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  1. 255081
    “…BACKGROUND: We previously demonstrated that an Italian family affected by a severe dilated cardiomyopathy (DCM) with history of sudden deaths at young age, carried a mutation in the Lmna gene encoding for a truncated variant of the Lamin A/C protein (LMNA), R321X. …”
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    Targeting unfolded protein response reverts ER stress and ER Ca(2+) homeostasis in cardiomyocytes expressing the pathogenic variant of Lamin A/C R321X
  2. 255082
    “…BACKGROUND: Lung cancer is the leading cause of cancer-related deaths worldwide, and despite recent advances in targeted therapies and immunotherapies, the clinical benefit remains limited. …”
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    NPM3 as a novel oncogenic factor and poor prognostic marker contributes to cell proliferation and migration in lung adenocarcinoma
  3. 255083
    “…The relationship between COVID-19 cases or deaths for COVID-19 and altitude as continuous variable was determined using Spearman correlation test. …”
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    A U-shaped protection of altitude against mortality and infection of COVID-19 in Peru: an ecological study
  4. 255084
    “…BACKGROUND: Colorectal cancer (CRC) is the second leading cause of cancer-related deaths globally. It is essential to identify new CRC-associated therapeutic targets and diagnostic biomarkers. …”
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    Circular RNA hsa_circ_0064559 affects tumor cell growth and progression of colorectal cancer
  5. 255085
    “…Dyslipidemia is the most common risk factor for cardiovascular disease, causing more than 4 million deaths each year worldwide. However, there is very little evidence concerning the prevalence and pattern of dyslipidemia among cardiac patients in Ethiopia. …”
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    Dyslipidemia and its associated factors among adult cardiac patients at Ambo university referral hospital, Oromia region, west Ethiopia
  6. 255086
    “…Over a median follow up of 11.4 years, we observed 750 incident HF events (635 HF hospitalizations and 115 HF deaths). Compared to the lowest AL quartile (Q1), the fully adjusted hazards of an incident HF event increased in a graded fashion: Q2 HR 1.49 95% CI 1.12–1.98; Q3 HR 2.47 95% CI 1.89–3.23; Q4 HR 4.28 95% CI 3.28–5.59. …”
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    Allostatic load and incident heart failure in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study
  7. 255087
    por Rios-Blancas, Maria Jesus, Pando-Robles, Victoria, Razo, Christian, Carcamo, Cesar P., Mendoza, Walter, Pacheco-Barrios, Kevin, Miranda, J. Jaime, Lansingh, Van Charles, Demie, Takele Gezahegn, Saha, Manika, Okonji, Osaretin Christabel, Yigit, Arzu, Cahuana-Hurtado, Lucero, Chacón-Uscamaita, Pamela R., Bernabe, Eduardo, Culquichicon, Carlos, Chirinos-Caceres, Jesus Lorenzo, Cárdenas, Rosario, Alcalde-Rabanal, Jacqueline Elizabeth, Barrera, Francisco J., Quintanilla, Beatriz Paulina Ayala, Shorofi, Seyed Afshin, Wickramasinghe, Nuwan Darshana, Ferreira, Nuno, Almidani, Louay, Gupta, Vivek Kumar, Karimi, Hanie, Alayu, Daniel Shewaye, Benziger, Catherine P., Fukumoto, Takeshi, Mostafavi, Ebrahim, Redwan, Elrashdy Moustafa Mohamed, Gebrehiwot, Mesfin, Khatab, Khaled, Koyanagi, Ai, Krapp, Fiorella, Lee, Seung, Noori, Maryam, Qattea, Ibrahim, Rosenthal, Victor Daniel, Sakshaug, Joseph W., Wagaye, Birhanu, Zare, Iman, Ortega-Altamirano, Doris V., Murillo-Zamora, Efrén, Vervoort, Dominique, Silva, Diego Augusto Santos, Oulhaj, Abderrahim, Herrera-Serna, Brenda Yuliana, Mehra, Rahul, Amir-Behghadami, Mehrdad, Adib, Nasrin, Cortés, Sandra, Dang, Anh Kim, Nguyen, Binh Thanh, Mokdad, Ali H., Hay, Simon I., Murray, Christopher J. L., Lozano, Rafael, García, Patricia J.
    Publicado 2023
    “…The new design should aim to reduce premature deaths and maintain healthy longevity, focusing on effective coverage and treatment of NCDs and reducing and managing the related disability.…”
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    Estimating mortality and disability in Peru before the COVID-19 pandemic: a systematic analysis from the Global Burden of the Disease Study 2019
  8. 255088
    “…BACKGROUND: Cancer is still the most challenging disease and is responsible for many deaths worldwide. Considerable research now focuses on targeted therapy in cancer using natural components to improve anti-tumor efficacy and reduce unfavorable effects. …”
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    The effect of bovine milk lactoferrin-loaded exosomes (exoLF) on human MDA-MB-231 breast cancer cell line
  9. 255089
    “…BACKGROUND: Globally, one in three adults has hypertension, a condition that causes 51% of all deaths from stroke. Stroke is becoming a major public health problem and the most common cause of morbidity and mortality among non-communicable diseases in the world and Ethiopia. …”
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    Incidence of stroke and its predictors among hypertensive patients in Felege Hiwot comprehensive specialized hospital, Bahir Dar, Ethiopia, a retrospective follow-up study
  10. 255090
    “…Evidence exists that a large number of child deaths occur in India due to maternal and child malnutrition-related complications. …”
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    Contribution of low birth weight to childhood undernutrition in India: evidence from the national family health survey 2019–2021
  11. 255091
    “…The study had an average observation period of 1,218 days and recorded 89 deaths. After adjusting for age, sex, skeletal muscle mass index, cardiovascular disease, cancer, education, and serum albumin levels, a lower risk of all-cause mortality was observed in the highest protein intake (Q4) group than in the lowest protein intake (Q1) group (hazard ratio: 0.44, 95% confidence interval: 0.22–0.90, p-value: 0.020). …”
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    Dietary protein intake and all-cause mortality: results from The Kawasaki Aging and Wellbeing Project
  12. 255092
    “…Analysis of the subset of individuals who died in Yemen also suggested an increased, but non-significant hazard of dying during the war/pandemic period: this association tended towards significance when allowing for varying degrees of out-migration from Yemen across the cohort. The number of deaths amongst respondents’ siblings and children under five in Yemen were too low to allow meaningful analysis. …”
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    Adult mortality patterns in Yemen before and during armed conflict: evidence from a web survey of the global diaspora
  13. 255093
    por Ma, Mac Zewei, Chen, Sylvia Xiaohua
    Publicado 2023
    “…By employing random-intercept multilevel models, the results demonstrated significant and negative effects of state-level collectivism, as measured by the U.S collectivism index, on COVID-19 cases per million, COVID-19 deaths per million, and composite COVID-19 severity index, after controlling for confounding factors, such as socioeconomic development, ecological threats, disease protective behaviors, cultural norms, and political influences. …”
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    Beyond the surface: accounting for confounders in understanding the link between collectivism and COVID-19 pandemic in the United States
  14. 255094
    “…BACKGROUND: Syria has been in continuous conflict since 2011, resulting in more than 874,000 deaths and 13.7 million internally displaced people (IDPs) and refugees. …”
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    Health aid displacement during a decade of conflict (2011–19) in Syria: an exploratory analysis
  15. 255095
    “…H. pylori infection is the most severe known risk factor for gastric cancer (GC), which is the second highest cause of cancer-related deaths globally. We conducted a systematic review and meta-analysis to assess the global prevalence of GC in H. pylori-infected individuals. …”
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    The global prevalence of gastric cancer in Helicobacter pylori-infected individuals: a systematic review and meta-analysis
  16. 255096
    “…BACKGROUND: The opioid epidemic in the United States has had devastating consequences, with many opioid-related deaths and a significant economic toll. Opioids have a significant role in postoperative pain management. …”
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    Opioid versus non-opioid postoperative pain management in otolaryngology
  17. 255097
    “…BACKGROUND: Worldwide, opioid use causes more than 100,000 overdose deaths annually. Naloxone has proven efficacy in reversing opioid overdoses and is approved as an emergency antidote to opioid overdose. …”
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    A study protocol for a European, mixed methods, prospective, cohort study of the effectiveness of naloxone administration by community members, in reversing opioid overdose: NalPORS
  18. 255098
    “…BACKGROUND: Non-small cell lung cancer (NSCLC) is the predominant histological subtype of lung cancer and is the leading cause of cancer-related deaths globally. Quality of life is an important consideration for patients and current treatments can adversely affect health-related quality of life (HRQoL). …”
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    Health State Utility Values in Early-Stage Non-small Cell Lung Cancer: A Systematic Literature Review
  19. 255099
    por Han, Changwoo, Jang, Hoyeon, Oh, Juhwan
    Publicado 2023
    “…The estimated mortality exceeded the number of deaths from COVID-19 infection. Excess mortality should be monitored to estimate the overall impact of the pandemic on a nation. …”
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    Excess mortality during the Coronavirus disease pandemic in Korea
  20. 255100
    “…Moreover, 59.8% of patients experienced cytokine release syndrome. The pooled rate of deaths attributable to BsAbs was estimated at 0.1%. …”
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    Safety and efficacy of T-cell-redirecting bispecific antibodies for patients with multiple myeloma: a systematic review and meta-analysis
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