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1741por Agamah, Francis E., Bayjanov, Jumamurat R., Niehues, Anna, Njoku, Kelechi F., Skelton, Michelle, Mazandu, Gaston K., Ederveen, Thomas H. A., Mulder, Nicola, Chimusa, Emile R., 't Hoen, Peter A. C.“…We provide insight into the most appropriate methods and tools for research questions as showcased around the aetiology and treatment of COVID-19 that can be informed by multi-omics data integration. We conclude with an overview of challenges associated with multi-omics network-based analysis, such as reproducibility, heterogeneity, (biological) interpretability of the results, and we highlight some future directions for network-based integration.…”
Publicado 2022
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1742por Conde, Daniel, Triozzi, Paolo M., Pereira, Wendell J., Schmidt, Henry W., Balmant, Kelly M., Knaack, Sara A., Redondo-López, Arturo, Roy, Sushmita, Dervinis, Christopher, Kirst, Matias“…Motivated by the high similarities between Populus and Arabidopsis cell population in the vegetative apex, we applied a pipeline for interspecific single-cell gene expression data integration. We contrasted the developmental trajectories of primary phloem and xylem formation in both species, establishing the first comparison of vascular development between a model annual herbaceous and a woody perennial plant species. …”
Publicado 2022
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1743“…Survey data were analysed descriptively, and reflexive thematic analysis was performed on qualitative data. Mixed‐methods data integration produced four key student priorities for well‐being resources – ease of access, inclusive and preventative approach, sense of community and a safe space, and applying skills to real‐life contexts. …”
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1744“…Thus, we propose that increased use of ψ(w) as a fundamental descriptor of plant water status can enhance the insight gained from many drought-related experiments and facilitate data integration and sharing across laboratories and research disciplines.…”
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1745por El Serafy, Ghada Y.H., Schaeffer, Blake A., Neely, Merrie-Beth, Spinosa, Anna, Odermatt, Daniel, Weathers, Kathleen C., Baracchini, Theo, Bouffard, Damien, Carvalho, Laurence, Conmy, Robyn N., De Keukelaere, Liesbeth, Hunter, Peter D., Jamet, Cédric, Joehnk, Klaus D., Johnston, John M., Knudby, Anders, Minaudo, Camille, Pahlevan, Nima, Reusen, Ils, Rose, Kevin C., Schalles, John, Tzortziou, Maria“…In this paper, data sources and existing data integration frameworks are reviewed to give an overview of the present status and identify the gaps in existing frameworks. …”
Publicado 2021
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1746por Rafikova, Guzel, Piatnitskaia, Svetlana, Shapovalova, Elena, Chugunov, Svyatoslav, Kireev, Victor, Ialiukhova, Daria, Bilyalov, Azat, Pavlov, Valentin, Kzhyshkowska, Julia“…We discussed the approaches for ceramic implant modification and pointed out the need for data integration using mathematic modelling of the multiple ceramic implant characteristics and their contribution for long-term implant bio- and immuno-compatibility.…”
Publicado 2023
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1747por Dutta, Irene“…We also used the χ2 algorithm on the data (integrated luminosity of35.9 fb−1 ) and were able to exclude T quark masses below 1095 GeV with 95% CL.1…”
Publicado 2017
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1748“…The proposed approach bridges feature-based camera tracking and volumetric-based data integration together and has a good reconstruction performance in terms of both robustness and efficiency. …”
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1749“…State-of-the-art social sensing still suffers from severe privacy threats since it collects users’ personal data and disclosure behaviors, which could raise user privacy concerns due to data integration for personalization. In this paper, we propose a trust-aware model, called the User and Item Similarity Model with Trust in Diverse Kinds (UISTD), to enhance the personalization of social sensing while reducing users’ privacy concerns. …”
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1750“…The ‘omics movement, alongside increased throughput resulting from statistical and computational advances, has transformed our understanding of disease mechanisms and the multi-dimensional interaction between environmental stressors and host physiology through data integration into multi-dimensional analyses, i.e., integrative interactomics. …”
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1751“…Yet, alongside, emerges a problem of risks related to data integration techniques. The latter are not so widely taken account of. …”
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1752“…We validated scMultiSim’s simulated biological effects and demonstrated its applications by benchmarking a wide range of computational tasks, including cell clustering and trajectory inference, multi-modal and multi-batch data integration, RNA velocity estimation, GRN inference and CCI inference using spatially resolved gene expression data. …”
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1753“…CONCLUSIONS: A novel business‐oriented solution based on machine learning requires interprofessional integration, new professional roles, infrastructure improvement, and data integration to be effectively implemented. IMPLICATIONS FOR NURSING MANAGEMENT: Lessons learned from this study suggest the need to involve nurses in the early stages of the design of new machine‐learning technologies and the importance of training nurses on sepsis management through the support of disruptive technological innovation.…”
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1754por Venturini, Elisa, Svensson, Sarah L, Maaß, Sandra, Gelhausen, Rick, Eggenhofer, Florian, Li, Lei, Cain, Amy K, Parkhill, Julian, Becher, Dörte, Backofen, Rolf, Barquist, Lars, Sharma, Cynthia M, Westermann, Alexander J, Vogel, Jörg“…Our study highlights the power of interpreting available ‘omics’ datasets with a focus on small proteins, and may serve as a blueprint for a data integration-based survey of small proteins in diverse bacteria.…”
Publicado 2020
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1755por Garduno, Alexis, Cusack, Rachael, Leone, Marc, Einav, Sharon, Martin-Loeches, Ignacio“…The current narrative review seeks to highlight the potential application of multi-omics data integration and immunological profiling at the single-cell level to define endotypes in sepsis and septic shock. …”
Publicado 2023
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1756por Scaramozzino, Marco Umberto, Levi, Guido, Sapone, Giovanni, Romeo Plastina, Ubaldo“…In the case we present, data integration allowed us to make the right diagnosis, avoid invasive procedures, and reduce the costs for the national health system; we show that integrating technologies can improve the diagnosis of restrictive lung disease. …”
Publicado 2023
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1757por Husereau, Don, Villalba, Eva, Muthu, Vivek, Mengel, Michael, Ivany, Craig, Steuten, Lotte, Spinner, Daryl S., Sheffield, Brandon, Yip, Stephen, Jacobs, Philip, Sullivan, Terrence, Arshoff, Larry“…The important gaps to be filled are the need for linked information systems and data integration; evaluative processes that are timely and transparent; navigational tools for care providers; dedicated funding to facilitate rapid onboarding and support test development and proficiency testing; and broader engagement with innovation stakeholders beyond care providers and patients. …”
Publicado 2023
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1758por Di Giacomo, Melisa, Vega, Tatiana Alejandra, Cambiaso, Vladimir, Picardi, Liliana Amelia, Rodríguez, Gustavo Rubén, Pereira da Costa, Javier Hernán“…In this study, we provide insights into the effects of several genes underlying tomato ripening with potential impact on fruit shelf life. Data integration contributed to unraveling ripening-related genes, providing opportunities for assisted breeding.…”
Publicado 2023
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1759por Zhang, Xiao-Xi, Jin, Yin-Zi, Lu, Yi-Han, Huang, Lu-Lu, Wu, Chuang-Xin, Lv, Shan, Chen, Zhuo, Xiang, Hao, Zhou, Xiao-Nong“…Overall, a systematic redesign should be considered to enhance the resilience of health systems, which warrants a great need to sustain capacity-building efforts in emergency preparedness and response and raises an emerging concern of data integration in the concept of One Health that aims to address shared health threats at the human-animal-environment interface. …”
Publicado 2023
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1760“…Descriptive statistics, inferential analysis and thematic analysis will be used to analyse the data. Integration of quantitative and qualitative data will be used to provide a comprehensive understanding of the data. …”
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