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195381por Bonfiglio, Vincenza, Reibaldi, Michele, Fallico, Matteo, Russo, Andrea, Pizzo, Alessandra, Fichera, Stefano, Rapisarda, Carlo, Macchi, Iacopo, Avitabile, Teresio, Longo, Antonio“…Sustained-release intravitreal 0.7 mg dexamethasone (DEX) implant is approved in Europe for the treatment of macular edema related to diabetic retinopathy, branch retinal vein occlusion, central retinal vein occlusion, and non-infectious uveitis. …”
Publicado 2017
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195382“…BACKGROUND: Osteomyelitis (OM) in diabetics is frequently a polymicrobial infection that rarely involves Pseudomonas (4–5% of cases). …”
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195383por Yun, Jun-Won, Kwon, Euna, Kim, Seung-Hyun, You, Ji-Ran, Kim, Yun-Soon, Park, In Ae, Kim, Hyeon Hoe, Che, Jeong-Hwan, Kang, Byeong-Cheol“…Angelica acutiloba (AA), a Japanese species of Danggui, has been used worldwide as a traditional herbal medicine with several bioactivities including anti-diabetic, anti-allergic, anti-inflammatory, anti-tumor, and anti-obesity. …”
Publicado 2017
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195384por Guo, Xianfeng, Li, Shenghui, Zhang, Jiachun, Wu, Feifan, Li, Xiangchun, Wu, Dan, Zhang, Min, Ou, Zihao, Jie, Zhuye, Yan, Qiulong, Li, Peng, Yi, Jiangfeng, Peng, Yongzheng“…Accurate quantitative analysis of A. muciniphila phylogroups in human subjects further demonstrated its strong correlation with body mass index and anti-diabetic drug usage. Furthermore, we found that, during their mammalian gut evolution history, A. muciniphila acquired extra genes, especially antibiotic resistance genes, from symbiotic microbes via recent lateral gene transfer. …”
Publicado 2017
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195385por Howells, Phillip A, Aldridge, Kerrie A, Parekh, Dhruv, Park, Daniel, Tucker, Olga, Dancer, Rachel C A, Gao, Fang, Perkins, Gavin D, Thickett, David R“…Hospital length of stay was longer for those who took dihydropyridines (median 29 days (IQR 17–42) vs 13 days (IQR 10–18), P=0.0007) or were diabetic (median 25 days (IQR 14–39) vs 13 (IQR 10–19), P=0.023) but not for current smokers (median in never/ex-smokers 13 (IQR 10–23) vs current smokers 15 (IQR 11–20), P=0.73). …”
Publicado 2017
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195386por Jiang, Mingxia, Zhang, Haifen, Zhai, Lijie, Ye, Bianliang, Cheng, Yin, Zhai, Chengkai“…BACKGROUND: Growing evidence indicates that oxidative stress (OS) plays a pivotal role in Diabetic nephropathy (DN). In a previous study we demonstrated that ALA/LA protected HK-2 cells against high glucose-induced cytotoxicity. …”
Publicado 2017
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195387por Tang, Hui, Lei, Chun‐Tao, Ye, Chen, Gao, Pan, Wan, Cheng, Chen, Shan, He, Fang‐Fang, Wang, Yu‐Mei, Su, Hua, Zhang, Chun“…Podocyte injury and depletion are essential events involved in the pathogenesis of diabetic nephropathy (DN). As a terminally differentiated cell, podocyte is restricted in ‘post‐mitosis’ state and unable to regenerate. …”
Publicado 2017
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195388por Gonsoulin, Margaret E, Durazo-Arvizu, Ramon A, Goldstein, Karen M, Cao, Guichan, Zhang, Qiuying, Ramanathan, Dharani, Hynes, Denise M“…We defined these classes as: Healthy (16.24% of the cohort); Ophthalmological Disorders (13.84%); Musculoskeletal Disorders (14.22%); At Risk for Cardiovascular Disease (37.53%); Diabetic with Comorbidities (9.05%); and Multimorbid (9.12%). …”
Publicado 2017
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195389por Winterhalter, Sibylle, Behrens, Uwe Diedrich, Salchow, Daniel, Joussen, Antonia M., Pleyer, Uwe“…At month 2, vitreous haze was reduced from a score of 1.5+ to 0.5+ and 0 and BCVA improved by ≥3 lines, ≥4 lines and ≥2 lines of Early Treatment of Diabetic Retinopathy (ETDRS)-letters, respectively. …”
Publicado 2017
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195390por Clark, Christopher E, Boddy, Kate, Warren, Fiona C, Taylor, Rod S, Aboyans, Victor, Cloutier, Lyne, McManus, Richard J, Shore, Angela C, Campbell, John L“…We will explore variations in risk contribution of IAD across predefined population subgroups (eg, hypertensives, diabetics), establish the lower limit of IAD that is associated with additional cardiovascular risk and assess the impact of different methods of IAD measurement on risk prediction. …”
Publicado 2017
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195391por Yang, Jialiang, Hagen, Jacob, Guntur, Kalyani V., Allette, Kimaada, Schuyler, Sarah, Ranjan, Jyoti, Petralia, Francesca, Gesta, Stephane, Sebra, Robert, Mahajan, Milind, Zhang, Bin, Zhu, Jun, Houten, Sander, Kasarskis, Andrew, Vishnudas, Vivek K., Akmaev, Viatcheslav R., Sarangarajan, Rangaprasad, Narain, Niven R., Schadt, Eric E., Argmann, Carmen A., Tu, Zhidong“…CONCLUSIONS: Our study sheds new light on EV mediated RNA communications between adipocyte and macrophage cells, which may play a significant role in developing insulin resistance in diabetic patients. This work establishes a new method that is applicable to examining genetic material exchanges in many cellular systems and has the potential to be extended to in vivo studies as well. …”
Publicado 2017
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195392por Pompilio, Arianna, Galardi, Giuseppe, Verginelli, Fabio, Muzzi, Maurizio, Di Giulio, Andrea, Di Bonaventura, Giovanni“…We recently described in a diabetic patient a case of recurrent calcaneal ulcer infection caused by a M. odoratimimus strain showing potential for biofilm formation. …”
Publicado 2017
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195393por Brijmohan, Angela S., Batchu, Sri N., Majumder, Syamantak, Alghamdi, Tamadher A., Thieme, Karina, McGaugh, Sarah, Liu, Youan, Advani, Suzanne L., Bowskill, Bridgit B., Kabir, M. Golam, Geldenhuys, Laurette, Siddiqi, Ferhan S., Advani, Andrew“…TFEB mRNA and protein levels were observed to be diminished in the kidneys of humans with diabetic kidney disease, accompanied by accumulation of the protein aggregate adaptor protein p62 in tubule epithelial cells. …”
Publicado 2018
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195394por Meng, Fan-Cheng, Wu, Zheng-Feng, Yin, Zhi-Qi, Lin, Li-Gen, Wang, Ruibing, Zhang, Qing-Wen“…Various investigations have shown that CR and its main alkaloids exhibited many powerful pharmacological effects including anti-inflammatory, anti-cancer, anti-diabetic, neuroprotective, cardioprotective, hypoglycemic, anti-Alzheimer and hepatoprotective activities. …”
Publicado 2018
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195395por Chen, Liyuan, Wang, Lin, Li, Yongjie, Wuang, Liqun, Liu, Yaofang, Pang, Ningbo, Luo, Yulin, He, Jing, Zhang, Liping, Chen, Ni, Li, Rong, Wu, Jianbo“…Conclusion: These results indicate that transplantation of adipose tissue elicits improvements in blood perfusion and beneficial effects on systemic glucose homeostasis and could be a promising therapeutic option for the treatment of diabetic peripheral arterial disease.…”
Publicado 2018
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195396por Jia, Yijie, Zheng, Zongji, Guan, Meiping, Zhang, Qian, Li, Yang, Wang, Ling, Xue, Yaoming“…Extracellular vesicles (EVs), which contain microRNA (miRNA), constitute a novel means of cell communication that may contribute to the inevitable expansion of renal fibrosis during diabetic kidney disease (DKD). Exendin-4 is effective for treating DKD through its action on GLP1R. …”
Publicado 2018
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195397por Li, Yu-Hsuan, Sheu, Wayne Huey-Herng, Lee, Wen-Jane, Wang, Jun -Sing, Fu, Chia-Po, Liang, Kae-Woei, Lee, I-Te“…We evaluated 342 non-diabetic patients with established CAD. ET-1 and renalase levels were measured in all patients after an overnight fast. …”
Publicado 2018
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195398por Castelnuovo, Gianluca, Giusti, Emanuele Maria, Manzoni, Gian Mauro, Saviola, Donatella, Gabrielli, Samantha, Lacerenza, Marco, Pietrabissa, Giada, Cattivelli, Roberto, Spatola, Chiara Anna Maria, Rossi, Alessandro, Varallo, Giorgia, Novelli, Margherita, Villa, Valentina, Luzzati, Francesca, Cottini, Andrea, Lai, Carlo, Volpato, Eleonora, Cavalera, Cesare, Pagnini, Francesco, Tesio, Valentina, Castelli, Lorys, Tavola, Mario, Torta, Riccardo, Arreghini, Marco, Zanini, Loredana, Brunani, Amelia, Seitanidis, Ionathan, Ventura, Giuseppe, Capodaglio, Paolo, D’Aniello, Guido Edoardo, Scarpina, Federica, Brioschi, Andrea, Bigoni, Matteo, Priano, Lorenzo, Mauro, Alessandro, Riva, Giuseppe, Di Lernia, Daniele, Repetto, Claudia, Regalia, Camillo, Molinari, Enrico, Notaro, Paolo, Paolucci, Stefano, Sandrini, Giorgio, Simpson, Susan, Wiederhold, Brenda Kay, Gaudio, Santino, Jackson, Jeffrey B., Tamburin, Stefano, Benedetti, Fabrizio“…Placebo treatments showed weak effects in central neuropathic pain (pain reduction from 0.44 to 0.66 on a 0–10 scale) and moderate effects in postherpetic neuralgia (1.16), in diabetic peripheral neuropathy (1.45), and in pain associated to HIV (1.82). …”
Publicado 2018
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195399por Pinto-Junior, Danilo C., Silva, Karolline S., Michalani, Maria L., Yonamine, Caio Y., Esteves, João V., Fabre, Nelly T., Thieme, Karina, Catanozi, Sérgio, Okamoto, Maristela M., Seraphim, Patricia M., Corrêa-Giannella, Maria L., Passarelli, Marisa, Machado, Ubiratan F.“…The data reveal that AGEs impair glucose homeostasis in non-diabetic states of increased AGEs concentration; an effect that involves activation of endoplasmic reticulum- and inflammatory-stress and repression of Slc2a4/GLUT4 expression.…”
Publicado 2018
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195400por Yau, Kevin, Farragher, Janine F., Kim, S. Joseph, Famure, Olusegun, Jassal, Sarbjit V.“…RESULTS: Of the 82 patients previously studied, 64 (78%) patients participated in the follow-up study (mean age 70.5 ± 4.4 years, 58% male, 55% diabetic). Among those completing functional status measures, 32 (50%) had functional disability at baseline. …”
Publicado 2018
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