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28281por Garg, Samir, Dewangan, Mukesh, Nanda, Prabodh, C, Krishnendhu, Sahu, Ashu, Xalxo, Lalita“…The time-use was well balanced between roles of service-linkage, providing health education and curative care directly, COVID-19 related work and action on social determinants of health. …”
Publicado 2022
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28282por Dolzhenko, Egor, Weisburd, Ben, Ibañez, Kristina, Rajan-Babu, Indhu-Shree, Anyansi, Christine, Bennett, Mark F., Billingsley, Kimberley, Carroll, Ashley, Clamons, Samuel, Danzi, Matt C., Deshpande, Viraj, Ding, Jinhui, Fazal, Sarah, Halman, Andreas, Jadhav, Bharati, Qiu, Yunjiang, Richmond, Phillip A., Saunders, Christopher T., Scheffler, Konrad, van Vugt, Joke J. F. A., Zwamborn, Ramona R. A. J., Chong, Samuel S., Friedman, Jan M., Tucci, Arianna, Rehm, Heidi L., Eberle, Michael A.“…RESULTS: We implemented REViewer, a computational method for visualization of sequencing data in genomic regions containing long repeat expansions and FlipBook, a companion image viewer designed for manual curation of large collections of REViewer images. To generate a read pileup, REViewer reconstructs local haplotype sequences and distributes reads to these haplotypes in a way that is most consistent with the fragment lengths and evenness of read coverage. …”
Publicado 2022
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28283por Bao, Weiwei, Yang, Jiajia, Li, Mingna, Chen, Kang, Ma, Zheng, Bai, Yuehong, Xu, Yiming“…The decrease in active ankle range of motion and cross-sectional area of the lower leg Exp I and Exp II was smaller than that in the control group (P < 0.05), and the decrease in Exp I was smaller than that of Exp II (all P < 0.05). The curative effect in Exp I was better than in Exp II. …”
Publicado 2022
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28284por Henriksen, Tenna Vesterman, Tarazona, Noelia, Frydendahl, Amanda, Reinert, Thomas, Gimeno-Valiente, Francisco, Carbonell-Asins, Juan Antonio, Sharma, Shruti, Renner, Derrick, Hafez, Dina, Roda, Desamparados, Huerta, Marisol, Roselló, Susana, Madsen, Anders Husted, Løve, Uffe S., Andersen, Per Vadgaard, Thorlacius-Ussing, Ole, Iversen, Lene Hjerrild, Gotschalck, Kåre Andersson, Sethi, Himanshu, Aleshin, Alexey, Cervantes, Andres, Andersen, Claus Lindbjerg“…EXPERIMENTAL DESIGN: We recruited 168 patients with stage III colorectal cancer treated with curative intent at Danish and Spanish hospitals between 2014 and 2019. …”
Publicado 2022
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28285por Nugraha, Ryan R., Pratiwi, Mutia A., Al-Faizin, Ruli Endepe, Permana, Ardian Budi, Setiawan, Ery, Farianty, Yuli, Komaryani, Kalsum, Thabrany, Hasbullah“…Until recently, in Indonesia, COVID-19 curative package in hospital is paid using a retrospective payment system (claims system) using a per-diem rate. …”
Publicado 2022
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28286por Domen, Andreas, Deben, Christophe, De Pauw, Ines, Hermans, Christophe, Lambrechts, Hilde, Verswyvel, Jasper, Siozopoulou, Vasiliki, Pauwels, Patrick, Demaria, Marco, van de Wiel, Mick, Janssens, Annelies, Hendriks, Jeroen M. H., Van Schil, Paul, Vermorken, Jan B., Vandamme, Timon, Prenen, Hans, Peeters, Marc, Lardon, Filip, Wouters, An“…In a histologically homogenous patient cohort of 100 patients who fulfilled the following criteria: (I) one type of histology, i.e., adenocarcinoma, (II) without known epidermal growth factor receptor (EGFR) mutation, (III) curative (R0) resection and (IV) no neoadjuvant systemic therapy or radiotherapy, the median OS and DFS for patients with a tumoral SS (n=30, 30.0%) compared to patients without a tumoral SS (n=70, 70.0%) was 53 versus 141 months (P=0.005) and 45 versus 55 months (P=0.25), respectively. …”
Publicado 2022
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28287por Quarmyne, Maa-Ohui, Ross, Diana, Sinha, Cynthia, Bakshi, Nitya, Boudreaux, Jeanne, Krishnamurti, Lakshmanan“…BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is a treatment option with curative intent for patients with transfusion dependent thalassemia (TDT) but its application is limited by the lack of suitable donors and acceptability due to the related morbidity/mortality. …”
Publicado 2022
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28288por Sridharan, Swetha, Day, Fiona, Loh, Jasmin, Lynam, James, Smart, Joanne, Holt, Brandan, Mandaliya, Hiren, Bonaventura, Anthony, Kumar, Mahesh, Martin, Jarad“…METHODS: In this phase I trial we enrolled patients with histologically proven squamous cell carcinoma or adenocarcinoma of the esophagus or the gastro-esophageal junction with symptomatic dysphagia from local disease and not for curative treatment. Patients needed to be 18 years or older, have an ECOG performance status of 0–2 and be suitable to receive carboplatin and paclitaxel chemotherapy. …”
Publicado 2022
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28289por Zhang, Tongyue, Wang, Yijun, Xie, Meng, Ji, Xiaoyu, Luo, Xiangyuan, Chen, Xiaoping, Zhang, Bixiang, Liu, Danfei, Feng, Yangyang, Sun, Mengyu, Huang, Wenjie, Xia, Limin“…METHODS: The clinical significance of ETV1 and its target genes in two independent cohorts of HCC patients who underwent curative resection were assessed by Kaplan–Meier analysis and Multivariate Cox proportional hazards model. …”
Publicado 2022
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28290por West, Malcolm, Bates, Andrew, Grimmett, Chloe, Allen, Cait, Green, Richard, Hawkins, Lesley, Moyses, Helen, Leggett, Samantha, Z H Levett, Denny, Rickard, Sally, Varkonyi-Sepp, Judit, Williams, Fran, Wootton, Stephen, Hayes, Matthew, P W Grocott, Micheal, Jack, Sandy“…Background: Surgical resection remains the primary curative treatment for intra-cavity cancer. Low physical fitness and psychological factors such as depression are predictive of post–operative morbidity, mortality and length of hospital stay. …”
Publicado 2022
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28291por Tereshenko, Vlad, Schweizer, Riccardo, Waldner, Matthias, Kim, Bong-Sung, Giovanoli, Pietro, Klein, Holger Jan“…BACKGROUND: Radical excision of debilitating hidradenitis suppurativa lesions is the only curative approach in the advanced stages of the disease. …”
Publicado 2022
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28292por Karageorgou, Margarita, Hughes, David M., Myint, Arthur Sun, Pritchard, D. Mark, Bonnett, Laura J.“…METHODS: Included studies will develop multivariable clinical prediction models which assess response to treatment and overall survival of adult patients who have been diagnosed with any stage of rectal cancer and have received radiotherapy treatment with curative intent. Cohort studies and randomised controlled trials will be included. …”
Publicado 2022
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28293por Reaz, Fardous, Sjobak, Kyrre Ness, Malinen, Eirik, Edin, Nina Frederike Jeppesen, Adli, Erik“…The main objective of radiotherapy is to exploit the curative potential of ionizing radiation while inflicting minimal radiation-induced damage to healthy tissue and sensitive organs. …”
Publicado 2022
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28294por Ye, JingYao, Jiang, Ping, Guan, HuaPeng, Wei, ChuanFu, Li, Sen, Jia, MengLong, Li, NianHu“…This procedure can also improve patients’ pain, neurological function and kyphotic deformity and achieve effects similar to those of traditional methods. With this curative clinical effect, this procedure can be used as an ideal surgical treatment for thoracolumbar fractures in AS patients, especially for elderly patients with underlying diseases and high surgical risk.…”
Publicado 2022
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28295“…The other 4 existing scores are experimental features (CTCF, DNase I, H3K4me3, RRBS) commonly used in deep learning models for off-target activity prediction. For data curation, MNase was aggregated from existing experimental nucleosome occupancy data. …”
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28296“…Sur le plan thérapeutique, la patiente a été mise sous héparinothérapie à dose curative avec relais par anti-vitamine K. L’évolution était favorable avec disparition de la tuméfaction du membre supérieur gauche. …”
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28297“…On the one hand, we present a methodology for creating a well-curated data set for the contextual machine learning application. …”
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28298por dos Santos Vieira, Bruna, Bernabé, César H., Zhang, Shuxin, Abaza, Haitham, Benis, Nirupama, Cámara, Alberto, Cornet, Ronald, Le Cornec, Clémence M. A., ’t Hoen, Peter A. C., Schaefer, Franz, van der Velde, K. Joeri, Swertz, Morris A., Wilkinson, Mark D., Jacobsen, Annika, Roos, Marco“…Ninety-eight FAIRification challenges from 24 ERNs’ registries were collected and categorised into “training” (31), “community” (9), “modelling” (12), “implementation” (26), and “legal” (20). After curating and aggregating highly similar challenges, 41 unique FAIRification challenges remained. …”
Publicado 2022
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28299“…The classification pipeline showcased the ability to exploit relevant plaque morphological features to accurately classify 3 pre-defined stages of atherosclerosis: early fatty streak development (EFS) and advancing atheroma (AA) with a greater than 85% class accuracy CONCLUSIONS: Through the combination of CARS microscopy and computational methods, a powerful classification tool was developed to identify the progression of atherosclerotic plaque in an automated manner. Using a curated dataset, the classification pipeline demonstrated the ability to differentiate between EFS, EF and AA. …”
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28300por Sorayaie Azar, Amir, Babaei Rikan, Samin, Naemi, Amin, Bagherzadeh Mohasefi, Jamshid, Pirnejad, Habibollah, Bagherzadeh Mohasefi, Matin, Wiil, Uffe Kock“…With the help of a clinician, the dataset is curated, and the most relevant features are selected. …”
Publicado 2022
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