation as a first treatment strategy for primary and metastatic sites of newly diagnosed IVB cervical cancer that presented with synchronous oligometastases
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