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  1. 1761
    “…METHODS: We applied DeepBiomarker2 through data integration of multimodal information: lab test, medication, co-morbidities, and social determinants of health. …”
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    Prediction of Adverse Events Risk in Patients with Comorbid Post- Traumatic Stress Disorder and Alcohol Use Disorder Using Electronic Medical Records by Deep Learning Models
  2. 1762
    “…In describing the latest version 5.0 of PaxDb, we particularly emphasize the data integration from various types of raw data and how we expanded the number of organisms and tissue groups as well as the proteome coverage. …”
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    PaxDb 5.0: Curated Protein Quantification Data Suggests Adaptive Proteome Changes in Yeasts
  3. 1763
    “…Here, we benchmark 28 combinations of gene homology mapping methods and data integration algorithms in a variety of biological settings. …”
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    Benchmarking strategies for cross-species integration of single-cell RNA sequencing data
  4. 1764
    “…Several proteomics and transcriptomics studies have identified potential markers and altered biological pathways; however, comprehensive exploration and data integration can help to achieve an in-depth understanding of the altered pathobiology. …”
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    Integrated Meta-Omics Analysis Unveils the Pathways Modulating Tumorigenesis and Proliferation in High-Grade Meningioma
  5. 1765
    “…Further, systematic data integration and experimental validation platforms to prioritize brain transcriptional perturbations as therapeutic targets in PSP are currently lacking. …”
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    Cross species systems biology discovers glial DDR2, STOM, and KANK2 as therapeutic targets in progressive supranuclear palsy
  6. 1766
    “…In this project, we demonstrate the use of graph theory for data integration via individual networks where nodes and edges are individual-specific. …”
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    Graph-based multi-modality integration for prediction of cancer subtype and severity
  7. 1767
    “…Future directions include systematic searches to fully identify physiological data. Following data integration as mathematical equations, this holds the promise to improve postpartum, lactation and infant PBPK models.…”
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    Challenges Related to Acquisition of Physiological Data for Physiologically Based Pharmacokinetic (PBPK) Models in Postpartum, Lactating Women and Breastfed Infants—A Contribution from the ConcePTION Project
  8. 1768
    “…Technical issues like data integration, missing value imputation, batch effect correction and the exploration of inter-connections amongst these technical issues, can produce errors but are not well studied. …”
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    MultiPro: DDA-PASEF and diaPASEF acquired cell line proteomic datasets with deliberate batch effects
  9. 1769
    “…Together, OncoDB.HCC graphically presents comprehensive HCC data integration, reveals important HCC genes and loci for positional cloning and functional studies, and discloses potential molecular targets for improving HCC diagnosis and therapy.…”
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    OncoDB.HCC: an integrated oncogenomic database of hepatocellular carcinoma revealed aberrant cancer target genes and loci
  10. 1770
    “…METHODS: The literature was systematically reviewed between 1995–2005 to identify articles mentioning patient records, computers and data integration or sharing. RESULTS: Of 3124 articles, 84 were included describing 56 distinct projects. …”
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    Reviewing the integration of patient data: how systems are evolving in practice to meet patient needs
  11. 1771
    “…The predicted translational products of each genome have been clustered into groups of potential orthologues using Markov Chain Clustering and the data integrated into the e-Fungi object-oriented data warehouse (http://www.e-fungi.org.uk/). …”
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    Comparative Genome Analysis of Filamentous Fungi Reveals Gene Family Expansions Associated with Fungal Pathogenesis
  12. 1772
    “…Our approach provides the basis for ontology-driven data integration for translational research on gene and protein expression data. …”
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    Ontology-driven indexing of public datasets for translational bioinformatics
  13. 1773
    “…Moreover, ERGR has data integration tools such as for data union and intersection, and candidate gene selection based on evidence in multiple datasets or organisms. …”
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    ERGR: An ethanol-related gene resource
  14. 1774
    “…Results: The Sleipnir C++ library implements a variety of machine learning and data manipulation algorithms with a focus on heterogeneous data integration and efficiency for very large biological data collections. …”
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    The Sleipnir library for computational functional genomics
  15. 1775
    “…Based on that, we designed a publicly available platform that aims to data integration, analysis, visualization and finally the reconstruction of mycobacterial transcriptional gene regulatory networks: MycoRegNet. …”
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    From Corynebacterium glutamicum to Mycobacterium tuberculosis—towards transfers of gene regulatory networks and integrated data analyses with MycoRegNet
  16. 1776
    “…Using four newly developed computational tools, including novel DOGMA sub-network analysis, we showed the benefits of three-level ome-data integration to uncover the global Snf1 kinase role in yeast. …”
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    Reconstruction of the yeast Snf1 kinase regulatory network reveals its role as a global energy regulator
  17. 1777
    “…Here, we describe AMSA, an annotated multiple sequence alignment format used to build a new generation of generalized profiles, the migration of ScanProsite to Vital-IT, a cluster of 633 CPUs, and the adoption of the Distributed Annotation System (DAS) to facilitate PROSITE data integration and interchange with other sources. The latest version of PROSITE (release 20.54, of 22 September 2009) contains 1308 patterns, 863 profiles and 869 ProRules. …”
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    PROSITE, a protein domain database for functional characterization and annotation
  18. 1778
    por Georgiou, Andrew
    Publicado 2011
    “…The Medinfo program covered all aspects of health informatics from traditional areas, such as hospital information systems, patient registries, nursing informatics, data integration, standards, interoperability issues and decision support, to innovative topics, such as translational bioinformatics, text mining, intelligent data analysis, emerging technologies, quality, social networking, workflow and organizational issues. …”
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    The 13(th) world congress on medical and health informatics, Cape Town, South Africa: Partnerships for effective e-Health solutions
  19. 1779
    “…Application of high-throughput analyses have generated large amounts of data and necessitated the development of computational approaches for data integration. Therefore, we also cover computer-aided network analyses to infer regulatory networks, and demonstrate how genome-scale data can be used to construct regulatory and metabolic systems models of Salmonella pathogenesis. …”
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    Technologies and Approaches to Elucidate and Model the Virulence Program of Salmonella
  20. 1780
    “…Underlying these spatio-specific functions of BCL11B in incisor development is the regulation of a large gene network comprised of genes encoding several members of the FGF and TGFβ superfamilies, Sprouty proteins, and Sonic hedgehog. Our data integrate BCL11B into these pathways during incisor development and reveal the molecular mechanisms that underlie phenotypes of both Bcl11b(−/−) and Sprouty mutant mice.…”
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    BCL11B Regulates Epithelial Proliferation and Asymmetric Development of the Mouse Mandibular Incisor
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