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29721por Wang, Yao‐bin, Zhao, Xiao‐bing, Geng, Bin, Sheng, Xiao‐yun, Zhang, Kai, Cao, Chen, Xia, Ya‐yi, Chen, Shu‐lian“…Operation time, hospital stay, and complications were recorded for both groups. The curative effect was evaluated according to the Visual Analog Scale (VAS) of neck and arm pain, Japanese Orthopaedic Association (JOA) score, and modified MacNab scale. …”
Publicado 2021
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29722por Kendall, Emily A., Hussain, Hamidah, Kunkel, Amber, Kubiak, Rachel W., Trajman, Anete, Menzies, Richard, Drain, Paul K.“…Before initiating TPT, TB disease was excluded either through symptom-only screening or with additional radiographic screening that could detect subclinical TB but might limit access to the TPT intervention. TPT’s potential curative effects on both latent and subclinical TB were modeled, as were both acquisitions of resistance and prevention of drug-resistant disease. …”
Publicado 2021
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29723por Houston, Brendan J, Riera-Escamilla, Antoni, Wyrwoll, Margot J, Salas-Huetos, Albert, Xavier, Miguel J, Nagirnaja, Liina, Friedrich, Corinna, Conrad, Don F, Aston, Kenneth I, Krausz, Csilla, Tüttelmann, Frank, O’Bryan, Moira K, Veltman, Joris A, Oud, Manon S“…WIDER IMPLICATIONS: Our systematic review curates all currently available evidence to reveal the strength of GDRs in male infertility. …”
Publicado 2021
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29724por Iseas, Soledad, Sendoya, Juan M., Robbio, Juan, Coraglio, Mariana, Kujaruk, Mirta, Mikolaitis, Vanesa, Rizzolo, Mariana, Cabanne, Ana, Ruiz, Gonzalo, Salanova, Rubén, Gualdrini, Ubaldo, Méndez, Guillermo, Antelo, Marina, Carballido, Marcela, Rotondaro, Cecilia, Viglino, Julieta, Eleta, Martín, Di Sibio, Alejandro, Podhajcer, Osvaldo L., Roca, Enrique, Llera, Andrea S., Golubicki, Mariano, Abba, Martín Carlos“…Currently, there is a lack of reliable markers beyond TNM to deliver a personalized treatment in a cancer setting where the goal is a curative treatment. Here, we performed an integrated characterization of the predictive and prognostic role of clinical features, mismatch-repair deficiency markers, HER2, CDX2, PD-L1 expression, and CD3(−)CD8(+) tumor-infiltrating lymphocytes (TILs) coupled with targeted DNA sequencing of 76 non-metastatic RC patients assigned to total mesorectal excision upfront (TME; n = 15) or neoadjuvant chemo-radiotherapy treatment (nCRT; n = 61) followed by TME. …”
Publicado 2022
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29725por Wesseling-Rozendaal, Yvonne, van Doorn, Arie, Willard-Gallo, Karen, van de Stolpe, Anja“…SIMPLE SUMMARY: Immunotherapy enhances the immune response against cancer and is potentially curative. Unfortunately, few patients with breast cancer benefit from this therapy. …”
Publicado 2022
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29726por Chen, Po-Chuan, Yeh, Yu-Min, Lin, Bo-Wen, Chan, Ren-Hao, Su, Pei-Fang, Liu, Yi-Chia, Lee, Chung-Ta, Chen, Shang-Hung, Lin, Peng-Chan“…Results: A total of 1073 patients who received curative intent surgery at the National Cheng Kung University Hospital between January 2004 and January 2019 were included. …”
Publicado 2022
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29727por Duffy, Grant, Cheng, Paul P., Yuan, Neal, He, Bryan, Kwan, Alan C., Shun-Shin, Matthew J., Alexander, Kevin M., Ebinger, Joseph, Lungren, Matthew P., Rader, Florian, Liang, David H., Schnittger, Ingela, Ashley, Euan A., Zou, James Y., Patel, Jignesh, Witteles, Ronald, Cheng, Susan, Ouyang, David“…DESIGN, SETTINGS, AND PARTICIPANTS: This cohort study included physician-curated cohorts from the Stanford Amyloid Center and Cedars-Sinai Medical Center (CSMC) Advanced Heart Disease Clinic for cardiac amyloidosis and the Stanford Center for Inherited Cardiovascular Disease and the CSMC Hypertrophic Cardiomyopathy Clinic for hypertrophic cardiomyopathy from January 1, 2008, to December 31, 2020. …”
Publicado 2022
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29728por Grossmann, Nico C., Rajwa, Pawel, Quhal, Fahad, König, Frederik, Mostafaei, Hadi, Laukhtina, Ekaterina, Mori, Keiichiro, Katayama, Satoshi, Motlagh, Reza Sari, Fankhauser, Christian D., Mattei, Agostino, Moschini, Marco, Chlosta, Piotr, van Rhijn, Bas W.G., Teoh, Jeremy Y.C., Compérat, Eva, Babjuk, Marek, Abufaraj, Mohammad, Karakiewicz, Pierre I., Shariat, Shahrokh F., Pradere, Benjamin“…PATIENT SUMMARY: We compared cancer outcomes in different bladder cancer scenarios in a large, multinational series of patients who underwent removal of the bladder with curative intent. We found that patients who experienced recurrence of non–muscle-invasive bladder cancer (NMIBC) had similar survival outcomes to those with initial muscle-invasive bladder cancer (MIBC), while patients who experienced progression of NMIBC to MIBC had the worst outcomes. …”
Publicado 2022
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29729“…The former group was cured with electroacupuncture in the early stage, and the latter group was intervened on the basis of early electroacupuncture combined with the concept of ERAS. The curative effect, the time of getting out of bed for the first time after operation, the time of postoperative rehabilitation, postoperative rehabilitation cost, pain score and knee joint function score, range of motion (ROM) of knee joint, low shear of whole blood viscosity, plasma viscosity, fibrinogen level, and postoperative complications were compared. …”
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29730por Pagano, Duilio, Khouzam, Simone, Magro, Bianca, Barbara, Marco, Cintorino, Davide, di Francesco, Fabrizio, Li Petri, Sergio, Bonsignore, Pasquale, Calamia, Sergio, Deiro, Giacomo, Cammà, Calogero, Canzonieri, Marco, Gruttadauria, Salvatore“…Among the overall 111 patients with RHCC in the LRT group, 33 were iteratively treated with further curative treatment (12 were treated with LR, two with MWTA, three with a combined LR-MWTA treatment, and 16 underwent LT). …”
Publicado 2022
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29731Publicado 2022“…CONCLUSION: Preemptive/salvage therapy with VEN after allo-HSCT in patients with hematological malignancies is effective and well tolerated, monitoring the concentration of VEN is expected to improve the curative effect. The prognosis of patients who fail to reach the major responses after one course of preemptive/salvage treatment with VEN is poor, so they need to switch to other treatment schemes as soon as possible.…”
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29732por ZHANG, Huiwen, XIA, Huimin, LIU, Hong, LIU, Yanyan, JIU, Xin, ZHANG, Minhui, HE, Chunlong, WANG, Huanyun“…Clinically, Sanzi San is administered orally and distributed via blood to the action site, which implies that the absorption, distribution, metabolism, and excretion (ADME) are closely related to the pharmacological action and curative effect. Therefore, possible explanations for the material basis of Sanzi San were explored in this study preliminarily. …”
Publicado 2022
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29733por HUANG, Mengwen, WU, Huan, YU, Wei, WANG, Ying, WANG, Fengcan, ZHANG, Chunchun, ZHOU, Longsheng, LI, Zegeng“…QYSLD has been used to treat non-small cell lung cancer (NSCLC) for over 20 years in clinical practice, and its curative effect is considered credible. However, the chemical constituents of QYSLD have not been revealed because of their complexity, which has significantly hindered the systematic clarification of the efficacy of the materials and quality evaluation. …”
Publicado 2021
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29734“…This allows for the establishment, evaluation, and revision of preventive measures and curative services. The results of such monitoring should serve as a database for evidence-based mental health policy. …”
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29735por Fleischmann, Maximilian, Scholl, Sebastian, Frietsch, Jochen J., Hilgendorf, Inken, Schrenk, Karin, Hammersen, Jakob, Prims, Florian, Thiede, Christian, Hochhaus, Andreas, Schnetzke, Ulf“…Furthermore, VEN might play a role in a subgroup of patients with failure to conventional chemotherapy as a salvage regimen aiming for potential curative alloHSCT. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00432-022-03930-5.…”
Publicado 2022
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29736por Giosa, Domenico, Giuffrè, Letterio, Felice, Maria Rosa, Rigano, Gabriele, Lui, Maria, Cigliano, Riccardo Aiese, Bezerra, Leila M. Lopes, Romeo, Orazio“…The StringTie software was used to assemble the transcriptomes imported into the Apollo webtool to manually curate the genome annotation. Transcripts were investigated using TransDecoder and CPC2 programs to determine whether a gene was potentially protein-coding or non-coding. …”
Publicado 2022
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29737por Azar, Ibrahim, Yazdanpanah, Omid, Jang, Hyejeong, Austin, Adam, Kim, Seongho, Chi, Jie, Alkassis, Samer, Saha, Biplab K., Chopra, Amit, Neu, Kristoffer, Mehdi, Syed, Mamdani, Hirva“…The backbone of chemotherapy regimens in both is a platinum-etoposide doublet: cisplatin is traditionally the preferred platinum agent in the curative intent setting, whereas carboplatin is preferred in ES-SCLC because of its favorable toxicity profile. …”
Publicado 2022
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29738por Alhadlaq, Omar, Alnassar, Anhar A, Alsuhaibani, Rawan H, AlQuraa, Reem, Abothenain, Fayha, Afeef, Ahmed Bin, Altwaijry, Yasser A, Alzahrani, Ali S“…Surgery effectively reduces tumor size but is rarely curative and frequently complicated by hypopituitarism of variable severity and local complications. …”
Publicado 2022
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29739por Ferro, Alessandra, Sepulcri, Matteo, Schiavon, Marco, Scagliori, Elena, Mancin, Edoardo, Lunardi, Francesca, Gennaro, Gisella, Frega, Stefano, Dal Maso, Alessandro, Bonanno, Laura, Paronetto, Chiara, Caumo, Francesca, Calabrese, Fiorella, Rea, Federico, Guarneri, Valentina, Pasello, Giulia“…SIMPLE SUMMARY: Stage III non-small cell lung cancer (NSCLC) is a highly heterogeneous group of diseases with wide differences in tumor size and in nodal involvement and, although the intent of treatments is potentially curative, survival data still remain disappointing in some cases. …”
Publicado 2022
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29740por Tan, Darren Jun Hao, Ng, Cheng Han, Lin, Snow Yunni, Pan, Xin Hui, Tay, Phoebe, Lim, Wen Hui, Teng, Margaret, Syn, Nicholas, Lim, Grace, Yong, Jie Ning, Quek, Jingxuan, Xiao, Jieling, Dan, Yock Young, Siddiqui, Mohammad Shadab, Sanyal, Arun J, Muthiah, Mark D, Loomba, Rohit, Huang, Daniel Q“…There were no significant differences in treatment allocation (curative therapy, palliative therapy, and best supportive care) between patients with NAFLD-related hepatocellular carcinoma and those with hepatocellular carcinoma due to other causes. …”
Publicado 2022
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