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256761por Melaku, Yohannes Adama, Wassie, Molla Mesele, Gill, Tiffany K., Zhou, Shao Jia, Tessema, Gizachew Assefa, Amare, Azmeraw T., Lakew, Yihunie, Hiruye, Abiy, Bekele, Tesfaye Hailu, Worku, Amare, Seid, Oumer, Endris, Kedir, Lemma, Ferew, Tesfay, Fisaha Haile, Yirsaw, Biruck Desalegn, Deribe, Kebede, Adams, Robert, Shi, Zumin, Misganaw, Awoke, Deribew, Amare“…RESULTS: In 2015, there were 58,783 [95% uncertainty interval (UI): 43,653–76,020] or 8.9% [95% UI: 6.1–12.5] estimated all-cause deaths attributable to CMU, 66,269 [95% UI: 39,367–106,512] or 9.7% [95% UI: 7.4–12.3] to dietary risks, 105,057 [95% UI: 66,167–157,071] or 15.4% [95% UI: 12.8–17.6] to metabolic risks and 5808 [95% UI: 3449–9359] or 0.9% [95% UI: 0.6–1.1] to low physical activity in Ethiopia. …”
Publicado 2018
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256762por Saha, Samir K, Schrag, Stephanie J, El Arifeen, Shams, Mullany, Luke C, Shahidul Islam, Mohammad, Shang, Nong, Qazi, Shamim A, Zaidi, Anita K M, Bhutta, Zulfiqar A, Bose, Anuradha, Panigrahi, Pinaki, Soofi, Sajid B, Connor, Nicholas E, Mitra, Dipak K, Isaac, Rita, Winchell, Jonas M, Arvay, Melissa L, Islam, Maksuda, Shafiq, Yasir, Nisar, Imran, Baloch, Benazir, Kabir, Furqan, Ali, Murtaza, Diaz, Maureen H, Satpathy, Radhanath, Nanda, Pritish, Padhi, Bijaya K, Parida, Sailajanandan, Hotwani, Aneeta, Hasanuzzaman, M, Ahmed, Sheraz, Belal Hossain, Mohammad, Ariff, Shabina, Ahmed, Imran, Ibne Moin, Syed Mamun, Mahmud, Arif, Waller, Jessica L, Rafiqullah, Iftekhar, Quaiyum, Mohammad A, Begum, Nazma, Balaji, Veeraraghavan, Halen, Jasmin, Nawshad Uddin Ahmed, A S M, Weber, Martin W, Hamer, Davidson H, Hibberd, Patricia L, Sadeq-ur Rahman, Qazi, Mogan, Venkat Raghava, Hossain, Tanvir, McGee, Lesley, Anandan, Shalini, Liu, Anran, Panigrahi, Kalpana, Abraham, Asha Mary, Baqui, Abdullah H“…BACKGROUND: More than 500 000 neonatal deaths per year result from possible serious bacterial infections (pSBIs), but the causes are largely unknown. …”
Publicado 2018
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256763por Sarwar, Martuza, Syed Khaja, Azharuddin Sajid, Aleskandarany, Mohammed, Karlsson, Richard, Althobiti, Maryam, Ødum, Niels, Mongan, Nigel P., Dizeyi, Nisthman, Johnson, Heather, Green, Andrew R., Ellis, Ian O., Rakha, Emad A., Persson, Jenny L“…Despite recent improvement in adjuvant therapies, triple-negative, and ER(+) subtypes of breast cancer (BC) with metastatic potentials remain the leading cause of BC-related deaths. We investigated the role of phosphatidylinositol-4-phosphate 5-kinase alpha (PIP5Kα), a key upstream factor of PI3K/AKT, and the therapeutic effect of PIP5Kα inhibitor on subtypes of BC. …”
Publicado 2018
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256764por Foeldvari, Ivan, Constantin, Tamàs, Vojinović, Jelena, Horneff, Gerd, Chasnyk, Vyacheslav, Dehoorne, Joke, Panaviene, Violeta, Sušić, Gordana, Stanevicha, Valda, Kobusinska, Katarzyna, Zuber, Zbigniew, Dobrzyniecka, Bogna, Nikishina, Irina, Bader-Meunier, Brigitte, Breda, Luciana, Doležalová, Pavla, Job-Deslandre, Chantal, Rumba-Rozenfelde, Ingrida, Wulffraat, Nico, Pedersen, Ronald D., Bukowski, Jack F., Vlahos, Bonnie, Martini, Alberto, Ruperto, Nicolino“…A single case of malignancy (Hodgkin’s lymphoma) and no cases of active tuberculosis, demyelinating disorders, or deaths were reported. CONCLUSIONS: Open-label etanercept treatment for up to 6 years was safe, well tolerated, and effective in patients with eoJIA, ERA, and PsA. …”
Publicado 2019
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256765por Huhn, Gregory D, Ramgopal, Moti, Crofoot, Gordon, Gathe, Joseph, Seyedkazemi, Sareh, Cosler, Patricia, Bruce Simonson, Richard, Luo, Donghan, Dunn, Keith“…One patient discontinued due to an adverse event (AE); incidences of grade 3/4 (10%) and serious (9%) AEs were low, with no serious AEs related to study drug and no deaths. CONCLUSION: In the first phase 3 study of an STR in a rapid initiation model, no patients rapidly starting D/C/F/TAF discontinued therapy due to lack of efficacy or had PDVF through 48 weeks. …”
Publicado 2019
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256766por Hoefer, Dina, Ruppert, Patricia S, Rausch-Phung, Elizabeth, Dufort, Elizabeth, Patel, Manisha, Patel, Manisha, Johns, Dylan, Gastanaduy, Paul, Gastanaduy, Paul, McDonald, Robert, Souto, Maria, Bryant, Patrick, McKay, Kevin T, McNulty, Lissette, McGraw, Nancy, Huang, Ada J, Wester, Rachel E, Ahmad, Nina, St. George, Kirsten, Sommer, Jamie N, Southwick, Karen L, Carrasco, Kimberly, Ostrowski, Stephanie, Adams, Eleanor, Adams, Eleanor, Levin, Toby R, Gelman, Irina, Hutton, Brad, Zucker, Howard, Blog, Debra“…Of the 371 cases, 263 (71%) were children who had received 0 doses of measles, mumps, rubella vaccine (MMR), 218 (83%) of whom were over 1 year of age (Table 1). There have been no deaths or documented cases of encephalitis. Twenty-eight (8%) patients were diagnosed with pneumonia and 25 (7%) patients were hospitalized. …”
Publicado 2019
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256767por Anderson, Jana J., Gray, Stuart R., Welsh, Paul, Mackay, Daniel F., Celis-Morales, Carlos A., Lyall, Donald M., Forbes, John, Sattar, Naveed, Gill, Jason M. R., Pell, Jill P.“…An association between artificially sweetened beverage intake and mortality did not persist after excluding deaths in the first 2 years of follow-up (landmark analysis) nor after excluding participants with recent weight loss. …”
Publicado 2020
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256768por Crim, Courtney, Gotfried, Mark, Spangenthal, Selwyn, Watkins, Michael, Emmett, Amanda, Crawford, Catriona, Baidoo, Charlotte, Castro-Santamaria, Ramiro“…AEs leading to discontinuation occurred in two subjects who received BAT/FF 300/100: post-treatment severe pneumonia (serious AE) and non-serious AEs of moderate vomiting and severe gastroenteritis; both were not considered drug-related. No deaths occurred. CONCLUSIONS: Six weeks of BAT/FF 300/100 treatment was non-inferior to placebo for change from baseline in HR, with no new clinically relevant general or cardiovascular safety signals. …”
Publicado 2020
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256769por Wu, Yanting, Zhang, Chen, Liu, Han, Duan, Chenchi, Li, Cheng, Fan, Jianxia, Li, Hong, Chen, Lei, Xu, Hualin, Li, Xiangjuan, Guo, Yi, Wang, Yeping, Li, Xiufeng, Li, Jing, Zhang, Ting, You, Yiping, Li, Hongmei, Yang, Shuangqi, Tao, Xiaoling, Xu, Yajuan, Lao, Haihong, Wen, Ming, Zhou, Yan, Wang, Junying, Chen, Yuhua, Meng, Diyun, Zhai, Jingli, Ye, Youchun, Zhong, Qinwen, Yang, Xiuping, Zhang, Dan, Zhang, Jing, Wu, Xifeng, Chen, Wei, Dennis, Cindy-Lee, Huang, He-feng“…The depressive rates were positively associated with the number of newly confirmed cases of coronavirus disease 2019 (P=.003), suspected infections (P=.004), and deaths per day (P=.001). Pregnant women who were underweight before pregnancy, primiparous, younger than 35 years, employed full time, in middle income category, and had appropriate living space were at increased risk for developing depressive and anxiety symptoms during the outbreak. …”
Publicado 2020
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256770por Leonardi, Craig, Reich, Kristian, Foley, Peter, Torii, Hideshi, Gerdes, Sascha, Guenther, Lyn, Gooderham, Melinda, Ferris, Laura K., Griffiths, Christopher E. M., ElMaraghy, Hany, Crane, Heidi, Patel, Himanshu, Burge, Russel, Gallo, Gaia, Shrom, David, Leung, Ann, Lin, Chen-Yen, Papp, Kim“…During the LTE period, exposure-adjusted incidence rates were 31.4 per 100 patient-years for treatment-emergent adverse events and 6.8 per 100 patient-years for serious adverse events. No deaths were reported. No new or unexpected safety findings were noted. …”
Publicado 2020
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256771por Alonge, Olakunle, Bishai, David, Wadhwaniya, Shirin, Agrawal, Priyanka, Rahman, Aminur, Dewan Hoque, Emdad Md., Baset, Kamran Ul, Salam, Shumona Sharmin, Bhuiyan, Al-Amin, Islam, Md Irteja, Talab, Abu, Rahman, Qazi Sadeq-ur, Rahman, Fazlur, El-Arifeen, Shams, Hyder, Adnan A.“…All children were followed-up until their 48-month birthday or administrative censoring (fixed timepoint to stop observing the drowning deaths), after a two-year implementation period (2014–2016). …”
Publicado 2020
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256772por Engelhard, Victor H, Obeng, Rebecca C, Cummings, Kara L, Petroni, Gina R, Ambakhutwala, Angela L, Chianese-Bullock, Kimberly A, Smith, Kelly T, Lulu, Amanda, Varhegyi, Nikole, Smolkin, Mark E, Myers, Paisley, Mahoney, Keira E, Shabanowitz, Jeffrey, Buettner, Nico, Hall, Emily H, Haden, Kathleen, Cobbold, Mark, Hunt, Donald F, Weiss, Geoffrey, Gaughan, Elizabeth, Slingluff, Jr, Craig L“…All had grade 1 or 2 treatment-related AEs, but there were no grade 3–4 AEs, DLTs or deaths on study. T-cell responses were induced to the pIRS2(1097-1105) peptide in 5/12 patients (42%, 90% CI 18% to 68%) and to the pBCAR3(126-134) peptide in 2/12 patients (17%, 90% CI 3% to 44%). …”
Publicado 2020
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256773por Komenda, Martin, Bulhart, Vojtěch, Karolyi, Matěj, Jarkovský, Jiří, Mužík, Jan, Májek, Ondřej, Šnajdrová, Lenka, Růžičková, Petra, Rážová, Jarmila, Prymula, Roman, Macková, Barbora, Březovský, Pavel, Marounek, Jan, Černý, Vladimír, Dušek, Ladislav“…The web portal’s primary objective is to publish a well-arranged visualization and clear explanation of basic information consisting of the overall numbers of performed tests, confirmed cases of COVID-19, COVID-19-related deaths, the daily and cumulative overviews of people with a positive COVID-19 case, performed tests, location and country of infection of people with a positive COVID-19 case, hospitalizations of patients with COVID-19, and distribution of personal protective equipment. …”
Publicado 2020
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256774por Lawrence, Christopher, Nieto, Jose, Parsons, Willis G., Roy, André, Guda, Nalini M., Steinberg, Stephen E., Hasan, Muhammad K., Bucobo, Juan Carlos, Nagula, Satish, Dey, Nicholas D., Buscaglia, Jonathan M.“…There were no cases of post-procedure stent migration, stent-related perforation, or stent-related deaths. CONCLUSIONS: This newly designed and marketed biliary SEMS system appears to be effective at relieving biliary obstruction and preventing re-intervention within 6 months of insertion in the overwhelming majority of patients. …”
Publicado 2020
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256775por Meessen, Jennifer M.T.A., Cardinale, Daniela, Ciceri, Fabio, Sandri, Maria Teresa, Civelli, Maurizio, Bottazzi, Barbara, Cucchi, GianFranco, Menatti, Elisabetta, Mangiavacchi, Maurizio, Condorelli, Gianluigi, Barbieri, Enrico, Gori, Stefania, Colombo, Alessandro, Curigliano, Giuseppe, Salvatici, Michela, Pastori, Paolo, Ghisoni, Francesco, Bianchi, Alessandra, Falci, Cristina, Cortesi, Pietro, Farolfi, Alberto, Monopoli, Anna, Milandri, Carlo, Bregni, Marco, Malossi, Alessandra, Nassiacos, Daniele, Verusio, Claudio, Staszewsky, Lidia, Leone, Roberto, Novelli, Deborah, Balconi, Giovanna, Nicolis, Enrico B., Franzosi, Maria Grazia, Masson, Serge, Garlanda, Cecilia, Mantovani, Alberto, Cipolla, Carlo M., Latini, Roberto“…During additional follow‐up 13 more deaths occurred, leading to a total of 23 (9.5%), all due to a non‐cardiovascular cause. …”
Publicado 2020
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256776por Guerra, Julio A., Zhang, Chengxian, Bard, Jonathan E., Yergeau, Donald, Halasa, Natasha, Gómez-Duarte, Oscar G.“…Although the STEC O157 serogroup accounts for the highest number of infections, HUS-related complications and deaths, the STEC non-O157, as a group, accounts for a larger proportion of STEC infections and lower HUS cases. …”
Publicado 2020
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256777por Entrenas Castillo, Marta, Entrenas Costa, Luis Manuel, Vaquero Barrios, José Manuel, Alcalá Díaz, Juan Francisco, López Miranda, José, Bouillon, Roger, Quesada Gomez, José Manuel“…Outcomes of effectiveness included rate of ICU admission and deaths. RESULTS: Of 50 patients treated with calcifediol, one required admission to the ICU (2%), while of 26 untreated patients, 13 required admission (50 %) p value X(2) Fischer test p < 0.001. …”
Publicado 2020
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256778“…Antenatal care utilization is a key intervention to reduce these deaths through problem detection and treatment, promotion of health seeking behavior, and preparing pregnant women for birth. …”
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256779por Shibre, Gebretsadik, Zegeye, Betregiorgis, Ahinkorah, Bright Opoku, Keetile, Mpho, Yaya, Sanni“…BACKGROUND: Majority of maternal deaths are avoidable through quality obstetric care such as Cesarean Section (CS). …”
Publicado 2020
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256780por De Giglio, Osvalda, Diella, Giusy, Lopuzzo, Marco, Triggiano, Francesco, Calia, Carla, Pousis, Chrysovalentinos, Fasano, Fabrizio, Caggiano, Giuseppina, Calabrese, Giuseppe, Rafaschieri, Vincenza, Carpagnano, Federica, Carlucci, Matilde, Gesualdo, Loreto, Ricci, Maria Luisa, Scaturro, Maria, Rota, Maria Cristina, Bonadonna, Lucia, Lucentini, Luca, Montagna, Maria Teresa“…The epidemic gradually started in Italy at the end of February 2020, and by May 31, 2020, 232,664 cases and 33,340 deaths were confirmed. As a result of this pandemic, the Italian Ministerial Decree issued on March 11, 2020, enforced lockdown; therefore, many social, recreational, and cultural centers remained closed for months. …”
Publicado 2020
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