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29641por Johnson, Kai Conrad Cecil, Goldstein, Daniel, Tharakan, Jasmin, Quiroga, Dionisia, Kassem, Mahmoud, Grimm, Michael, Miah, Abdul, Vargo, Craig, Berger, Michael, Sudheendra, Preeti, Pariser, Ashley, Gatti-Mays, Margaret E., Williams, Nicole, Stover, Daniel, Sardesai, Sagar, Wesolowski, Robert, Ramaswamy, Bhuvaneswari, Tozbikian, Gary, Schnell, Patrick M., Cherian, Mathew A.“…CONCLUSION: Our findings demonstrate that dexamethasone has no clinically significant impact on pCR, RFS, or OS when given concurrently with NAC in patients with curative TNBC, regardless of diabetic status.…”
Publicado 2023
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29642por Oprea-Lager, Daniela-Elena, Gontier, Eric, García-Cañamaque, Lina, Gauthé, Mathieu, Olivier, Pierre, Mitjavila, Mercedes, Tamayo, Pilar, Robin, Philippe, García Vicente, Ana Maria, Bouyeure, Anne-Charlotte, Bailliez, Alban, Rodríguez-Fernández, Antonio, Mahmoud, Sinan Ben, Vallejo-Casas, Juan Antonio, Maksud, Philippe, Merlin, Charles, Blanc-Durand, Paul, Drouet, Clément, Tissot, Hubert, Vierasu, Irina, Vander Borght, Thierry, Boos, Evelyne, Chossat, Florence, Hodolic, Marina, Rousseau, Caroline“…Men with rising prostate-specific antigen (PSA) after initial curative therapy were enrolled. [(18)F]DCFPyL and [(18)F]fluoromethylcholine PET/CTs were performed within a maximum time interval of 12 days. …”
Publicado 2023
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29643por Peng, Weicheng, Zhao, Rui, Guan, Feng, Liang, Xin, Jing, Bei, Zhu, Guangtong, Mao, Beibei, Hu, Zhiqiang“…Fully E-MVD for the treatment of NVC has advantages and techniques not available with microscopic MVD, which may reduce the incidence of surgical complications while improving the curative effect and reducing the recurrence rate. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12893-023-02214-0.…”
Publicado 2023
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29644por Virdee, Pradeep S, Moschandreas, Joanna, Gebski, Val, Love, Sharon B, Francis, E Anne, Wasan, Harpreet S, van Hazel, Guy, Gibbs, Peter, Sharma, Ricky A“…METHODS: Eligible patients are adults with histologically confirmed CRC and unequivocal evidence of liver metastases which are not treatable by surgical resection or local ablation with curative intent at the time of study entry. Patients may also have limited extrahepatic metastases. …”
Publicado 2017
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29645por Jia, Yifan, Shu, Xin, Yang, Xiaoan, Sun, Haixia, Cao, Huijuan, Cao, Hong, Zhang, Ka, Xu, Qihuan, Li, Gang, Yang, Yang“…Prolonging the treatment course can increase the curative effect of UCMSCs for end-stage liver disease, especially for patients with cirrhosis.…”
Publicado 2020
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29646por Sriphoosanaphan, Supachaya, Thanapirom, Kessarin, Suksawatamnuay, Sirinporn, Thaimai, Panarat, Sittisomwong, Sukanya, Sonsiri, Kanokwan, Srisoonthorn, Nunthiya, Teeratorn, Nicha, Tanpowpong, Nattaporn, Chaopathomkul, Bundit, Treeprasertsuk, Sombat, Poovorawan, Yong, Komolmit, Piyawat“…The 25(OH)VD levels decreased from 26.3 ± 10.7 ng/mL at baseline to 20.8 ± 8.1 and 20.8 ± 8.5 ng/mL at 24 and 48 weeks, respectively (p < 0.001). CONCLUSIONS: Curative treatment with DAA attenuated the liver stiffness and inflammation but did not improve VD levels. …”
Publicado 2020
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29647por Bi, Junjie, Yang, Wei, Hao, Ping, Zhao, Yongmei, Wei, Dan, Sun, Yipeng, Lin, Yuhua, Sun, Meng, Chen, Xuan, Luo, Xuming, Li, Shanqun, Zhang, Wei, Wang, Xiongbiao“…The patients were very satisfied with the WeChat management because of the obvious curative effect and home feeling. CONCLUSIONS: The WeChat platform provided a feasible, effective, and sustainable management plan for Baduanjin rehabilitation. …”
Publicado 2021
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29648por Kipourou, Dimitra-Kleio, Leyrat, Clémence, Alsheridah, Nourah, Almazeedi, Sulaiman, Al-Youha, Sarah, Jamal, Mohammad H., Al-Haddad, Mohannad, Al-Sabah, Salman, Rachet, Bernard, Belot, Aurélien“…BACKGROUND: Subsequent epidemic waves have already emerged in many countries and in the absence of highly effective preventive and curative options, the role of patient characteristics on the development of outcomes needs to be thoroughly examined, especially in middle-east countries where such epidemiological studies are lacking. …”
Publicado 2021
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29649por Guberina, Maja, Darwiche, Kaid, Hautzel, Hubertus, Pöttgen, Christoph, Guberina, Nika, Gauler, Thomas, Ploenes, Till, Umutlu, Lale, Theegarten, Dirk, Aigner, Clemens, Eberhardt, Wilfried E. E., Metzenmacher, Martin, Wiesweg, Marcel, Karpf-Wissel, Rüdiger, Schuler, Martin, Herrmann, Ken, Stuschke, Martin“…Inclusion criteria were curative treatment intent, (18)F-FDG PET/CT and EBUS-TBNA prior to start of treatment. …”
Publicado 2021
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29650“…BACKGROUND: Haematopoietic stem cell transplantation (HSCT) is used worldwide in various malignant and nonmalignant childhood diseases, including haematologic, genetic, autoimmune and metabolic disorders, and is the only curative treatment for many of these illnesses. The survival rates of many childhood diseases have been increased due to HSCT treatment. …”
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29651por Kong, Jun, Gao, Meng-Ge, Qin, Ya-Zhen, Wang, Yu, Yan, Chen-Hua, Sun, Yu-Qian, Chang, Ying-Jun, Xu, Lan-Ping, Zhang, Xiao-Hui, Liu, Kai-Yan, Huang, Xiao-Jun, Zhao, Xiao-Su“…Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is currently one of the curative therapies available for AML and MDS with excess blasts (MDS-EB). …”
Publicado 2022
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29652por Ying, Hou-Qun, Chen, Wei, Xiong, Cui-Fen, Wang, Yuanyuan, Li, Xiao-Juan, Cheng, Xue-Xin“…No significant difference in recurrence rate was observed between L-FPR (≤ 15) patients with (10.00%) or without CT (9.76%), indicating that these patients might not require to receive adjuvant CT after curative resection. CONCLUSIONS: Preoperative FPR combined with CEA is superior to common tumor biomarkers, FPR, or AFR in distinguishing early-stage CRC from benign colorectal polyps. …”
Publicado 2022
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29653por Guberina, Nika, Pöttgen, Christoph, Schuler, Martin, Guberina, Maja, Stamatis, Georgios, Plönes, Till, Metzenmacher, Martin, Theegarten, Dirk, Gauler, Thomas, Darwiche, Kaid, Aigner, Clemens, Eberhardt, Wilfried E. E., Stuschke, Martin“…METHODS: All consecutive patients with histopathologically confirmed NSCLC (cT4 cN0/1 cM0) with a curative-intent-to-treat (cc)RTx/CTx were included between 01.01.2001 and 01.07.2019. …”
Publicado 2022
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29654por Chauhan, Shekhar, Kumar, Shubham, Patel, Ratna, Simon, David Jean, Kumari, Aradhana“…In a developing country like India, preventive measures, rather than curative measures of communicable diseases, will be cost-effective and helpful. …”
Publicado 2022
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29655por Fan, Xiaowen, McKnight, Tory, Neshiwat, Johnathan, Park, Song, Chung, Danna, Li, Xiu-Min“…Despite strict avoidance of food allergens, a subgroup of sensitive individuals still develops frequent, persistent, and difficult to treat hives (FPDTH) for which there is no curative therapy. Although these cases are rare, these patients are in most need of therapy. …”
Publicado 2022
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29656por Casarotto, Mariateresa, Lupato, Valentina, Giurato, Giorgio, Guerrieri, Roberto, Sulfaro, Sandro, Salvati, Annamaria, D’Angelo, Elisa, Furlan, Carlo, Menegaldo, Anna, Baboci, Lorena, Montico, Barbara, Turturici, Irene, Dolcetti, Riccardo, Romeo, Salvatore, Baggio, Vittorio, Corrado, Stefania, Businello, Gianluca, Guido, Maria, Weisz, Alessandro, Giacomarra, Vittorio, Franchin, Giovanni, Steffan, Agostino, Sigalotti, Luca, Vaccher, Emanuela, Boscolo-Rizzo, Paolo, Jerry, Polesel, Fanetti, Giuseppe, Fratta, Elisabetta“…RESULTS: In this study, DNA was extracted from 163 formalin-fixed paraffin-embedded tissue samples retrospectively collected from stage III-IVB OPSCC patients managed with curative intent with up-front treatment. Quantitative methylation-specific PCR revealed that LINE-1 hypomethylation was directly associated with poor prognosis (5-year overall survival—OS: 28.1% for LINE-1 methylation < 35% vs. 69.1% for ≥ 55%; p < 0.0001). …”
Publicado 2022
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29657por Li, Shuang, Liu, Hui, Ruan, Zhe, Guo, Rongjing, Sun, Chao, Tang, Yonglan, Huang, Xiaoxi, Gao, Ting, Hao, Sijia, Li, Huanhuan, Song, Na, Su, Yue, Ning, Fan, Li, Zhuyi, Chang, Ting“…METHODS: The GSE85452 dataset with MG and healthy samples was downloaded from Gene Expression Omnibus (GEO) database. m6A modification regulators were manually curated. The targets of m6A regulators were obtained from m6A2Target database. …”
Publicado 2023
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29658“…The treatment options include resection, with or without (neo-/) adjuvant therapy, and conservative therapy, the latter even with curative intent. Contrast-enhanced MRI is used for staging and therapy monitoring. …”
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29659por Herrera, Victoria L. M., Bosch, Nicholas A., Lok, Judith J., Nguyen, Mai Q., Lenae, Kaitriona A., deKay, Joanne T., Ryzhov, Sergey V., Seder, David B., Ruiz-Opazo, Nelson, Walkey, Allan J.“…However, to date, there is no curative intent therapy able to block neutrophil/NETs-mediated progression of multi-organ dysfunction. …”
Publicado 2023
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29660por Lapitz, Ainhoa, Azkargorta, Mikel, Milkiewicz, Piotr, Olaizola, Paula, Zhuravleva, Ekaterina, Grimsrud, Marit M., Schramm, Christoph, Arbelaiz, Ander, O'Rourke, Colm J., La Casta, Adelaida, Milkiewicz, Malgorzata, Pastor, Tania, Vesterhus, Mette, Jimenez-Agüero, Raul, Dill, Michael T., Lamarca, Angela, Valle, Juan W., Macias, Rocio I.R., Izquierdo-Sanchez, Laura, Pérez Castaño, Ylenia, Caballero-Camino, Francisco Javier, Riaño, Ioana, Krawczyk, Marcin, Ibarra, Cesar, Bustamante, Javier, Nova-Camacho, Luiz M., Falcon-Perez, Juan M., Elortza, Felix, Perugorria, Maria J., Andersen, Jesper B., Bujanda, Luis, Karlsen, Tom H., Folseraas, Trine, Rodrigues, Pedro M., Banales, Jesus M.“…PSC), and (iv) prognostic stratification of patients with CCA, which, altogether, may increase the number of cases eligible for potentially curative options or to receive more successful treatments, decreasing CCA-related mortality.…”
Publicado 2023
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