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195121por Giurdanella, Giovanni, Longo, Anna, Distefano, Alfio, Olivieri, Melania, Cristaldi, Martina, Cosentino, Alessia, Agafonova, Aleksandra, Caporarello, Nunzia, Lupo, Gabriella, Anfuso, Carmelina Daniela“…Hyperglycemia-induced impairment of the blood-retinal barrier represents the main pathological event in diabetic retinopathy that is elicited by a reduced cellular response to an accumulation of reactive oxygen species (ROS) and increased inflammation. …”
Publicado 2021
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195122por Lin, Chiao-Yun, Chang, Chen-Bin, Wu, Ren-Chin, Chao, Angel, Lee, Yun-Shien, Tsai, Chi-Neu, Chen, Chih-Hao, Yen, Chih-Feng, Tsai, Chia-Lung“…LSD1 also participated in antioxidant gene regulation with NRF2. In diabetic mice, increasing LSD1and phospho-p62 expression was observed in uterine epithelial cells. …”
Publicado 2021
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195123por Al Turk, Lutfiah, Georgieva, Darina, Alsawadi, Hassan, Wang, Su, Krause, Paul, Alsawadi, Hend, Alshamrani, Abdulrahman Zaid, Saleh, George M., Tang, Hongying Lilian“…The largest public OCT dataset, consisting of 108,312 images and four categories (choroidal neovascularization, diabetic macular edema, drusen, and normal) is used. …”
Publicado 2022
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195124“…Retinal neovascularization (RNV) is a type of serious vision-threating disease, commonly induced by hypoxia of ischemic retinopathy, which happens in various ocular diseases including diabetic retinopathy and retinopathy of prematurity. …”
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195125por Murillo, Katharina, Samigullin, Azat, Humpert, Per M., Fleming, Thomas, Özer, Kübra, Schlotterer, Andrea, Hammes, Hans-Peter, Morcos, Michael“…C. elegans are used to study molecular pathways, linking high glucose levels (HG) to diabetic complications. Persistent exposure of C. elegans to a HG environment induces the mitochondrial formation of reactive oxygen species (ROS) and advanced glycation endproducts (AGEs), leading to neuronal damage and decreased lifespan. …”
Publicado 2022
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195126por Bufalo, Michelle Cristiane, de Almeida, Maíra Estanislau Soares, Jensen, José Ricardo, DeOcesano-Pereira, Carlos, Lichtenstein, Flavio, Picolo, Gisele, Chudzinski-Tavassi, Ana Marisa, Sampaio, Sandra Coccuzzo, Cury, Yara, Zambelli, Vanessa Olzon“…Increased collagen-derived advanced glycation end-products (AGEs) are consistently related to painful diseases, including osteoarthritis, diabetic neuropathy, and neurodegenerative disorders. …”
Publicado 2022
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195127“…We evaluated 15,259 non-diabetic individuals (median age, 45 years; range, 30–85) without previous IHD or ischemic stroke using the Korean National Health Insurance data. …”
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195128por Daudé, Pierre, Ancel, Patricia, Confort Gouny, Sylviane, Jacquier, Alexis, Kober, Frank, Dutour, Anne, Bernard, Monique, Gaborit, Bénédicte, Rapacchi, Stanislas“…The investigation involved 100 subjects—comprising healthy, obese, and diabetic patients—who underwent 3T cardiac cine MRI, optimized U-Net and FCN (noted FCNB) were trained on three consecutive cine frames for segmentation of central frame using dice loss. …”
Publicado 2022
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195129Three-Year Outcomes of Wet Age-Related Macular Degeneration Treatment in Polish Therapeutic Programs“…After the first year, there was a significant difference in the distribution of the best corrected visual acuity according to the Early Treatment Diabetic Retinopathy Study protocol, with more frequent values in the ranges > 35 ≤ 70 for this parameter and > 70 letters in the treatment naïve eye subgroup. …”
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195130por Querfurth, Henry, Marshall, John, Parang, Keykavous, Rioult-Pedotti, Mengia S., Tiwari, Rakesh, Kwon, Bumsup, Reisinger, Steve, Lee, Han-Kyu“…An additional complexity arises from the four-fold risk of Alzheimer’s Disease (AD) in type 2 diabetics, however there is no definitive proof of causation. …”
Publicado 2022
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195131por Zairi, Ihsen, Bejar, Mohamed Amine, Ben Mrad, Imtinen, Mzoughi, Khadija, Kraiem, Sondos“…Results: We studied 40 women and 20 men; mean age was 58.4 years. 33% of the patients were diabetics, 42% dyslipidemics, 15% had coronaropathy. 45% of the patients were on monotherapy, 37% on dual therapy and 18% on a triple antihypertensive therapy. …”
Publicado 2021
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195132“…We present a case of a 62-year-old woman, known diabetic, hypertensive, and hypothyroid patient, who presented with complaints of abdominal distention and obstipation with multiple episodes of vomiting undigested food particles for three days. …”
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195133“…Saxagliptin, an anti-diabetic agent with inhibitory effects against dipeptidyl peptidase 4 (DPP-4), has been recently reported to induce the activation of the AMPK pathway. …”
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195134por Campagnaro, Layon S., Carvalho, Aluizio B., Pina, Paula M., Watanabe, Renato, Canziani, Maria Eugênia F.“…RESULTS: 87 patients (55.6 ± 10.7 years, 62% males, 30% diabetic, eGFR = 39.2 ± 18.1 mL/min/1.73m(2)) were enrolled. …”
Publicado 2022
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195135por Sabo, Angela R., Winfree, Seth, Bledsoe, Sharon B., Phillips, Carrie L., Lingeman, James E., Eadon, Michael T., Williams, James C., El‐Achkar, Tarek M.“…Disease specimens from patients with diabetic kidney disease and focal segmental glomerulosclerosis showed distinctive signatures compared to specimens from healthy controls with normal kidney function. …”
Publicado 2022
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195136“…The meaningful pathways are the AGE-RAGE signaling pathway in diabetic complications, the IL-17 signaling pathway, the TNF signaling pathway, the PI3K-Akt signaling pathway, the MAPK signaling pathway, and apoptosis. …”
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195137“…A pharmacological study showed that the crude extracts and isolated compounds from P. alkekengi had extensive in vitro and in vivo biological activities (e.g., anti-inflammatory, anti-tumor, immunosuppressive, antibacterial, anti-leishmanial, anti-asthmatic, anti-diabetic, anti-oxidative, anti-malarial, anti-Alzheimer’s disease, and vasodilatory). …”
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195138“…A. asphodeloides has been used as an anti-inflammatory, antipyretic, anti-platelet aggregation, anti-depressant, and anti-diabetic agent in traditional Chinese medicine. We examined the antioxidant, anti-acetylcholinesterase (AChE), and anti-α-glucosidase activities of various solvent extracts and the main bioactive compounds from the rhizome of A. asphodeloides. …”
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195139por Sato, Toshihiro, Anan, Go, Hirose, Takuo, Tajima, Ryo, Hoshino, Kento, Miyake, Yuka, Fukunaga, Tsugumi, Kato, Toshiko, Endo, Akari, Ito, Hiroki, Nakayama, Shingo, Hashimoto, Hideaki, Ishiyama, Katsuya, Kimura, Tomoyoshi, Mori, Takefumi“…There were no significant differences in age, operation method, surgeon experience, previous abdominal surgery, medical history of diabetic nephropathy, serum albumin level, and renal function between the two groups. …”
Publicado 2022
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195140por Al Kayal, Tamer, Buscemi, Marianna, Cavallo, Aida, Foffa, Ilenia, Soldani, Giorgio, Losi, Paola“…Plasminogen-loaded fibrin scaffold applied in full-thickness diabetic mouse lesions showed a significantly higher closure rate at 14 days than scaffold used as a reference material. …”
Publicado 2022
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