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255681por Fasanya, Henrietta, Dopico, Pablo Joaquin, Yeager, Zachary J., Fan, Hugh, Siemann, Dietmar W.“…DISCUSSION/SIGNIFICANCE OF IMPACT: OS is the most common primary bone tumor and the third leading cause of pediatric cancer deaths. At diagnosis, 80% of patients will present with metastasis, however only 20% of these cases are clinically detectable. …”
Publicado 2019
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255682por van Griensven, Johan, van Henten, Saskia, Mengesha, Bewketu, Kassa, Mekibib, Adem, Emebet, Endris Seid, Mengistu, Abdellati, Saïd, Asefa, Wondimu, Simegn, Tesfa, Debasu, Degnachew, Bogale, Tadfe, Gedamu, Yonas, Van Den Bossche, Dorien, Adriaensen, Wim, Van der Auwera, Gert, Cnops, Lieselotte, Vogt, Florian, Diro, Ermias“…The median follow-up time was 12 months (IQR 9–12). No deaths were reported during the study period. Most (95.5%) were on antiretroviral treatment at enrolment, for a median of 52 months (IQR 27–79). …”
Publicado 2019
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255683por Powell, Daniel A, Shubitz, Lisa F, Hsu, Amy, Davis, Joie, Holland, Steven M, Berghout, Joanne, Lussier, Yves A, Frelinger, Jeffrey A, Galgiani, John N“…Dissemination occurs in 8% of reports with significant morbidity and occasional deaths. DCM was found in 3 generations: grandmother (skin), mother (skin), and son (bone). …”
Publicado 2019
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255684por Bardossy, Ana C, Gokhale, Runa H, Hartnett, Kathleen, Hatfield, Kelly M, Jackson, Kelly A, Felsen, Christina B, McDonald, Robert, Kracalik, Ian, Lucas, Todd, McGovern, Olivia L, Van Beneden, Chris, Vallabhaneni, Snigdha, Williams, Sabrina R, Mendoza, Michael, Bohm, Michele K, Brooks, John, Asher, Alice K, Magill, Shelley S, Fiore, Anthony, Blog, Debra, Dufort, Elizabeth, See, Isaac, Dumyati, Ghinwa“…BACKGROUND: The age-adjusted rate of drug overdose deaths in the United States tripled from 1999 to 2016. …”
Publicado 2019
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255685“…BACKGROUND: Clostridium difficile infection (CDI) results in approximately a half a million cases and 15,000 deaths annually in the United States. Relapse rates vary between 20 and 50% and account for frequent readmissions and morbidity. …”
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255686por Gurram, Pooja, Shweta, F N U, Castillo Almeida, Natalia E, Khalil, Sarwat, Cano Cevallos, Edison J, Mahmood, Maryam, Abu Saleh, Omar“…Of the 5 patients with acute Q fever that progressed to persistent infection, 3/5(60%) progressed despite being on doxycycline and hydroxychloroquine. 8/29 patients with persistent Q fever had serological resolution at last follow-up. 2/4(50%) deaths were attributable to Q fever. CONCLUSION: Minority of the patients tested met the case definition. 25% of patients with acute disease progressed to chronic Q fever out of which 60%(3/5) progressed despite prophylaxis. …”
Publicado 2019
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255687“…Pennsylvania (PA) has the third highest rate of drug overdose deaths in the country, with Allegheny and Philadelphia counties having the highest rates in the country. …”
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255688por Huntington, Jennifer A, Yu, Brian, Li, Linping, Jensen, Erin, Bruno, Christopher, Rhee, Elizabeth G“…Rates of treatment-related TEAEs were low across treatment arms and CrCL subgroups with no treatment-related deaths reported. CONCLUSION: Similar clinical cure and Day 28 ACM rates at the TOC visit were found across treatment groups for all CrCL subgroups, consistent with the overall primary and key secondary efficacy results for the ASPECT-NP study. …”
Publicado 2019
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255689por Marlow, Mariel, Zhang, John, Clemmons, Nakia S, Marin, Mona, Patel, Manisha, Patel, Manisha“…Sixty-four patients were hospitalized and there were no deaths. CONCLUSION: About one-third of cases reported during the recent US mumps resurgence were in children and adolescents. …”
Publicado 2019
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255690“…BACKGROUND: Occurrence of cardiovascular disease (CVD) in the setting of chronic kidney disease (CKD) can be described as a “cruel alliance”, with CVD responsible for about half of all deaths among CKD patients. Chronic kidney disease patients are more likely to die from CVD than progress to end stage kidney disease (ESKD). …”
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255691por Hoang, Cuong Quoc, Nguyen, Thao Thanh Thi, Ho, Nguyen Xuan, Nguyen, Hai Duc, Nguyen, An Binh, Nguyen, Tham Hong Thi, Phan, Hung Cong, Phan, Lan Trong“…The predominant serotype was CV-A6, identified in 57/87 (65.5%) of the specimens. No deaths were reported. Among 581 household contacts, 148 were laboratory confirmed: 12/581 were RT-PCR-positive, 142/545 had a ≥ 4-fold increase of neutralizing antibodies against EV-A71, CV-A6 or CV-A16; 4 cases experienced HFMD in the past 4 weeks. …”
Publicado 2019
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255692por Perez, Freddy, Llau, Anthony, Gutierrez, Gamaliel, Bezerra, Haroldo, Coelho, Giovanini, Ault, Steven, Barbiratto, Sulamita Brandao, de Resende, Marcelo Carballo, Cerezo, Lizbeth, Kleber, Giovanni Luz, Pacheco, Oscar, Perez, Octavio Lenin, Picos, Victor, Rojas, Diana P., Siqueira, Joao Bosco, Suarez, Marco Fidel, Harris, Eva, Castellanos, Luis Gerardo, Espinal, Carlos, Martin, Jose Luis San“…RESULTS: The expert group established that in 2017, there was a generalised decreased incidence, severity and number of deaths due to dengue in the Americas, accompanied by a reduction in reported cases of both Zika and chikungunya virus infections, with no change in distribution among age groups affected. …”
Publicado 2019
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255693por Dalgaard, Frederik, Pieper, Karen, Verheugt, Freek, Camm, A John, Fox, Keith AA, Kakkar, Ajay K, Pallisgaard, Jannik L, Rasmussen, Peter V, van Weert, Henk, Lindhardt, Tommi Bo, Torp-Pedersen, Christian, Gislason, Gunnar H, Ruwald, Martin H, Harskamp, Ralf E“…At 1-year follow-up, a total of 2094 (2.3%) strokes/SE, 2642 (2.9%) major bleedings and 10 915 (12.0%) deaths occurred. The GARFIELD-AF model was well calibrated with the predicted risk for stroke/SE and major bleeding. …”
Publicado 2019
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255694por Kwan, Hoi Yee, Maddocks, Matthew, Nolan, Claire M., Jones, Sarah E., Patel, Suhani, Barker, Ruth E., Kon, Samantha S.C., Polkey, Michael I., Cullinan, Paul, Man, William D.‐C.“…There were 313 (17.8%) deaths over a median (interquartile range) follow‐up duration 1089 (547–1704) days. …”
Publicado 2019
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255695por Woodd, Susannah L., Montoya, Ana, Barreix, Maria, Pi, Li, Calvert, Clara, Rehman, Andrea M., Chou, Doris, Campbell, Oona M. R.“…BACKGROUND: Infection is an important, preventable cause of maternal morbidity, and pregnancy-related sepsis accounts for 11% of maternal deaths. However, frequency of maternal infection is poorly described, and, to our knowledge, it remains the one major cause of maternal mortality without a systematic review of incidence. …”
Publicado 2019
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255696por Rajan, Shaffin S., Sawe, Hendry R., Iyullu, Asha J., Kaale, Dereck A., Olambo, Nancy A., Mfinanga, Juma A., Weber, Ellen J.“…Within 7 days, 23 (18.7%) patients died and one-third 8 (34.8%) of these died within 24 h. There were no ED deaths. About 65.1% of the patients had severe anemia but only 60 (48.8%) received blood transfusion in the ED. …”
Publicado 2019
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255697por Holmes, Laurens, Lim, Andrew, Comeaux, Camillia R., Dabney, Kirk W., Okundaye, Osatohamwen“…With cardiovascular disease as the leading cause of mortality in the US and blacks/African Americans being disproportionately affected by hypertension (HTN) which contributes substantially to these deaths, reflecting the excess mortality and survival disadvantage of this sub-population relative to whites, understanding the molecular events, including epigenomic and socio-epigenomic modulations, is relevant to narrowing the black-white mortality risk differences. …”
Publicado 2019
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255698“…BACKGROUND: Osteosarcoma (OS) is the most common malignant primary bone tumor occurring in children and young adults, which occupies the second important cause of tumor-associated deaths among children and young adults. Recent studies have demonstrated that many microRNAs (miRNAs) have abnormal expression in OS, and can function as prognostic factors of OS patients. …”
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255699por Neugebauer, Romain, Schroeder, Emily B., Reynolds, Kristi, Schmittdiel, Julie A., Loes, Linda, Dyer, Wendy, Desai, Jay R., Vazquez-Benitez, Gabriela, Ho, P. Michael, Anderson, Jeff P., Pimentel, Noel, O’Connor, Patrick J.“…RESULTS: The 127 600 participants (mean [SD] age, 59.4 [12.6] years; 68 588 men [53.8%]; mean [SD] body mass index, 32.3 [7.1]) had a median follow-up of 4 quarters (interquartile range, 3-9 quarters) and experienced 5464 deaths overall (4.3%), 1729 MIs (1.4%), 1301 CVAs (1.0%), and 3082 CHF hospitalizations (2.4%). …”
Publicado 2020
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255700por Kovac, Evan, Carlsson, Sigrid V., Lilja, Hans, Hugosson, Jonas, Kattan, Michael W., Holmberg, Erik, Stephenson, Andrew J.“…Only 15 prostate cancer–specific deaths occurred during 13 years of follow-up, and 9 (60.0%) were among men with a baseline PSA level of 2.00 ng/mL or higher. …”
Publicado 2020
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