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28061“…BACKGROUND: Curated databases of genetic variants assist clinicians and researchers in interpreting genetic variation. …”
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28062por Wang, Chan, Ahn, Jiyoung, Tarpey, Thaddeus, Yi, Stella S., Hayes, Richard B., Li, Huilin“…RESULTS: Through three body mass index (BMI) studies selected from the curatedMetagenomicData 3.4.2 package and the American gut project: China vs. …”
Publicado 2023
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28063por Wang, Zhizhou, Yuan, Qihang, Chen, Xu, Luo, Fei, Shi, Xueying, Guo, Fangyue, Ren, Jie, Li, Shuang, Shang, Dong“…Our findings also revealed that FTI-277, a farnesyltransferase inhibitor, had a better curative effect in high-risk patients, while MK-2206, an Akt allosteric inhibitor, had a superior therapeutic effect in low-risk patients. …”
Publicado 2023
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28064“…According to Zook score, the curative effect of fifty-six cases were all excellent or good with 100% excellent and good rate, and all patients had beautiful appearances and good function of damaged fingertips. …”
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28065por Abdel Jalil, Riad, Abdallah, Farah A., Obeid, Zeinab, Harb, Ahmad Khaled, Abou Chaar, Mohamad K., Shannies, Tariq Bassem, El-Edwan, Ahed, Haddad, Hussam, Ghraibeh, Azza, Abu-Shanab, Ahmad“…METHODS: Demographic and clinical data from patients who presented to a tertiary cancer center between January 2015–October 2021 with a diagnosis of thymoma and underwent curative surgical resection was collected. Computed tomography scan was used to delineate clinical staging, tumor size and to detect post-therapeutic variations in tumor burden. …”
Publicado 2023
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28066“…Although it is widely used clinically and has a remarkable curative effect, the mechanism of RP treatment for endometriosis (EMs) remains unclear due to its complicated components. …”
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28067por Hutton, Lauren, Jenkins, Louis Stander, Mash, Robert, von Pressentin, Klaus, Reid, Steve, Morgan, Jennie, Kapp, Paul“…Overall, eight interns, four managers, four supervisors and four intern curators were included. Individual semi-structured interviews were audio-recorded and the transcripts were thematically analysed using the framework method and Atlas-ti software. …”
Publicado 2023
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28068“…It is always resistant to existing treatments, including surgical resection, postoperative radiotherapy, and chemotherapy, which leads to a dismal prognosis and a high relapse rate. Therefore, novel curative therapies are urgently needed for GBM. Chimeric antigen receptor T (CAR-T) cell therapy has significantly improved life expectancy for hematological malignancies patients, and thus it increases the interest in applying CAR-T cell therapy for solid tumors. …”
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28069por Mougeot, Jean-Luc C., Beckman, Micaela F., Hovan, Allan J., Hasséus, Bengt, Legert, Karin Garming, Johansson, Jan-Erik, von Bültzingslöwen, Inger, Brennan, Michael T., Bahrani Mougeot, Farah“…GENE2FUNC analysis of multi-marker SNP sets identified one positional gene set including lead SNPs for KANK1 and KDM4C and two curated gene sets including lead SNPs for PTPRD, KDM4C, and/or KANK1. …”
Publicado 2023
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28070por van Eck van der Sluijs, Jesper, van Ens, Diede, Brummelman, Jolanda, Heister, Daan, Sareen, Aastha, Truijen, Lisa, van Ingen Schenau, Dorette S., Heemskerk, Mirjam H. M., Griffioen, Marieke, Kester, Michel G. D., Schaap, Nicolaas P. M., Jansen, Joop H., van der Waart, Anniek B., Dolstra, Harry, Hobo, Willemijn“…Allogeneic stem cell transplantation (alloSCT) can be curative for hemato-oncology patients due to effective graft-versus-tumor immunity. …”
Publicado 2023
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28071por Doleschal, Bernhard, Kirchweger, Patrick, Schwendinger, Simon, Kupferthaler, Alexander, Burghofer, Jonathan, Webersinke, Gerald, Jukic, Emina, Wundsam, Helwig, Biebl, Matthias, Petzer, Andreas, Rumpold, Holger“…BACKGROUND: Serial analysis of circulating tumor DNA (ctDNA) levels is a promising tool for both relapse prediction in the curative setting, as well as predicting clinical benefit from systemic treatment in metastasic colorectal cancer (mCRC). …”
Publicado 2023
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28072por Mao, Xin-Cheng, Shi, Shuo, Yan, Lun-Jie, Wang, Han-Chao, Ding, Zi-Niu, Liu, Hui, Pan, Guo-Qiang, Zhang, Xiao, Han, Cheng-Long, Tian, Bao-Wen, Wang, Dong-Xu, Tan, Si-Yu, Dong, Zhao-Ru, Yan, Yu-Chuan, Li, Tao“…METHODS: One hundred fifty-eight HCC patients from institution A (training cohort) and 53 HCC patients from institution B (validation cohort) were included, all of whom underwent preoperative CT scan and curative resection with confirmed pathological diagnoses. …”
Publicado 2023
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28073“…METHODS: From March 2021 to December 2021, patients who underwent curative PD at our institution due to periampullary lesions were enrolled. …”
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28074por Boligarla, Srikanth, Laison, Elda Kokoè Elolo, Li, Jiaxin, Mahadevan, Raja, Ng, Austen, Lin, Yangming, Thioub, Mamadou Yamar, Huang, Bruce, Ibrahim, Mohamed Hamza, Nasri, Bouchra“…A subset of tweets were semi-automatically labelled as relevant or irrelevant to Lyme disease using a set of precise keywords, and the remaining portion were manually labelled, yielding a curated labelled dataset of 77, 500 tweets. (2) This labelled data set was used to train, validate, and test various combinations of NLP word embedding methods and prominent ML classification models, such as TF-IDF and logistic regression, Word2vec and XGboost, and BERTweet, among others, to identify potential Lyme disease tweets. (3) Lastly, the presence of spatio-temporal patterns in the US over a 10-year period were studied. …”
Publicado 2023
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28075por Foster, James S., Balachandran, Manasi, Hancock, Trevor J., Martin, Emily B., Macy, Sallie, Wooliver, Craig, Richey, Tina, Stuckey, Alan, Williams, Angela D., Jackson, Joseph W., Kennel, Stephen J., Wall, Jonathan S.“…Current treatment focuses on reducing amyloid precursor protein synthesis and slowing amyloid deposition. However, curative interventions will likely also require removal of preexisting amyloid deposits to restore organ function. …”
Publicado 2023
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28076por Lei, Yangyang, Zhou, Boxuan, Meng, Xiangzhi, Liang, Mei, Song, Weijian, Liang, Yicheng, Gao, Yushun, Wang, Minghui“…BACKGROUND: Lipid metabolism is a key factor in tumorigenesis and drug resistance, and models related to lipid metabolism have shown potential to predict survival and curative effects of adjuvant therapy in various cancers. …”
Publicado 2023
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28077por Song, Ji Hyeong, Oh, Tae Jeong, An, Sungwhan, Lee, Kyung Ha, Kim, Ji Yeon, Kim, Jin Soo“…METHODS: In this prospective study, we enrolled 151 patients with CRC who underwent curative surgical resection between September 2016 and May 2020. …”
Publicado 2023
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28078“…We found that AI education is a critical step to enable meaningful patient engagement within this field. We have curated recommendations into a framework for the field to learn from and implement in future development. …”
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28079por Beaufils, Camille, Proulx, Catherine, Blincoe, Annaliesse, Teira, Pierre, Bittencourt, Henrique, Cellot, Sonia, Duval, Michel, Morin, Marie-Paule, De Bruycker, Jean Jacques, Couture, Julie, Samaan, Kathryn, Decaluwe, Hélène, Kleiber, Niina, El-Jalbout, Ramy, Touzot, Fabien, Haddad, Elie, Barsalou, Julie“…Allo-HSCT is a potential curative option for severe/refractory sJIA. It should be considered only after failure of conventional sJIA treatments and when an HLA-matched donor is available in order to lower transplant-related mortality. …”
Publicado 2023
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28080por Wang, Huaijie, Xie, Chong, Lin, Weilong, Wang, Peihua, Yang, Weijia, Guo, Zhengtuan“…Surgery alone can be curative in early stage FAVA.…”
Publicado 2023
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