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29281por Urso, Luca, Rocca, Giovanni Christian, Borgia, Francesca, Lancia, Federica, Malorgio, Antonio, Gagliano, Mauro, Zanetto, Mauro, Uccelli, Licia, Cittanti, Corrado, Ippolito, Carmelo, Evangelista, Laura, Bartolomei, Mirco“…Moreover, TLCKA of the primary lesion looks a promising parameter for predicting recurrence after curative therapy.…”
Publicado 2022
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29282“…Early diagnosis provides a good chance of complete surgical removal as the only curative treatment. Presentation: No date and time listed…”
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29283por Gosmanov, Aidar, Green, Maria, Gerges, Antoni Kafrouni, Roy, Mary, Ziganshina, Anna“…This decision was taken with the consideration that this would likely not be curative but intended to improve the course of her metabolic conditions. …”
Publicado 2022
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29284“…Google’s software development kit was used to securely capture data about the number of downloads, location of downloads, number of app sessions, frequency and duration of app sessions, time between app sessions, and user retention, allowing for examination of which app’s tools were viewed and for how long, including Information (psychoeducation), Test (self-monitoring using the Patient Health Questionnaire [PHQ-9]), Thought Diary (targeting negative cognitions), Activities (behavioral activation), Videos (curated from YouTube), and Safety Plan (safety plan development and links to quickly access crisis management resources). …”
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29285por Hu, Huan-Fu, Wang, Zheng, Tang, Wen-Li, Fu, Xue-Ming, Kong, Xiang-Jun, Qiu, Ying-Kun, Xi, Sheng-Yan“…Background: Sophora flavescens aiton (SFA) and its main bioactive metabolite matrine are widely used in traditional Chinese medicine (TCM) preparations and have achieved good curative effects for the treatment of various tumors. …”
Publicado 2022
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29286por Haraoui, Louis-Patrick, Grenier, Frédéric, Heynemand, Félix, Lévesque, Simon, Sullivan, Richard, Landecker, Hannah L, Higgins, Paul G, Rodrigue, Sébastien“…METHODS: Strains from 3 archives underwent whole-genome sequencing (Illumina NovaSeq on all, MinION on a subset) and computational analyses: assembly (Unicycler), annotation (prokka), identification (Kraken, 16S rRNA), search for carbapenemases (ResFinder, BLDB curation). Figures were generated in Inkscape, plasmid alignment on AliTV. …”
Publicado 2022
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29287por Hughes, Daniel Johnathan, Kapiris, Matthaios, Podvez Nevajda, Andreja, McGrath, Harriet, Stavraka, Chara, Ahmad, Shahreen, Taylor, Benjamin, Cook, Gary J. R., Ghosh, Sharmistha, Josephs, Debra, Pintus, Elias, Gennatas, Spyridon, Bille, Andrea, Ryanna, Kimuli, Santis, George, Montes, Ana, Van Hemelrijck, Mieke, Karapanagiotou, Eleni, Smith, Daniel, Spicer, James, Georgiou, Alexandros“…Only 31% (n = 76) had treatment with curative intent. In patients who presented or developed metastatic non-squamous NSCLC (n = 179), EGFR mutation status was known in 88% (n = 157) and mutation present in 19% (n = 34), ALK was known in 66% (n = 118) with a translocation in 10% (n = 18), ROS1 status was known in 57% (n = 102) with a translocation in 4% (n = 8), and KRAS status was known in 66% (n = 119) with a mutation in 12% (n = 22). …”
Publicado 2022
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29288“…Overexpression of TAK1 was revealed to abolish the curative effects of miR-143-3p on insulin secretion, cell viability and inflammatory response in HG-treated MIN6 cells. …”
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29289por Bailly-Caillé, Barbara, Kottler, Diane, Morello, Rémy, Lecornu, Marie, Kao, William, Meyer, Emmanuel, Dompmartin, Anne, L’Orphelin, Jean-Matthieu“…ABSTRACT: Background: Cemiplimab is a monoclonal antibody targeting the PD-1, and phase II trials have shown its efficacy in the treatment of advanced cutaneous squamous cell carcinoma in patients who are not candidates for curative surgery or radiation therapy as a first- or later-line treatment. …”
Publicado 2023
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29290por Topal, Halit, Aerts, Raymond, Laenen, Annouschka, Collignon, André, Jaekers, Joris, Geers, Joachim, Topal, Baki“…OBJECTIVE: To study long-term survival after MIPS and OPS with curative intent among patients with pancreatic adenocarcinoma. …”
Publicado 2022
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29291por Averbuch, Itamar, Salman, Saeed, Shtamper, Noa, Doweck, Ilana, Popovtzer, Aron, Markel, Gal, Hendler, Daniel, Finkel, Inbar, Moore, Assaf, Fenig, Eyal, Taha, Tarek, Mhameed, Kamel, Kurman, Noga, Billan, Salem“…Many of the affected patients are elderly with comorbidities who are not candidates for standard-of-care curative-intent treatment with surgery and/or radio-/chemotherapy. …”
Publicado 2023
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29292por Braun, Rüdiger, Lapshyna, Olha, Watzelt, Jessica, Drenckhan, Maren, Künstner, Axel, Färber, Benedikt, Hael, Ahmed Ahmed Mohammed, Bolm, Louisa, Honselmann, Kim Christin, Konukiewitz, Björn, Castven, Darko, Spielmann, Malte, Gorantla, Sivahari Prasad, Busch, Hauke, Marquardt, Jens-Uwe, Keck, Tobias, Wellner, Ulrich Friedrich, Ungefroren, Hendrik“…Although surgical resection is the only curative treatment option, multimodal treatment is of the utmost importance, as only about 20% of tumors are primarily resectable at the time of diagnosis. …”
Publicado 2023
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29293por Zhong, Wanru, Li, Yihua, Zhong, Haixiang, Cheng, Yuanyuan, Chen, Qi, Zhao, Xinjun, Liu, Zhongqiu, Li, Rong, Zhang, Rong“…Background: Qiweiqiangxin І granules (QWQX І) is a traditional Chinese medicine preparation based on the basic theory of traditional Chinese medicine, which produces a good curative effect in treating chronic heart failure (CHF). …”
Publicado 2023
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29294por Molina, George, Ruan, Mengyuan, Lipsitz, Stuart R., Iyer, Hari S., Hassett, Michael J., Brindle, Mary E., Trinh, Quoc-Dien“…IMPORTANCE: Among patients with colorectal liver metastasis (CRLM) who are eligible for curative-intent liver surgical resection, only half undergo liver metastasectomy. …”
Publicado 2023
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29295por Xin, Hao-Yang, Sun, Rong-Qi, Zou, Ji-Xue, Wang, Peng-Cheng, Wang, Jia-Yin, Ye, Yu-Hang, Liu, Kai-Xuan, Hu, Zhi-Qiang, Zhou, Zheng-Jun, Fan, Jia, Zhou, Jian, Zhou, Shao-Lai“…DESIGN, SETTING, AND PARTICIPANTS: In this cohort study, 1175 patients who underwent curative resection for ICC from January 1, 2009, through December 31, 2017, were evaluated at a single hospital in China. …”
Publicado 2023
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29296“…IMAGE: [Image: see text] CONCLUSION(S): A transanal endoscopic cooperative surgery combining ESD and TAMIS was safe and effective, combining the advantages of each procedural technique, in providing curative en-bloc resection of a recurrent large near-circumferential low rectal tubulovillous adenoma with HGD involving the dentate line. …”
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29297por Baur, Rebecca, Karl, Franziska, Böttcher-Loschinski, Romy, Stoll, Andrej, Völkl, Simon, Gießl, Andreas, Flamann, Cindy, Bruns, Heiko, Schlötzer-Schrehardt, Ursula, Böttcher, Martin, Schewe, Denis M, Fischer, Thomas, Jitschin, Regina, Mackensen, Andreas, Mougiakakos, Dimitrios“…Allogeneic hematopoietic stem cell transplantation (allo-HSCT) represents the only curative treatment option for a number of hemato-oncological disorders. …”
Publicado 2023
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29298por Ge, Pu, Zhang, Zi-Wei, Zhang, Jin-Zi, Lyu, Ke, Niu, Yu-Yao, Tong, Yu-Ting, Xiong, Ping, Ling, Rong, Li, Qi-Yu, Yu, Wen-Li, Min, He-Wei, Deng, Yu-Qian, Wang, Yu-Jia, Sun, Xiao-Nan, Sun, Xin-Ying, Yu, Lian, Wu, Yi-Bo“…The residents in the east, central and western regions who consider safety is 63.5%, 61.5%, and 66.8% respectively. The proportion of curative effect was 60.2%, 55.7%, and 61.4% respectively. …”
Publicado 2023
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29299por Daskalakis, Kosmas, Wedin, Maria, Tsoli, Marina, Kogut, Angelika, Srirajaskanthan, Raj, Sarras, Konstantinos, Kattiparambil, Sajith, Giovos, George, Weickert, Martin O., Kos‐Kudla, Beata, Kaltsas, Gregory“…We aimed to assess the prognostic impact of tumor‐ and patient‐related parameters in patients with stage I–III small intestinal neuroendocrine tumors (SI‐NETs), who underwent locoregional resective surgery (LRS) with curative intent. We included 229 patients with stage I–III SI‐NETs diagnosed from June 15, 1993, through March 8, 2021, identified using the SI‐NET databases from five European referral centers. …”
Publicado 2022
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29300por Batatinha, Helena, Diak, Douglass M., Niemiro, Grace M., Baker, Forrest L., Smith, Kyle A., Zúñiga, Tiffany M., Mylabathula, Preteesh L., Seckeler, Michael D., Lau, Branden, LaVoy, Emily C., Gustafson, Michael P., Katsanis, Emmanuel, Simpson, Richard J.“…Flow cytometry and single-cell RNA sequencing was performed to identify phenotypic and transcriptomic differences between resting and exercise-mobilized cells using a targeted gene expression panel curated for human immunology. PBMCs were injected into the tail vein of xenogeneic NSG-IL-15 mice and subsequently challenged with a luciferase tagged chronic myelogenous leukemia cell line (K562). …”
Publicado 2023
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