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  1. 29541
    “…OBJECTIVE: Our goal was to devise a new methodology to extract, transform, and load existing health data sets into HL7 FHIR repositories in line with FAIR principles, develop a Data Curation Tool to implement the methodology, and evaluate it on health data sets from 2 different but complementary institutions. …”
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    Online Artículo Texto
    A Data Transformation Methodology to Create Findable, Accessible, Interoperable, and Reusable Health Data: Software Design, Development, and Evaluation Study
  2. 29542
    por Akerman, Anouschka, Milogiannakis, Vanessa, Jean, Tyra, Esneau, Camille, Silva, Mariana Ruiz, Ison, Timothy, Fichter, Christina, Lopez, Joseph A., Chandra, Deborah, Naing, Zin, Caguicla, Joanna, Li, Daiyang, Walker, Gregory, Amatayakul-Chantler, Supavadee, Roth, Nathan, Manni, Sandro, Hauser, Thomas, Barnes, Thomas, Condylios, Anna, Yeang, Malinna, Wong, Maureen, Foster, Charles S.P., Sato, Kenta, Lee, Sharon, Song, Yang, Mao, Lijun, Sigmund, Allison, Phu, Amy, Vande More, Ann Marie, Hunt, Stephanie, Douglas, Mark, Caterson, Ian, Britton, Warwick, Sandgren, Kerrie, Bull, Rowena, Lloyd, Andrew, Triccas, Jamie, Tangye, Stuart, Bartlett, Nathan W., Darley, David, Matthews, Gail, Stark, Damien J., Petoumenos, Kathy, Rawlinson, William D., Murrell, Ben, Brilot, Fabienne, Cunningham, Anthony L., Kelleher, Anthony D., Aggarwal, Anupriya, Turville, Stuart G.
    Publicado 2023
    “…METHODS: Over the course of 2022, we monitored the potency and breadth of antibody neutralization responses to many emerging variants in the Australian community at three levels: (i) we tracked over 420,000 U.S. plasma donors over time through various vaccine booster roll outs and Omicron waves using sequentially collected IgG pools; (ii) we mapped the antibody response in individuals using blood from stringently curated vaccine and convalescent cohorts. (iii) finally we determine the in vitro efficacy of clinically approved therapies Evusheld and Sotrovimab. …”
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    Online Artículo Texto
    Emergence and antibody evasion of BQ, BA.2.75 and SARS-CoV-2 recombinant sub-lineages in the face of maturing antibody breadth at the population level
  3. 29543
    “…However, few studies explored the safety and long-term outcome of EIPL after curative gastrectomy. AIM: To evaluate the efficacy and long-term outcome of advanced GC patients treated with EIPL. …”
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    Efficacy and outcome of extensive intraoperative peritoneal lavage plus surgery vs surgery alone with advanced gastric cancer patients
  4. 29544
    “…ABSTRACT: Due to poor compliance and uptake of LDCT screening among high-risk populations, lung cancer is often diagnosed in advanced stages where treatment is rarely curative. Based upon the American College of Radiology’s Lung Imaging and Reporting Data System (Lung-RADS) 80–90% of patients screened will have clinically “non-actionable” nodules (Lung-RADS 1 or 2), and those harboring larger, clinically “actionable” nodules (Lung-RADS 3 or 4) have a significantly greater risk of lung cancer. …”
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    Online Artículo Texto
    Development of a Novel Circulating Autoantibody Biomarker Panel for the Identification of Patients with ‘Actionable’ Pulmonary Nodules
  5. 29545
    “…BACKGROUND: Chimeric antigen receptor T-cell (CAR-T) cell therapies have been claimed to be curative in responsive patients. Nonetheless, response rates can vary according to different characteristics, and these therapies are associated with important adverse events such as cytokine release syndrome, neurologic adverse events, and B-cell aplasia. …”
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    Efficacy and safety of chimeric antigen receptor T-cell (CAR-T) therapy in hematologic malignancies: a living systematic review on comparative studies
  6. 29546
    “…PURPOSE/OBJECTIVE: Radiotherapy to the prostate bed is a potentially curative salvage option after radical prostatectomy. …”
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    Online Artículo Texto
    ESTRO ACROP guideline on prostate bed delineation for postoperative radiotherapy in prostate cancer
  7. 29547
    “…Owing to the different equipment and intervention programs of telerehabilitation, its curative effect on the static balance and reactive balance of stroke patients may be different. …”
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    Online Artículo Texto
    The effect of telerehabilitation on balance in stroke patients: is it more effective than the traditional rehabilitation model? A meta-analysis of randomized controlled trials published during the COVID-19 pandemic
  8. 29548
    “…Dual-energy CT image acquisitions with two separate kVs were curated to generate paired training data between a single-kV CT image and the corresponding two material basis images. …”
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    Online Artículo Texto
    A quality-checked and physics-constrained deep learning method to estimate material basis images from single-kV contrast-enhanced chest CT scans
  9. 29549
    “…IMPORTANCE: Sentinel lymph node biopsy (SLNB) is the standard of care for axillary node staging of patients with early breast cancer (BC), but its necessity can be questioned since surgery for examination of axillary nodes is not performed with curative intent. OBJECTIVE: To determine whether the omission of axillary surgery is noninferior to SLNB in patients with small BC and a negative result on preoperative axillary lymph node ultrasonography. …”
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    Online Artículo Texto
    Sentinel Lymph Node Biopsy vs No Axillary Surgery in Patients With Small Breast Cancer and Negative Results on Ultrasonography of Axillary Lymph Nodes: The SOUND Randomized Clinical Trial
  10. 29550
    “…The source of ectopic ACTH secretion should be established after diagnosis because the excision of an ACTH-producing tumor can be curative. Presentation: Thursday, June 15, 2023…”
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    THU012 Incidental Pituitary Adenoma In A Patient With Ectopic ACTH Secreting Cushing Syndrome - A Diagnostic Conundrum
  11. 29551
    “…To better demonstrate this phase, we prepared a benchmark dataset of carefully curated clinical and biochemical markers based on clinician assessments for survival and kidney injury prediction in COVID-19 patients. …”
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    COVID-Net Biochem: an explainability-driven framework to building machine learning models for predicting survival and kidney injury of COVID-19 patients from clinical and biochemistry data
  12. 29552
    “…ABSTRACT: Oligometastatic disease (OMD) is currently known as an intermediate state of cancer, characterized by a limited number of systemic metastatic lesions for which local ablative therapy could be curative. Indeed, data from multiple clinical trials have illustrated an increase in overall survival (OS) for cancer patients when local ablative therapy was included in the systemic adjuvant therapy. …”
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    Online Artículo Texto
    Oligometastatic Disease (OMD): The Classification and Practical Review of Prospective Trials
  13. 29553
    “…Virtual reality (VR) allows for the creation of a therapist-curated, computer-generated social space that potentially enables support groups for this population. …”
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    Use of Immersive Virtual Reality Spaces to Engage Adolescent and Young Adult Patients With Cancer in Therapist-Guided Support Groups: Protocol for a Pre-Post Study
  14. 29554
    “…The raw data set derived from the aggregator tool was automatically screened for the relevancy of posts, generating the curated data set that was manually reviewed to identify posts that fell within the predefined inclusion and exclusion criteria. …”
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    Understanding the Needs and Lived Experiences of Patients With Graft-Versus-Host Disease: Real-World European Public Social Media Listening Study
  15. 29555
    “…Eligible patients had a newly diagnosed clinical stage T3–4 N0–2 M0 rectal adenocarcinoma located within 12 cm of the anal verge suitable for curative resection. Surgery was performed 4–6 weeks from completion of preoperative chemoradiotherapy. …”
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    A phase I trial of preoperative radiotherapy and capecitabine for locally advanced, potentially resectable rectal cancer
  16. 29556
    “…METHODS: A 132 of 143 patients who underwent curative resection for colorectal cancer were enrolled in this study. 11 patients with resection margin positive were excluded. …”
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    Clinical significance of preoperative serum vascular endothelial growth factor, interleukin-6, and C-reactive protein level in colorectal cancer
  17. 29557
    “…FINDINGS: One hundred and fifty-six consecutive patients (median age 58 years) with cervix cancer FIGO stages IB–IVA were treated with definitive radiotherapy in curative intent. Histology was squamous cell cancer in 134 patients (86%), tumour size was >5 cm in 103 patients (66%), lymph node involvement in 75 patients (48%). …”
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    Clinical outcome of protocol based image (MRI) guided adaptive brachytherapy combined with 3D conformal radiotherapy with or without chemotherapy in patients with locally advanced cervical cancer
  18. 29558
    “…RESULTS: We provide a review of published approaches for predicting RNA-binding residues in proteins and a systematic comparison and critical assessment of protein-RNA interface residue predictors trained using these approaches on three carefully curated non-redundant datasets. We directly compare two widely used machine learning algorithms (Naïve Bayes (NB) and Support Vector Machine (SVM)) using three different data representations in which features are encoded using either sequence- or structure-based windows. …”
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    Online Artículo Texto
    Protein-RNA interface residue prediction using machine learning: an assessment of the state of the art
  19. 29559
    “…A set of 84 terms, selected from 143 curated terms was organized within each node reflecting topics within the disaster and global health in crisis literature. …”
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    A Framework and Methodology for Navigating Disaster and Global Health in Crisis Literature
  20. 29560
    “…BACKGROUND: Pressure ulcer (PU) is common in immobile elderly patients, and there are some research works to investigate a preventive and curative method, but not to find sufficient effectiveness. …”
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    Hydrogen water intake via tube-feeding for patients with pressure ulcer and its reconstructive effects on normal human skin cells in vitro
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