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61por Kanabus, Marta, Fassone, Elisa, Hughes, Sean David, Bilooei, Sara Farahi, Rutherford, Tricia, Donnell, Maura O’, Heales, Simon J. R., Rahman, Shamima“…This study focusses on decanoic acid (C10), a component of the medium chain triglyceride KD, and a ligand for the nuclear receptor PPAR-γ known to be involved in mitochondrial biogenesis. …”
Publicado 2016
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62por Selakovic, Dragica, Joksimovic, Jovana, Zaletel, Ivan, Puskas, Nela, Matovic, Milovan, Rosic, Gvozden“…The aim of this study was to evaluate the behavioral effects of chronic (six weeks) nandrolone decanoate (ND, 20 mg/kg, s.c., weekly in single dose) administration (in order to mimic heavy human abuse), and exercise (swimming protocol of 60 minutes a day, five days in a row/two days break), applied alone and simultaneously with ND, in male rats (n = 40). …”
Publicado 2017
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63por Bai, Ying, Shi, Xu-Bo, Zhang, Yu-Qiong, Wang, Yue-Li, Liu, Xin-Yao, Esteve-Pastor, María Asunción“…We investigated the differences of MMP-2 expression between LV and RV in response to nandrolone decanoate (ND), swimming training (ST), and combined ND and ST (NS) in mice, based on their structural, functional, and biochemical characteristics. …”
Publicado 2018
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64por Saddick, Salina Y.“…Nandrolone decanoate (Nd) is a highly abused androgenic-anabolic steroid among body builders. …”
Publicado 2021
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66por Yang, Min Hee, Lee, Mina, Deivasigamani, Amudha, Le, Duc Dat, Mohan, Chakrabhavi Dhananjaya, Hui, Kam Man, Sethi, Gautam, Ahn, Kwang Seok“…Herein, we have examined the anti-neoplastic effects of decanoic acid (DA) in hepatocellular carcinoma cells and in vivo mouse models. …”
Publicado 2023
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67“…A random trial in which cyclophosphamide, nandrolone decanoate and the two drugs in combination were used in the treatment of advanced breast carcinoma is described. …”
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68“…OBJECTIVE: This study was conducted to assay the effect of Nandrolone Decanoate (ND) on the testis and testosterone concentration in male immature rats compare with mature ones in short and long time. …”
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69por Damiano, Fabrizio, De Benedetto, Giuseppe E., Longo, Serena, Giannotti, Laura, Fico, Daniela, Siculella, Luisa, Giudetti, Anna M.“…In this study, with a gas chromatography-mass spectrometry (GC-MS)-based metabolomics approach, coupled with multivariate data analyses, we followed the metabolic changes of U87MG glioblastoma cells after the addition of octanoic (C8), or decanoic (C10) acids for 24 h. Our analysis highlighted significant differences in the metabolism of U87MG cells after the addition of C8 or C10 and identified several metabolites whose amount changed between the two groups of treated cells. …”
Publicado 2020
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70“…HT22 hippocampal murine neurons were incubated with two important KD metabolites–beta-hydroxybutyrate (BHB) (the predominant ketone body) and decanoic acid (C10), both accumulating under KD. Enzyme activity, protein, and gene expressions of SIRT 1-4, enzyme capacities of the mitochondrial respiratory chain complexes (MRC), citrate synthase (CS) and gene expression of monocarboxylate transporters were measured in control (untreated) and KD-treated cells. …”
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71“…Although the intake of each MCT type (octanoate; C8:0, decanoate; C10:0, and dodecanoate; C12:0) exhibits beneficial metabolic effects, individual functional differences remain unclear. …”
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72“…By using IF patient-derived intestinal organoids and Caco-2 cells as in vitro models, we demonstrated that the supplementation of decanoic acid (DA) could significantly induce the expression of KLF4 along with SLC6A4 and SLC7A9, suggesting that DA may function as a potential therapeutic strategy to promote cell maturation and functional improvement. …”
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73“…We show that PDE7B serves as a catalyst of the hydrolysis of testosterone enanthate and nandrolone decanoate in liver cytosol. The gene expression of PDE7B was significantly induced 3- and 5- fold after 2 h exposure to 1 μM testosterone enanthate and nandrolone decanoate, respectively. …”
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74por Gopal, Srihari, Berwaerts, Joris, Nuamah, Isaac, Akhras, Kasem, Coppola, Danielle, Daly, Ella, Hough, David, Palumbo, Joseph“…BACKGROUND: We analyzed data retrieved through a PubMed search of randomized, placebo-controlled trials of first-generation antipsychotic long-acting injectables (haloperidol decanoate, bromperidol decanoate, and fluphenazine decanoate), and a company database of paliperidone palmitate, to compare the benefit-risk ratio in patients with schizophrenia. …”
Publicado 2011
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75por Noguchi, Yuna, Matsuzawa, Nichiwa, Akama, Youichi, Sekiguchi, Kenta, Takehana, Shiori, Shimazu, Yoshihito, Takeda, Mamoru“…BACKGROUND: Although decanoic acid (DA) is thought to act as a muscarinic cholinergic agonist, effect of DA on nociceptive behavioral responses and the excitability of nociceptive neuronal activity under in vivo conditions remain to be determined. …”
Publicado 2017
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77por Mesbah, Fakhroddin, Bordbar, Hossein, Talaei Khozani, Tahereh, Dehghani, Farzaneh, Mirkhani, Hossein“…BACKGROUND: The follicular growth and development may be affected by abused drugs. Nandrolone decanoate (ND) as an anabolic androgenic steroid can damage the morphological and functional features of the ovary and may lead to reproductive failure. …”
Publicado 2018
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78por Andersen, Jens V., Westi, Emil W., Jakobsen, Emil, Urruticoechea, Nerea, Borges, Karin, Aldana, Blanca I.“…The medium-chain fatty acids octanoic acid (C8) and decanoic acid (C10) are gaining attention as beneficial brain fuels in several neurological disorders. …”
Publicado 2021
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79por Sanguanphun, Tanatcha, Sornkaew, Nilubon, Malaiwong, Nawaphat, Chalorak, Pawanrat, Jattujan, Prapaporn, Niamnont, Nakorn, Sobhon, Prasert, Meemon, Krai“…Chemical analysis demonstrated that HLEA-P1 compound is decanoic acid/capric acid. Taken together, our findings revealed that decanoic acid isolated from H. leucospilota exerts anti-Parkinson effect in C. elegans PD models by partly modulating IIS/DAF-16 pathway.…”
Publicado 2022
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80por Hassan, Dalia Abd Elwahab, Ghaleb, Sherien S., Zaki, Amr reda, Abdelmenem, Ahmed, Nabil, Shimaa, Alim, Mostafa Abdallah Abdel“…METHODS: Our research was done on 120 male albino rats that were allocated into 6 groups; group I: Served as a control group, group II: Received the anabolic steroid Nandrolone Decanoate, group III: Received silymarin orally, group IV: Received fenugreek seeds extract orally, group (V): Received the anabolic steroid Nandrolone Decanoate and silymarin and group (VI): Received the anabolic steroid Nandrolone Decanoate and fenugreek seeds extract. …”
Publicado 2023
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