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256501por Jessup, Dana L, Glover IV, McKinley, Daye, Dania, Banzi, Lynda, Jones, Philip, Choy, Garry, Shepard, Jo-Anne O, Flores, Efrén J“…BACKGROUND: Lung cancer is the leading cause of cancer-related deaths in the United States. Despite mandated insurance coverage for eligible patients, lung cancer screening rates remain low. …”
Publicado 2018
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256502por Arnaldo, Paulo, Rovira-Vallbona, Eduard, Langa, Jerónimo S., Salvador, Crizolgo, Guetens, Pieter, Chiheb, Driss, Xavier, Bernardete, Kestens, Luc, Enosse, Sónia M., Rosanas-Urgell, Anna“…BACKGROUND: Malaria in pregnancy leads to serious adverse effects on the mother and the child and accounts for 75,000–200,000 infant deaths every year. Currently, the World Health Organization recommends intermittent preventive treatment of malaria in pregnancy (IPTp) with sulfadoxine–pyrimethamine (SP) at each scheduled antenatal care (ANC) visit. …”
Publicado 2018
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256503por Crabb, Simon, Danson, Sarah J., Catto, James W. F., McDowell, Cathy, Lowder, James N., Caddy, Joshua, Dunkley, Denise, Rajaram, Jessica, Ellis, Deborah, Hill, Stephanie, Hathorn, David, Whitehead, Amy, Kalevras, Mihalis, Huddart, Robert, Griffiths, Gareth“…BACKGROUND: Urothelial bladder cancer (UBC) accounts for 10,000 new diagnoses and 5000 deaths annually in the UK (Cancer Research UK, http://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/bladder-cancer, Cancer Research UK, Accessed 26 Mar 2018). …”
Publicado 2018
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256504por Fullerton, Terence, Binneman, Brendon, David, William, Delnomdedieu, Marielle, Kupiec, James, Lockwood, Peter, Mancuso, Jessica, Miceli, Jeffrey, Bell, Joanne“…In total, 46.2% of SAM-760 subjects reported adverse events (AE) versus 44.7% for placebo, and there were 5 (5.5%) serious AEs in the SAM-760 group versus 3 (3.2%) for placebo. There were two deaths, one prior to randomization and one in the SAM-760 group (due to a traffic accident during washout of active treatment). …”
Publicado 2018
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256505por Pin, Fabrizio, Barreto, Rafael, Kitase, Yukiko, Mitra, Sumegha, Erne, Carlie E., Novinger, Leah J., Zimmers, Teresa A., Couch, Marion E., Bonewald, Lynda F., Bonetto, Andrea“…Despite being responsible for one third of all cancer deaths, cachexia is generally under‐studied in OC due to a limited number of pre‐clinical animal models. …”
Publicado 2018
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256506por Carron, Maud, Chang, Yu-Mei, Momanyi, Kelvin, Akoko, James, Kiiru, John, Bettridge, Judy, Chaloner, Gemma, Rushton, Jonathan, O’Brien, Sarah, Williams, Nicola, Fèvre, Eric M., Häsler, Barbara“…In sub-Saharan Africa, 3.8 million deaths of children under-5 years of age are reported annually. …”
Publicado 2018
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256507por Abubakar, Mustapha, Sung, Hyuna, BCR, Devi, Guida, Jennifer, Tang, Tieng Swee, Pfeiffer, Ruth M., Yang, Xiaohong R.“…METHODS: In this population-based case series, we evaluated breast cancer risk factors in relation to 10-year all-cause mortality (ACM) and 5-year recurrence by molecular subtype among 3012 women with invasive breast cancer in Sarawak, Malaysia. A total of 579 deaths and 314 recurrence events occurred during a median follow-up period of ~ 24 months. …”
Publicado 2018
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256508por Burgess, Gary, Boyce, Malcolm, Jones, Margaret, Larsson, Lars, Main, Mark J., Morgan, Frazer, Phillips, Peter, Scrimgeour, Alison, Strimenopoulou, Foteini, Vajjah, Pavan, Zamacona, Miren, Palframan, Roger“…All TEAEs were mild or moderate; there were no deaths, serious adverse events, or clinically significant changes in vital signs, electrocardiograms, or laboratory parameters. …”
Publicado 2018
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256509por Patel, Achal P., Jagai, Jyotsna S., Messer, Lynne C., Gray, Christine L., Rappazzo, Kristen M., Deflorio-Barker, Stephanie A., Lobdell, Danelle T.“…Centers for Disease Control and Prevention to the EQI (n = 22,702,529; 144,741 deaths). We utilized multi-level regression to estimate associations between quartiles of county-level EQI and IM. …”
Publicado 2018
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256510por Malard, Florent, Labopin, Myriam, Cho, Christina, Blaise, Didier, Papadopoulos, Esperanza B., Passweg, Jakob, O’Reilly, Richard, Forcade, Edouard, Maloy, Molly, Volin, Liisa, Castro-Malaspina, Hugo, Hicheri, Yosr, Jakubowski, Ann A., Orvain, Corentin, Giralt, Sergio, Mohty, Mohamad, Nagler, Arnon, Perales, Miguel-Angel“…There were no statistical differences between ATG and CD34+ in terms of relapse [HR 1.52 (95% CI 0.96–2.42), p = 0.07], non-relapse mortality [HR 0.96 (95% CI 0.54–1.74), p = 0.90], overall survival [HR 1.43 (95% CI 0.97–2.11), p = 0.07], and leukemia-free survival [HR 1.25 (95% CI 0.88–1.78), p = 0.21]. Significantly, more deaths related to infection occurred in the CD34+ group (16/52 vs. 19/112, p = 0.04). …”
Publicado 2018
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256511“…BACKGROUND: Abortion-related mortality accounts for 8% of all global maternal deaths and 97% of the estimated 25 million unsafe abortions performed each year occur in low- and middle-income countries. …”
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256512por Mattison, Claire P, Groom, Holly, Donald, Judy, Salas, S Bianca, Marsh, Zachary, Burke, Rachel M, Schmidt, Mark A, Hall, Aron J, Naleway, Allison L“…The number of encounters per episode was lowest in those <5 years old (median: 1.0, mean: 1.5) and highest in those ≥65 (median: 2.0, mean: 2.5). Most deaths within 30 days from the start of an episode (131/161) were in those ≥65; there were none in those <5, 1 in those 5–17, 5 in those 18–44, and 24 in those 45–64. …”
Publicado 2018
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256513“…Compared to brand-name statins, the observed probability of occurrence of a CVE; HR: 1.31 [1.15–1.50], p < 0.001, and also all-cause deaths; HR: 1.36 [1.15–1.62], was significantly higher with generics; p < 0.001 in both cases. …”
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256514por Das, Jai K, Hadi, Yousaf Bashir, Salam, Rehana A, Hoda, Mehar, Lassi, Zohra S, Bhutta, Zulfiqar A“…BACKGROUND: Diarrhoeal disease accounts for millions of child deaths every year. Although the role of flies as vectors of infectious diarrhoea has been established, fly control is not often mentioned as an approach to decrease childhood diarrhoea. …”
Publicado 2018
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256515por Halliday, Brian P, Wassall, Rebecca, Lota, Amrit S, Khalique, Zohya, Gregson, John, Newsome, Simon, Jackson, Robert, Rahneva, Tsveta, Wage, Rick, Smith, Gillian, Venneri, Lucia, Tayal, Upasana, Auger, Dominique, Midwinter, William, Whiffin, Nicola, Rajani, Ronak, Dungu, Jason N, Pantazis, Antonis, Cook, Stuart A, Ware, James S, Baksi, A John, Pennell, Dudley J, Rosen, Stuart D, Cowie, Martin R, Cleland, John G F, Prasad, Sanjay K“…During the following 6 months, nine patients met the primary endpoint of relapse (Kaplan-Meier estimate of event rate 36·0% [95% CI 20·6–57·8]). No deaths were reported in either group and three serious adverse events were reported in the treatment withdrawal group: hospital admissions for non-cardiac chest pain, sepsis, and an elective procedure. …”
Publicado 2019
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256516por Ayano, Masahiro, Tsukamoto, Hiroshi, Mitoma, Hiroki, Kimoto, Yasutaka, Akahoshi, Mitsuteru, Arinobu, Yojiro, Miyamoto, Toshihiro, Horiuchi, Takahiko, Niiro, Hiroaki, Nagafuji, Koji, Harada, Mine, Akashi, Koichi“…No treatment-related deaths occurred in either treatment group. PFS of the CD34-selected group was greater than that of the unmanipulated group, and the 5-year PFS rates of the CD34-selected and unmanipulated group were 81.8% and 50% respectively. …”
Publicado 2019
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256517“…BACKGROUND: Over half a million children die each year of diarrheal illness, although nearly all deaths could be prevented with oral rehydration salts (ORS). …”
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256518por Mathew, Shilu, Smatti, Maria K., Al Ansari, Khalid, Nasrallah, Gheyath K., Al Thani, Asmaa A., Yassine, Hadi M.“…It accounts for approximately 1.34 million deaths annually in children younger than five years. …”
Publicado 2019
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256519por Friedrich, Alex W.“…In a recent publication, 426,277 healthcare-associated infections caused by antimicrobial resistant microorganisms were calculated to occur in the EU every year. Attributable deaths in the EU due to antimicrobial resistant microorganisms were estimated to be 33,110 per year. …”
Publicado 2019
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256520por Fagbamigbe, Adeniyi Francis“…Without an accurate, efficient and reliable diagnosis of malaria, the goal of eliminating malaria and reduction of malaria-related deaths to zero by 2020 will only remain elusive. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12936-019-2678-1) contains supplementary material, which is available to authorized users.…”
Publicado 2019
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