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  1. 28021
    “…METHODS: Of the 1483 patients who underwent ESD for early gastric cancer between January 2012 and April 2020, we retrospectively analyzed 151 patients diagnosed as having a lesion not meeting the curative criteria after ESD. Of these patients, 100 underwent additional gastrectomy, and 51 were observed without surgery. …”
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    Evaluation of additional gastrectomy after noncurative endoscopic submucosal dissection for early gastric cancer
  2. 28022
    “…Here, we investigate the RNA–protein interactions of the Cas13-based systems by curating the validation dataset of Cas13 protein and CRISPR repeat pairs that are experimentally validated to interact, and the candidate dataset of CRISPR repeats that reside on the same genome as the currently known Cas13 proteins. …”
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    In silico optimization of RNA–protein interactions for CRISPR-Cas13-based antimicrobials
  3. 28023
    “…BACKGROUND: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an important curative therapy for adult acute lymphoblastic leukemia (ALL). …”
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    Unrelated cord blood transplantation vs. HLA-matched sibling transplantation for adults with B-cell acute lymphoblastic leukemia in complete remission: superior OS for patients with long-term survival
  4. 28024
    “…METHODS: This study included 181 gastric cancer patients who underwent curative intent surgery in Central Finland Central Hospital between years 2005 and 2021 for gastric or esophagogastric junction adenocarcinoma. …”
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    Implementation of Multimodality Therapy and Minimally Invasive Surgery: Short- and Long-term Outcomes of Gastric Cancer Surgery in Medium-Volume Center
  5. 28025
    “…Advances in musculoskeletal (MSK) research have been successfully curated into widely endorsed evidence-based recommendations and guidelines. …”
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    Patient and public involvement in implementation of evidence-based guidance for musculoskeletal conditions: a scoping review of current advances and gaps
  6. 28026
    “…In this cohort, 66 patients were treated with a curative intent, of which 51 are on follow-up {34 patients are disease-free (MTD – 18.5, 10 to 43), seven had either a residual disease or locoregional recurrence (MTD – 22, 10 to 32), seven had distant metastasis (MTD – 18, 15 to 47), and three patients died (MTD – 20, 8 to 27)}. …”
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    Impact of Radiation Treatment Delay Due to COVID-19 Pandemic
  7. 28027
    “…One patient (7.7%) died of GTC recurrence, 15.4 years after the initial non-curative ER date; 3 (23.1%) patients died of esophageal cancer recurrence, and 3 (23.1%) died of other organ malignancies. …”
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    Feasibility, efficacy, and cautionary note of endoscopic resection for gastric tube cancer after esophagectomy
  8. 28028
    “…INTRODUCTION: The only curative treatment for most gastric cancer is radical gastrectomy with D2 lymphadenectomy (LAD). …”
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    Minimally invasivE versus open total GAstrectomy (MEGA): study protocol for a multicentre randomised controlled trial (DRKS00025765)
  9. 28029
    “…Sequence alignment was performed against a set of previously published and curated sequences, and phylogenetic analysis based on the maximum-likelihood and Bayesian inference approaches was conducted. …”
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    Sequencing of hsp70 for discernment of species from the Leishmania (Viannia) guyanensis complex from endemic areas in Colombia
  10. 28030
    “…This paper will describe the data flows, database, and frontend public dashboard, as well as the challenges experienced in data acquisition, curation and compilation and the lessons learnt in overcoming these. …”
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    The World Health Organization COVID-19 surveillance database
  11. 28031
    “…For the MSC source aspect, adipose mesenchymal stem cells (ADMSCs) and umbilical cord mesenchymal stem cells (UBMSCs) showed a better curative effect on pain relief and function improvement compared with bone marrow mesenchymal stem cells (BMMSCs). …”
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    Intra-articular injection choice for osteoarthritis: making sense of cell source—an updated systematic review and dual network meta-analysis
  12. 28032
    “…OBJECTIVE: This study aimed to develop a patient decision aid (PtDA), integrating personalized risk calculations on risks for recurrences, to support SDM for personalized surveillance after curative treatment for invasive breast cancer. METHODS: For the development of the PtDA, the International Patient Decision Aids Standards development process was combined with a mixed methods design inspired by the development process of previously developed PtDAs. …”
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    Supporting Shared Decision-making About Surveillance After Breast Cancer With Personalized Recurrence Risk Calculations: Development of a Patient Decision Aid Using the International Patient Decision AIDS Standards Development Process in Combination With a Mixed Methods Design
  13. 28033
    “…The major advantages of our approach are as follows: (1) synthetic training data can be generated virtually instantly and on demand; (2) these synthetic images are accompanied by perfect ground truth positions of cells, meaning no data curation is required; (3) different biological conditions, imaging platforms, and imaging modalities can be rapidly simulated, meaning any change in one’s experimental setup no longer requires the laborious process of manually generating new training data for each change. …”
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    Synthetic Micrographs of Bacteria (SyMBac) allows accurate segmentation of bacterial cells using deep neural networks
  14. 28034
    “…CONCLUSION: This pilot study indicates that pre-surgery (18)F-JK-PSMA-7 PET/CT provides valuable information in intermediate- and high-risk PCa, for surgery planning with curative intent.…”
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    (18)F-JK-PSMA-7 PET/CT for staging intermediate- or high-risk prostate cancer patients before radical prostatectomy: a pilot study
  15. 28035
    “…INTRODUCTION: Radical gastrectomy has traditionally been the pillar treatment with curative intent for malignant tumors of the stomach. …”
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    Laparoscopic and open gastrectomy for locally advanced gastric cancer: a retrospective analysis in Colombia
  16. 28036
    “…Efforts are currently ongoing in collaboration with ARIDHIA and ADDI to harmonize, integrate, and curate all available clinical data from the PNHS PCs, which will become openly accessible to the wider scientific community.…”
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    The amyloid imaging for the prevention of Alzheimer's disease consortium: A European collaboration with global impact
  17. 28037
    “…Les patients étaient traités par oxygénothérapie, corticothérapie, anti-coagulation curative et opothérapie thyroïdienne avec évolution miraculeuse et sortie à domicilie entre j20 et j40. …”
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    Trisomie 21 et infection grave à COVID-19 : pensez à une hypothyroïdie !
  18. 28038
    “…Often, preoperative tissue diagnosis is not available, and surgery is both diagnostic and curative. Intraoperatively, emphasis should be on complete resection with negative margins. …”
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    Surgical considerations in the resection of solitary fibrous tumors of the pleura
  19. 28039
    “…While surgical resection can be potentially curative, many patients are not candidates for operative intervention due to widespread metastases or the degree of hepatic involvement by the NE cancers. …”
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    2018 Synaptic vesicle 2 receptors as a novel targets for neuroendocrine cancer therapy
  20. 28040
    “…As a proof of concept, a reduction-responsive nanoparticle (NP) platform was engineered for effective LCN2 siRNA (siLCN2) delivery, and a tongue orthotopic xenograft model as well as an EGFR-positive patient-derived xenograft (PDX) model were applied to investigate the curative effect of siLCN2. RESULTS: We identified lipocalin-2 (LCN2), which is upregulated in OSCC metastasis and EGFR resistance. …”
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    Silencing LCN2 suppresses oral squamous cell carcinoma progression by reducing EGFR signal activation and recycling
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