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28541“…Medical therapy has been described for patients who do not undergo surgery but is generally not curative. Although we present great improvement in our patient with somatostatin treatment as primary therapy, remission was short lived, and patient will need surgical resection to achieve cure from her disease. …”
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28542por Wang, Quan, Guo, Bo-Yang, Zhao, Qing-Chuan, Yan, Zun-Dong, Shang, Li-Feng, Yu, Juan, Ji, Gang“…Currently, surgery is the only curative treatment for gastric cancer; however, there is an increasing trend toward laparoscopic radical gastrectomy. …”
Publicado 2019
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28543por Murray, Nigel P, Aedo, Sócrates, Villalon, Ricardo, López, Marco Antonio, Minzer, Simona, Muñoz, Lorena, Orrego, Shenda, Contreras, Luis, Arzeno, Lucas, Guzman, Eghon“…PATIENTS AND METHODS: One month of curative surgery and 1 month after completing six cycles of FOLFOX chemotherapy blood and bone marrow samples were taken to detect CTCs and mM using immunocytochemistry with anti-carcino-embryonic antigen (CEA). …”
Publicado 2019
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28544por Okada, Kazuaki, Sato, Akira, Hiramoto, Akiko, Isogawa, Rena, Kurosaki, Yuji, Higaki, Kazutaka, Miyoshi, Shin-Ichi, Chang, Kyung-Soo, Kim, Hye-Sook“…As an endoperoxide structure in the body, the compound shows high antimalarial activity and curative effects. We performed a pharmacokinetic (PK) analysis of N-251 under various conditions using mice to understand the inhibitory effect of N-251 in parasite-infected mice. …”
Publicado 2019
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28545por Wei, Cuibai, Qin, Qi, Chen, Fei, Zhou, Aihong, Wang, Fen, Zuo, Xiumei, Chen, Rong, Lyu, Jihui, Jia, Jianping“…These findings suggest that clinicians should be aware of adult-onset forms of VWMD as well as its typical magnetic resonance imaging (MRI) and clinical characteristics although this pathology is usually recognized as a pediatric disorder. No curative treatment is presently available, and thus early recognition is important to prevent triggering events and to allow for genetic counseling. …”
Publicado 2019
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28546por Ahn, Seong Beom, Sharma, Samridhi, Mohamedali, Abidali, Mahboob, Sadia, Redmond, William J., Pascovici, Dana, Wu, Jemma X., Zaw, Thiri, Adhikari, Subash, Vaibhav, Vineet, Nice, Edouard C., Baker, Mark S.“…BACKGROUND: One of the most significant challenges in colorectal cancer (CRC) management is the use of compliant early stage population-based diagnostic tests as adjuncts to confirmatory colonoscopy. Despite the near curative nature of early clinical stage surgical resection, mortality remains unacceptably high—as the majority of patients diagnosed by faecal haemoglobin followed by colonoscopy occur at latter stages. …”
Publicado 2019
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28547por Curtis, N. J., Conti, J. A., Dalton, R., Rockall, T. A., Allison, A. S., Ockrim, J. B., Jourdan, I. C., Torkington, J., Phillips, S., Allison, J., Hanna, G. B., Francis, N. K.“…Patients requiring elective laparoscopic TME with curative intent were centrally randomised (1:1) to 2D or 3D using Karl Storz IMAGE1 S D3-Link™ and 10-mm TIPCAM®1S 3D passive polarising laparoscopic systems. …”
Publicado 2019
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28548por Hao, Emmanuel II Uy, Rho, Seoung Yoon, Hwang, Ho Kyoung, Chung, Jae Uk, Lee, Woo Jung, Yoon, Dong Sup, Kang, Chang Moo“…METHODS: Data from 2005 to 2017 at Severance Hospital of the Yonsei University Health systems in Seoul, South Korea, were retrospectively collected for 25 patients who were diagnosed with SPN of the uncinate, head, and neck of the pancreas and who underwent curative resection. Three groups of patients were considered, depending on the year of surgery, in order to determine trends in the surgical management of SPN. …”
Publicado 2019
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28549por Ingham, Anna Cäcilia, Kielsen, Katrine, Cilieborg, Malene Skovsted, Lund, Ole, Holmes, Susan, Aarestrup, Frank M., Müller, Klaus Gottlob, Pamp, Sünje Johanna“…HSCT is employed as curative immunotherapy for a number of non-malignant and malignant hematologic conditions, including cancers such as acute lymphoblastic leukemia. …”
Publicado 2019
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28550por Angell, Trevor E., Wirth, Lori J., Cabanillas, Maria E., Shindo, Maisie L., Cibas, Edmund S., Babiarz, Joshua E., Hao, Yangyang, Kim, Su Yeon, Walsh, P. Sean, Huang, Jing, Kloos, Richard T., Kennedy, Giulia C., Waguespack, Steven G.“…Introduction: The Afirma® Xpression Atlas (XA) detects gene variants and fusions in thyroid nodule FNA samples from a curated panel of 511 genes using whole-transcriptome RNA-sequencing. …”
Publicado 2019
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28551por Bidarra, David, Constâncio, Vera, Barros-Silva, Daniela, Ramalho-Carvalho, João, Moreira-Barbosa, Catarina, Antunes, Luís, Maurício, Joaquina, Oliveira, Jorge, Henrique, Rui, Jerónimo, Carmen“…Herein, we evaluated the screening and prognostic biomarker potential of two onco-microRNAs (miR-182-5p and miR-375-3p) in liquid biopsies (plasma) of PCa patients with clinically localized disease undergoing curative-intent treatment. A first cohort of 98 PCa and 15 normal prostates were used to assess PCa-specificity of miR-182-5p in tissues. …”
Publicado 2019
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28552por de Freitas, Laura Bainy Rodrigues, Longo, Larisse, Santos, Deivid, Grivicich, Ivana, Álvares-da-Silva, Mário Reis“…CONCLUSION: In a Western population, the general agreement between the two systems was 80.0%, although in BCLC-B cases the agreement was low, suggesting that some individuals could be candidates for the curative treatment recommended by the HKLC. The authors suggest that the BCLC system should be routinely employed, although for BCLC-B cases it should be associated with the HKLC system.…”
Publicado 2019
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28553por Yu, Yiyi, Fang, Yong, Shen, Zhenbin, Wang, Yan, Yan, Min, Cao, Hui, Liu, Yingbin, Wang, Xuefei, Cui, Yuehong, Liu, Fenglin, Chen, Weidong, Li, Wei, Li, Qian, Jiang, Huiqin, Sun, Yihong, Liu, Tianshu“…Each 3‐week cycle comprised capecitabine 1,000 mg/m(2) twice daily on days 1–14 and oxaliplatin 130 mg/m(2) on day 1. Curative D2 gastrectomy was scheduled 2–4 weeks after the last preoperative cycle. …”
Publicado 2019
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28554por Peng, Jianhong, Li, Weihao, Zhang, Rongxin, Lin, Junzhong, Tang, Jinghua, Wen, Yongshan, Lu, Zhenhai, Wu, Xiaojun, Pan, Zhizhong“…METHODS: We retrospectively analyzed 330 eligible patients with stage III colon cancer who underwent curative tumor resection followed by mXELOX, standard XELOX or unfinished XELOX adjuvant chemotherapy between December 2007 and April 2015. …”
Publicado 2019
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28555por Malek, Alexandre, Fares, Johny, Khalil, Melissa, Hachem, Ray Y, Chaftari, Anne-Marie, Jiang, Ying, Kontoyiannis, Dimitrios P, Fossella, Frank, Chaftari, Patrick, Mulanovich, Victor E, Viola, George, Raad, Issam I“…BACKGROUND: Immune checkpoint inhibitors (ICI) therapy has ushered cancer treatment into a potentially curative era. However, infectious complications remain largely unknown and the few studies that described infectious complications associated with ICI had no comparative control groups. …”
Publicado 2019
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28556por Handel, Andrew S, Ho, Carine, Hollemon, Desiree D, Hong, David K, Beneri, Christy“…Human reads were removed and remaining sequences were aligned to a curated microbial database. Only mcfDNA testing was performed at follow-up visits. …”
Publicado 2019
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28557por Centeno, Fernando H, Ahmed, Asim A, Hong, David K, Dalai, Sudeb, Woc-Colburn, Laila“…After mcfDNA is extracted and NGS performed, human sequences are removed and remaining sequences are aligned to a curated pathogen database of >1,000 organisms. Organisms present above a statistical threshold are reported. …”
Publicado 2019
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28558636. Genome Epidemiology of Carbapenem-Resistant Acinetobacter baumannii (CRAb) in the United Statespor Iovleva, Alina, Mustapha, Mustapha, Cober, Eric, Richter, Sandra S, Arias, Cesar A, Jacob, Jesse T, Salata, Robert, Satlin, Michael J, Wong, Darren, Bonomo, Robert A, van Duin, David, Doi, Yohei“…Sequence types (STs) were identified using the Pasteur Institute MLST scheme. β-Lactamase genes were identified by ResFinder and manually curated. RESULTS: The 131 isolates belonged to 10 different ST types, including 8 known and 2 novel ones. …”
Publicado 2019
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28559por D'Souza, Julia C., Sultan, Laith R., Hunt, Stephen J., Gade, Terence P., Karmacharya, Mrigendra B., Schultz, Susan M., Brice, Angela K., Wood, Andrew K. W., Sehgal, Chandra M.“…Background and Objective: Hepatocellular carcinoma (HCC) is the most common primary liver malignancy, and its current management relies heavily on locoregional therapy for curative therapy, bridge to transplant, and palliative therapy. …”
Publicado 2019
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28560“…However, acute and late toxicities of IR in normal tissues are still important biological barriers to successful RT: While curative RT may not be tolerable, sub-optimal tolerable RT doses will lead to fatal outcomes by local recurrence or metastatic disease, even when accepting adverse normal tissue effects that decrease the quality of life of irradiated cancer patients. …”
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