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  1. 1401
    “…The authors also provide phenotypic data in a semantic form to facilitate data integration and accessibility across taxa and provide an updated phenotype bank of morphological characters for megaspilid taxonomic treatments. …”
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    Unique extrication structure in a new megaspilid, Dendrocerus scutellaris Trietsch & Mikó (Hymenoptera: Megaspilidae)
  2. 1402
    “…GourdBase consists of six main modules that store and interlink multi-omic data: the genome (with transcriptomic data integrated) module, the phenome module, the markers/QTLs module, the maps (genetic, physical and comparative) module, the cultivars module, and the publications module. …”
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    GourdBase: a genome-centered multi-omics database for the bottle gourd (Lagenaria siceraria), an economically important cucurbit crop
  3. 1403
    “…As other areas of biomedical sciences, including metabolomics, epigenomics and pharmacogenomics, are moving towards the omics scale, we are witnessing the rise of inter-disciplinary data integration strategies to support a better understanding of biological systems and eventually the development of successful precision medicine. …”
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    Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences
  4. 1404
    “…Haplosaurus computes protein haplotypes from pre-existing chromosomally-phased genomic variation data. Integration into the Ensembl resource provides rapid and detailed protein haplotypes retrieval. …”
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    Haplosaurus computes protein haplotypes for use in precision drug design
  5. 1405
    por Haux, Reinhold
    Publicado 2018
    “…Then the initiative’s four consortia DIFUTURE (Data Integration for Future Medicine), HiGHmed (Heidelberg-Göttingen-Hannover Medical Informatics), MIRACUM (Medical Informatics in Research and Care in University Medicine), and SMITH (Smart Medical Information Technology for Healthcare) present their concepts and plans. …”
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    Health Information Systems – from Present to Future?: The German Medical Informatics Initiative
  6. 1406
    “…To help realize the potential of multi-modal data integration for the study of mental illness, the Centre for Addiction and Mental Health (CAMH) constructed a centralized data capture, visualization and analytics environment—the CAMH Neuroinformatics Platform—based on the Ontario Brain Institute (OBI) Brain-CODE architecture, towards the curation of a standardized, consolidated psychiatric hospital-wide research dataset, directly coupled to high performance computing resources.…”
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    The CAMH Neuroinformatics Platform: A Hospital-Focused Brain-CODE Implementation
  7. 1407
    “…Here, clinical MOZ expression analysis combined with data integration from the TCGA and GEO databases indicated that a low level of MOZ was associated with poor prognosis. …”
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    MOZ Forms an Autoregulatory Feedback Loop with miR-223 in AML and Monocyte/Macrophage Development
  8. 1408
    “…Systems biology and innovative data integration can provide fresh insights into the molecular ontogeny of the first week of life, a dynamic developmental phase that is key for health and disease.…”
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    Dynamic molecular changes during the first week of human life follow a robust developmental trajectory
  9. 1409
    “…The vision of precision medicine relies on the integration of large-scale clinical, molecular and environmental datasets. Data integration may be thought of along two axes: data fusion across institutions, and data fusion across modalities. …”
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    Merging heterogeneous clinical data to enable knowledge discovery
  10. 1410
    por Dhombres, Ferdinand, Charlet, Jean
    Publicado 2019
    “…The research areas in 2018 were mainly related to the ontology-based data integration for phenotype-genotype association mining, the design of ontologies and their application, and the semantic annotation of clinical texts. …”
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    Formal Medical Knowledge Representation Supports Deep Learning Algorithms, Bioinformatics Pipelines, Genomics Data Analysis, and Big Data Processes: Findings from the 2019 IMIA Yearbook Section on Knowledge Representation and Management
  11. 1411
    “…This work sheds light on the overall organization of the full-length protein combining solution scattering data, integrative modeling, and single-molecule experiments. …”
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    KAP1 is an antiparallel dimer with a functional asymmetry
  12. 1412
    “…To improve our understanding of this plasticity, we performed a high-level data integration of 14 whole-genome transcriptomics datasets from samples of intestinal mouse mucosa. …”
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    High-level integration of murine intestinal transcriptomics data highlights the importance of the complement system in mucosal homeostasis
  13. 1413
    “…Maximizing the impact and value of scientific research requires efficient knowledge distribution, which increasingly depends on the integration of standardized published data into online databases. To make data integration more comprehensive and efficient for fission yeast research, PomBase has pioneered a community curation effort that engages publication authors directly in FAIR-sharing of data representing detailed biological knowledge from hypothesis-driven experiments. …”
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    Community curation in PomBase: enabling fission yeast experts to provide detailed, standardized, sharable annotation from research publications
  14. 1414
    “…Semantic technologies and linked data provide a possibility for data integration and for automatic information extraction. …”
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    Towards the Integration of Agricultural Data from Heterogeneous Sources: Perspectives for the French Agricultural Context Using Semantic Technologies
  15. 1415
    “…We identified the co-evolved protein network and pinpointed a list of drugs that target this network by using data integration from different sources. Our computational analysis found widely used drugs such as nonsteroidal anti-inflammatory drugs and vasodilators. …”
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    ACE2 Co-evolutionary Pattern Suggests Targets for Pharmaceutical Intervention in the COVID-19 Pandemic
  16. 1416
    “…A huge amount of atomized biological data collected in various databases and the need for a description of their relation by theoretical methods causes the development of data integration methods. The omics data analysis by integration of biological knowledge with mathematical procedures implemented in the OmicsON R library is presented in the paper. …”
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    OmicsON – Integration of omics data with molecular networks and statistical procedures
  17. 1417
    “…To realize the potential power of RWD and RWE, challenges related to data integration, access, interoperability, standardization of analytical methods, quality control, security, privacy protection, and ethical standards for data use must be addressed. …”
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    Harnessing real-world evidence to reduce the burden of noncommunicable disease: health information technology and innovation to generate insights
  18. 1418
    “…In this study, bacterial 16S rRNA-gene sequencing, untargeted metabolomics (gas chromatography-mass spectrometry) and data integration analyses were used to characterize and differentiate commercial Cheddar cheeses of varying maturity made by the same and different manufacturers. …”
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    Microbiota and Metabolite Profiling Combined With Integrative Analysis for Differentiating Cheeses of Varying Ripening Ages
  19. 1419
    “…We highlight the importance of computational modeling and data integration to derive an actionable understanding of RAS signaling that will allow us to design new mechanism-based therapies for RAS mutated cancers.…”
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    The Ins and Outs of RAS Effector Complexes
  20. 1420
    “…In this work, we applied data integration methods to develop a Unified Knowledge Space (UKS) and used it to identify a new set of genes associated with SARS-CoV-2 host response, both in vitro and in vivo. …”
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    Integrated network analysis reveals new genes suggesting COVID-19 chronic effects and treatment
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