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  1. 28101
    “…The decrease of PDSS2 mRNA expression in GC tissues (less than half the level of expression detected in the corresponding normal adjacent tissues) correlated significantly with elevated levels of carbohydrate antigen 19-9 (P = 0.015), lymph node metastasis (P = 0.022), and shorter recurrence-free survival after curative resection (P = 0.022). Further, multivariate analysis identified PDSS2 mRNA expression as an independent prognostic factor (hazard ratio 1.95, 95% confidence interval 1.22–3.09, P = 0.005), and its expression pattern and prognostic significance were similar among three GC subtypes. …”
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    Decreased expression of prenyl diphosphate synthase subunit 2 correlates with reduced survival of patients with gastric cancer
  2. 28102
    “…Five assessment points, including baseline, 2 and 4 weeks after treatment, 6 and 12 weeks after follow-up, are set to dynamically observe the changes of curative effects. Primary outcome measures are the differences in the score on both the China rehabilitation research center aphasia examination (CRRCAE) and Boston diagnostic aphasia examination - Chinese version (BDAE-C) after intervention and follow-up. …”
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    Community-applied research of a traditional Chinese medicine rehabilitation scheme on Broca’s aphasia after stroke: study protocol for a randomized controlled trial
  3. 28103
    “…The assembly and annotation has been deposited in GenBank (BioProject: PRJNA10791). The heavily curated chromosomal sequences and associated gene models of Medicago will serve as a better reference for legume biology and comparative genomics.…”
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    An improved genome release (version Mt4.0) for the model legume Medicago truncatula
  4. 28104
    “…METHODS: We searched six databases for quantitative, qualitative, and mixed-methods studies that included CHWs working in promotional, preventive or curative primary health care services in LMICs. We differentiated CHW performance outcome measures at two levels: CHW level and end-user level. …”
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    How does context influence performance of community health workers in low- and middle-income countries? Evidence from the literature
  5. 28105
    “…Systematic recording of relevant clinical data, curation of a gene–phenotype knowledge base, and development of clinical decision support software are needed in addition to automated exclusion of almost all variants, which is crucial for scalable prioritisation and review of possible diagnostic variants. …”
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    Genetic diagnosis of developmental disorders in the DDD study: a scalable analysis of genome-wide research data
  6. 28106
    “…Automatic functional annotation and manual curation were performed. Each gene was attributed to either the core genome or an accessory genome. …”
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    Mutations and genomic islands can explain the strain dependency of sugar utilization in 21 strains of Propionibacterium freudenreichii
  7. 28107
    “…RESULTS: In this study, we curated and categorized 27,558 Mendelian disease variants, 20,964 complex disease variants, 5,809 cancer predisposing germline variants, and 43,364 recurrent cancer somatic mutations. …”
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    Disease-associated variants in different categories of disease located in distinct regulatory elements
  8. 28108
    “…METHODS: Cross-sectional surveys were conducted from 2010 to 2011 at HFs that provide curative care as part of outpatient activities in two districts located in the middle belt of Ghana to coincide with the periods of low and high malaria transmission seasons. …”
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    Provider compliance to artemisinin-based combination therapy at primary health care facilities in the middle belt of Ghana
  9. 28109
    “…CONCLUSION: As long as the treatment plan is fully prepared, the surgical option can achieve a satisfactory curative effect in treating juvenile spinal tuberculosis despite some complications.…”
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    Treatment effect, postoperative complications, and their reasons in juvenile thoracic and lumbar spinal tuberculosis surgery
  10. 28110
    “…METHODS: The characteristics of LA-NSCLC patients treated with curative concurrent CRT from 2001 to 2010 were retrospectively reviewed. …”
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    Consolidation chemotherapy may improve survival for patients with locally advanced non-small-cell lung cancer receiving concurrent chemoradiotherapy - retrospective analysis of 203 cases
  11. 28111
    “…In 81 cases primary surgical resection was the only and curative treatment, and in five cases progression of the disease was observed. …”
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    Transcriptional profiles of pilocytic astrocytoma are related to their three different locations, but not to radiological tumor features
  12. 28112
    “…BACKGROUND: By profession, healthcare workers (HCWs) attend to clients and patients through a variety of preventive and curative services. However, while their attention is focused on providing care, they are vulnerable to hazards that could be detrimental to their health and well-being. …”
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    Knowledge, attitudes and perceptions of occupational hazards and safety practices in Nigerian healthcare workers
  13. 28113
    “…Combining the constraints on genes from the statistical interaction of their loci and further using curated protein interaction networks, the number of candidate genes for association of miRNAs was reduced to a set of several genes. …”
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    Dissecting genetics of cutaneous miRNA in a mouse model of an autoimmune blistering disease
  14. 28114
    “…Allogeneic hematopoietic stem cell transplantation is currently the only curative treatment option for JMML; however, disease recurrence is a major cause of treatment failure. …”
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    Anti-proliferative effects of T cells expressing a ligand-based chimeric antigen receptor against CD116 on CD34(+) cells of juvenile myelomonocytic leukemia
  15. 28115
    “…From the medical record audit, 29 % of Aboriginal people with NSCLC had potentially curative treatment, 45 % had palliative radiotherapy/chemotherapy and 26 % had no active treatment. …”
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    Lung cancer treatment and mortality for Aboriginal people in New South Wales, Australia: results from a population-based record linkage study and medical record audit
  16. 28116
    “…CONCLUSIONS: CHWs promote equitable access to health promotion, disease prevention and use of curative services at household level. However, care must be taken by policymakers and implementers to take into account factors which can influence the equity of services during planning and implementation of CHW programmes. …”
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    How equitable are community health worker programmes and which programme features influence equity of community health worker services? A systematic review
  17. 28117
    “…BACKGROUND: The Mexican healthcare system is under increasing strain due to the rising prevalence of non-communicable diseases (especially type 2 diabetes), mounting costs, and a reactive curative approach focused on treating existing diseases and their complications rather than preventing them. …”
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    Enablers and inhibitors of the implementation of the Casalud Model, a Mexican innovative healthcare model for non-communicable disease prevention and control
  18. 28118
    “…CONCLUSIONS: Sequencing the V1–V3 region of the 16S rRNA gene on the MiSeq platform may require additional sequence curation in silico, and improved error rates and diversity estimates show that removing low-frequency sequences is reasonable. …”
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    Pipeline for amplifying and analyzing amplicons of the V1–V3 region of the 16S rRNA gene
  19. 28119
    por Hardisty, Alex R., Bacall, Finn, Beard, Niall, Balcázar-Vargas, Maria-Paula, Balech, Bachir, Barcza, Zoltán, Bourlat, Sarah J., De Giovanni, Renato, de Jong, Yde, De Leo, Francesca, Dobor, Laura, Donvito, Giacinto, Fellows, Donal, Guerra, Antonio Fernandez, Ferreira, Nuno, Fetyukova, Yuliya, Fosso, Bruno, Giddy, Jonathan, Goble, Carole, Güntsch, Anton, Haines, Robert, Ernst, Vera Hernández, Hettling, Hannes, Hidy, Dóra, Horváth, Ferenc, Ittzés, Dóra, Ittzés, Péter, Jones, Andrew, Kottmann, Renzo, Kulawik, Robert, Leidenberger, Sonja, Lyytikäinen-Saarenmaa, Päivi, Mathew, Cherian, Morrison, Norman, Nenadic, Aleksandra, de la Hidalga, Abraham Nieva, Obst, Matthias, Oostermeijer, Gerard, Paymal, Elisabeth, Pesole, Graziano, Pinto, Salvatore, Poigné, Axel, Fernandez, Francisco Quevedo, Santamaria, Monica, Saarenmaa, Hannu, Sipos, Gergely, Sylla, Karl-Heinz, Tähtinen, Marko, Vicario, Saverio, Vos, Rutger Aldo, Williams, Alan R., Yilmaz, Pelin
    Publicado 2016
    “…BioVeL includes functions for accessing and analysing data through curated Web services; for performing complex in silico analysis through exposure of R programs, workflows, and batch processing functions; for on-line collaboration through sharing of workflows and workflow runs; for experiment documentation through reproducibility and repeatability; and for computational support via seamless connections to supporting computing infrastructures. …”
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    BioVeL: a virtual laboratory for data analysis and modelling in biodiversity science and ecology
  20. 28120
    “…The relatively high prevalence of potentially curative kidney diseases in elderly individuals implicates the importance of renal biopsy in these patients. …”
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    Kidney disease in the elderly: biopsy based data from 14 renal centers in Poland
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