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  1. 1721
    “…The detection of known marker genes confirms the successful capture and sequencing of samples composed of a mixed population of sporozoites. Using data integration, clustering, and trajectory analyses, we reveal differences in gene expression profiles of individual sporozoites, and identify both annotated and unannotated markers associated with sporozoite development. …”
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    Single-cell RNA sequencing reveals developmental heterogeneity among Plasmodium berghei sporozoites
  2. 1722
    “…Extensive taxonomic and gene annotations are stored in Gene Information Tables (GITs), a simple tractable data integration format useful for analysis through command line or for database management. …”
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    KAUST Metagenomic Analysis Platform (KMAP), enabling access to massive analytics of re-annotated metagenomic data
  3. 1723
    “…Over the past decade, traditional Chinese medicine (TCM) has widely embraced systems biology and its various data integration approaches to promote its modernization. …”
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    A comprehensive review of integrative pharmacology-based investigation: A paradigm shift in traditional Chinese medicine
  4. 1724
    “…One central task of developing nonvolatile phase change memory (PCM) is to improve its scalability for high‐density data integration. In this work, by first‐principles molecular dynamics, to date the thinnest PCM material possible (0.8 nm), namely, a monolayer Sb(2)Te(3), is proposed. …”
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    Phase‐Change‐Memory Process at the Limit: A Proposal for Utilizing Monolayer Sb(2)Te(3)
  5. 1725
    “…Measuring the mass flow of sugarcane in real-time is essential for harvester automation and crop monitoring. Data integration from multiple sensors should be an alternative to receive more reliable, accurate, and valuable predictions than data delivered by a single sensor. …”
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    Sensor Fusion with NARX Neural Network to Predict the Mass Flow in a Sugarcane Harvester
  6. 1726
    “…Current trends in biomedical research indicate data integration as a fundamental step towards precision medicine. …”
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    Analysing omics data sets with weighted nodes networks (WNNets)
  7. 1727
    “…The study of such machinery at the global scale has been challenged by the lack of data integration. Here, we report three regulatory network models for C. glutamicum: strong (3040 interactions) constructed solely with regulations previously supported by directed experiments; all evidence (4665 interactions) containing the strong network, regulations previously supported by nondirected experiments, and protein–protein interactions with a direct effect on gene transcription; sRNA (5222 interactions) containing the all evidence network and sRNA-mediated regulations. …”
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    Corynebacterium glutamicum Regulation beyond Transcription: Organizing Principles and Reconstruction of an Extended Regulatory Network Incorporating Regulations Mediated by Small RNA and Protein–Protein Interactions
  8. 1728
    “…Besides, it offers robust data integration on the surface and the devices required for Industry 4.0 during the COVID-19 pandemic. …”
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    SDN–IoT empowered intelligent framework for industry 4.0 applications during COVID-19 pandemic
  9. 1729
    “…CONCLUSION: Our method's successful application to an independent omics dataset confirmed that the novel CoNI framework is a transferable, entirely data-driven, flexible, and versatile tool for multiple omics data integration and interpretation.…”
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    Correlation guided Network Integration (CoNI) reveals novel genes affecting hepatic metabolism
  10. 1730
    “…While SQL (Structured Query Language) databases are popular in the biomedical domain, NoSQL database technologies have been used as a more relationship-based, flexible and scalable method of data integration. RESULTS: We have created a graph database integrating data from multiple sources. …”
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    LinkedImm: a linked data graph database for integrating immunological data
  11. 1731
    “…CONCLUSION: Six modules are displayed in AprGPD, including species, germplasm, genome, variation, product, tools. The data integrated by AprGPD will be helpful for the molecular breeding of apricot. …”
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    AprGPD: the apricot genomic and phenotypic database
  12. 1732
    “…We developed MicrobeTrace to facilitate rapid public health responses by overcoming barriers to data integration and exploration in molecular epidemiology. …”
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    MicrobeTrace: Retooling molecular epidemiology for rapid public health response
  13. 1733
    “…Additional new features are improved genomic sequence data, integrated NCBI TaxIDs and links to BacMedia, the new sister database on cultivation media. …”
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    BacDive in 2022: the knowledge base for standardized bacterial and archaeal data
  14. 1734
    “…In silico medicine may challenge some key principles: transparency and fairness of data usage; data privacy and protection across platforms and systems; data availability and quality; data integration and interoperability; intellectual property; data sharing; equal accessibility for persons and populations. …”
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    Health Technology Assessment for In Silico Medicine: Social, Ethical and Legal Aspects
  15. 1735
    “…Innovative strategies linking genome-wide interrogation with multi-layered metabolic data integration can accelerate the early steps of drug development, particularly target selection. …”
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    Pathway Driven Target Selection in Klebsiella pneumoniae: Insights Into Carbapenem Exposure
  16. 1736
    “…This work well demonstrates the necessary for data integration at the wastewater–medical service nexus and highlights an unusual role of the effluents from hospital sewage treatment facilities in revealing the status of fighting the pandemic, which helps to control the pandemic.…”
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    Hospital sewage treatment facilities witness the fighting against the COVID-19 pandemic
  17. 1737
    “…We discuss examples involving pesticide use in Europe to explore the associated challenges in implementing this framework (e.g., identifying relevant chemicals, conducting analyses at appropriate spatiotemporal scales) and ways forward (e.g., chemical prioritization approaches, data integration). The proposed framework is the first step toward understanding where and how much chemical pressure exceeds related ecological limits and which sources and actors are contributing to the chemical pressure. …”
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    Toward Assessing Absolute Environmental Sustainability of Chemical Pollution
  18. 1738
    “…Available experimental approaches are insufficient to properly analyse this complex system, and computational predictions and targeted data integration are needed as an alternative approach. …”
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    Mapping the epithelial–immune cell interactome upon infection in the gut and the upper airways
  19. 1739
    “…Here we generate an integrative high-resolution map of human cardiac remodelling after myocardial infarction using single-cell gene expression, chromatin accessibility and spatial transcriptomic profiling of multiple physiological zones at distinct time points in myocardium from patients with myocardial infarction and controls. Multi-modal data integration enabled us to evaluate cardiac cell-type compositions at increased resolution, yielding insights into changes of the cardiac transcriptome and epigenome through the identification of distinct tissue structures of injury, repair and remodelling. …”
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    Spatial multi-omic map of human myocardial infarction
  20. 1740
    por Alluhaidan, Ala Saleh
    Publicado 2022
    “…E-health security is a holistic notion that encompasses available medical data's integrities and confidentiality which ensures that data are not accessed by unauthorized people and allow doctors to offer proper treatment. …”
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    Secure Medical Data Model Using Integrated Transformed Paillier and KLEIN Algorithm Encryption Technique with Elephant Herd Optimization for Healthcare Applications
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