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  1. 29701
    “…DESIGN, SETTING, AND PARTICIPANTS: This prespecified secondary end point analysis of the AVANT and S-AVANT studies included 573 patients with curatively resected high-risk stage II CC and at least 1 of the following criteria: stage T4, bowel obstruction or perforation, blood and/or lymphatic vascular invasion and/or perineural invasion, age younger than 50 years, or fewer than 12 nodes analyzed. …”
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    Association of Bevacizumab Plus Oxaliplatin-Based Chemotherapy With Disease-Free Survival and Overall Survival in Patients With Stage II Colon Cancer: A Secondary Analysis of the AVANT Trial
  2. 29702
    “…We trained the algorithm on a randomly selected part of this dataset (development dataset) and used the rest for testing (internal validation dataset). Additionally, we curated an external validation dataset comprising clinical photographs from six representative journals in the field of dentistry and oral surgery. …”
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    A deep learning algorithm for detection of oral cavity squamous cell carcinoma from photographic images: A retrospective study
  3. 29703
    “…Asymptomatic in its initial stages, PDAC is mostly diagnosed late, when already a locally advanced or metastatic disease, as there are no useful biomarkers for detection in its early stages, when surgery can be curative. We have previously described a promising biomarker panel (LYVE1, REG1A, and TFF1) for earlier detection of PDAC in urine. …”
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    A combination of urinary biomarker panel and PancRISK score for earlier detection of pancreatic cancer: A case–control study
  4. 29704
    “…METHODS: Between 2014 and 2018, patients with histopathologically proven HNSCC, planned for curative (chemo) radiotherapy, were prospectively included. …”
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    Multiparametric functional MRI and (18)F-FDG-PET for survival prediction in patients with head and neck squamous cell carcinoma treated with (chemo)radiation
  5. 29705
    “…It can also help us to better understand the compatibility of TCM prescriptions, thus improving the curative effects. The purpose of this article is to explore the compatibility of TCM prescriptions and identify the most important herbal pair for the treatment of COVID-19, and then analyze the active components and potential mechanisms of this herbal pair. …”
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    The important herbal pair for the treatment of COVID-19 and its possible mechanisms
  6. 29706
    “…BACKGROUND: Surgery is established as only potentially curative treatment for hilar cholangiocarcinoma. However, whether hepatectomy should be preferred to the left-side hepatectomy, which includes left hemihepatectomy, extended left hemihepatectomy, and left trisectionectomy, or right-side hepatectomy, which represents right hemihepatectomy, extended right hemihepatectomy, and right trisectionectomy, is debated. …”
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    Left-side vs. right-side hepatectomy for hilar cholangiocarcinoma: a meta-analysis
  7. 29707
    “…A prospective observational registry in rare disease is feasible and can be a tool to collect curated-population reflective data in orphan diseases. …”
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    The diffuse-type tenosynovial giant cell tumor (dt-TGCT) patient journey: a prospective multicenter study
  8. 29708
    “…Ces biomarqueurs pourraient intégrer la démarche diagnostique d’embolie pulmonaire et à l’initiation rapide d’une anticoagulation curative au cours de la COVID-19, et pourraient inversement réduire le nombre d’angioscanner thoracique non nécessaire.…”
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    Leucocytes, D-dimères et Ferritinémie comme Facteurs Prédictifs Indépendants d’Embolie Pulmonaire suspectée à l’admission chez les patients COVID-19 hospitalisés hors réanimation : étude rétrospective multicentrique française CLOTVID
  9. 29709
    “…SIMPLE SUMMARY: Between 64 and 85% of patients with colorectal liver metastases (CRLM) develop distant intrahepatic recurrence after curative intent local treatment. The current standard of care for new CRLM is repeat local treatment, comprising partial hepatectomy and thermal ablation. …”
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    Thermal Ablation Compared to Partial Hepatectomy for Recurrent Colorectal Liver Metastases: An Amsterdam Colorectal Liver Met Registry (AmCORE) Based Study
  10. 29710
    “…SIMPLE SUMMARY: Over the last two decades, our improved understanding of the pathobiology of androgen-addicted prostate cancer (PCa), and documented therapeutic advances/breakthroughs have not translated into any substantial or sustained curative benefit for patients treated with traditional ADT or novel immune checkpoint blockade therapeutics. …”
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    Differential but Concerted Expression of HSD17B2, HSD17B3, SHBG and SRD5A1 Testosterone Tetrad Modulate Therapy Response and Susceptibility to Disease Relapse in Patients with Prostate Cancer
  11. 29711
    “…Data analysis was conducted from July 15, 2020, to October 21, 2020. EXPOSURES: Curative resection for gastric neuroendocrine carcinoma, gastric mixed adenoneuroendocrine carcinoma, and gastric adenocarcinoma. …”
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    Comparison of Survival and Patterns of Recurrence in Gastric Neuroendocrine Carcinoma, Mixed Adenoneuroendocrine Carcinoma, and Adenocarcinoma
  12. 29712
    “…Tweet: Synbiotic prevents nosocomial infection in critically ill adults, while total parenteral nutrition has the adverse curative.…”
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    Synbiotic Therapy Prevents Nosocomial Infection in Critically Ill Adult Patients: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials Based on a Bayesian Framework
  13. 29713
    “…RESULTS: Ninety colorectal cancer resections were performed with curative intent from June 2018 to June 2020. Thirty robotic colorectal cancer resections (RCcR) were performed after adaption of programme and were compared with 60 non-robotic colorectal cancer resections (N-RCcR) prior to implementation of technique. …”
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    Effective implementation and adaptation of structured robotic colorectal programme in a busy tertiary unit
  14. 29714
    “…Traditional therapeutic approaches, such as sclerotherapy and surgical debulking, are often not curative in PROS patients, leading to a recrudescence of the overgrowth in the treated area. …”
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    PIK3CA-Related Overgrowth Spectrum From Diagnosis to Targeted Therapy: A Case of CLOVES Syndrome Treated With Alpelisib
  15. 29715
    “…Methods: The protocol-based, international IMIGASTRIC (International study group on Minimally Invasive surgery for Gastric Cancer) registry was queried to retrieve data on patients undergoing laparoscopic or open gastrectomy with D2 lymphadenectomy for gastric cancer with curative intent from January 2000 to December 2014. …”
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    Laparoscopic Compared with Open D2 Gastrectomy on Perioperative and Long-Term, Stage-Stratified Oncological Outcomes for Gastric Cancer: A Propensity Score-Matched Analysis of the IMIGASTRIC Database
  16. 29716
    Publicado 2021
    “…METHODS: This international, prospective, cohort study enrolled 20 006 adult (≥18 years) patients from 466 hospitals in 61 countries with 15 cancer types, who had a decision for curative surgery during the COVID-19 pandemic and were followed up until the point of surgery or cessation of follow-up (Aug 31, 2020). …”
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    Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study
  17. 29717
    “…We reviewed medical records and collected clinicopathologic factors for OPC patients treated with curative intent RT. The Kaplan-Meier method was used to estimate time-to-event outcomes. …”
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    Oropharyngeal Cancer Early Outcomes and Challenges During the COVID-19 Pandemic
  18. 29718
    “…From 3/1/2020-1/29/2021, mean age was 4.9 y (range 5.5 m - 19.0 y), 41/78 (52.6%) were male, and 2/78 (2.6%) received 2 courses of RT under GA, for a total of 80 courses. 24/80 (30.0%) courses were delivered to the chest, abdomen, and/or pelvis, 21/80 (26.3%) craniospinal axis, 17/80 (21.3%) brain, 9/80 (11.3%) total body irradiation, 5/80 (6.3%) head/neck, and 4/80 (5%) other. 64/80 (80%) of courses were delivered with curative intent. 39/80 (48.8%) used proton therapy, 18/80 (22.5%) photons, and 23/80 (28.8%) both modalities. …”
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    General Anesthesia for Pediatric Radiotherapy in the Era of COVID-19
  19. 29719
    “…If the disease remains undiagnosed and untreated, progressive growth occurs, reminiscent of malignant tumours. The only curative therapy is complete resection, which is limited to localised stages, and palliative drug therapy is used otherwise. …”
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    Long-term follow-up of liver alveolar echinococcosis using echinococcosis multilocularis ultrasound classification
  20. 29720
    “…Une anticoagulation curative, une antibiothérapie par ceftriaxone et rovamycine ainsi que de la dexaméthasone étaient introduits. …”
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    Syndrome de Sweet secondaire à une infection sévère à SARS-CoV-2
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