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  1. 255421
    “…Breast and lung cancer are two of the most lethal forms of cancer, responsible for a disproportionately high number of deaths worldwide. Both doctors and cancer patients express alarm about the rising incidence of the disease globally. …”
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    Revolutionizing anti-cancer drug discovery against breast cancer and lung cancer by modification of natural genistein: an advanced computational and drug design approach
  2. 255422
    “…Tuberculosis disease (TB), caused by Mycobacterium tuberculosis, is a major global public health problem, resulting in more than 1 million deaths each year. Drug resistance (DR), including multi-drug (MDR-TB), is making TB control difficult and accounts for 16% of new and 48% of previously treated cases. …”
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    Mixed infections in genotypic drug-resistant Mycobacterium tuberculosis
  3. 255423
    “…One patient in the low-risk group experienced grade 4 oral mucositis, while no other severe complications or treatment-related deaths were observed. The median follow-up period was 22 months (range, 5 to 57 months). …”
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    “Sandwich” protocol based on modified SMILE regimen for children with newly extranodal NK/T cell lymphoma, nasal type: a single-arm, single-center clinical study
  4. 255424
    “…Nigeria has the second highest pneumococcal disease burden globally, with an estimated ~49 000 child deaths caused by pneumococcal infections each year. …”
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    Molecular characterization of Streptococcus pneumoniae causing disease among children in Nigeria during the introduction of PCV10 (GSK)
  5. 255425
    “…There were no adverse events, late exclusions, or deaths. CONCLUSIONS AND RELEVANCE: In this nonrandomized controlled trial of HCV treatment at the point of diagnosis, the NOW model of care reduced steps between HCV testing and treatment initiation and resulted in high levels of treatment initiation, completion, and cure. …”
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    Community-Based Point-of-Diagnosis Hepatitis C Treatment for Marginalized Populations: A Nonrandomized Controlled Trial
  6. 255426
    “…Background: Clostridioides difficile infection (CDI) is a serious healthcare-associated infection responsible for >12,000 US deaths annually. Overtesting can lead to antibiotic overuse and potential patient harm when patients are colonized with C. difficile, but not infected, yet treated. …”
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    Effects of a hard stop for C. difficile testing: Provider uptake and patient outcomes
  7. 255427
    Publicado 2023
    “…This workshop point out that, even we have large regulatory framework on clean air, air pollution in the European Union continues to be the top environmental threat to health, leading to approx 400,000 early deaths annually and high health costs. Over 20 of the 27 EU countries fail to keep air quality standards, which for key pollutants are already less strict than what the World Health Organization (WHO) recommends. …”
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    8.E. Workshop: Digital Public Health and Climate change: The European Framework made easy
  8. 255428
    Publicado 2023
    “…Non-communicable diseases (NCDs) contribute for 74% of all deaths globally. They are also major cause of morbidity and disability. …”
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    11.F. Workshop: Health examination surveys to support decision making and for monitoring risk factors
  9. 255429
    “…INTRODUCTION: Prostate cancer (PCa) presents a significant health challenge in men, with a substantial number of deaths attributed to metastatic castration resistant PCa (mCRPC). …”
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    Regulation of SPDEF expression by DNA methylation in advanced prostate cancer
  10. 255430
    “…The overall median post-LTx survival was 66 mo. Most deaths occurred in the first year (infection n = 2, primary liver graft dysfunction n = 3, unknown cause n = 1). …”
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    Liver transplant in patients with primary sclerosing cholangitis: A retrospective cohort from Northeastern Brazil
  11. 255431
    “…BACKGROUND: Vaccination is one of the most cost-effective public health interventions that prevents millions of deaths. Although immunization coverage is increasing globally, many children in low- and middle-income countries drop out of the vaccination continuum. …”
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    Vaccination dropout and wealth related inequality among children aged 12–35 months in remote and underserved settings of Ethiopia: a cross-sectional evaluation survey
  12. 255432
    “…The mortality rate was slightly below of the estimation for the state in the period studied, which we believe could be related to the small number of samples evaluated, the underreporting of cases and deaths among this population, and the inconsistency of secondary data available for this study. …”
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    Genomic characterization of SARS-CoV-2 from an indigenous reserve in Mato Grosso do Sul, Brazil
  13. 255433
    “…Given the absence of bleeding-related deaths in HYPOFIB patients, this study does not provide evidence for the empiric use of cryoprecipitate in the initial administration of a massive transfusion protocol. …”
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    Hypofibrinogenemia following injury in 186 children and adolescents: identification of the phenotype, current outcomes, and potential for intervention
  14. 255434
    “…IMPORTANCE: Shigella species cause bacillary dysentery, the second leading cause of diarrheal deaths worldwide. There is a pressing need to identify novel molecular drug targets. …”
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    VirB, a key transcriptional regulator of Shigella virulence, requires a CTP ligand for its regulatory activities
  15. 255435
    “…On the other hand, infections or deaths among partners or relatives were defined as covid-related stressors. …”
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    COVID-19 and Mental Health: Psychological Impact of the Pandemic on Women during Pregnancy and Puerperium
  16. 255436
    “…METHODS: We developed a discrete-event simulation model, parameterized with the data on medically-attended RSV infections among infants under one year of age from 2010 to 2019, including outpatient care, hospitalisations, and deaths. Intervention scenarios targeting twelve monthly birth cohorts and pregnant women, reflecting the 2021 census data for Ontario, Canada were evaluated over a follow-up time horizon of one year from birth. …”
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    Cost-effectiveness analysis of nirsevimab and maternal RSVpreF vaccine strategies for prevention of Respiratory Syncytial Virus disease among infants in Canada: a simulation study
  17. 255437
    “…All-cause mortality within 30 days was 0 in the ≥ 5 day group and 5 (1%) in the ≤ 4 day group (p=0.61). No deaths were COVID-19 related. Hypoxia was observed during treatment in 25 (37%) in the ≥ 5 day group and 131 (32%) in the ≤ 4 day group (p=0.41); no difference in outcomes was observed between patients who did and did not develop hypoxia. …”
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    448. Real World Evaluation of Clinical Outcomes for Short-Duration Remdesivir Therapy in Hospitalized Patients with Mild-Moderate COVID-19
  18. 255438
    “…Reliance on broad spectrum antibiotics has contributed to antibiotic resistant organisms and nearly 5 million deaths in 2019 [1]. The goal of this study was to improve antibiotic stewardship by using MRSA nasal swab screening to expedite parenteral vancomycin discontinuation. …”
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    2807. Using Less of Our Big Guns: Vancomycin De-Escalation Using Methicillin-Resistant Staphylococcus aureus Nasal Swab Screening Protocol
  19. 255439
    “…RESULTS: The 10 cases included 7 from clinical isolates, 2 from enhanced surveillance and 1 from CT. 8 were HO. 7 deaths were during the CA admission, but only 1 due to CA, and 1 occurred > 60 days after positive culture [Table 1]. …”
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    2485. Candida auris Hospital Cluster: Were Our Unwelcome Guests Driven Away by the COVID-19 Delta Surge?
  20. 255440
    “…BACKGROUND: Clostridioides difficile infection (CDI) poses an urgent threat in the United States with an estimated 223,900 cases of hospitalization and 12,800 estimated deaths in 2017. CDI manifestations range from diarrhea, pseudomembranous colitis, to fulminant colitis. …”
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    686. Management and Outcomes of Patients Referred to a Specialty Clinic for C. difficile Infection
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