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257121por Aryal, Krishna Kumar, Mehata, Suresh, Neupane, Sushhama, Vaidya, Abhinav, Dhimal, Meghnath, Dhakal, Purushottam, Rana, Sangeeta, Bhusal, Chop Lal, Lohani, Guna Raj, Paulin, Frank Herbert, Garg, Renu Madanlal, Guthold, Regina, Cowan, Melanie, Riley, Leanne Margaret, Karki, Khem Bahadur“…BACKGROUND: World Health Organization (WHO) estimates for deaths attributed to Non Communicable Diseases (NCDs) in Nepal have risen from 51% in 2010 to 60% in 2014. …”
Publicado 2015
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257122por Valecha, Neena, Savargaonkar, Deepali, Srivastava, Bina, Rao, B. H. Krishnamoorthy, Tripathi, Santanu K., Gogtay, Nithya, Kochar, Sanjay Kumar, Kumar, Nalli Babu Vijaya, Rajadhyaksha, Girish Chandra, Lakhani, Jitendra D., Solanki, Bhagirath B., Jalali, Rajinder K., Arora, Sudershan, Roy, Arjun, Saha, Nilanjan, Iyer, Sunil S., Sharma, Pradeep, Anvikar, Anupkumar R.“…The commonly reported clinical adverse events in the FDC of arterolane maleate and PQP versus chloroquine group were vomiting (5.0 vs 5.1 %), headache (1.3 vs 3.2 %) and prolonged QT (1.9 vs 3.2 %). No deaths were reported. The pharmacokinetic analysis indicates that arterolane maleate is well absorbed and has a relatively short t(1/2) of 3.2 h. …”
Publicado 2016
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257123por Dearnaley, David, Syndikus, Isabel, Mossop, Helen, Khoo, Vincent, Birtle, Alison, Bloomfield, David, Graham, John, Kirkbride, Peter, Logue, John, Malik, Zafar, Money-Kyrle, Julian, O'Sullivan, Joe M, Panades, Miguel, Parker, Chris, Patterson, Helen, Scrase, Christopher, Staffurth, John, Stockdale, Andrew, Tremlett, Jean, Bidmead, Margaret, Mayles, Helen, Naismith, Olivia, South, Chris, Gao, Annie, Cruickshank, Clare, Hassan, Shama, Pugh, Julia, Griffin, Clare, Hall, Emma“…No treatment-related deaths were reported. INTERPRETATION: Hypofractionated radiotherapy using 60 Gy in 20 fractions is non-inferior to conventional fractionation using 74 Gy in 37 fractions and is recommended as a new standard of care for external-beam radiotherapy of localised prostate cancer. …”
Publicado 2016
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257124por Do, Nga T T, Ta, Ngan T D, Tran, Ninh T H, Than, Hung M, Vu, Bich T N, Hoang, Long B, van Doorn, H Rogier, Vu, Dung T V, Cals, Jochen W L, Chandna, Arjun, Lubell, Yoel, Nadjm, Behzad, Thwaites, Guy, Wolbers, Marcel, Nguyen, Kinh V, Wertheim, Heiman F L“…Adverse events were rare, with no deaths and a total of 14 hospital admissions (six in the C-reactive protein group and eight in the control group). …”
Publicado 2016
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257125por Richards, David A, Ekers, David, McMillan, Dean, Taylor, Rod S, Byford, Sarah, Warren, Fiona C, Barrett, Barbara, Farrand, Paul A, Gilbody, Simon, Kuyken, Willem, O'Mahen, Heather, Watkins, Ed R, Wright, Kim A, Hollon, Steven D, Reed, Nigel, Rhodes, Shelley, Fletcher, Emily, Finning, Katie“…Two (1%) non-trial-related deaths (one [1%] multidrug toxicity in the BA group and one [1%] cancer in the CBT group) and 15 depression-related, but not treatment-related, serious adverse events (three in the BA group and 12 in the CBT group) occurred in three [2%] participants in the BA group (two [1%] patients who overdosed and one [1%] who self-harmed) and eight (4%) participants in the CBT group (seven [4%] who overdosed and one [1%] who self-harmed). …”
Publicado 2016
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257126por Tashkin, Donald P, Roth, Michael D, Clements, Philip J, Furst, Daniel E, Khanna, Dinesh, Kleerup, Eric C, Goldin, Jonathan, Arriola, Edgar, Volkmann, Elizabeth R, Kafaja, Suzanne, Silver, Richard, Steen, Virginia, Strange, Charlie, Wise, Robert, Wigley, Fredrick, Mayes, Maureen, Riley, David J, Hussain, Sabiha, Assassi, Shervin, Hsu, Vivien M, Patel, Bela, Phillips, Kristine, Martinez, Fernando, Golden, Jeffrey, Connolly, M Kari, Varga, John, Dematte, Jane, Hinchcliff, Monique, Fischer, Aryeh, Swigris, Jeffrey, Meehan, Richard, Theodore, Arthur, Simms, Robert, Volkov, Suncica, Schraufnagel, Dean E, Scholand, Mary Beth, Frech, Tracy, Molitor, Jerry A, Highland, Kristin, Read, Charles A, Fritzler, Marvin J, Kim, Grace Hyun J, Tseng, Chi-Hong, Elashoff, Robert M“…A greater number of patients on CYC than on MMF prematurely withdrew from study drug (32 vs 20) and failed treatment (2 vs 0), and the time to stopping treatment was significantly shorter in the CYC arm (p=0·019). Sixteen deaths occurred (11 CYC; 5 MMF) with most due to progressive ILD. …”
Publicado 2016
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257127por Abubakar, Mustapha, Orr, Nick, Daley, Frances, Coulson, Penny, Ali, H. Raza, Blows, Fiona, Benitez, Javier, Milne, Roger, Brenner, Herman, Stegmaier, Christa, Mannermaa, Arto, Chang-Claude, Jenny, Rudolph, Anja, Sinn, Peter, Couch, Fergus J., Devilee, Peter, Tollenaar, Rob A. E. M., Seynaeve, Caroline, Figueroa, Jonine, Sherman, Mark E., Lissowska, Jolanta, Hewitt, Stephen, Eccles, Diana, Hooning, Maartje J., Hollestelle, Antoinette, Martens, John W. M., van Deurzen, Carolien H. M., Investigators, kConFab, Bolla, Manjeet K., Wang, Qin, Jones, Michael, Schoemaker, Minouk, Wesseling, Jelle, van Leeuwen, Flora E., Van ‘t Veer, Laura, Easton, Douglas, Swerdlow, Anthony J., Dowsett, Mitch, Pharoah, Paul D., Schmidt, Marjanka K., Garcia-Closas, Montserrat“…METHODS: We utilised 143 tissue microarrays containing 15,313 tumour tissue cores from 8088 breast cancer patients in 10 collaborating studies. A total of 1401 deaths occurred during a median follow-up of 7.5 years. …”
Publicado 2016
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257128por Marjuki, Henju, Mishin, Vasiliy P., Chai, Ning, Tan, Man-Wah, Newton, Elizabeth M., Tegeris, John, Erlandson, Karl, Willis, Melissa, Jones, Joyce, Davis, Todd, Stevens, James, Gubareva, Larisa V.“…IMPORTANCE Zoonotic influenza viruses, such as A(H5N1) and A(H7N9) subtypes, have caused severe disease and deaths in humans, raising public health concerns. …”
Publicado 2016
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257129por García de Veas Silva, José Luis, Bermudo Guitarte, Carmen, Menéndez Valladares, Paloma, Rojas Noboa, Johanna Carolina, Kestler, Krysta, Duro Millán, Rafael“…RESULTS: During follow-up there were 72 disease-related deaths. The 5-years OS for the whole group was 51%. …”
Publicado 2016
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257130por Bonaventure, Audrey, Harewood, Rhea, Stiller, Charles A, Gatta, Gemma, Clavel, Jacqueline, Stefan, Daniela C, Carreira, Helena, Spika, Devon, Marcos-Gragera, Rafael, Peris-Bonet, Rafael, Piñeros, Marion, Sant, Milena, Kuehni, Claudia E, Murphy, Michael F G, Coleman, Michel P, Allemani, Claudia“…We estimated 5-year net survival (ie, the probability of surviving at least 5 years after diagnosis, after controlling for deaths from other causes [background mortality]) for children by calendar period of diagnosis (1995–99, 2000–04, and 2005–09), sex, and age at diagnosis (<1, 1–4, 5–9, and 10–14 years, inclusive) using appropriate life tables. …”
Publicado 2017
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257131por Pearson-Stuttard, Jonathan, Bandosz, Piotr, Rehm, Colin D., Penalvo, Jose, Whitsel, Laurie, Gaziano, Tom, Conrad, Zach, Wilde, Parke, Micha, Renata, Lloyd-Williams, Ffion, Capewell, Simon, Mozaffarian, Dariush, O’Flaherty, Martin“…Among the individual policy scenarios, a national 10% F&V subsidy was projected to be most beneficial, potentially resulting in approximately 150,500 (95% uncertainty interval [UI] 141,400–158,500) CVD deaths prevented or postponed (DPPs) by 2030 in the US. …”
Publicado 2017
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257132“…BACKGROUND: Tobacco use is one of the leading causes of preventable deaths and has become a significant public health issue. …”
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257133por Katapodi, Maria C, Viassolo, Valeria, Caiata-Zufferey, Maria, Nikolaidis, Christos, Bührer-Landolt, Rosmarie, Buerki, Nicole, Graffeo, Rossella, Horváth, Henrik Csaba, Kurzeder, Christian, Rabaglio, Manuela, Scharfe, Michael, Urech, Corinne, Erlanger, Tobias E, Probst-Hensch, Nicole, Heinimann, Karl, Heinzelmann-Schwarz, Viola, Pagani, Olivia, Chappuis, Pierre O“…Genetic services (counseling and testing) for hereditary susceptibility to cancer can prevent many cancer diagnoses and deaths through early identification and risk management. …”
Publicado 2017
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257134por Shahin, Mohammady, Obeid, Slayman, Hamed, Lotfy, Templin, Christian, Gamperli, Oliver, Nietlispach, Fabian, Maier, Willbald, Yousif, Nooraldaem, Mach, Francois, Roffi, Marco, Windecker, Stephan, Raber, Lorenz, Matter, Christian M., Luscher, Thomas F.“…Similarly, in these patients, cardiac deaths at 0 day (0.8% vs. 0.6% in < 1 h; P = 0.035) and at 30 days (0.8% vs. 0.6% in < 1 h; P = 0.035) were higher as were major adverse cardiovascular events (MACCE) at 0 day (1.4% vs. 0.8% in < 1 h; P = 0.004). …”
Publicado 2017
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257135Publicado 2017“…METHODS: Using all available data sources, the India State-level Disease Burden Initiative estimated burden (metrics were deaths, disability-adjusted life-years [DALYs], prevalence, incidence, and life expectancy) from 333 disease conditions and injuries and 84 risk factors for each state of India from 1990 to 2016 as part of GBD 2016. …”
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257136por Sinharay, Rudy, Gong, Jicheng, Barratt, Benjamin, Ohman-Strickland, Pamela, Ernst, Sabine, Kelly, Frank J, Zhang, Junfeng (Jim), Collins, Peter, Cullinan, Paul, Chung, Kian Fan“…BACKGROUND: Long-term exposure to pollution can lead to an increase in the rate of decline of lung function, especially in older individuals and in those with chronic obstructive pulmonary disease (COPD), whereas shorter-term exposure at higher pollution levels has been implicated in causing excess deaths from ischaemic heart disease and exacerbations of COPD. …”
Publicado 2018
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257137por Iveson, Timothy J, Kerr, Rachel S, Saunders, Mark P, Cassidy, Jim, Hollander, Niels Henrik, Tabernero, Josep, Haydon, Andrew, Glimelius, Bengt, Harkin, Andrea, Allan, Karen, McQueen, John, Scudder, Claire, Boyd, Kathleen Anne, Briggs, Andrew, Waterston, Ashita, Medley, Louise, Wilson, Charles, Ellis, Richard, Essapen, Sharadah, Dhadda, Amandeep S, Harrison, Mark, Falk, Stephen, Raouf, Sherif, Rees, Charlotte, Olesen, Rene K, Propper, David, Bridgewater, John, Azzabi, Ashraf, Farrugia, David, Webb, Andrew, Cunningham, David, Hickish, Tamas, Weaver, Andrew, Gollins, Simon, Wasan, Harpreet S, Paul, James“…Peripheral neuropathy of grade 2 or worse was more common in the 6 month group (237 [58%] of 409 patients for the subset with safety data) than in the 3 month group (103 [25%] of 420) and was long-lasting and associated with worse quality of life. 1098 serious adverse events were reported (492 reports in the 3 month group and 606 reports in the 6 month group) and 32 treatment-related deaths occurred (16 in each group). INTERPRETATION: In the whole study population, 3 months of oxaliplatin-containing adjuvant chemotherapy was non-inferior to 6 months of the same therapy for patients with high-risk stage II and stage III colorectal cancer and was associated with reduced toxicity and improved quality of life. …”
Publicado 2018
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257138por Mendes, Diego, Mustafé, Gustavo, Fernandes, Thalita, Martins, Thais, Dantas, Clarissa“…RESULTS: Until now, of the 49 patients, 2 dropped out treatment, 8 had been transferred to other services, 5 refused to participate, 1 had the diagnostic changed to bipolar disorder and 3 had died precociously. Of the deaths, 1 was due to complications secondary to the use of clozapine, 1 due to suicide and 1 patient was murdered by another patient during a psychiatric hospitalization. …”
Publicado 2018
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257139por Rasella, Davide, Basu, Sanjay, Hone, Thomas, Paes-Sousa, Romulo, Ocké-Reis, Carlos Octávio, Millett, Christopher“…With the maintenance of the levels of social protection provided by the BFP and ESF, in the most likely economic crisis scenario the U5MR is expected to be 8.57% (95% CI: 6.88%–10.24%) lower in 2030 than under fiscal austerity—a cumulative 19,732 (95% CI: 10,207–29,285) averted under-five deaths between 2017 and 2030. U5MRs from diarrhoea, malnutrition, and lower respiratory tract infections are projected to be 39.3% (95% CI: 36.9%–41.8%), 35.8% (95% CI: 31.5%–39.9%), and 8.5% (95% CI: 4.1%–12.0%) lower, respectively, in 2030 under the maintenance of BFP and ESF coverage, with 123,549 fewer under-five hospitalisations from all causes over the study period. …”
Publicado 2018
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257140por Griffin, Damian R, Dickenson, Edward J, Wall, Peter D H, Achana, Felix, Donovan, Jenny L, Griffin, James, Hobson, Rachel, Hutchinson, Charles E, Jepson, Marcus, Parsons, Nick R, Petrou, Stavros, Realpe, Alba, Smith, Joanna, Foster, Nadine E“…There were no treatment-related deaths, but one patient in the hip arthroscopy group developed a hip joint infection after surgery. …”
Publicado 2018
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