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  1. 29481
    “…BACKGROUND: Intrauterine hematopoietic stem cell transplantation (IUT), potentially curative in congenital haematological disease, is often inhibited by deleterious immune responses to donor cells resulting in subtherapeutic donor cell chimerism (DCC). …”
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    Maternal dendritic cells influence fetal allograft response following murine in-utero hematopoietic stem cell transplantation
  2. 29482
    “…METHODS: 157 GC patients (pathological stages I 82, II 34, and III 41) who underwent surgery with curative intent were analyzed. VI was graded in pathological examination by elastica van Gieson staining based on the number of VIs per glass slide as follows: v0, 0; v1, 1−3; v2, 4−6; and v3, ≥ 7. …”
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    Risk stratification for predicting postoperative recurrence of gastric cancer by grade of venous invasion
  3. 29483
    “…Tumor specimens of PDAC patients were immune-stained of KLF10 to correlate with local recurrence after curative resection. Conditional overexpressing KLF10 in MiaPaCa and stably depleting KLF10 in Panc-1 (Panc-1-pLKO-shKLF10) cells were established for evaluating sphere formation, stem cell markers expression and tumor growth. …”
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    Krüppel-like factor 10 modulates stem cell phenotypes of pancreatic adenocarcinoma by transcriptionally regulating notch receptors
  4. 29484
    “…Here, we take advantage of the recent increase in mollusc genomic resources and adopt an automated TE annotation pipeline combined with a phylogenetic tree-based classification, as well as extensive manual curation efforts, to characterize TE repertories across 27 bivalve genomes with a particular emphasis on DDE/D class II elements, long interspersed nuclear elements (LINEs), and their evolutionary dynamics. …”
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    Multiple and diversified transposon lineages contribute to early and recent bivalve genome evolution
  5. 29485
    “…The aim of the present study was to determine whether elevated pre-operative and post-operative CEA values are useful prognostic biomarkers for patients with stage I-III colon cancer who underwent surgery with curative intent. METHODS: We conducted a retrospective study in patients with histologically confirmed stage I-III primary colonic adenocarcinoma who underwent radical surgical resection at Mexico’s National Cancer Institute, between January 2008 and January 2020. …”
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    Persistent high levels of carcinoembryonic antigen after tumor resection are associated with poorer survival outcomes in patients with resected colon cancer
  6. 29486
    “…BACKGROUND: Artemisinin-based combinations therapy (ACT) is the current frontline curative therapy for uncomplicated malaria in Burkina Faso. …”
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    Plasmodium falciparum drug resistance-associated mutations in isolates from children living in endemic areas of Burkina Faso
  7. 29487
    “…High CD73 expression in colorectal cancer liver metastasis (CRLM) resected with curative intent is associated with early recurrence and shorter patient survival. …”
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    Radiomics using computed tomography to predict CD73 expression and prognosis of colorectal cancer liver metastases
  8. 29488
    “…METHODS: A total of 299 patients underwent CRC surgery with curative intent between January 2013 and December 2017. …”
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    The five-item modified frailty index predicts long-term outcomes in elderly patients undergoing colorectal cancer surgery
  9. 29489
    “…Accumulated medical knowledge is due to the extensive length of occupation by Bulang People, considered the earliest inhabitants of Xishuangbanna; this has resulted in the development of various traditional treatment methods with local characteristics and unique curative effects. Therefore, there is exceeding value in exploring the medical knowledge of Bulang. …”
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    Ethnobotanical study on medicinal plants used by Bulang people in Yunnan, China
  10. 29490
    “…For treatment resistance, a previously curated phenotype based on general practitioner (GP) records and prescription data was employed. …”
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    Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study
  11. 29491
    “…However, most of the studies were limited to the initial candidate identification, which needs to be further validated and have assays developed for clinical use. Here we curate these studies to help prioritize biomarker candidates for validation studies and to obtain a broader view of processes regulated during disease development. …”
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    Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response
  12. 29492
    “…METHODS: Proximity extension assay was applied to analyse 92 immune-associated proteins in longitudinal serum samples from 75 patients, 18 treated with curative and 57 with palliative intent. HRQoL data were available from all patients at baseline (BL), from 41 patients at three months, and from 23 patients at six months. …”
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    Trajectories of immune-related serum proteins and quality of life in patients with pancreatic and other periampullary cancer: the CHAMP study
  13. 29493
    “…We will include people aged 18 years and older who have been registered in general practices in the Research and Surveillance Centre network and have a record of CLD between January 1, 2012, and December 31, 2022, including those with alcohol-related liver disease, chronic hepatitis B, chronic hepatitis C, nonalcohol fatty liver disease, Wilson disease, hemochromatosis, and autoimmune hepatitis. We will carefully curate variables using the Systematized Nomenclature of Medicine Clinical Terms. …”
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    Hepatitis A Vaccination Coverage Among People With Chronic Liver Disease in England (HEALD): Protocol for a Retrospective Cohort Study
  14. 29494
    “…METHODS: All Danish CRC survivors above 18, diagnosed and treated with curative intent between 2014 and 2018, were located through a national patient registry. …”
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    Validity and screening capacity of the FCR-1r for fear of cancer recurrence in long-term colorectal cancer survivors
  15. 29495
    “…BACKGROUND: Chemotherapy-induced peripheral neuropathy (CIPN) is an under-recognized complication of several chemotherapy agents used as part of curative-intent therapy for Hodgkin Lymphoma (HL). …”
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    Performance of the FACT-GOG-Ntx to assess chemotherapy-induced peripheral neuropathy (CIPN) in pediatric high risk Hodgkin lymphoma: report from the Children’s Oncology Group AHOD 1331 study
  16. 29496
    “…Through a deep text mining, the structures of phytocompounds (= ligands) of MC were curated from ChemSpider, PubChem, and ZINC databases and docked into protein targets, AChE (PDB 1EVE) and BChE (PDB 1P0I) after initial in silico preparedness and binding affinity (BA; kcal/mol) reported as an endpoint. …”
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    Chemo- and bio-informatics insight into anti-cholinesterase potentials of berries and leaves of Myrtus communis L., Myrtaceae: an in vitro/in silico study
  17. 29497
    “…Therefore, in order to lower the morbidity and mortality from chronic kidney disease among type 2 diabetic patients, it is advised to develop both preventive and curative intervention strategies, such as raising awareness, creating a supportive environment, and prescribing appropriate medication at an early stage.…”
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    Prevalence and predictors of chronic kidney disease among type 2 diabetic patients worldwide, systematic review and meta-analysis
  18. 29498
    por Papadopoulos, Nikolaos G, Agache, Ioana, Bavbek, Sevim, Bilo, Beatrice M, Braido, Fulvio, Cardona, Victoria, Custovic, Adnan, deMonchy, Jan, Demoly, Pascal, Eigenmann, Philippe, Gayraud, Jacques, Grattan, Clive, Heffler, Enrico, Hellings, Peter W, Jutel, Marek, Knol, Edward, Lötvall, Jan, Muraro, Antonella, Poulsen, Lars K, Roberts, Graham, Schmid-Grendelmeier, Peter, Skevaki, Chrysanthi, Triggiani, Massimo, vanRee, Ronald, Werfel, Thomas, Flood, Breda, Palkonen, Susanna, Savli, Roberta, Allegri, Pia, Annesi-Maesano, Isabella, Annunziato, Francesco, Antolin-Amerigo, Dario, Apfelbacher, Christian, Blanca, Miguel, Bogacka, Ewa, Bonadonna, Patrizia, Bonini, Matteo, Boyman, Onur, Brockow, Knut, Burney, Peter, Buters, Jeroen, Butiene, Indre, Calderon, Moises, Cardell, Lars Olaf, Caubet, Jean-Christoph, Celenk, Sevcan, Cichocka-Jarosz, Ewa, Cingi, Cemal, Couto, Mariana, deJong, Nicolette, Del Giacco, Stefano, Douladiris, Nikolaos, Fassio, Filippo, Fauquert, Jean-Luc, Fernandez, Javier, Rivas, Montserrat Fernandez, Ferrer, Marta, Flohr, Carsten, Gardner, James, Genuneit, Jon, Gevaert, Philippe, Groblewska, Anna, Hamelmann, Eckard, Hoffmann, Hans Jürgen, Hoffmann-Sommergruber, Karin, Hovhannisyan, Lilit, Hox, Valérie, Jahnsen, Frode L, Kalayci, Ömer, Kalpaklioglu, Ayse Füsun, Kleine-Tebbe, Jörg, Konstantinou, George, Kurowski, Marcin, Lau, Susanne, Lauener, Roger, Lauerma, Antti, Logan, Kirsty, Magnan, Antoine, Makowska, Joanna, Makrinioti, Heidi, Mangina, Paraskevi, Manole, Felicia, Mari, Adriano, Mazon, Angel, Mills, Clare, Mingomataj, ErvinÇ, Niggemann, Bodo, Nilsson, Gunnar, Ollert, Markus, O'Mahony, Liam, O'Neil, Serena, Pala, Gianni, Papi, Alberto, Passalacqua, Gianni, Perkin, Michael, Pfaar, Oliver, Pitsios, Constantinos, Quirce, Santiago, Raap, Ulrike, Raulf-Heimsoth, Monika, Rhyner, Claudio, Robson-Ansley, Paula, Alves, Rodrigo Rodrigues, Roje, Zeljka, Rondon, Carmen, Rudzeviciene, Odilija, Ruëff, Franziska, Rukhadze, Maia, Rumi, Gabriele, Sackesen, Cansin, Santos, Alexandra F, Santucci, Annalisa, Scharf, Christian, Schmidt-Weber, Carsten, Schnyder, Benno, Schwarze, Jürgen, Senna, Gianenrico, Sergejeva, Svetlana, Seys, Sven, Siracusa, Andrea, Skypala, Isabel, Sokolowska, Milena, Spertini, Francois, Spiewak, Radoslaw, Sprikkelman, Aline, Sturm, Gunter, Swoboda, Ines, Terreehorst, Ingrid, Toskala, Elina, Traidl-Hoffmann, Claudia, Venter, Carina, Vlieg-Boerstra, Berber, Whitacker, Paul, Worm, Margitta, Xepapadaki, Paraskevi, Akdis, Cezmi A
    Publicado 2012
    “…As in many other chronic diseases, effective prevention, curative treatment and accurate, rapid diagnosis represent major unmet needs. …”
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    Research needs in allergy: an EAACI position paper, in collaboration with EFA
  19. 29499
    por Dawson, Harry D, Loveland, Jane E, Pascal, Géraldine, Gilbert, James GR, Uenishi, Hirohide, Mann, Katherine M, Sang, Yongming, Zhang, Jie, Carvalho-Silva, Denise, Hunt, Toby, Hardy, Matthew, Hu, Zhiliang, Zhao, Shu-Hong, Anselmo, Anna, Shinkai, Hiroki, Chen, Celine, Badaoui, Bouabid, Berman, Daniel, Amid, Clara, Kay, Mike, Lloyd, David, Snow, Catherine, Morozumi, Takeya, Cheng, Ryan Pei-Yen, Bystrom, Megan, Kapetanovic, Ronan, Schwartz, John C, Kataria, Ranjit, Astley, Matthew, Fritz, Eric, Steward, Charles, Thomas, Mark, Wilming, Laurens, Toki, Daisuke, Archibald, Alan L, Bed’Hom, Bertrand, Beraldi, Dario, Huang, Ting-Hua, Ait-Ali, Tahar, Blecha, Frank, Botti, Sara, Freeman, Tom C, Giuffra, Elisabetta, Hume, David A, Lunney, Joan K, Murtaugh, Michael P, Reecy, James M, Harrow, Jennifer L, Rogel-Gaillard, Claire, Tuggle, Christopher K
    Publicado 2013
    “…RESULTS: The Immune Response Annotation Group (IRAG) used computational curation and manual annotation of the swine genome assembly 10.2 (Sscrofa10.2) to refine the currently available automated annotation of 1,369 immunity-related genes through sequence-based comparison to genes in other species. …”
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    Structural and functional annotation of the porcine immunome
  20. 29500
    “…All predictions were evaluated on a set of 7,522 chemicals curated from the literature. To overcome the limitations of single models, a consensus was built by weighting models on scores based on their evaluated accuracies. …”
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    CERAPP: Collaborative Estrogen Receptor Activity Prediction Project
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