“…Regenerative cell therapies could potentially restore the effective lung microcirculation and provide a curative therapy for PAH. The objective of this systematic review was to compare the efficacy of regenerative cell therapies in preclinical models of PAH. …”
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“…Thus, early-IUGT in macaques produces sustained curative expression related significantly to integrated AAV in the absence of clinical toxicity, supporting its therapeutic potential for early-onset monogenic disorders.…”
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“…Here, we report the curative effect of BMSCs on SM-induced ALI in a mouse model. …”
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“…Methods: We identified EC cases treated with curative intent CRT at our institution from 2007 to 2016. …”
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“…PURPOSE: Concurrent chemoradiation (CCRT) is the standard curative treatment of anal canal cancer (ACC). The role of a brachytherapy (BRT) boost in this setting is still debated. …”
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“…There have been no multicentre trials investigating this curative treatment concept in elderly and fit PCNSL patients so far. …”
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“…We performed gene set enrichment analyses using curated databases and findings from prior COPD studies to provide biological and disease relevance. …”
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“…METHODS: We searched MEDLINE/PubMed (1946 to 2018, on July 26, 2018) and Embase (from 1974 to 2018, on July 26, 2018) for randomized controlled trials (RCTs) and cohort studies evaluating diverse integrated models’ effects on sustained virological response (SVR), HIV suppression, HBV curation or suppression, completion of TB treatment regimen among people with SUD. …”
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“…IMPORTANCE: Axicabtagene ciloleucel, a chimeric antigen receptor T-cell therapy, represents a new and potentially curative treatment option for B-cell lymphoma. It is expected to have long-term survival benefits; however, long-term survival data are limited. …”
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“…Patients with risk factors should be monitored closely after curative surgery.…”
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“…BACKGROUND: Bipartite combined oesophageal tumours are an exceedingly rare entity and much less is known about the natural history of these tumours following curative surgery. The authors present a case of a bipartite combined oesophageal tumour comprising of sarcomatoid carcinoma and small cell carcinoma with early postoperative recurrence. …”
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“…RESULTS: Therefore, we first performed a comparative genomic analysis of bile acid deconjugation and biotransformation pathways in 693 human gut microbial genomes and expanded 232 curated genome-scale microbial metabolic reconstructions with the corresponding reactions (available at https://vmh.life). …”
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“…BACKGROUND: Blended cognitive behaviour therapy (bCBT) is an effective treatment for fear of cancer recurrence (FCR) in curatively-treated breast, colorectal and prostate cancer survivors with high FCR. …”
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“…Women of reproductive age with primary hyperparathyroidism need to be informed of the risks and complications associated with primary hyperparathyroidism in pregnancy and pregnancy should be deferred and or avoided until curative surgery has been performed and calcium levels have normalised.…”
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“…These assemblies and the manually curated human protein sequences from UniProtKB/Swiss-Prot were used in a reciprocal BLAST search to identify best matching hits. …”
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“…Why do patients choose for this treatment, while the treatment success rate is limited and curation cannot be achieved? And second, once chosen, what conditions would patients like to satisfy and how do they experience the treatment? …”
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“…RESULTS: Data-independent mass spectrometry enabled the unbiased quantitative characterization of 841 significant MWCNT-responses within an enriched peptide fraction, with 567 of these factors demonstrating significant correlation across animal-paired bronchoalveolar lavage and serum biofluids. A database search curated for known matrix protease substrates and predicted signaling motifs enabled identification of 73 MWCNT-responsive peptides, which were significantly associated with an abnormal cardiovascular phenotype, extracellular matrix organization, immune-inflammatory processes, cell receptor signaling, and a MWCNT-altered serum exosome population. …”
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“…Background: Allogeneic hematopoietic stem cell transplantation (HSCT) is a potentially curative therapy for a variety of malignant and non-malignant disorders. …”
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“…We analyzed WES data for 20,341 T2D cases and 23,981 controls with additional lipid, body mass index (BMI), and blood pressure (BP) measurements. Eight sets of curated genes were either (a) targeted by a medication for T2D (8 genes), hypercholesterolemia (13 genes), obesity (6 genes), or high BP (41 genes); or (b) targeted by a medication with a known side effect of T2D (8 genes), hypercholesterolemia (54 genes), obesity (230 genes), or elevated BP (126 genes). …”
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“…The treatment of choice for well-circumscribed pituitary adenomas is transphenoidal surgery, which may be curative (2). References 1.Colao A, Pivonello R, Di Somma C, TauchmanovàL, Savastano S, Lombardi G. …”
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