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195241“…METHODS: HG‐induced ARPE‐19 cells were considered as a cell model of diabetic retinopathy (DR). The viability and apoptosis of ARPE‐19 cells induced by HG treated with either diosgenin or Compound C (CC; dorsomorphin) were detected by Cell Counting Kit‐8 assay and flow cytometric analysis. …”
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195242“…CASE REPORT: A 48-year-old African American male with kidney transplantation secondary to presumed diabetic nephropathy presented 6 years after transplant with lower extremity edema and nephrotic range proteinuria. …”
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195243por Jamal, Muhammad Asghar, Shahazidy, Uzma, Al-Saeed, Fatimah A., Al Syaad, Khalid M., Muneer, Majid, Ahmed, Ikram, Ahmed, Ahmed Ezzat“…Polyols are such a kind of food with desirable qualities, and they play a role in controlling the blood glucose level in diabetic patients. The density (ρ) and sound speed (u) of sugar alcohol in water and in (0.02, 0.04, and 0.06) mol kg(–1)l-arginine solutions at different temperatures (293.15–318.15 K) and atmospheric pressure were measured by using Anton Paar DSA5000M. …”
Publicado 2022
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195244“…Other causes (14%, n = 6) included diabetic papillitis (n = 1), hypertensive retinopathy (n = 1), and central retinal vein occlusion (n = 4). …”
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195245por Lanthier, Nicolas, Lebrun, Valérie, Molendi-Coste, Olivier, van Rooijen, Nico, Leclercq, Isabelle A.“…Hepatokines (liver secreted proteins with possible distant action) are emerging potential players in insulin resistance in type 2 diabetic patients. Here, we explored the effect of a high-fat diet on the expression of fetuin-A, one of those candidate liver proteins, and its relationship with liver macrophage activation. …”
Publicado 2022
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195246por Kang, Eunjeong, Li, Yufei, Kim, Bora, Huh, Ki Young, Han, Miyeun, Ahn, Jung-Hyuck, Sung, Hye Youn, Park, Yong Seek, Lee, Seung Eun, Lee, Sangjun, Park, Sue K., Cho, Joo-Youn, Oh, Kook-Hwan“…We enrolled non-dialytic diabetic nephropathy (DMN, n = 124), hypertensive nephropathy (HTN, n = 118), and polycystic kidney disease (PKD, n = 124) patients from the KNOW-CKD cohort. …”
Publicado 2022
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195247por Hatano, Makoto, Higashijima, Fumiaki, Yoshimoto, Takuya, Ogata, Tadahiko, Ohta, Manami, Kobayashi, Yuka, Wakuta, Makiko, Yanai, Ryoji, Kimura, Kazuhiro“…Administration of intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy is the first-line therapy for diabetic macular oedema (DME). However, some patients show no or insufficient response to repeated anti-VEGF injections. …”
Publicado 2022
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195248por Lingappa, Sivakumar, Shivakumar, Muthugounder Subramanian, Manivasagam, Thamilarasan, Somasundaram, Somasundaram Thirugnanasambandan, Seedevi, Palaniappan“…Epalrestat (EPS) is a brain penetrant aldose reductase inhibitor, an approved drug currently used for the treatment of diabetic neuropathy. At near-plasma concentration, EPS induces glutathione biosynthesis, which in turn reduces oxidative stress in the neuronal cells. …”
Publicado 2021
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195249por Raghavan, Somasundaram, Brishti, Masuma Akter, Collier, Daniel Mohr, Leo, M. Dennis“…Results show that following in vitro hypoxia and reoxygenation, P2Y1R expression is upregulated in both control and diabetic cells. At the same time, endothelial junctional markers, ZO-1 and VE-cadherin, were downregulated, and endothelial permeability increased. siRNA knockdown of P2Y1R and MRS 2500 effectively blocked this response. …”
Publicado 2022
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195250“…Panax ginseng has a wide range of activities including a neuroprotective effect, skin protective effects, enhanced DNA repairing, anti-diabetic activity, and protective effects against vascular inflammation. …”
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195251por Martins-Gomes, Carlos, Steck, Jan, Keller, Judith, Bunzel, Mirko, Nunes, Fernando M., Silva, Amélia M.“…As potential functional foods, T. capitellatus extracts presented neuroprotective and anti-diabetic activity, in addition to time- and dose-dependent anti-proliferative activity against Caco-2 (colorectal adenocarcinoma) and HepG2 (hepatic carcinoma) cells. …”
Publicado 2022
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195252The Matricellular Protein SPARC Decreases in the Lacrimal Gland At Adulthood and During Inflammationpor Feldt, Jessica, Garriz, Angela, Rodriguez Benavente, Maria C., Woodward, Ashley M., Zoukhri, Driss, Argüeso, Pablo“…The effects of cytokines and inflammation in Sparc expression were evaluated in vitro and in the non-obese diabetic (NOD) mouse model of Sjögren's syndrome. RESULTS: The mRNA and protein levels of SPARC were downregulated in lacrimal glands of mature adult mice presenting age-related histological alterations such as increased deposition of lipofuscin and lipids. …”
Publicado 2022
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195253“…Categorically, the greatest amount of Part D expenditures during hospice are for diabetic therapies ($100.2 million), followed by anticoagulants ($97.8 million) and bronchodilators ($57.2 million). …”
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195254por Aspera-Werz, Romina H., Mück, Jonas, Linnemann, Caren, Herbst, Moritz, Ihle, Christoph, Histing, Tina, Nussler, Andreas K., Ehnert, Sabrina“…However, the underlying mechanisms are still unknown. In diabetics, delayed wound healing and infections/sepsis are associated with increased neutrophilic PADI4 expression and formation of neutrophil extracellular traps (NETs). …”
Publicado 2022
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195255“…JAK/STAT plays a key role in regulating uropathogenic Escherichia coli (UPEC) infection in urothelial cells, probably via antimicrobial peptide (AMP) production, in diabetic patients with urinary tract infections. Whether multiple pathways regulate AMPs, especially lipid-carrying protein-2 (LCN2), to achieve a vital effect is unknown. …”
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195256por DuPont, Mariana, Hunsicker, John, Shirley, Simona, Warriner, William, Rowland, Annabelle, Taylor, Reddhyia, DuPont, Michael, Lagatuz, Mark, Yilmaz, Taygan, Foderaro, Andrew, Lahm, Tim, Ventetuolo, Corey E., Grant, Maria B.“…(1) Background: Retinal vascular imaging plays an essential role in diagnosing and managing chronic diseases such as diabetic retinopathy, sickle cell retinopathy, and systemic hypertension. …”
Publicado 2022
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195257por Kabré, Jeanne d’Arc Wendmintiri, Dah-Nouvlessounon, Durand, Hama-Ba, Fatoumata, Agonkoun, Abiola, Guinin, Felix, Sina, Haziz, Kohonou, Arnaud N., Tchogou, Pascal, Senou, Maximien, Savadogo, Aly, Baba-Moussa, Lamine“…The antidiabetic activity of hydroethanolic extracts was evaluated on rats rendered diabetic by streptozotocin, with metformin as a reference molecule. …”
Publicado 2022
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195258“…Ozone therapy was evaluated regarding the treatment of diabetic foot ulcers, digital ulcers, chronic venous leg ulcers, atopic dermatitis, skin burns, onychomycosis, tinea pedis, cutaneous leishmaniasis, balanitis xerotica obliterans and multiple common warts. …”
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195259“…Chemotherapy-induced peripheral neuropathies may serve as a model to study mechanisms of neuropathic pain, since several other common causes of peripheral neuropathy like painful diabetic neuropathy may be due to both neuropathic and non-neuropathic pain mechanisms like ischemia and inflammation. …”
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195260por Wei, Ling, Meng, Jiaqi, Cheng, Kaiwen, He, Wenwen, Qi, Jiao, Lu, Zhong-Lin, Lu, Yi, Zhu, Xiangjia“…The best-corrected visual acuity (BCVA) was evaluated by Early Treatment Diabetic Retinopathy Study charts, and the area under the log CSF (AULCSF), CSF acuity, and CS at six spatial frequencies were evaluated with the qCSF method. …”
Publicado 2022
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