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29141“…Available at: http://www.yeastgenome.org/download-data/curation) with the functions of Gene Ontology terms is available at: (see Appendix for more details about the demo)http://ecesrvr.kustar.ac.ae:8080/PPFBM/.…”
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29142“…METHODS: We retrospectively reviewed 72 consecutive patients with (18)F-FDG PET/CT-detected widespread pelvic, para-aortic and/or supraclavicular lymph nodes treated with curative-intent PET-guided cisplatin-based extended-field dose-escalating intensity-modulated radiotherapy (IMRT) and adaptive high-dose-rate intracavitary 3D-brachytherapy between 2002 and 2010. …”
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29143por Herrera, Fernanda G., Breuneval, Thomas, Prior, John O., Bourhis, Jean, Ozsahin, Mahmut“…METHODS: Thirty-eight patients treated with standard curative doses of chemo-radiotherapy (CRT) underwent pre- and post-therapy [(18)F]FDG-PET/CT. [(18)F]FDG-PET/CT parameters including mean tumor standardized uptake values (SUV), metabolic tumor volume (MTV) and tumor glycolytic volume (TGV) were measured before the start of CRT. …”
Publicado 2016
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29144por Arians, Nathalie, Foerster, Robert, Rom, Joachim, Uhl, Matthias, Roeder, Falk, Debus, Jürgen, Lindel, Katja“…CONCLUSION: The radical procedure of resection combined with IOERT seems to be a valid curative treatment option for patients with recurrent endometrial carcinoma with 5-year survival rates of 50 %. …”
Publicado 2016
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29145por Sarntivijai, Sirarat, Vasant, Drashtti, Jupp, Simon, Saunders, Gary, Bento, A. Patrícia, Gonzalez, Daniel, Betts, Joanna, Hasan, Samiul, Koscielny, Gautier, Dunham, Ian, Parkinson, Helen, Malone, James“…METHODS: Semantic mapping uses a combination of custom scripting, our annotation tool ‘Zooma’, and expert curation. Disease-phenotype associations were generated using literature mining on Europe PubMed Central abstracts, which were manually verified by experts for validity. …”
Publicado 2016
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29146por Gemici, Cengiz, Yetmen, Ozlem, Yaprak, Gokhan, Ozden, Sevgi, Tepetam, Huseyin, Ozyurt, Hazan, Mayadagli, Alpaslan“…The aim of cancer treatment was palliative for metastatic patients (36 out of 63), or adjuvant or curative for patients with localized disease (27 out of 63). …”
Publicado 2016
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29147por Chen, Jin-Hua, Yen, Yu-Chun, Liu, Shing-Hwa, Yuan, Sheng-Po, Wu, Li-Li, Lee, Fei-Peng, Lin, Kuan-Chou, Lai, Ming-Tang, Wu, Chia-Che, Chen, Tsung-Ming, Chang, Chia-Lun, Chow, Jyh-Ming, Ding, Yi-Fang, Lin, Ming-Chin, Wu, Szu-Yuan“…The exclusion criteria were a cancer history before head and neck cancer diagnosis, distant metastasis, AJCC clinical cancer stage I or II, receipt of platinum and docetaxel before radiotherapy, an age <20 years, missing sex data, docetaxel use during or after RT, induction CT for >8 weeks before RT, induction CT alone before RT, cetuximab use, adjuvant CT within 90 days after RT completion, an RT dose <7000 cGy, curative head and neck cancer surgery before RT, nasopharyngeal cancer, in situ carcinoma, sarcoma, and head and neck cancer recurrence. …”
Publicado 2016
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29148por Ruggeri, Annalisa, Battipaglia, Giorgia, Labopin, Myriam, Ehninger, Gerhard, Beelen, Dietrich, Tischer, Johanna, Ganser, Arnold, Schwerdtfeger, Rainer, Glass, Bertram, Finke, Jurgen, Michallet, Mauricette, Stelljes, Matthias, Jindra, Pavel, Arnold, Renate, Kröger, Nicolaus, Mohty, Mohamad, Nagler, Arnon“…BACKGROUND: Allogeneic stem cell transplantation is the only curative option for patients with acute myeloid leukemia (AML) experiencing relapse. …”
Publicado 2016
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29149por Hasebrook, Joachim Paul, Hinkelmann, Jürgen, Volkert, Thomas, Rodde, Sibyll, Hahnenkamp, Klaus“…The situation will become more difficult because, on the whole, patients are becoming older and sicker and because specialist physicians are able to find more attractive working conditions in smaller hospitals, abroad, or outside of curative medicine. OBJECTIVE: In order to retain sufficient qualified employees, major improvements in quality are required in terms of working and training conditions. …”
Publicado 2016
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29150“…METHODS: A retrospective review was performed of a prospectively-maintained database of adult patients who underwent esophagectomy or gastrectomy (subtotal or total) for cancer with curative intent, from January 2001 to June 2014. Patient demographics, the approach to esophagectomy, the extent of gastrectomy, FJT placement and utilization at discharge, administration of parenteral nutrition (PN), and complications were evaluated. …”
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29151“…The control group was given routine treatment while the study group was given routine treatment combined with intravenous infusion of salvianolate (200 mg administered once at 24 h before operation, once/day after operation, 1 week later, the curative effect was observed). The changes in levels of hemodynamic indexes [fibrinogen (FIB), platelet aggregation rate (PAG), plasma viscosity, packed-cell volume (PCV)], oxidative stress indexes [superoxide dismutase (SOD), glutathione peroxidase (GSH Px)], cardiac function indexes [left ventricular ejection fraction (LVEF), cardiac output (CO)], related biochemical indexes [high-sensitivity C-reactive protein (hs-CRP), N-terminal pro brain natriuretic peptide (NT proBNP)] and plasma IMD/ADM2 in the two groups at 24 h pre-operation and the 8th day postoperation were analyzed. …”
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29152por Ishikawa, Tetsuya“…For final confirmation, mutated genotypes were manually curated using the Integrative Genomics Viewer. RESULTS: In eight of the ten iPSC lines, one or two non-synonymous SNVs in EIF2AK2, TTN, ULK4, TSSK1B, FLT4, STK19, STK31, TRRAP, WNK1, PLK1 or PIK3R5 were identified as novel SNVs and were not identical to the genotypes found in the cancer and non-cancerous tissues. …”
Publicado 2017
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29153por Fu, Xiu-Tao, Shi, Ying-Hong, Zhou, Jian, Peng, Yuan-Fei, Liu, Wei-Ren, Shi, Guo-Ming, Gao, Qiang, Wang, Xiao-Ying, Song, Kang, Fan, Jia, Ding, Zhen-Bin“…METHODS: A retrospective analysis of the clinical data of 39 HCC patients with HBV-HCV coinfection who underwent curative hepatectomy between 2001 and 2011 was performed. …”
Publicado 2017
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29154por Rappaport, Noa, Fishilevich, Simon, Nudel, Ron, Twik, Michal, Belinky, Frida, Plaschkes, Inbar, Stein, Tsippi Iny, Cohen, Dana, Oz-Levi, Danit, Safran, Marilyn, Lancet, Doron“…GeneCards and MalaCards delineate and share a multi-tiered, scored gene-disease network, with stringency levels, including the definition of elite status—high quality gene-disease pairs, coming from manually curated trustworthy sources, that includes 4500 genes for 8000 diseases. …”
Publicado 2017
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29155por Benamu, Esther, Gajurel, Kiran, Anderson, Jill N, Seng, Hon, Hollemon, Desiree, Hong, David, Blawkamp, Timothy A, Kertesz, Mickey, Ishak, Heather, Bollyky, Paul L, Medeiros, Bruno C, Coutre, Steven, Montoya, Jose G, Deresinski, Stan“…After removing human reads, remaining sequences were aligned to a curated pathogen database. Organisms present at a significance- level above a predefined threshold were reported. …”
Publicado 2017
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29156“…Because expanding and curating such a resource is a costly process, it is beneficial and even necessary to identify terms important for patient EHR comprehension first. …”
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29157“…RESULTS: Based on manual review and curation of scientific publications a catalog comprising 140 human genes involved in response to TBEV infection was developed. …”
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29158“…Then, we compared our workflow’s performance with another model recently developed by Metushi et al., which proposed seven in silico HLA-B*57:01 actives, but were later found to be experimentally inactive. METHODS: After curation, there were over 6000 approved and experimental drugs remaining in DrugBank for docking using Schrodinger’s GLIDE SP and XP scoring functions. …”
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29159por Jones, Darryl R., Thomas, Dallas, Alger, Nicholas, Ghavidel, Ata, Inglis, G. Douglas, Abbott, D. Wade“…In addition, these trees can be integrated with user-defined datasets (e.g., genomics, metagenomics, and transcriptomics) to inform experimental characterization of new CAZymes or CBMs not currently curated, and for researchers to compare differential sequence patterns between entire CAZomes. …”
Publicado 2018
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29160“…PATIENTS AND METHODS: A total of 119 patients with secondary LNM after resection of ESCC were recruited and received curative RT only or CRT. The enrolled patients were grouped according to the median values of NLR, PLR, V(LN), and D(LN). …”
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