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  1. 257281
    “…BACKGROUND: Neonatal deaths contribute to nearly half (47%) of under-five mortality globally and 67% in Bangladesh. …”
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    Mother's care-seeking behavior for neonatal danger signs from qualified providers in rural Bangladesh: A generalized structural equation modeling and mediation analysis
  2. 257282
    “…Seventeen participants (5.8% in V114 group, 6.7% in PCV13 group) died during the study. None of the deaths was determined by the investigator to be related to study vaccines. …”
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    P07 A Phase 3 randomized, double-blind, comparator-controlled study to evaluate safety, tolerability and immunogenicity of V114 pneumococcal vaccine in haematopoietic cell transplant recipients (PNEU-STEM)
  3. 257283
    “…BACKGROUND: Sudden Unexpected Infant Deaths (SUID) can occur between 1 month and 1 year of age and are inequitably distributed with a greater burden in populations with numerous health disparities. …”
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    The provision of the baby box was associated with safe sleep practices in a low-resource community: a randomized control trial in Ecuador
  4. 257284
    “…BACKGROUND: Gastric cancer peritoneal metastasis (GCPM) is an important cause of cancer-related deaths worldwide. Long non-coding RNAs (lncRNAs) play a key role in the regulation of GCPM, but the underlying mechanisms have not been elucidated. …”
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    Identification and validation of crucial lnc-TRIM28-14 and hub genes promoting gastric cancer peritoneal metastasis
  5. 257285
    “…BACKGROUND: Gastric cancer (GC) is a leading cause of cancer-related deaths worldwide. Specific and thorough identification of cancer cell subsets with higher tumorigenicity and chemoresistance, such as cancer stem cells (CSCs), could lead to the development of new and promising therapeutic targets. …”
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    CD24+CD44+CD54+EpCAM+ gastric cancer stem cells predict tumor progression and metastasis: clinical and experimental evidence
  6. 257286
    “…IMPORTANCE: Neuroblastoma accounts for 12% of childhood cancer deaths. The genetic contribution of rare pathogenic germline variation in patients without a family history remains unclear. …”
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    Germline pathogenic variants in 786 neuroblastoma patients
  7. 257287
    “…BACKGROUND: Aspiration pneumonitis remains a dreaded complication that may lead to almost 9% of anaesthesia-related deaths. The presence of gastric contents has always been a contributing factor to an increased risk of aspiration. …”
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    Assessment of residual gastric volume using point-of-care ultrasonography in adult patients who underwent elective surgery
  8. 257288
    “…BACKGROUND: With prevalence up to 4%, Ventricular Septal Defect (VSD) is one of the leading causes of neonatal deaths. VSD is a common complex genetic disorder that has been associated with many genetic determinants. …”
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    Genetic studies in the Pakistani population reveal novel associations with ventricular septal defects (VSDs)
  9. 257289
    “…Functional MRI indicated stronger connectivity at Weeks 26 and 52 relative to baseline between a broadly distributed set of brain regions in patients with venglustat exposure and biomarker reduction but not Patient 9, although neurocognition, assessed by Vineland II, deteriorated in all domains over time, which illustrates disease progression despite the intervention. There were no deaths, serious adverse events or discontinuations. …”
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    Venglustat combined with imiglucerase for neurological disease in adults with Gaucher disease type 3: the LEAP trial
  10. 257290
    “…Overall, 141 patients (53.6%) had TEAEs, which were mostly mild to moderate and gastrointestinal. There were 8 deaths (3.0%) and 33 patients (12.5%) with serious TEAEs; none were considered treatment related by the investigators. …”
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    Safety and Tolerability of SER-109 as an Investigational Microbiome Therapeutic in Adults With Recurrent Clostridioides difficile Infection: A Phase 3, Open-Label, Single-Arm Trial
  11. 257291
    “…Outcomes at Week 8 for vixarelimab versus placebo included LS-mean PCFB in WI-NRS score, −50.6% versus −29.4% (LS-mean difference [95% CI], −21.2% [−40.82, −1.60]; p = 0.03); ≥4-point reduction in WI-NRS score, 52.2% (12/23) versus 30.8% (8/26) (p = 0.11); PN-IGA score of 0 or 1, 30.4% (7/23) versus 7.7% (2/26) (p = 0.03); LS-mean PCFB in pruritus VAS score, −54.4% versus −32.6% (p = 0.03); and LS-mean PCFB sleep loss reduction (improvement), −56.3% versus −30.0% (p = 0.02). No deaths, serious TEAEs, or TEAEs leading to dose interruption were reported. …”
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    Efficacy and safety of vixarelimab, a human monoclonal oncostatin M receptor β antibody, in moderate-to-severe prurigo nodularis: a randomised, double-blind, placebo-controlled, phase 2a study
  12. 257292
    “…Incentive schemes have been effective in improving health workers’ performance thereby reducing maternal and child deaths. The efficiency of public health services in most developing countries has been linked to the provision of incentives. …”
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    How different incentives influence reported motivation and perceptions of performance in Ghanaian community-based health planning and services zones
  13. 257293
    “…Colorectal cancer (CRC), one of the leading causes of cancer-related deaths in the western world, is the third most common cancer for both men and women. …”
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    DNA Methylation and Gene Expression of the Cysteinyl Leukotriene Receptors as a Prognostic and Metastatic Factor for Colorectal Cancer Patients
  14. 257294
    por Jehan, Fyezah, Sazawal, Sunil, Baqui, Abdullah H., Nisar, Muhammad Imran, Dhingra, Usha, Khanam, Rasheda, Ilyas, Muhammad, Dutta, Arup, Mitra, Dipak K., Mehmood, Usma, Deb, Saikat, Mahmud, Arif, Hotwani, Aneeta, Ali, Said Mohammed, Rahman, Sayedur, Nizar, Ambreen, Ame, Shaali Makame, Moin, Mamun Ibne, Muhammad, Sajid, Chauhan, Aishwarya, Begum, Nazma, Khan, Waqasuddin, Das, Sayan, Ahmed, Salahuddin, Hasan, Tarik, Khalid, Javairia, Rizvi, Syed Jafar Raza, Juma, Mohammed Hamad, Chowdhury, Nabidul Haque, Kabir, Furqan, Aftab, Fahad, Quaiyum, Abdul, Manu, Alexander, Yoshida, Sachiyo, Bahl, Rajiv, Rahman, Anisur, Pervin, Jesmin, Winston, Jennifer, Musonda, Patrick, Stringer, Jeffrey S. A., Litch, James A., Ghaemi, Mohammad Sajjad, Moufarrej, Mira N., Contrepois, Kévin, Chen, Songjie, Stelzer, Ina A., Stanley, Natalie, Chang, Alan L., Hammad, Ghaith Bany, Wong, Ronald J., Liu, Candace, Quaintance, Cecele C., Culos, Anthony, Espinosa, Camilo, Xenochristou, Maria, Becker, Martin, Fallahzadeh, Ramin, Ganio, Edward, Tsai, Amy S., Gaudilliere, Dyani, Tsai, Eileen S., Han, Xiaoyuan, Ando, Kazuo, Tingle, Martha, Marić, Ivana, Wise, Paul H., Winn, Virginia D., Druzin, Maurice L., Gibbs, Ronald S., Darmstadt, Gary L., Murray, Jeffrey C., Shaw, Gary M., Stevenson, David K., Snyder, Michael P., Quake, Stephen R., Angst, Martin S., Gaudilliere, Brice, Aghaeepour, Nima
    Publicado 2020
    “…IMPORTANCE: Worldwide, preterm birth (PTB) is the single largest cause of deaths in the perinatal and neonatal period and is associated with increased morbidity in young children. …”
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    Multiomics Characterization of Preterm Birth in Low- and Middle-Income Countries
  15. 257295
    por Palmer, Suetonia C, Tendal, Britta, Mustafa, Reem A, Vandvik, Per Olav, Li, Sheyu, Hao, Qiukui, Tunnicliffe, David, Ruospo, Marinella, Natale, Patrizia, Saglimbene, Valeria, Nicolucci, Antonio, Johnson, David W, Tonelli, Marcello, Rossi, Maria Chiara, Badve, Sunil V, Cho, Yeoungjee, Nadeau-Fredette, Annie-Claire, Burke, Michael, Faruque, Labib I, Lloyd, Anita, Ahmad, Nasreen, Liu, Yuanchen, Tiv, Sophanny, Millard, Tanya, Gagliardi, Lucia, Kolanu, Nithin, Barmanray, Rahul D, McMorrow, Rita, Raygoza Cortez, Ana Karina, White, Heath, Chen, Xiangyang, Zhou, Xu, Liu, Jiali, Rodríguez, Andrea Flores, González-Colmenero, Alejandro Díaz, Wang, Yang, Li, Ling, Sutanto, Surya, Solis, Ricardo Cesar, Díaz González-Colmenero, Fernando, Rodriguez-Gutierrez, René, Walsh, Michael, Guyatt, Gordon, Strippoli, Giovanni F M
    Publicado 2021
    “…The absolute benefits of these drugs vary substantially across patients from low to very high risk of cardiovascular and renal outcomes (eg, SGLT-2 inhibitors resulted in 3 to 40 fewer deaths in 1000 patients over five years; see interactive decision support tool (https://magicevidence.org/match-it/200820dist/#!…”
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    Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials
  16. 257296
    por Ashraf, Sohaib, Ashraf, Shoaib, Akmal, Rutaba, Ashraf, Moneeb, Kalsoom, Larab, Maqsood, Aadil, Imran, Muhammad Ahmad, Farooq, Iqra, Ashraf, Sidra, Siddiqui, Uzma Nasim, Ghufran, Muhammad, Akram, Muhammad Kiwan, Majeed, Nighat, Rafique, Sundas, Habib, Zaigham, Shahab, Muhammad Sarmad, Akmal, Adeen, Shaukat, Zeeshan, Abdin, Zain ul, Khaqan, Ayesha, Arshad, Shahroze, Rehman Virk, Muhammad Abdul, Gul, Mehak, Awais, Abeer bin, Hassan, Muhammad, Khalid, Noman, Iqbal, Qurrat Ul Ain, Ahmad, Tausif, Akram, Muaaz, Muhammad, Ameer, Khalil, Musa, Aslam, Aneeq, Umer, Muhammad, Sherazi, Syed Sami Hussain, Safdar, Zartasha, Ahmad, Sohail, Bilal, Muhammad, Zahid, Muhammad Nauman, Koshak, Abdulrahman E., Hilal, Abubakar, Malik, Ahmad Azam, Iqbal, Usman, Baig, Atif Amin, Alahmadi, Yaser Masuod, Humayun, Ayesha, Malik, Amber, Ahmad, Ali, Ashraf, Muhammad, Saboor, Qazi Abdul, Izhar, Mateen
    Publicado 2021
    “…Secondary endpoints include incidence of COVID-19-related symptoms, hospitalizations, and deaths along with the severity of COVID-19-related symptoms till 14(th) day of randomization. …”
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    Prophylactic potential of honey and Nigella sativa L. against hospital and community-based SARS-CoV-2 spread: a structured summary of a study protocol for a randomised controlled trial
  17. 257297
    “…Estimated models projected over 150,000 deaths and 4,600,000 hospitalizations in the first year of the disease in the absence of adequate interventions. …”
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    Leveraging Polio Geographic Information System Platforms in the African Region for Mitigating COVID-19 Contact Tracing and Surveillance Challenges: Viewpoint
  18. 257298
    “…According to the statistics by the Global Health Estimates, chronic illnesses contribute by 71% to total deaths in the Arab region. While chronic illnesses have been demonstrated to carry high levels of social stigma, it is only recently that little research attention has been given to this topic in the Arab world. …”
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    Measuring public attitudes towards people living with chronic diseases in Arabic-speaking populations: adaptation and development of the Social Stigma Scale of Chronic Diseases (SSS-CD)
  19. 257299
    “…We aimed to investigate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody prevalence by city and according to sex, age, ethnicity group, and socioeconomic status, and compare seroprevalence estimates with official statistics on deaths and cases. METHODS: In this repeated cross-sectional study, we did two seroprevalence surveys in 133 sentinel cities in all Brazilian states. …”
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    SARS-CoV-2 antibody prevalence in Brazil: results from two successive nationwide serological household surveys
  20. 257300
    por Feigin, Valery L., Vos, Theo, Alahdab, Fares, Amit, Arianna Maever L., Bärnighausen, Till Winfried, Beghi, Ettore, Beheshti, Mahya, Chavan, Prachi P., Criqui, Michael H., Desai, Rupak, Dhamminda Dharmaratne, Samath, Dorsey, E. Ray, Wilder Eagan, Arielle, Elgendy, Islam Y., Filip, Irina, Giampaoli, Simona, Giussani, Giorgia, Hafezi-Nejad, Nima, Hole, Michael K., Ikeda, Takayoshi, Owens Johnson, Catherine, Kalani, Rizwan, Khatab, Khaled, Khubchandani, Jagdish, Kim, Daniel, Koroshetz, Walter J., Krishnamoorthy, Vijay, Krishnamurthi, Rita V., Liu, Xuefeng, Lo, Warren David, Logroscino, Giancarlo, Mensah, George A., Miller, Ted R., Mohammed, Salahuddin, Mokdad, Ali H., Moradi-Lakeh, Maziar, Morrison, Shane Douglas, Shivamurthy, Veeresh Kumar N., Naghavi, Mohsen, Nichols, Emma, Norrving, Bo, Odell, Christopher M., Pupillo, Elisabetta, Radfar, Amir, Roth, Gregory A., Shafieesabet, Azadeh, Sheikh, Aziz, Sheikhbahaei, Sara, Shin, Jae Il, Singh, Jasvinder A., Steiner, Timothy J., Stovner, Lars Jacob, Wallin, Mitchell Taylor, Weiss, Jordan, Wu, Chenkai, Zunt, Joseph Raymond, Adelson, Jaimie D., Murray, Christopher J. L.
    Publicado 2020
    “…Exceptions for this trend included traumatic brain injury incidence (−29.1% [95% UI, −32.4% to −25.8%]); spinal cord injury prevalence (−38.5% [95% UI, −43.1% to −34.0%]); meningitis prevalence (−44.8% [95% UI, −47.3% to −42.3%]), deaths (−64.4% [95% UI, −67.7% to −50.3%]), and DALYs (−66.9% [95% UI, −70.1% to −55.9%]); and encephalitis DALYs (−25.8% [95% UI, −30.7% to −5.8%]). …”
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    Burden of Neurological Disorders Across the US From 1990-2017: A Global Burden of Disease Study
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