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255821por Basharkhah, Alireza, Lackner, Herwig, Karastaneva, Anna, Bergovec, Marko, Spendel, Stephan, Castellani, Christoph, Sorantin, Erich, Benesch, Martin, Liegl-Atzwanger, Bernadette, Smolle-Jüttner, Freyja-Maria, Urban, Christian, Höllwarth, Michael, Singer, Georg, Till, Holger“…All patients underwent postoperative chemotherapy; irradiation was performed in four children. Two deaths occurred 18 months and 7.5 years after diagnosis, respectively. …”
Publicado 2021
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255822por Delele, Tadesse Guadu, Biks, Gashaw Andargie, Abebe, Solomon Mekonnen, Kebede, Zemene Tigabu“…A pretested and interviewer-administered structured questionnaire adapted from the literature was employed to record neonatal outcomes (illnesses and/or deaths) at birth, 24 hours, 7(th), 14(th) and 28(th) day from birth. …”
Publicado 2021
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255823“…BACKGROUND: Colorectal cancer is a leading cause of cancer-related deaths worldwide. The human gut microbiome has become an active area of research for understanding the initiation, progression, and treatment of colorectal cancer. …”
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255824“…Background E-cigarette use, or vaping, is known to be associated with potentially life-threatening lung injury, with the Centers for Disease Control and Prevention reporting 2,807 hospitalizations and 68 deaths in the United States due to e-cigarette or vaping-associated lung injury. …”
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255825“…The primary blame for the high rates of COVID‐19 infections and deaths has been assigned to formal LTSS care settings, specifically nursing homes. …”
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255826por Fenta, Setegn Muche, Biresaw, Hailegebrael Birhan, Fentaw, Kenaw Derebe, Gebremichael, Shewayiref Geremew“…In sub-Saharan Africa, more than half of under-five deaths are preventable through immunization. Therefore, this study aimed to identify the determinant factors of full childhood immunization among children aged 12–23 months in sub-Saharan Africa. …”
Publicado 2021
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255827por Pignata, Sandro, Scambia, Giovanni, Villanucci, Alessandro, Naglieri, Emanuele, Ibarbia, Mikel Arruti, Brusa, Federica, Bourgeois, Hugues, Sorio, Roberto, Casado, Antonio, Reichert, Dietmar, Dopchie, Catherine, De Rivas, Beatriz, de Sande, Luis Miguel“…Most common grade 3/4 adverse events (AEs) were neutropenia (30.3%), anemia (6.4%), thrombocytopenia (5.5%), and asthenia (5.0%). No deaths attributed to treatment‐related AEs or unexpected AEs occurred. …”
Publicado 2021
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255828por Wang, Zi-Xian, Wu, Hao-Xiang, Xie, Li, Lin, Wu-Hao, Liang, Fei, Li, Jin, Yang, Zhi-Min, Xu, Rui-Hua“…Here we propose a novel surrogate endpoint, modified PFS (mPFS), which omits the events of disease progression (but not deaths) within 3 months after randomization. METHODS: PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials were searched for randomized trials studying ICIs in advanced solid tumors with available PFS and OS data up to May 2020. …”
Publicado 2021
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255829“…BACKGROUND: Cryptococcal meningitis in HIV-infected patients in sub-Saharan Africa accounts for three-quarters of the global cases and 135,000 deaths per annum. Current treatment includes the use of fluconazole and amphotericin B. …”
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255830por Christou, Niki, Meyer, Jeremy, Combescure, Christophe, Balaphas, Alexandre, Robert-Yap, Joan, Buchs, Nicolas C., Ris, Frédéric“…IMPORTANCE: Rectal cancers occupy the eighth position worldwide for new cases and deaths for both men and women. These cancers have a high tendency to form metastases in the mesorectum but also in the lateral lymph nodes. …”
Publicado 2021
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255831por Falchook, Gerald, Infante, Jeffrey, Arkenau, Hendrik-Tobias, Patel, Manish R., Dean, Emma, Borazanci, Erkut, Brenner, Andrew, Cook, Natalie, Lopez, Juanita, Pant, Shubham, Frankel, Arthur, Schmid, Peter, Moore, Kathleen, McCulloch, William, Grimmer, Katharine, O'Farrell, Marie, Kemble, George, Burris, Howard“…One fatal case of drug-related pneumonitis occurred with TVB-2640+paclitaxel; no other treatment-related deaths occurred. Target engagement (FASN inhibition) and inhibition of lipogenesis were demonstrated with TVB-2640. …”
Publicado 2021
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255832por Simoens, Steven, Bento-Abreu, Andre, Merckx, Barbara, Joubert, Sophie, Vermeersch, Steve, Pavelyev, Andrew, Varga, Stefan, Morais, Edith“…As a result, a GNV strategy would lead to reductions in HPV-related deaths. Both regional and national catch-up GNV strategies were projected to reduce cumulative HPV-related disease costs and were estimated to be cost-effective compared with FOV with incremental cost-effectiveness ratios of €8,062, €4,179, and €6,127 per quality-adjusted life-years in the three programs, respectively. …”
Publicado 2021
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255833“…BACKGROUND: Noncommunicable diseases (NCDs) are associated with the burden of premature deaths and huge medical costs globally. There is an increasing number of studies combining a multiple health behavior change (MHBC) intervention paradigm with eHealth approaches to jointly promote weight-related health behaviors among people with NCD; yet, a comprehensive summary of these studies is lacking. …”
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255834por Dubov, Alex, Fraenkel, Liana, Goldstein, Zil, Arroyo, Hansel, McKellar, Derek, Shoptaw, Steve“…BACKGROUND: Transgender people are at a high risk of suicidal ideation, suicide attempts, and deaths. Among transgender individuals, 77% and 41% engage in suicidal ideation and suicide attempt in their lifetime, respectively, which exceeds the general population rates (9.2% and 2.7%, respectively). …”
Publicado 2021
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255835por Rindal, D Brad, Asche, Stephen E, Gryczynski, Jan, Kane, Sheryl M, Truitt, Anjali R, Shea, Tracy L, Ziegenfuss, Jeanette Y, Schwartz, Robert P, Worley, Donald C, Mitchell, Shannon G“…BACKGROUND: Overdose deaths from prescription opioid analgesics are a continuing crisis in the United States. …”
Publicado 2021
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255836por Bobik, T. V., Kostin, N. N., Skryabin, G. A., Tsabai, P. N., Simonova, M. A., Knorre, V. D., Stratienko, O. N., Aleshenko, N. L., Vorobiev, I. I., Khurs, E. N., Mokrushina, Yu. A., Smirnov, I. V., Alekhin, A. I., Nikitin, A. E., Gabibov, A. G.“…The coronavirus disease outbreak in 2019 (COVID-19) has now achieved the level of a global pandemic and affected more than 100 million people on all five continents and caused over 2 million deaths. Russia is, needless to say, among the countries affected by SARS-CoV-2, and its health authorities have mobilized significant efforts and resources to fight the disease. …”
Publicado 2021
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255837por Shi, Jian, Zhao, Lian, Duncan, Brittany, Su, Jie, Manzo, Jale, Liu, He, Zhu, Yuan-Shan“…Approximately 70% to 100% of PCa deaths have bone metastasis, which may be associated with a specific bone microenvironment. …”
Publicado 2021
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255838por García-Arriaza, Juan, Garaigorta, Urtzi, Pérez, Patricia, Lázaro-Frías, Adrián, Zamora, Carmen, Gastaminza, Pablo, del Fresno, Carlos, Casasnovas, José M., S. Sorzano, Carlos Óscar, Sancho, David, Esteban, Mariano“…IMPORTANCE The continuous dissemination of the novel emerging SARS-CoV-2 virus, with more than 78 million infected cases worldwide and higher than 1,700,000 deaths as of 23 December 2020, highlights the urgent need for the development of novel vaccines against COVID-19. …”
Publicado 2021
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255839por Kiplimo, Richard, Kosgei, Mathew, Mwangi, Ann, Onyango, Elizabeth, Ogero, Morris, Koske, Joseph“…Introduction: Tuberculosis (TB) disease continues to be responsible for a high global burden with an estimated 10 million people falling ill each year and an estimated 1.45 million deaths. Widely carried out analyses to utilize routine data coming from this disease, and well-established in literature, have paid attention to time-to-event with sputum smear results being considered only at baseline or even ignored. …”
Publicado 2021
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255840por Chen, Wei-Kang, Wu, Zhi-Gang, Xiao, Yun-Bei, Wang, Qin-Quan, Yu, Dong-Dong, Cai, Jian, Zhou, Chao-Feng“…RESULTS: A total of 424 patients were included in the analysis, the median follow-up time was 5 months (interquartile range (IQR): 2-12) and 391 deaths (92.2%) in all patients were recorded. Among them, 192 (45.3%), 153 (36.1%), 137 (32.3%) and 127 (30.0%) patients were diagnosed with lung, bone, liver and brain metastases, respectively, while only 12 (2.8%) patients had brain metastases. …”
Publicado 2021
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