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  1. 253921
    “…In contrast, the mortality risk was heavily influenced by CD conditioned by sex and age, accounting for 72.3% of total deaths (p = 0.001–0.008). Significant mortality risk (48%) was comprised of women and men (w, m) aged ≥56 years with diabetes (19% w and 27.9% m, cp < 0.0004), hypertension (11.5% w, cp = 0.0001), and CKD (3.5% w and 5.3% m, cp = 0.0009). …”
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  2. 253922
    “…Steps per day significantly increased in both the SAM (mean[SE] 1542[267], 95%CI:1014–2069, p<0.001) and FAST+SAM groups (1307[280], 752–1861, p<0.001), but not in the FAST group (406[238], 63–876, p=0.09). There were no deaths or serious study-related AEs and all other minor AEs were similar between groups. …”
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  3. 253923
    “…The difference in mean prescribing between quartile 4 and quartile 1 was 15.8 days of therapy per 100 patient-days (95% confidence interval [CI] 9.6–22.0), representing 30% higher antimicrobial prescribing in the fourth quartile than the first quartile. Patient in-hospital deaths, length of stay, ICU transfer and hospital readmission did not differ by physician quartile. …”
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  4. 253924
    “…Random forest competing risk models were used to estimate absolute 5‐year risk of hip fracture and absolute 5‐year risk of competing mortality (excluding post–hip fracture deaths). Models were constructed for both outcomes simultaneously; minimal depth was used to rank and select variables for smaller models. …”
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  5. 253925
    “…BACKGROUND: Gun violence in the United States rose continuously from 2010 to 2022, spiking during the pandemic, and peaking in 2021 at 48,830 deaths (14.8 per 100,000). Previous reports investigated health and financial burden associated with gunshot wounds (GSWs) during 2004 to 2013; however estimates related specifically to head and neck (H&N) injuries have been lacking. …”
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  6. 253926
  7. 253927
  8. 253928
    “…The implementation of artemisinin (ART) combination therapies (ACTs) has greatly decreased deaths caused by Plasmodium falciparum malaria, but increasing ACT resistance in Southeast Asia and Africa could reverse this progress. …”
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  9. 253929
    “…Although stroke-related mortality has declined in recent decades, the absolute number of new strokes (incidence), stroke deaths, and survivors of stroke has increased. With the increasing need of neurorehabilitation and the decreasing number of professionals, innovations are needed to ensure adequate care. …”
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  10. 253930
    “…SIMPLE SUMMARY: Swainsonine-containing plants are a poisonous plant widely distributed in grasslands around the world, poisoning by it can cause livestock deaths and economic losses to herdsmen. We have developed a sustained-release injection for the prevention of poisoning by swainsonine-containing plants. …”
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  11. 253931
    “…SIMPLE SUMMARY: Liver cancer represents one of the most lethal forms of cancer, with hepatocellular carcinoma (HCC) accounting for the majority of its incidences and deaths. Currently, sorafenib is the first-in-line option for treating advanced and unresectable HCC. …”
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  12. 253932
    “…Over 11.5 (IQR 10.8–12.2) years, there were 3706 ischaemic strokes, 795 haemorrhagic strokes, 26,025 major bleeding events and 28,851 deaths. eGFR(Cys) was more strongly associated with ischaemic stroke than eGFR(Cr): an effect that was more pronounced in women (men – HR: 1.16, 95% CI: 1.12–1.19; female to male comparison – HR: 1.11, 95% CI: 1.05–1.16, per 10 mL/min/1.73 m(2) decline in eGFR(Cys)). …”
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  13. 253933
    “…OBJECTIVE: Cervical cancer represents the fourth leading cause of cancer among women and is associated with over 311,000 annual deaths worldwide. Timely diagnosis is crucial given the lengthy pre-cancerous phase, which is typified by cervical intraepithelial neoplastic lesions. …”
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  14. 253934
  15. 253935
    “…These included major adverse cardiovascular events, non-AIDS-defining malignancies, and non-accidental deaths. We used pooled logistic regression with inverse probability weighting to estimate the survival curves and cumulative risk of clinical events. …”
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  16. 253936
    “…INTRODUCTION: By the end of October 2022, COVID-19 had infected more than 629 million people, with more than 6,5 million deaths worldwide. During the pandemic, there have not been any specific antiviral drugs to effectively treat COVID-19, but non-specific drugs have been used and may improve the prognosis of high-risk patients with the disease. …”
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  17. 253937
    “…Finally, results of the toxicity assay showed that EAME is safe and no deaths or changes in mice behavior were observed even when doses as high as 5 g/kg DW were used. …”
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  18. 253938
    “…Pooled frequencies of key AE indicators are shown below: any AEs, 77.8% [95% confidence interval (CI): 67.9–87.6]; grade ⩾ 3 AEs, 29.3% (95% CI: 24.2–34.4); serious AEs, 34.9% (95% CI: 28.1–41.7); AE leading to discontinuation, 13.3% (95% CI: 9.3–17.4); treatment-related deaths, 0.98% (95% CI: 0.5–1.5). AEs with a frequency exceeding 15% are shown below: fatigue, 30.1% (95% CI: 23.8–36.3); diarrhea, 21.7% (95% CI: 17.8–25.6); pruritus 17.9% (95% CI: 14.4–21.3); decreased appetite, 17.7% (95% CI: 13.7–22.0); nausea, 15.6% (95% CI: 12.1–19.6). …”
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  19. 253939
    “…Postnatal prevalence of major CHD decreased significantly due to early TOPs and intrauterine deaths. The introduction of first trimester screening resulted in a higher termination rate in the first trimester but did not revert the overall decreasing trend of termination for CHDs in general.…”
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  20. 253940
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