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  1. 256861
    “…As of July 2, 2022, COVID-19 has caused more than 545 million infections and 6.3 million deaths worldwide, posing a significant threat to human health. …”
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    Effectiveness and safety analysis of SanHanHuaShi granules for the treatment of coronavirus disease 2019: Study protocol and statistical analysis plan for a randomized, parallel-controlled, open-label clinical trial
  2. 256862
    “…Sixty-seven (67) confirmed in 12 LGAs with 15 deaths [Case fatality rate (CFR 22.4%)]. Among confirmed cases, median age was 24.8, (range 64 (1-64) years; Fifty-one (76.1%) were males; and only 13 (19.4%) had a history of YF vaccination. …”
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    Epidemiological description of and response to a large yellow fever outbreak in Edo state Nigeria, September 2018 - January 2019
  3. 256863
    por Stepniewska, Kasia, Allen, Elizabeth N., Humphreys, Georgina S., Poirot, Eugenie, Craig, Elaine, Kennon, Kalynn, Yilma, Daniel, Bousema, Teun, Guerin, Philippe J., White, Nicholas J., Price, Ric N., Raman, Jaishree, Martensson, Andreas, Mwaiswelo, Richard O., Bancone, Germana, Bastiaens, Guido J. H., Bjorkman, Anders, Brown, Joelle M., D’Alessandro, Umberto, Dicko, Alassane A., El-Sayed, Badria, Elzaki, Salah-Eldin, Eziefula, Alice C., Gonçalves, Bronner P., Hamid, Muzamil Mahdi Abdel, Kaneko, Akira, Kariuki, Simon, Khan, Wasif, Kwambai, Titus K., Ley, Benedikt, Ngasala, Billy E., Nosten, Francois, Okebe, Joseph, Samuels, Aaron M., Smit, Menno R., Stone, Will J. R., Sutanto, Inge, Ter Kuile, Feiko, Tine, Roger C., Tiono, Alfred B., Drakeley, Chris J., Gosling, Roly, Stergachis, Andy, Barnes, Karen I., Chen, Ingrid
    Publicado 2022
    “…One blood transfusion was reported in the primaquine arms, and there were no primaquine-related deaths. In controlled studies, the proportions with either haematological or any serious adverse event were similar between primaquine and no primaquine arms. …”
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    Safety of single-dose primaquine as a Plasmodium falciparum gametocytocide: a systematic review and meta-analysis of individual patient data
  4. 256864
    “…Mozambique contributes 4% of the global malaria cases, and malaria is responsible for one-quarter of all deaths in the country. Based on recommendations in the Malaria Strategic Plan, the Malaria Consortium, in partnership with the National Malaria Control Programme in Mozambique, initiated a phased SMC implementation study in the northern province of Nampula. …”
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    Feasibility, Acceptability, and Protective Efficacy of Seasonal Malaria Chemoprevention Implementation in Nampula Province, Mozambique: Protocol for a Hybrid Effectiveness-Implementation Study
  5. 256865
    “…Recent estimate put the deaths associated with bacterial antimicrobial resistance in 2019 at 4.95 million worldwide. …”
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    Multi-drug resistant bacteria isolates from lymphatic filariasis patients in the Ahanta West District, Ghana
  6. 256866
    “…Though proper and timely referral prevents the majority of deaths from obstetric complications in developing countries, more than 50% of referrals are self-referral trends. …”
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    Self-referrals and associated factors among laboring mothers at Dilla University Referral Hospital, Dilla, Gedeo Zone, Ethiopia: a cross-sectional study
  7. 256867
    “…In Uganda, it accounts for 28.9% of all neonatal deaths. With a view to inform policy and practice interventions to reduce adverse neonatal outcomes, we aimed to determine the prevalence and factors associated with birth asphyxia at two referral hospitals in Northern Uganda. …”
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    Factors associated with birth asphyxia among term singleton births at two referral hospitals in Northern Uganda: a cross sectional study
  8. 256868
    “…Eight product recipients died 8–99 days after product implantation (three deaths were attributed to tuberculosis after recognition of the outbreak). …”
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    Nationwide tuberculosis outbreak in the USA linked to a bone graft product: an outbreak report
  9. 256869
    “…Hypoxic encephalopathy accounted for 92% of deaths. CONCLUSIONS: Protocol-guided management effectively optimizes outcomes in patients with maxillofacial bleeding.…”
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    Effectiveness of protocolized management for patients sustaining maxillofacial fracture with massive oronasal bleeding: a single-center experience
  10. 256870
    “…No treatment-related deaths occurred. Sixty percent of the patients who discontinued treatment eventually received one or more lines of subsequent therapy. …”
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    Real-World Activity and Safety of Trifluridine-Tipiracil Plus Bevacizumab Therapy in Patients with Refractory Metastatic Colorectal Cancer
  11. 256871
    “…RESULTS: 148 patients were screened from November 2019 to March 2021. 48 patients did not want to participate or were unable to participate in the follow-up. 100 patients were randomized and 85 patients were available for full analysis due to there being 4 deaths, 6 withdrawals, 1 wrong inclusion, 1 emigration, 1 refracture, 1 patient with compartment syndrome, and 1 who was advised to undergo surgery after being randomized to non-operative treatment. …”
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    VOLCON: a randomized controlled trial investigating complications and functional outcome of volar plating vs casting of unstable distal radius fractures in patients older than 65 years
  12. 256872
    “…RESULTS: After excluding those younger than 18 years and events with missing or invalid entries, 21,139 ICU admissions remained from 18,094 patients between 2001 and 2012, including 2,797 in-hospital deaths. Three models were produced: two Recurrent Neural Networks (RNNs) which differed significantly in internal weights and variables, and a Boosted Tree Classifier (BTC). …”
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    Inter operator variability of machine learning researchers predicting all-cause mortality in patients admitted to intensive care unit
  13. 256873
    “…Over time, numerous empirical studies have shown that majority of HBV-related yearly global deaths are secondary to carcinoma of the liver. It is also known that HBV infected Women have the potential to transmit the infection vertically to their infants during pregnancy. …”
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    Dynamics of Hepatitis B infection prevention practices among pregnant women attending antenatal care at Lubaga Hospital Kampala, Uganda using the constructs of information-motivation-behavioural skills model
  14. 256874
    “…No treatment-related deaths or serious TEAEs were observed. Notably, higher c-Kit levels were an independent factor for superior PFS (HR = 0.032; 95% CI, 0.002–0.606; P = 0.022). …”
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    A multi-center, single-arm, phase II study of anlotinib plus paclitaxel and cisplatin as the first-line therapy of recurrent/advanced esophageal squamous cell carcinoma
  15. 256875
    “…The use of insecticide-treated nets is one of the proven interventions for mitigating malaria and its associated deaths in endemic regions, including Ghana. Meanwhile, there is limited evidence on the extent of inequality in insecticide-treated nets use by pregnant women in Ghana. …”
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    Inequalities in the use of insecticide-treated nets by pregnant women in Ghana, 2011 and 2017
  16. 256876
    “…During a median follow-up of 7.3 years, patients were seen 12 times at the clinic, and we recorded 1325 MACE, 1593 HF-CVM, and 917 deaths. By the end of the study, each patient spent on average 63.6% of time in Group 1. …”
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    Management of type 2 diabetes with a treat-to-benefit approach improved long-term cardiovascular outcomes under routine care
  17. 256877
    “…Overall, there were no deaths during the hospital stay. Mortality after 12 months was 21.7% for the conservative, 8.4% for the interventional and 13.6% for the surgical therapy group; the differences are significant. …”
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    Comparative outcome of different treatment options for fragility fractures of the sacrum
  18. 256878
    “…In 2019 the global disease burden was estimated to be 754,000 DALYs and resulted in 2090 deaths. In the absence of a vaccination strategy, treatment of ascariasis has relied on anthelminthic chemotherapy, but drug resistance is a concern. …”
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    Transcriptome profiling of male and female Ascaris lumbricoides reproductive tissues
  19. 256879
    “…Median time to parasite clearance (Kaplan–Meier) was 56.1 h with ferroquine, more rapid with artefenomel, but similar for all doses (30.0 h). There were no deaths. Adverse events (AEs) of any cause occurred in 51.4% (18/35) of patients with ferroquine 400 mg alone, and 58.3% (21/36), 66.7% (24/36), and 72.7% (24/33) with 300, 600, and 1000 mg artefenomel, respectively. …”
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    Randomized, open-label, phase 2a study to evaluate the contribution of artefenomel to the clinical and parasiticidal activity of artefenomel plus ferroquine in African patients with uncomplicated Plasmodium falciparum malaria
  20. 256880
    “…Secondary outcomes presented in this paper included: all-cause hospitalisations, hospitalisations for diabetes/mental health problems/COPD, deaths, and emergency department visits. RESULTS: The trial was under-powered because the recruitment target was not met. …”
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    Impact of removing prescription co-payments on the use of costly health services: a pragmatic randomised controlled trial
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