“…The scPlant pipeline is implemented with numerous functions for diverse analytical tasks, ranging from basic data processing to advanced demands such as cell-type annotation and deconvolution, trajectory inference, cross-species data integration, and cell-type-specific gene regulatory network construction. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we propose SPIRAL, consisting of two consecutive modules: SPIRAL-integration, with graph domain adaptation-based data integration, and SPIRAL-alignment, with cluster-aware optimal transport-based coordination alignment. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We discuss the potential implications of multiomics data integration in the development of novel diagnostic tools, identification of therapeutic targets, and the prospects of precision medicine in acromegaly management. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…MitoP2 enables (i) the identification of putative orthologous proteins between these species to study evolutionarily conserved functions and pathways; (ii) the integration of data from systematic genome-wide studies such as proteomics and deletion phenotype screening; (iii) the prediction of novel mitochondrial proteins using data integration and the assignment of evidence scores; and (iv) systematic searches that aim to find the genes that underlie common and rare mitochondrial diseases. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Reconstruction of metabolic networks in SYSTOMONAS was achieved via comparative genomics. Broad data integration is realized using SOAP interfaces for the well established databases BRENDA, KEGG and PRODORIC. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We study the effect of different data integration methods, and based on the validation studies, we show that our approach, ToppGene , outperforms two of the existing candidate gene prioritization methods, SUSPECTS and ENDEAVOUR. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we highlight selected tools and resources for gene class level ontology analysis (Section 2), gene coexpression analysis (Section 3), gene network analysis (Section 4), biological pathway analysis (Section 5), analysis of transcriptional regulation (Section 6), and omics data integration (Section 7). The overall goal of this review is to provide researchers with tools and information to facilitate the interpretation of microarray data.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…HIV-1 integrase protein was used as a case study to show the utility of this application. We show how data integration facilitates identification of new questions and hypotheses much more rapid and convenient than current approaches using isolated repositories. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We also show how the obtained APPs of the network topology can be used in a Bayesian data integration strategy to integrate two different microarray data sets. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Patient investigators, community investigators, and academic investigators with diverse expertise will work together to meet project goals related to data integration, patient engagement and recruitment, and the development of streamlined regulatory policies. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Such a link enhances data integration and improves the scientific integrity of data.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Several bottlenecks slow-down the transition from conventional to personalized medicine: generation of cost-effective high-throughput data; hybrid education and multidisciplinary teams; data storage and processing; data integration and interpretation; and individual and global economic relevance. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The Disease Ontology (DO) enables cross-domain data integration through a common standard of human disease terms and their etiological descriptions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We also discuss the SemaGrow Stack, a query federation and data integration infrastructure used to estimate the semantic distance between crawled web resources and AGRIS.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…OncDRS enables seamless data integration, secure and self-navigated query and extraction of clinical and genomic data from heterogeneous sources. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: We describe a light-weight approach for the storage, analysis and distribution of relevant LDIR omics datasets. The data integration platform, called BRIDE, contains information from the literature as well as experimental information from transcriptomics and proteomics studies. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The web interface at (http://keypathwayminer.compbio.sdu.dk) implements all core functionalities of the KeyPathwayMiner tool set such as data integration, input of background knowledge, batch runs for parameter optimization and visualization of extracted pathways. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We anticipate MathIOmica to not only help in the creation of new bioinformatics tools, but also in promoting interdisciplinary investigations, particularly from researchers in mathematical, physical science and engineering fields transitioning into genomics, bioinformatics and omics data integration.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Through heterogeneous data integration we linked gene essentiality, persistence and expression variability. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…IMP incorporates robust read preprocessing, iterative co-assembly, analyses of microbial community structure and function, automated binning, as well as genomic signature-based visualizations. The IMP-based data integration strategy enhances data usage, output volume, and output quality as demonstrated using relevant use-cases. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso