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256061por Fossouo Tagne, Joel, Yakob, Reginald Amin, Dang, Thu Ha, Mcdonald, Rachael, Wickramasinghe, Nilmini“…BACKGROUND: Adverse drug reactions (ADRs) are unintended consequences of medication use and may result in hospitalizations or deaths. Timely reporting of ADRs to regulators is essential for drug monitoring, research, and maintaining patient safety, but it has not been standardized in Australia. …”
Publicado 2023
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256062“…The AEs ranged from the adverse reactions listed in the safety profile (eg, myalgia, fever, fatigue, injection site pain, myocarditis or pericarditis, and thrombosis) to unlisted reactions (eg, irregular menstruation, changes in appetite and sleep, leukemia, and deaths). Our results showed a notable difference in the topics for each vaccine brand. …”
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256063por Micozzi, Alessandra, Minotti, Clara, Capria, Saveria, Cartoni, Claudio, Trisolini, Silvia Maria, Assanto, Giovanni Manfredi, Barberi, Walter, Moleti, Maria Luisa, Santilli, Stefania, Martelli, Maurizio, Gentile, Giuseppe“…Empirical combinations including CAZAVI were successful in 98% of cases (43/44 vs 33/38 for colistin-based EAT, p = 0.01), without modifications in 82% (36/44 vs 20/28, p = 0.02). All deaths occurred in patients treated with colistin-based EAT (4/38 vs 0/56, p = 0.02). …”
Publicado 2023
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256064por Starshinova, Anna, Belyaeva, Ekaterina, Doktorova, Natalia, Korotkevich, Ilya, Kudlay, Dmitry“…AIM: Because of the COVID-19 pandemic, many support programs for tuberculosis (TB) patients have been discontinued and TB mass screening activities decreased worldwide, resulting in a decrease in new case detection and an increase in TB deaths (WHO, WHO global lists of high burden countries for TB, multidrug/rifampicin-resistant TB (MDR/RR-TB) and TB/HIV, 2021–2025, 2021). …”
Publicado 2023
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256065por Meltzer, Andrew C., Wargowsky, Richard S., Moran, Seamus, Jordan, Tristan, Toma, Ian, Jepson, Tisha, Shu, Shiyu, Ma, Yan, McCaffrey, Timothy A.“…Clinical outcomes were abstracted from the CT scan and medical records. mRNA biomarker levels were calculated independent of the clinical outcomes and their accuracy was assessed to predict infectious diagnoses, surgery and hospital admission. 89 patients were enrolled; 21 underwent surgery; 47 underwent hospital admission; and, no deaths were observed within 30 days. In identifying which cases were likely infectious, mRNA biomarkers’ AUC values were: ALPL, 0.83; DEFA1 0.51; IL8RB, 0.74; and ALPL + IL8RB, 0.79. …”
Publicado 2023
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256066por Kishore, Kamal, Jaswal, Vidushi, Pandey, Anuj Kumar, Verma, Madhur, Koushal, Vipin“…During the initial investigation, we found that cases per million (CPM) and deaths per million (DPM) followed the same trend. …”
Publicado 2023
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256067por Kackos, Christina M., Surman, Sherri L., Jones, Bart G., Sealy, Robert E., Jeevan, Trushar, Davitt, Christopher J. H., Pustylnikov, Sergei, Darling, Tamarand L., Boon, Adrianus C. M., Hurwitz, Julia L., Samsa, Marcelo M., Webby, Richard J.“…The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in December of 2019 and is responsible for millions of infections and deaths across the globe. Vaccination against SARS-CoV-2 has proven effective to contain the spread of the virus and reduce disease. …”
Publicado 2023
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256068por Ren, Yulan, Wang, Tingting, Cheng, Xi, Ke, Guihao, Huang, Yan, Yang, Huijuan, Huang, Xiao, Tian, Wenjuan, Wang, Huaying“…No treatment-related serious AEs or deaths occurred. CONCLUSIONS: To our knowledge, this is the first prospective study assessing the efficacy and safety of apatinib in patients with uterine malignancy. …”
Publicado 2023
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256069por Ashworth, Jordan, Mathie, Dayna, Scott, Fiona, Mahendran, Yuvaraj, Woolhouse, Mark, Stoevesandt, Oda, Mduluza, Takafira, Mutapi, Francisca“…BACKGROUND: SARS-CoV-2 infections and deaths have been lower in Africa than in other continents, which could be attributed to previous exposure to other pathogens that induce protective cross-immunity or modify the immune phenotype. …”
Publicado 2023
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256070por Sun, Qiufen, Sun, Dong, Yu, Canqing, Guo, Yu, Sun, Dianjianyi, Pei, Pei, Yang, Ling, Chen, Yiping, Du, Huaidong, Schmidt, Dan, Stevens, Rebecca, Kang, Kai, Chen, Junshi, Chen, Zhengming, Li, Liming, Lv, Jun“…During a median follow-up of approximately 12.1 years, 12,725, 7,531, and 18,878 deaths were recorded in the respective analysis. Compared with clean fuel users who reported cooking with ventilation, participants who used solid fuels with ventilation and without ventilation had a difference in LE (95% confidence interval [CI]) at age 30 of −1.72 (−2.88, −0.57) and −2.62 (−4.16, −1.05) years for men and −1.33 (−1.85, −0.81) and −1.35 (−2.02, −0.67) years for women, respectively. …”
Publicado 2023
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256071“…RESULTS: To date, only 3 deaths have occurred in subjects treated with Ta1 (Group A), compared to 7 in the control (Group B). …”
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256072“…From 22(nd) December 2021, global vaccine doses were reduced substantially, which followed a dramatic reduction in cases and thereafter deaths with around one month's lag between each. As strong dependency on seasonality is noticed in certain countries and observing that regulation of vaccine doses has roles in modulating the transmission with certain lags, globally as well as regionally, our results have policy implications for the management of COVID. …”
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256073por Yin, Jason Dean-Chen“…The following five major categories of studies arose: antivaccination themes centered on the distrust of institutions, civil liberties, misinformation, conspiracy theories, and vaccine-specific concerns; provaccination themes centered on ensuring vaccine safety using scientific literature; framing being important and health professionals and personal stories having the largest impact on shaping vaccine opinion; the coverage of vaccination-related data mostly identifying negative vaccine content and revealing deeply fractured vaccine communities and echo chambers; and the public reacting to and focusing on certain signals—in particular cases, deaths, and scandals—which suggests a more volatile period for the spread of information. …”
Publicado 2022
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256074por Renaud, Emmanuelle, Ricordel, Charles, Corre, Romain, Leveiller, Guillaume, Gadby, Florence, Babey, Hélène, Annic, Josselin, Lucia, François, Bourbonne, Vincent, Robinet, Gilles, Descourt, Renaud, Orione, Charles, Quéré, Gilles, Geier, Margaux“…Two treatment-related deaths were reported. CONCLUSIONS: First-line pembrolizumab plus chemotherapy confirmed real-life efficacy for patients with advanced non-squamous non-small cell lung cancer. …”
Publicado 2023
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256075por Aulakh, A, Parker, B, Sullivan, B, Recsky, M, Oliveira, C, Richardson, W, Hirschkorn, P, Perini, R, Bak, A“…BACKGROUND: Colorectal cancer (CRC) is Canada's third most common cancer type and represents approximately 11% of all cancer deaths. While sedated colonoscopy or flexible sigmoidoscopy (FS) continues to be considered for CRC screening, these modalities have limitations and risks. …”
Publicado 2023
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256076“…BACKGROUND: Colorectal cancer (CRC) is the second most common cause of cancer related deaths in Canada. Approximately 1 in 13 males and 1 in 18 females will develop colorectal cancer in their lifetimes. …”
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256077por Lioznov, Dmitry, Amosova, Irina, Sheetikov, Savely A., Zornikova, Ksenia V., Serdyuk, Yana, Efimov, Grigory A., Tsyferov, Mikhail, Khmelevskii, Mikhail, Afanasiev, Andrei, Khomyakova, Nadezhda, Zubkov, Dmitry, Tikhonov, Anton, Zhu, Tao, Barreto, Luis, Dzutseva, Vitalina“…Of the six serious adverse events reported, none of the events were vaccine related. There were no deaths or premature withdrawals. CONCLUSION: A single-dose of Ad5-nCoV vaccine induced a marked specific humoral and cellular immune response with a favourable safety profile. …”
Publicado 2023
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256078por Ali, Shohaib, Mactier, Helen, Morelli, Alessandra, Hurd, Madeleine, Placzek, Anna, Knight, Marian, Ladhani, Shamez N., Draper, Elizabeth S., Sharkey, Don, Doherty, Cora, Kurinczuk, Jennifer J., Quigley, Maria A., Gale, Chris“…A total of 105 (95%) babies were discharged home; none of the three deaths before discharge was attributed to SARS-CoV-2. …”
Publicado 2023
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256079por Chillo, Pilly, Mutagaywa, Reuben, Nkya, Deogratias, Njelekela, Marina, Kwesigabo, Gideon, Kahabuka, Febronia, Kerry, Vanessa, Kamuhabwa, Appolinary“…BACKGROUND: Rheumatic Heart Disease (RHD) continues to cause suffering and premature deaths in many sub-Saharan Africa (SSA) countries, where the disease is still endemic. …”
Publicado 2023
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256080por Anderson, Benjamin M, Qasim, Muhammad, Correa, Gonzalo, Evison, Felicity, Gallier, Suzy, Ferro, Charles J, Jackson, Thomas A, Sharif, Adnan“…RESULTS: 453 participants were followed-up for a median of 685 days (IQR 544–812), during which there were 96 (21.2%) deaths and 1136 hospitalisations shared between 327 (72.1%) participants. …”
Publicado 2023
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