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3921“…Necrosis, one of the two main types of cell death, contributes critically in many devastating pathological conditions in human, including stroke, ischemia, trauma and neurodegenerative diseases. …”
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3922
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3923
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3924por Deng, Longfei, Lei, Yunlong, Liu, Rui, Li, Jingyi, Yuan, Kefei, Li, Yi, Chen, Yi, Liu, Yi, Lu, You, Edwards III, Carl K, Huang, Canhua, Wei, Yuquan“…Moreover, the combination of pyrvinium with autophagy stimuli improves its toxicity against cancer cells, and pretreatment of cells with 3-MA or siBeclin1 partially protects cells from pyrvinium-induced cell death under glucose starvation, suggesting that targeted autophagy addiction is involved in pyrvinium-mediated cytotoxicity. …”
Publicado 2013
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3925“…The leading cause of line-of-duty mortality is sudden cardiac death, which accounts for approximately 45% of all firefighter duty-related fatalities. …”
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3926
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3927
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3928“…Brain ischemia often results in neuronal necrosis, which may spread death to neighboring cells. However, the molecular events of neuronal necrosis and the mechanisms of this spreading death are poorly understood due to the limited genetic tools available for deciphering complicated responses in mammalian brains. …”
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3929“…We propose that if strategies could be devised which would favor the death of all cells which HIV infects, or if all latently infected cells that release HIV would succumb to viral-induced cytotoxicity, then these approaches combined with effective ART to prevent spreading infection, would together result in a cure for HIV. …”
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3930“…Recent studies have shown that mutations in the adenine nucleotide translocase (Ant) cause aging-dependent degenerative cell death (DCD) in yeast, which is sequentially manifested by inner membrane stress, mitochondrial DNA (mtDNA) loss, and progressive loss of cell viability. …”
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3931
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3932“…The growth of the juvenile spikes has been frequently considered the determinant of grain number, implying that floret development would depend on resource availability and that the onset of floret death would be related to spike growth. However, this model has been recently challenged from a study concluding that floret death started when the most advanced floret primordia reached a particular developmental stage. …”
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3933por Nair, Syam, Hagberg, Henrik, Krishnamurthy, Rajanikant, Thornton, Claire, Mallard, Carina“…DAPk1 also mediate a range of activities from autophagy, membrane blebbing and DNA fragmentation ultimately leading to cell death. DAPk mRNA levels are particularly highly expressed in the developing brain and thus, we hypothesize that DAPk1 may play a role in perinatal brain injury. …”
Publicado 2013
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3934por Friesen, Claudia, Roscher, Mareike, Hormann, Inis, Fichtner, Iduna, Alt, Andreas, Hilger, Ralf A., Debatin, Klaus-Michael, Miltner, Erich“…Cyclic AMP (cAMP) regulates a number of cellular processes and modulates cell death induction. cAMP levels are altered upon stimulation of specific G-protein-coupled receptors inhibiting or activating adenylyl cyclases. …”
Publicado 2013
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3935“…Here, we report a case cefuroxime-induced disulfiram-like reaction which led to sudden death of the patient.…”
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3937por Mok, Yejin, Won, Soyoung, Kimm, Heejin, Nam, Chungmo, Ohrr, Heechoul, Jee, Sun Ha“…BACKGROUND: Physical activity decreases deaths from cardiovascular disease and other causes; however, it is unclear whether physical activity is associated with cancer incidence and death in Asian populations. …”
Publicado 2012
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3938“…A sigma-2 receptor agonist siramesine has been shown to trigger cell death of cancer cells and to exhibit a potent anticancer activity in vivo. …”
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3939por Ghooi, Ravindra. B.“…These addressed the issues of compensation of injury and death in clinical trials in addition to the role and registration of Ethics Committees. …”
Publicado 2013
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3940