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194921por Trinchese, Giovanna, Cavaliere, Gina, Cimmino, Fabiano, Catapano, Angela, Carta, Gianfranca, Pirozzi, Claudio, Murru, Elisabetta, Lama, Adriano, Meli, Rosaria, Bergamo, Paolo, Banni, Sebastiano, Mollica, Maria Pina“…Conjugated linoleic acid mixture (CLA) exhibited anti-obesity and anti-diabetic effects; however, the modulatory ability of its isomers (cis(9), trans(11), C9; trans(10), cis(12), C10) on the metabolic flexibility in skeletal muscle remains to be demonstrated. …”
Publicado 2020
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194922por Kurosawa, T., Mifune, Y., Inui, A., Nishimoto, H., Ueda, Y., Kataoka, T., Yamaura, K., Mukohara, S., Kuroda, R.“…Apocynin is therefore a potential prodrug in the treatment of diabetic tendinopathy. Cite this article: Bone Joint Res 2020;9(1):23–28.…”
Publicado 2020
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194923“…Of the 47 cases, 57.4% had undergone deferred reconstruction, and 42.6% immediate reconstruction; 27.7% had undergone pre-operative chemotherapy and radiotherapy, 27.7% pre-operative chemotherapy, and 2.1% pre-operative radiotherapy; 6.4% were diabetic, 4.3% active smokers, and more than 50.0% had BMI greater than 25 kg/m(2). …”
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194924por Xu, Renjie, Zhu, Hongdan, Hu, Lingmin, Yu, Beimeng, Zhan, Xiaohua, Yuan, Yichu, Zhou, Ping“…Morroniside is a biologically active polyphenol found in Cornus officinalis Sieb. et Zucc (CO) that exhibits a broad spectrum of pharmacological activities, such as protecting nerves, and preventing diabetic liver damage and renal damage. However, little data are available regarding the mechanism of its intestinal absorption. …”
Publicado 2020
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194925por Alqarihi, Abdullah, Gebremariam, Teclegiorgis, Gu, Yiyou, Swidergall, Marc, Alkhazraji, Sondus, Soliman, Sameh S. M., Bruno, Vincent M., Edwards, John E., Filler, Scott G., Uppuluri, Priya, Ibrahim, Ashraf S.“…Mucormycosis, caused by Rhizopus species, is a life-threatening fungal infection that occurs in patients immunocompromised by diabetic ketoacidosis (DKA), cytotoxic chemotherapy, immunosuppressive therapy, hematologic malignancies, or severe trauma. …”
Publicado 2020
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194926por B. Gowda, Siddabasave Gowda, Fuda, Hirotoshi, Tsukui, Takayuki, Chiba, Hitoshi, Hui, Shu-Ping“…Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are a recently discovered class of biologically active lipids with anti-inflammatory and anti-diabetic properties. Despite the possible link between endogenous FAHFA levels and nuclear factor erythroid 2-related factor 2 (Nrf2), their possible function as antioxidants and the mechanisms involved in this are unknown. …”
Publicado 2020
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194927“…The changes in microvascular compliance are independent factors initiating, driving, and/or exacerbating a plethora of microvascular diseases of the eye including diabetic retinopathy (DR) and vitreoretinopathy, retinopathy of prematurity (ROP), wet age-related macular degeneration (AMD), and neovascular glaucoma. …”
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194928por Yue, Yongfang, Xia, Lili, Xu, Shanshan, Wang, Conghui, Wang, Xinyu, Lu, Weiguo, Xie, Xing“…SURF4 knockdown also inhibited tumorigenesis in nonobese diabetic/severe combined immunodeficiency mice. BIRC3 expression was controlled by SURF4, and BIRC3 showed the similar effect as SURF4 did, and BIRC3 overexpression partially recovered stem-like properties abolished by SURF4 knockdown. …”
Publicado 2020
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194929por Brun, Thierry, Jiménez-Sánchez, Cecilia, Madsen, Jesper Grud Skat, Hadadi, Noushin, Duhamel, Dominique, Bartley, Clarissa, Oberhauser, Lucie, Trajkovski, Mirko, Mandrup, Susanne, Maechler, Pierre“…Collectively, previously published and present data indicate that, in the β-cell, AMPK activation might be implicated in the pre-diabetic state, potentially as a protective mechanism.…”
Publicado 2020
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194930por Chen, Jiawei, Jiang, Quanlong, Xia, Xian, Liu, Kangping, Yu, Zhengqing, Tao, Wanyu, Gong, Wenxuan, Han, Jing‐Dong J.“…Here by analyzing GTEx and other public data in 30 tissues across thousands of individuals, we found a significantly higher level in Asian females, an age‐dependent decrease in all ethnic groups, and a highly significant decrease in type II diabetic patients of ACE2 expression. Consistently, the most significant expression quantitative loci (eQTLs) contributing to high ACE2 expression are close to 100% in East Asians, >30% higher than other ethnic groups. …”
Publicado 2020
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194931“…Presenting best-corrected visual acuity (BCVA) letter score was 45, using the Early Treatment Diabetic Retinopathy Study chart. Past ocular history in the affected, pseudophakic eye included anisometropic amblyopia, but with a documented pre-morbid BCVA of 75 letters. …”
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194932“…Berberine is an isoquinoline alkaloid isolated from various Chinese herbs that has potential of anti-inflammatory, anti-lipidemic, anti-neoplastic, and anti-diabetic activity. In this study, we evaluated the anti-inflammatory efficacy of berberine on allergic airway inflammation by targeting epithelial cells. …”
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194933por Nunes, Valéria Sutti, Bensenor, Isabela M., Lotufo, Paulo A., Passarelli, Marisa, Nakandakare, Edna Regina, Quintão, Eder Carlos Rocha“…In healthy male (n=344), non-obese, non-diabetics, belonging to the city of São Paulo branch of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), we measured in plasma these non-cholesterol sterol markers, together with their anthropometric, dietary parameters, traditional atherosclerotic risk factors, and blood chemistry, coronary arterial calcium score (CAC), and ultrasonographically measured common carotid artery intima-media thickness (CCA-IMT). …”
Publicado 2020
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194934por Ding, Qiongling, Wang, Yanrong, Guo, Pengqian, Li, Jianjun, Chen, Chen, Wang, Ting, Sun, Kai, He, Deyan“…Acetone is a biomarker in the exhaled breath of diabetic patients; sensitive and selective detection of acetone in human exhaled breath plays an important role in noninvasive diagnosis. …”
Publicado 2020
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194935por Arsalan, Muhammad, Baek, Na Rae, Owais, Muhammad, Mahmood, Tahir, Park, Kang Ryoung“…Ophthalmological analysis plays a vital role in the diagnosis of various eye diseases, such as glaucoma, retinitis pigmentosa (RP), and diabetic and hypertensive retinopathy. RP is a genetic retinal disorder that leads to progressive vision degeneration and initially causes night blindness. …”
Publicado 2020
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194936por Cianflone, Eleonora, Torella, Michele, Biamonte, Flavia, De Angelis, Antonella, Urbanek, Konrad, Costanzo, Francesco S., Rota, Marcello, Ellison-Hughes, Georgina M., Torella, Daniele“…Because senescent cells contribute to the outcome of a variety of cardiac diseases, including age-related and unrelated cardiac diseases like diabetic cardiomyopathy and anthracycline cardiotoxicity, therapies that target senescent cell clearance are actively being explored. …”
Publicado 2020
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194937“…The purified fraction named ‘fraction-14’ had shown significant inhibition of yeast alpha glucosidase enzyme activity (IC(50) = 2.4 ± 0.4 μg/mL) when compared to anti-diabetic drug acarbose (IC(50) = 2450 ± 24 μg/mL). …”
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194938por Azab, Sandi M., Zamzam, Abdelrahman, Syed, Muzammil H., Abdin, Rawand, Qadura, Mohammad, Britz-McKibbin, Philip“…Non-targeted metabolite profiling of serum was performed by multisegment injection–capillary electrophoresis–mass spectrometry (MSI–CE–MS) from age and sex-matched, non-diabetic, PAD participants who were recruited and clinically stratified based on the Rutherford classification into CLTI (n = 18) and intermittent claudication (IC, n = 20). …”
Publicado 2020
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194939por Kato, Atsushi, Nakagome, Izumi, Hata, Mizuki, Nash, Robert J., Fleet, George W. J., Natori, Yoshihiro, Yoshimura, Yuichi, Adachi, Isao, Hirono, Shuichi“…Deoxynojirimycin (DNJ) is the archetypal iminosugar, in which the configuration of the hydroxyl groups in the piperidine ring truly mimic those of d-glucopyranose; DNJ and derivatives have beneficial effects as therapeutic agents, such as anti-diabetic and antiviral agents, and pharmacological chaperones for genetic disorders, because they have been shown to inhibit α-glucosidases from various sources. …”
Publicado 2020
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194940“…CASE: A 50-year-old man with no past medical history was admitted with a severe diabetic ketoacidosis following a 4-day history of cough and fever. …”
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