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29521por Sinclair, Marlene, McCullough, Julie E M, Elliott, David, Braz, Paula, Cavero-Carbonell, Clara, Dornan, Lesley, Jamry-Dziurla, Anna, João Santos, Ana, Latos-Bieleńska, Anna, Machado, Ausenda, Páramo-Rodríguez, Lucía“…Achievement of these results required dedicated time management, social media expertise, creativity, and sharing knowledge to curate valuable content. CONCLUSIONS: Building and maintaining a multilayered online forum for coproduction and information sharing is challenging. …”
Publicado 2021
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29522“…In order to find a novel treating project for rUTI to increase the clinical curative effect, we thus try to combine TLF with CLAT to treat rUTI and design an optimized, pragmatically clinical trial to evaluate the efficacy and safety of this project. …”
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29523por Liu, Hao, Li, Danxiu, Sun, Lina, Qin, Hongqiang, Fan, Ahui, Meng, Lingnan, Graves-Deal, Ramona, Glass, Sarah E., Franklin, Jeffrey L., Liu, Qi, Wang, Jing, Yeatman, Timothy J., Guo, Hao, Zong, Hong, Jin, Shuilin, Chen, Zhiyu, Deng, Ting, Fang, Ying, Li, Cunxi, Karijolich, John, Patton, James G., Wang, Xin, Nie, Yongzhan, Fan, Daiming, Coffey, Robert J., Zhao, Xiaodi, Lu, Yuanyuan“…METHODS: The correlation between MIR100HG and EMT was analyzed by curating public CRC data repositories. The biological roles of MIR100HG in EMT, metastasis and cetuximab resistance in CRC were determined both in vitro and in vivo. …”
Publicado 2022
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29524por Perfors, I. A. A., Helsper, C. W., Noteboom, E. A., Visserman, E. A., van Dorst, E. B. L., van Dalen, T., Verhagen, M. A. M. T., Witkamp, A. J., Koelemij, R., Flinterman, A. E., Pruissen-Peeters, K. A. B. M., Schramel, F. M. N. H., van Rens, M. T. M., Ernst, M. F., Moons, L. M. G., van der Wall, E., de Wit, N. J., May, A. M.“…METHODS: We performed a multicentre randomised controlled trial enrolling patients curatively treated for breast, lung, colorectal, gynaecologic cancer or melanoma. …”
Publicado 2022
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29525por Zhang, Rui, Zhang, Qingqing, Chen, Yanni, Zhao, Qing, Zhang, Bo, Wang, Ling, Zhou, Chungen, Zhang, Qi, Chen, Kun, Zhang, Yuqing, Hou, Xiaotao, Chen, Hao, Liu, Xingyin, Ni, Min, Jiang, Bin“…Currently, there are no curative interventions for IBD, and all available treatments have side effects that limit their use. …”
Publicado 2022
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29526por Borde, Julika, Laitman, Yael, Blümcke, Britta, Niederacher, Dieter, Weber-Lassalle, Konstantin, Sutter, Christian, Rump, Andreas, Arnold, Norbert, Wang-Gohrke, Shan, Horváth, Judit, Gehrig, Andrea, Schmidt, Gunnar, Dutrannoy, Véronique, Ramser, Juliane, Hentschel, Julia, Meindl, Alfons, Schroeder, Christopher, Wappenschmidt, Barbara, Engel, Christoph, Kuchenbaecker, Karoline, Schmutzler, Rita K., Friedman, Eitan, Hahnen, Eric, Ernst, Corinna“…METHODS: Overall, estrogen receptor (ER)-positive, and ER-negative BC PRSs as developed by Kuchenbaecker et al. for BC risk discrimination in female BRCA1/2 PV carriers were employed for PRS computation in a curated sample of 295 women of European descent carrying PVs in the BRCA1 (n=183) or the BRCA2 gene (n=112), and did either fulfill the ED criteria (n=162, mean age at diagnosis: 28.3 years, range: 20 to 34 years) or the LD criteria (n=133). …”
Publicado 2022
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29527“…To improve the framework’s generalizability, an independent training dataset with 9,424 samples was curated from different databases including GTOS and MINC-2500, and used for pretrained models’ (e.g., MobileNetV2) fine-tuning. …”
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29528por Liang, Zhigang, Zhang, Junliang, Huang, Shuangfeng, Yang, Shaowan, Xu, Luyao, Xiang, Wei, Zhang, Manman“…The secondary outcome measure is curative efficacy which were evaluated by the 7d-NIHSS score and functional outcomes at 90 days. …”
Publicado 2022
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29529“…Members appreciated the access to resources; quarterly meetings (n = 11/11), and a curated reading list (n = 8/11) were the most valued resources. …”
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29530por Li, Zhenhui, Zhu, Haibin, Pang, Xiaolin, Mao, Yun, Yi, Xiaoping, Li, Chunxia, Lei, Ming, Cheng, Xianshuo, Liang, Lei, Wu, Jiamei, Ding, Yingying, Yang, Jun, Sun, Yingshi, Zhang, Tao, You, Dingyun, Liu, Zaiyi“…METHODS: Consecutive patients with CRC who underwent curative resection for stage II-III colorectal adenocarcinoma at five hospitals were collected. …”
Publicado 2022
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29531por He, Cailin, Wang, Yang, Wen, Yuqi, Li, Teng, Hu, En, Zeng, Siqing, Yang, Bo, Xiong, Xingui“…Arraystar rat lncRNA-mRNA chip technology was used to determine the lncRNA and mRNA expression profiles of the Control, CIA and BZXD groups, and to screen gene expression profiles related to the curative effect of BZXD. A lncRNA-mRNA co-expression network was constructed for the therapeutic efficacy genes. …”
Publicado 2022
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29532“…These databases are populated via manual curation, which is challenging to scale with an exponentially rising publication rate. …”
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29533por Mohammed Taha, Hiba, Aalizadeh, Reza, Alygizakis, Nikiforos, Antignac, Jean-Philippe, Arp, Hans Peter H., Bade, Richard, Baker, Nancy, Belova, Lidia, Bijlsma, Lubertus, Bolton, Evan E., Brack, Werner, Celma, Alberto, Chen, Wen-Ling, Cheng, Tiejun, Chirsir, Parviel, Čirka, Ľuboš, D’Agostino, Lisa A., Djoumbou Feunang, Yannick, Dulio, Valeria, Fischer, Stellan, Gago-Ferrero, Pablo, Galani, Aikaterini, Geueke, Birgit, Głowacka, Natalia, Glüge, Juliane, Groh, Ksenia, Grosse, Sylvia, Haglund, Peter, Hakkinen, Pertti J., Hale, Sarah E., Hernandez, Felix, Janssen, Elisabeth M.-L., Jonkers, Tim, Kiefer, Karin, Kirchner, Michal, Koschorreck, Jan, Krauss, Martin, Krier, Jessy, Lamoree, Marja H., Letzel, Marion, Letzel, Thomas, Li, Qingliang, Little, James, Liu, Yanna, Lunderberg, David M., Martin, Jonathan W., McEachran, Andrew D., McLean, John A., Meier, Christiane, Meijer, Jeroen, Menger, Frank, Merino, Carla, Muncke, Jane, Muschket, Matthias, Neumann, Michael, Neveu, Vanessa, Ng, Kelsey, Oberacher, Herbert, O’Brien, Jake, Oswald, Peter, Oswaldova, Martina, Picache, Jaqueline A., Postigo, Cristina, Ramirez, Noelia, Reemtsma, Thorsten, Renaud, Justin, Rostkowski, Pawel, Rüdel, Heinz, Salek, Reza M., Samanipour, Saer, Scheringer, Martin, Schliebner, Ivo, Schulz, Wolfgang, Schulze, Tobias, Sengl, Manfred, Shoemaker, Benjamin A., Sims, Kerry, Singer, Heinz, Singh, Randolph R., Sumarah, Mark, Thiessen, Paul A., Thomas, Kevin V., Torres, Sonia, Trier, Xenia, van Wezel, Annemarie P., Vermeulen, Roel C. H., Vlaanderen, Jelle J., von der Ohe, Peter C., Wang, Zhanyun, Williams, Antony J., Willighagen, Egon L., Wishart, David S., Zhang, Jian, Thomaidis, Nikolaos S., Hollender, Juliane, Slobodnik, Jaroslav, Schymanski, Emma L.“…Each list is available for separate download. The merged, curated collection is also available as the NORMAN Substance Database (NORMAN SusDat). …”
Publicado 2022
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29534por Balogun, Toheeb A., Chukwudozie, Onyeka S., Ogbodo, Uchechukwu C., Junaid, Idris O., Sunday, Olugbodi A., Ige, Oluwasegun M., Aborode, Abdullahi T., Akintayo, Abiola D., Oluwarotimi, Emmanuel A., Oluwafemi, Isaac O., Saibu, Oluwatosin A., Chuckwuemaka, Prosper, Omoboyowa, Damilola A., Alausa, Abdullahi O., Atasie, Nkechi H., Ilesanmi, Ayooluwa, Dairo, Gbenga, Tiamiyu, Zainab A., Batiha, Gaber E., Alkhuriji, Afrah Fahad, Al-Megrin, Wafa Abdullah I., De Waard, Michel, Sabatier, Jean-Marc“…Therefore, using high-throughput virtual screening, manually curated compounds library from some medicinal plants were screened against four main drivers of SARS-CoV-2 (spike glycoprotein, PLpro, 3CLpro, and RdRp). …”
Publicado 2022
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29535por Liu, Yanxia, Gao, Yuan, Wang, Ying, Zhao, Cong, Zhang, Zhiyun, Li, Baolan, Zhang, Tongmei“…Clinical characteristics, treatment scheme, clinical curative effect and follow-up data of enrolled patients were collected for analysis. …”
Publicado 2022
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29536por Du, Kun, Bai, Xue, Chen, Li, Shi, Yu, Wang, Hao-ding, Cai, Ming-cheng, Sun, Wen-qiang, Wang, Jie, Chen, Shi-yi, Jia, Xian-bo, Lai, Song-jia“…BAT losses thermogenic capacity and gains a “white adipose tissue-like” phenotype (“BAT whitening”) under thermoneutral environments, which is a potential factor causing a low curative effect in BAT-related obesity treatments. …”
Publicado 2022
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29537por Nanfack, Aubin Joseph, Ambada Ndzengue, Georgia Elna, Fokam, Joseph, Ka'e, Aude Christelle, Sonela, Nelson, Kenou, Leslie, Tsoptio, Michelle, Sagnia, Bertrand, Elong, Elise, Beloumou, Grace, Perno, Carlo Federico, Colizzi, Vittorio, Ndjolo, Alexis“…Unfortunately, ART is not curative and must be taken for life, because within a few weeks of treatment cessation, HIV viremia rebounds in most patients except for rare elite or posttreatment controllers of viremia. …”
Publicado 2022
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29538por Yin, Liangyu, Cui, Jiuwei, Lin, Xin, Li, Long, Li, Na, Fan, Yang, Zhang, Ling, Liu, Jie, Chong, Feifei, Lu, Zongliang, Wang, Chang, Liang, Tingting, Liu, Xiangliang, Deng, Li, Yang, Mei, Yu, Jiami, Wang, Xiaojie, Cong, Minghua, Li, Zengning, Weng, Min, Yao, Qinghua, Jia, Pingping, Guo, Zengqing, Li, Wei, Song, Chunhua, Shi, Hanping, Xu, Hongxia“…This association was significantly strengthened in patients who did not receive curative chemotherapy (HR = 1.491, 95% CI = 1.298–1.713), those who had higher serum total protein levels (HR = 1.469, 95% CI = 1.284–1.681) and those with better physical performance (HR = 1.453, 95% CI = 1.271–1.662). …”
Publicado 2022
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29539por Ferrari, Cristina, Santo, Giulia, Mammucci, Paolo, Rubini, Dino, Sciacqua, Alessio, Sardaro, Angela, Pisani, Antonio Rosario, Rubini, Giuseppe“…In most cases, patients present a locally advanced disease at diagnosis and non-surgical curative treatment is considered the standard of care. …”
Publicado 2023
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29540“…RESULTS: LSG members and health staff felt that the PHC was an institution that guarantees preventive, promotive, and curative care to the poorest section of society and can help in reducing the high cost of care. …”
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