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1501por Qiu, Xintao, Boufaied, Nadia, Hallal, Tarek, Feit, Avery, de Polo, Anna, Luoma, Adrienne M., Alahmadi, Walaa, Larocque, Janie, Zadra, Giorgia, Xie, Yingtian, Gu, Shengqing, Tang, Qin, Zhang, Yi, Syamala, Sudeepa, Seo, Ji-Heui, Bell, Connor, O’Connor, Edward, Liu, Yang, Schaeffer, Edward M., Jeffrey Karnes, R., Weinmann, Sheila, Davicioni, Elai, Morrissey, Colm, Cejas, Paloma, Ellis, Leigh, Loda, Massimo, Wucherpfennig, Kai W., Pomerantz, Mark M., Spratt, Daniel E., Corey, Eva, Freedman, Matthew L., Shirley Liu, X., Brown, Myles, Long, Henry W., Labbé, David P.“…Analyses of clinical specimens reveal that concurrent low AR and high MYC transcriptional programs accelerate prostate cancer progression toward a metastatic, castration-resistant disease. Data integration of single-cell transcriptomics together with ChIP-seq uncover an increase in RNA polymerase II (Pol II) promoter-proximal pausing at AR-dependent genes following MYC overexpression without an accompanying deactivation of AR-bound enhancers. …”
Publicado 2022
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1502por Wallace, Kristi L., Bursik, Marcus I., Kuehn, Stephen, Kurbatov, Andrei V., Abbott, Peter, Bonadonna, Costanza, Cashman, Katharine, Davies, Siwan M., Jensen, Britta, Lane, Christine, Plunkett, Gill, Smith, Victoria C., Tomlinson, Emma, Thordarsson, Thor, Walker, J. Douglas“…Nonetheless, the study of tephra deposits is challenged by a lack of standardization that inhibits data integration across geographic regions and disciplines. …”
Publicado 2022
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1503por Mateescu, Bogdan, Jones, Jennifer C., Alexander, Roger P., Alsop, Eric, An, Ji Yeong, Asghari, Mohammad, Boomgarden, Alex, Bouchareychas, Laura, Cayota, Alfonso, Chang, Hsueh-Chia, Charest, Al, Chiu, Daniel T., Coffey, Robert J., Das, Saumya, De Hoff, Peter, deMello, Andrew, D’Souza-Schorey, Crislyn, Elashoff, David, Eliato, Kiarash R., Franklin, Jeffrey L., Galas, David J., Gerstein, Mark B., Ghiran, Ionita H., Go, David B., Gould, Stephen, Grogan, Tristan R., Higginbotham, James N., Hladik, Florian, Huang, Tony Jun, Huo, Xiaoye, Hutchins, Elizabeth, Jeppesen, Dennis K., Jovanovic-Talisman, Tijana, Kim, Betty Y.S., Kim, Sung, Kim, Kyoung-Mee, Kim, Yong, Kitchen, Robert R., Knouse, Vaughan, LaPlante, Emily L., Lebrilla, Carlito B., Lee, L. James, Lennon, Kathleen M., Li, Guoping, Li, Feng, Li, Tieyi, Liu, Tao, Liu, Zirui, Maddox, Adam L., McCarthy, Kyle, Meechoovet, Bessie, Maniya, Nalin, Meng, Yingchao, Milosavljevic, Aleksandar, Min, Byoung-Hoon, Morey, Amber, Ng, Martin, Nolan, John, De Oliveira Junior, Getulio P., Paulaitis, Michael E., Phu, Tuan Anh, Raffai, Robert L., Reátegui, Eduardo, Roth, Matthew E., Routenberg, David A., Rozowsky, Joel, Rufo, Joseph, Senapati, Satyajyoti, Shachar, Sigal, Sharma, Himani, Sood, Anil K., Stavrakis, Stavros, Stürchler, Alessandra, Tewari, Muneesh, Tosar, Juan P., Tucker-Schwartz, Alexander K., Turchinovich, Andrey, Valkov, Nedyalka, Van Keuren-Jensen, Kendall, Vickers, Kasey C., Vojtech, Lucia, Vreeland, Wyatt N., Wang, Ceming, Wang, Kai, Wang, ZeYu, Welsh, Joshua A., Witwer, Kenneth W., Wong, David T.W., Xia, Jianping, Xie, Ya-Hong, Yang, Kaichun, Zaborowski, Mikołaj P., Zhang, Chenguang, Zhang, Qin, Zivkovic, Angela M., Laurent, Louise C.“…ERCC2 investigators are also developing new bioinformatic pipelines to promote data integration through the exRNA atlas database. ERCC2 has established several Working Groups (Resource Sharing, Reagent Development, Data Analysis and Coordination, Technology Development, nomenclature, and Scientific Outreach) to promote collaboration between ERCC2 members and the broader scientific community. …”
Publicado 2022
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1504por Alharthi, Mariam K., Moria, Kawthar M., Alghazzawi, Daniyal M., Tayeb, Haythum O.“…This research aims to study the possibility of integrating local EEG signals from an epilepsy center in King Abdulaziz University hospital into the CHB-MIT dataset by applying a new compatibility framework for data integration. The framework comprises multiple functions, which include dominant channel selection followed by the implementation of a novel algorithm for reading XLtek EEG data. …”
Publicado 2022
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1505por Subramanian, Abhishek, Zakeri, Pooya, Mousa, Mira, Alnaqbi, Halima, Alshamsi, Fatima Yousif, Bettoni, Leo, Damiani, Ernesto, Alsafar, Habiba, Saeys, Yvan, Carmeliet, Peter“…We specifically highlight tools that use flexible, machine learning frameworks for large-scale data integration and gene prioritization. For each purpose-oriented category of tools, we describe underlying conceptual principles, highlight interesting applications and discuss limitations. …”
Publicado 2022
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1506por Balk, Meghan A., Deck, John, Emery, Kitty F., Walls, Ramona L., Reuter, Dana, LaFrance, Raphael, Arroyo-Cabrales, Joaquín, Barrett, Paul, Blois, Jessica, Boileau, Arianne, Brenskelle, Laura, Cannarozzi, Nicole R., Cruz, J. Alberto, Dávalos, Liliana M., de la Sancha, Noé U., Gyawali, Prasiddhi, Hantak, Maggie M., Hopkins, Samantha, Kohli, Brooks, King, Jessica N., Koo, Michelle S., Lawing, A. Michelle, Machado, Helena, McCrane, Samantha M., McLean, Bryan, Morgan, Michèle E., Pilaar Birch, Suzanne, Reed, Denne, Reitz, Elizabeth J., Sewnath, Neeka, Upham, Nathan S., Villaseñor, Amelia, Yohe, Laurel, Davis, Edward B., Guralnick, Robert P.“…FuTRES facilitates trait data integration and discoverability, accelerating new research agendas, especially scaling from intra- to interspecific trait variability.…”
Publicado 2022
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1507por Chernov, Andrey V., Savvas, Ilias K., Alexandrov, Alexander A., Kartashov, Oleg O., Polyanichenko, Dmitry S., Butakova, Maria A., Soldatov, Alexander V.“…In this research, an approach to intelligent decision making based on a data integration strategy to raise awareness of a controlled object is used. …”
Publicado 2022
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1508por Hoyt, Charles Tapley, Balk, Meghan, Callahan, Tiffany J., Domingo-Fernández, Daniel, Haendel, Melissa A., Hegde, Harshad B., Himmelstein, Daniel S., Karis, Klas, Kunze, John, Lubiana, Tiago, Matentzoglu, Nicolas, McMurry, Julie, Moxon, Sierra, Mungall, Christopher J., Rutz, Adriano, Unni, Deepak R., Willighagen, Egon, Winston, Donald, Gyori, Benjamin M.“…The standardized identification of biomedical entities is a cornerstone of interoperability, reuse, and data integration in the life sciences. Several registries have been developed to catalog resources maintaining identifiers for biomedical entities such as small molecules, proteins, cell lines, and clinical trials. …”
Publicado 2022
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1509por Lavery, Jessica A, Brown, Samantha, Curry, Michael A, Martin, Axel, Sjoberg, Daniel D, Whiting, Karissa“…Due to the inherently complex structure of the multiple phenomic and genomic datasets, the use of these data requires a robust process for data integration and preparation in order to build analytic models. …”
Publicado 2022
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1510por Yu, Yue, Jiang, Guoqian, Brandt, Eric, Forsyth, Tom, Dhruva, Sanket S, Zhang, Shumin, Chen, Jiajing, Noseworthy, Peter A, Doshi, Amit A, Collison-Farr, Kimberly, Kim, Dure, Ross, Joseph S, Coplan, Paul M, Drozda, Joseph P“…Our efforts provided useful insights in real-world data integration using OMOP CDM for medical device evaluation coordinated across multiple healthcare systems.…”
Publicado 2023
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1511“…Fed-GLMM can be applied to both federated and centralized research networks to enable privacy-preserving data integration and improve computational efficiency. …”
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1512por Skaburskas, K, Estrella, F, Shade, J, Manset, D, Revillard, J, Rios, A, Anjum, A, Branson, A, Bloodsworth, P, Hauer, T, McClatchey, R, Rogulin, D“…This paper discusses some of the major challenges in bio-medical data integration and indicates how these will be resolved in the HeC system. …”
Publicado 2008
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1513“…The contributions cover a wide spectrum of topics in the database and information systems field, including: database foundation and theory, data modeling and database design, business process modeling, query optimization in relational and object databases, materialized view selection algorithms, index data structures, distributed systems, system and data integration, semi-structured data and databases, semantic data management, information retrieval, data mining techniques, data stream processing, trust and reputation in the Internet, and social networks. …”
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1514“…The first step in the data integration process is the standardisation of the declaration of the various data points whether these are alarms, equipment statuses or analogue measurement values. …”
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1515“…Towards that goal, we recently constructed PathSys, a data integration platform for systems biology, which provides dynamic integration over a diverse set of databases [Baitaluk et al. (2006) BMC Bioinformatics 7, 55]. …”
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1516“…In fact, the complex nature of cancer biology is the reason why we need tools for data integration. Given the complexity of managing multiple technologies and dataset formats, several projects have been introduced including cancer Biomedical Informatics Grid (caGRID) and the Biomedical Research Institute Domain Group (BRIDG) with limited applicability. …”
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1517por Hall, Thomas J., Mullen, Michael P., McHugo, Gillian P., Killick, Kate E., Ring, Siobhán C., Berry, Donagh P., Correia, Carolina N., Browne, John A., Gordon, Stephen V., MacHugh, David E.“…These six gene sets were integrated with three bTB breed GWAS data sets by employing a new genomics data integration tool—gwinteR. Using GWAS summary statistics, this methodology enabled detection of 36, 102 and 921 prioritised SNPs for Charolais, Limousin and Holstein-Friesian, respectively. …”
Publicado 2021
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1518por Escobar-Viera, César, Coulter, Robert W S, Friedman, M Reuel, Thoma, Brian, Switzer, Galen E, Martina, Jamie, Egan, James Erin, Primack, Brian“…At all stages, we will assess the fit of data integration as recommended by the principles of best practice for mixed methods research in psychology. …”
Publicado 2023
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1519por Touré, Vasundra, Krauss, Philip, Gnodtke, Kristin, Buchhorn, Jascha, Unni, Deepak, Horki, Petar, Raisaro, Jean Louis, Kalt, Katie, Teixeira, Daniel, Crameri, Katrin, Österle, Sabine“…As a result, the SPHN Resource Description Framework (RDF) schema was implemented together with a data ecosystem that encompasses data integration, validation tools, analysis helpers, training and documentation for representing health metadata and data in a consistent manner and reaching nationwide data interoperability goals. …”
Publicado 2023
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1520“…In this paper, we applied GS to winter wheat data integrating two types of inputs: genomic and phenotypic. …”
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