“…We used Kaplan-Meier p-values, hazard ratios (HR), and concordance probability estimates (CPE) to assess prediction performance, comparing separate and integrated datasets. Data integration resulted in the best PFS signature (withheld data: p-value = 0.008; HR = 2.83; CPE = 0.72). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…It serves as a brucellosis knowledgebase and supports brucellosis data integration and automated reasoning.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: A major reason for adopting identifiers such as LSIDs is to facilitate data integration. We have demonstrated the incorporation of LSIDs into the Catalogue of Life, in a manner consistent with the biodiversity informatics community's conventions for LSID use. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Extensive and automated data integration in bioinformatics facilitates the construction of large, complex biological networks. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…As future work, we will expand the set of GIATE tools to continue to encourage its use by cancer researchers, and we will engineer an ontology to annotate GIATE elements and facilitate unambiguous interpretation and data integration.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Through the large-scale transcriptome sequencing as well as public EST data integration, we performed a comprehensive characterization of the A. japonicus transcriptome and identified candidate aestivation-related genes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We leverage developments in natural language parsing, rule languages and ontologies, and data integration technologies to assemble a prototype query processor that is able to transform a natural language query into a semantically equivalent structured query over the database. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Background  The recent emergence of the 2009 pandemic influenza A/H1N1 virus has highlighted the value of free and open access to influenza virus genome sequence data integrated with information about other important virus characteristics. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Recently, two promising simultaneous data integration methods have been proposed to attain this goal, namely generalized singular value decomposition (GSVD) and simultaneous component analysis with rotation to common and distinctive components (DISCO-SCA). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…With the recent success of genome-wide association studies (GWAS), a wealth of association data has been accomplished for more than 200 complex diseases/traits, proposing a strong demand for data integration and interpretation. A combinatory analysis of multiple GWAS datasets, or an integrative analysis of GWAS data and other high-throughput data, has been particularly promising. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Thus, the network-based data integration method provides a convergence between biological relevance and clinical usefulness in gene signature development.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…New experimental techniques coupled with powerful data integration methods now enable us to not only investigate what features govern protein stability in general, but also to build models that identify what properties determine each protein’s metabolic stability. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Comparisons to other unsupervised data integration techniques—as well as to non-integrative approaches—demonstrate that MDI is competitive, while also providing information that would be difficult or impossible to extract using other methods. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Robust transcriptional signatures in cancer can be identified by data similarity-driven meta-analysis of gene expression profiles. An unbiased data integration and interrogation strategy has not previously been available. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the example presented, data integration facilitates comprehensive and spatially explicit estimation of AGB for the entire study area.…”
Enlace del recurso
Enlace del recurso

“…Western-blotting was used to validate iTRAQ data. Integrated function and protein interactions were explored using WEB based bioinformatics tools (DAVID v6.7 and STRING v9.0). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, PAHKB provides online tools for data browsing and searching, data integration, pathway graphical presentation, and gene ranking. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…VDR focused research that complements publically available data (e.g., ENCODE Birney et al., 2007; Birney, 2012), TCGA (Strausberg et al., 2002), GTEx (Consortium, 2013) will enable these questions to be addressed through large-scale data integration efforts.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: We introduce optPBN, a Matlab-based toolbox for the optimisation of probabilistic Boolean networks (PBN) which operates under the framework of the BN/PBN toolbox. optPBN offers an easy generation of probabilistic Boolean networks from rule-based Boolean model specification and it allows for flexible measurement data integration from multiple experiments. Subsequently, optPBN generates integrated optimisation problems which can be solved by various optimisers. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The pipeline features functionalities such as pre-processing of raw data, integration of open source alignment tools (Bowtie2, BWA, Maq, NovoAlign and SOAP2), SNP prediction (SAMtools/SOAPsnp/CNS2snp and CbCC) methods and interfaces for developing genotyping assays. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso