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Diabetes
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2701Publicado 1996“…Diabetes in nonobese diabetic (NOD) mice is a T cell-dependent autoimmune disease. …”
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2702“…To investigate the role of NK T cells in autoimmune diabetes, we crossed CD1 knockout (CD1KO) mutation onto the nonobese diabetic (NOD) genetic background. …”
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2703por Imai, Saeko, Kozai, Hana, Matsuda, Mikuko, Hasegawa, Goji, Obayashi, Hiroshi, Togawa, Chikako, Yamamura, Toyomi, Watanabe, Kanji, Miyatani, Syuichi, Yoshikawa, Toshikazu, Kajiyama, Shizuo“…The aim of this study was to investigate the effects of a diabetic meal delivery system on glycemic control over a 12 month period in patients with type 2 diabetes. …”
Publicado 2008
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2704por Usuki, Seigo, Ito, Yukihiko, Morikawa, Keiko, Kise, Mitsuo, Ariga, Toshio, Rivner, Michael, Yu, Robert K“…BACKGROUND: To study the effects of a pre-germinated brown rice diet (PR) on diabetic neuropathy in streptozotocin (STZ)-induced diabetic rats. …”
Publicado 2007
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2705por Krishnaveni, Ghattu V., Hill, Jacqueline C., Veena, Sargoor R., Geetha, Suguna, Jayakumar, Magudilu N., Karat, Chitra L.S., Fall, Caroline H.D.“…This study was carried out to examine the incidence of diabetes and the factors associated with this in a cohort of South Indian women 5 years after they were examined for gestational diabetes (GDM). …”
Publicado 2007
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2706“…The Spontaneously Diabetic Torii (SDT) rat, a newly established animal model for diabetes mellitus, presents nonobese type 2 diabetes with ocular complications. …”
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2707Extension of Type 2 Diabetes Genome-Wide Association Scan Results in the Diabetes Prevention Programpor Moore, Allan F., Jablonski, Kathleen A., McAteer, Jarred B., Saxena, Richa, Pollin, Toni I., Franks, Paul W., Hanson, Robert L., Shuldiner, Alan R., Knowler, William C., Altshuler, David, Florez, Jose C.“…OBJECTIVE— Genome-wide association scans (GWASs) have identified novel diabetes-associated genes. We evaluated how these variants impact diabetes incidence, quantitative glycemic traits, and response to preventive interventions in 3,548 subjects at high risk of type 2 diabetes enrolled in the Diabetes Prevention Program (DPP), which examined the effects of lifestyle intervention, metformin, and troglitazone versus placebo. …”
Publicado 2008
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2708por Wu, Jin-Shang, Yang, Yi-Ching, Lu, Feng-Hwa, Wu, Chih-Hsing, Wang, Ru-Hsueh, Chang, Chih-Jen“…OBJECTIVE—The aim of this study was to investigate the relationship between pre-diabetes and orthostatic hypotension and to examine the prevalence and correlates of orthostatic hypotension in community dwellers with normal glucose tolerance (NGT), pre-diabetes, and diabetes. …”
Publicado 2009
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2709por Bonfanti, Riccardo, Colombo, Carlo, Nocerino, Valentina, Massa, Ornella, Lampasona, Vito, Iafusco, Dario, Viscardi, Matteo, Chiumello, Giuseppe, Meschi, Franco, Barbetti, Fabrizio“…The aim of our study was to screen for the insulin gene in patients who had been clinically classified as type 1 diabetic but who tested negative for type 1 diabetes autoantibodies. …”
Publicado 2009
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2710por Mayer-Davis, Elizabeth J., Beyer, Jennifer, Bell, Ronny A., Dabelea, Dana, D'Agostino, Ralph, Imperatore, Giuseppina, Lawrence, Jean M., Liese, Angela D., Liu, Lenna, Marcovina, Santica, Rodriguez, Beatriz“…Characteristics of these youth were obtained during a research visit for 436 African American youth with type 1 diabetes and 212 African American youth with type 2 diabetes. …”
Publicado 2009
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2711“…Recent clinical evidence suggests important role of lipid and amino acid metabolism in early pre-autoimmune stages of type 1 diabetes pathogenesis. We study the molecular paths associated with the incidence of insulitis and type 1 diabetes in the Non-Obese Diabetic (NOD) mouse model using available gene expression data from the pancreatic tissue from young pre-diabetic mice. …”
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2712por Parker, Matthew J., Xue, Song, Alexander, John J., Wasserfall, Clive H., Campbell-Thompson, Martha L., Battaglia, Manuela, Gregori, Silvia, Mathews, Clayton E., Song, Sihong, Troutt, Misty, Eisenbeis, Scott, Williams, John, Schatz, Desmond A., Haller, Michael J., Atkinson, Mark A.“…OBJECTIVE: The autoimmune destruction of β-cells in type 1 diabetes results in a loss of insulin production and glucose homeostasis. …”
Publicado 2009
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2714por Hovnik, Tinka, Dolžan, Vita, Bratina, Nataša Uršič, Podkrajšek, Katarina Trebušak, Battelino, Tadej“…OBJECTIVE: Oxidative stress plays an important role in the development of microangiopathic complications in type 1 diabetes. We investigated polymorphic markers in genes encoding enzymes regulating production of reactive oxygen species in association with diabetic retinopathy or diabetic nephropathy. …”
Publicado 2009
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2715por Orban, Tihamer, Sosenko, Jay M., Cuthbertson, David, Krischer, Jeffrey P., Skyler, Jay S., Jackson, Richard, Yu, Liping, Palmer, Jerry P., Schatz, Desmond, Eisenbarth, George“…Thus, we studied the extent to which specific autoantibodies are predictive of type 1 diabetes. RESEARCH DESIGN AND METHODS: Two cohorts were derived from the first screening for islet cell autoantibodies (ICAs) in the Diabetes Prevention Trial–Type 1 (DPT-1). …”
Publicado 2009
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2716por Larsen, Nadja, Vogensen, Finn K., van den Berg, Frans W. J., Nielsen, Dennis Sandris, Andreasen, Anne Sofie, Pedersen, Bente K., Al-Soud, Waleed Abu, Sørensen, Søren J., Hansen, Lars H., Jakobsen, Mogens“…The aim of this study was to assess the differences between the composition of the intestinal microbiota in humans with type 2 diabetes and non-diabetic persons as control. METHODS AND FINDINGS: The study included 36 male adults with a broad range of age and body-mass indices (BMIs), among which 18 subjects were diagnosed with diabetes type 2. …”
Publicado 2010
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2717“…RESEARCH DESIGN AND METHODS: Beliefs about diabetes were assessed among 334 individuals with diabetes living in a primarily low-income, minority, urban neighborhood. …”
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2718“…METHODS: We used data from the 1999-2004 National Health and Nutrition Examination Survey (NHANES) to develop and validate SVM models for two classification schemes: Classification Scheme I (diagnosed or undiagnosed diabetes vs. pre-diabetes or no diabetes) and Classification Scheme II (undiagnosed diabetes or pre-diabetes vs. no diabetes). …”
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2719“…OBJECTIVE: To determine the relationship between subclinical hypothyroidism (SCH) and the prevalence of diabetic retinopathy in type 2 diabetic patients. RESEARCH DESIGN AND METHODS: A total of 1,170 type 2 diabetic patients were screened for thyroid function. …”
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2720“…BACKGROUND: We aimed to determine whether family practices' achievement of diabetes quality of care targets is associated with diabetic retinal disease in registered patients. …”
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