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  1. 28501
    “…Specimen label data in natural history collections suggests the presence of this species in large numbers in early July in the avocado growing region of Mexico and, based on notes from former curators, appears to breed in acorns of the Mexican endemic oak species Quercus obtusata. …”
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    On the identity of a U.S. intercepted Conotrachelus Dejean (Coleoptera: Curculionidae) with avocado (Persea americana)
  2. 28502
    “…XLP1 is commonly associated with Epstein–Barr virus (EBV)-associated hemophagocytic lymphohistiocytosis, hypogammaglobulinemia, and/or lymphoma. The only curative treatment for XLP1 is allogeneic hematopoietic cell transplantation. …”
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    Hematopoietic cell transplantation for asymptomatic X-linked lymphoproliferative syndrome type 1
  3. 28503
    “…We applied this method to 42 putative MADS-box core regions in P. abies, from which we assembled 1084 putative transcripts. We manually curated these transcripts to arrive at 933 assembled transcript isoforms of 38 putative MADS-box genes. 152 of these isoforms, which we assign to 28 putative MADS-box genes, were differentially expressed across eight female, male, and vegetative buds. …”
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    Integrative Analysis of Three RNA Sequencing Methods Identifies Mutually Exclusive Exons of MADS-Box Isoforms During Early Bud Development in Picea abies
  4. 28504
    “…He did not receive retreatment due to HCC not amenable for curative treatment. Case 2: 57-year-old male with multiple myeloma, HCV genotype 1a, interferon-experienced without cirrhosis. …”
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    2228. Late Viral Relapse After Direct-Acting Antiviral Treatment in Hepatitis C Virus-Infected Cancer Patients
  5. 28505
    “…Human reads were removed, and remaining sequences aligned to a curated database including >1,000 pathogens. Organisms present above a predefined significance threshold were reported. …”
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    2050. Plasma Next-Generation Sequencing for Pathogen Detection in Pediatric Patients at Risk for Invasive Fungal Infection
  6. 28506
    “…Residual clinical samples were stored for NGS; after filtering human sequences, reads were aligned to a curated pathogen database, and organisms above a predefined threshold were reported (Karius Inc., Redwood City, CA). …”
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    1756. Prediction of Bloodstream Infection Prior to Onset of Symptoms by Plasma Metagenomic Sequencing in Pediatric Patients With Relapsed or Refractory Malignancy (PREDSEQ)
  7. 28507
    “…Human reads were removed and remaining sequences were aligned to a curated database of over 1,000 pathogens. Organisms present above a predefined significance threshold were reported. …”
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    154. Diagnosis and Genotyping of Coxiella burnetii Causing Endocarditis in a Patient With Prosthetic Pulmonary Valve Replacement (PVR) Using Next-Generation Sequencing (NGS) of Plasma
  8. 28508
    “…This study was done to determine whether empiric clindamycin use leads to a curative clinical outcome with respect to adverse effects and correlating D-Test resistance. …”
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    2360. Clinical Outcomes of Clindamycin Use in Skin and Soft-Tissue Infections (SSTIs) in Pediatrics
  9. 28509
    “…CONCLUSIONS: The treatment of VitD in patients with IBD can improve the level of 25(OH)D3 and control the relapse rate of the disease, whose clinical curative effect is more accurate. Thus VitD should be recommended for the treatment of IBD, at least as an adjunctive treatment.…”
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    Efficacy of vitamin D in treatment of inflammatory bowel disease: A meta-analysis
  10. 28510
    “…BACKGROUND: Acute myocardial infarction (MI) remains one of the leading causes of death worldwide with no curative therapy available. Stem cell therapies have been gaining interest as a means to repair the cardiac tissue after MI and prevent the onset of heart failure. …”
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    Bioactive scaffolds in stem-cell-based therapies for cardiac repair: protocol for a meta-analysis of randomized controlled preclinical trials in animal myocardial infarction models
  11. 28511
    “…In parallel, data are manually validated by molecular and clinical curators. Since its creation in 2013, data from 638 FSHD patients have been collected, representing about 21% of the French FSHD population. …”
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    The French National Registry of patients with Facioscapulohumeral muscular dystrophy
  12. 28512
    “…Despite the fact that effective, curative treatments are available with optimal clinical outcomes when diagnosed early, newborn screening does not exist for the majority of these diseases due to the lack of detectable, specific biomarkers or validated methods for population-based screening. …”
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    Rapid Multiplexed Proteomic Screening for Primary Immunodeficiency Disorders From Dried Blood Spots
  13. 28513
    “…Specifically, thirteen co-expressed genes (MAPK8, CYP3A4, PIK3R2, PIK3R4,PRKAB2, G6PC, MAP3K11, FLOT1, PIK3C2G, SHC1, SLC16A2, and RAPGEF1) are also present in the literature curated pathway of ANGPTL8 (WP3915). Moreover, the gene-SNP analysis of highly associated biological processes with ANGPTL8 revealed significant genetic signals associated to Diabetes Mellitus and similar phenotypic traits. …”
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    Biological Pathways Leading From ANGPTL8 to Diabetes Mellitus–A Co-expression Network Based Analysis
  14. 28514
    “…However, this manual curation is inefficient at the data scales required of modern phylogenetics and results in alignments that are not reproducible. …”
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    Fully automated sequence alignment methods are comparable to, and much faster than, traditional methods in large data sets: an example with hepatitis B virus
  15. 28515
    “…CONCLUSIONS: We present, OMeta, a web-based software application that is built on data-driven principles for configuring and customizing data standards, capturing, curating, and sharing metadata. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12859-018-2580-9) contains supplementary material, which is available to authorized users.…”
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    OMeta: an ontology-based, data-driven metadata tracking system
  16. 28516
    “…All 351 acute care hospitals in California at which 1 or more adults underwent curative intent surgery between January 1, 2007, and December 31, 2011, with analyses finalized July 15, 2018, were included. …”
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    Assessment of Between-Hospital Variation in Readmission and Mortality After Cancer Surgical Procedures
  17. 28517
    “…METHODS AND MATERIALS: Patients receiving curative-intent RT and concurrent chemotherapy for EC were identified. …”
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    A Comparison of Grade 4 Lymphopenia With Proton Versus Photon Radiation Therapy for Esophageal Cancer
  18. 28518
    “…Service-specific readiness among FHCs for family planning services was 44.0%, routine immunization was 83.6%, antenatal care was 56.5%, preventive and curative care for children was 44.5%, adolescent health services was 74.2%, tuberculosis services was 53.4%, HIV and STI services was 52.2%, and non-communicable disease services was 51.7%. …”
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    Free and universal access to primary healthcare in Mongolia: the service availability and readiness assessment
  19. 28519
    “…Inclusion criteria for this study were curative intended radiotherapy and availability of pre-treatment and interim 18F-FDG PET. 18F-FDG PET/CT scans were acquired before treatment and after 40 Gray (Gy) of radiotherapy. …”
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    Metabolic parameters of sequential 18F-FDG PET/CT predict overall survival of esophageal cancer patients treated with (chemo-) radiation
  20. 28520
    “…Bisphosphonate treatments are not curative. Under ideal circumstances, osteoblasts would synthesize new matrix to fill in erosion cavities caused by osteoclasts, but this is not what occurs. …”
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    Osteoblasts are “educated” by crosstalk with metastatic breast cancer cells in the bone tumor microenvironment
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