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195441“…OBJECTIVE: This review aims at summarizing the current state of knowledge of the pharmacological potential of V and the mechanisms underlying its anti-viral, anti-bacterial, anti-parasitic, anti-fungal, anti-cancer, anti-diabetic, anti-hypercholesterolemic, cardioprotective, and neuroprotective activity as well as the mechanisms of appetite regulation related to the possibility of using this element in the treatment of obesity. …”
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195442por He, Xuemin, Cheng, Rui, Huang, Chao, Takahashi, Yusuke, Yang, Yanhui, Benyajati, Siribhinya, Chen, Yanming, Zhang, Xin A., Ma, Jian-xing“…Here, we observed the upregulation of LRP5 in the renal tubules of both type 1 and type 2 diabetic models and of an obstructive nephropathy model. …”
Publicado 2020
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195443por Liu, Yiming, Ding, Li, Zhang, Bowen, Deng, Ziliang, Han, Yi, Wang, Sihan, Yang, Shu, Fan, Zeng, Zhang, Jing, Yan, Hongmin, Han, Dongmei, He, Lijuan, Yue, Wen, Wang, Hengxiang, Li, Yanhua, Pei, Xuetao“…More importantly, a single dose of TPO remarkably promoted human HSPC homing and subsequent engraftment to the BM of nonobese diabetic/severe combined immunodeficiency mice. We then performed a clinical trial to evaluate the effect of TPO treatment in patients receiving haploidentical BM and mobilized peripheral blood transplantation. …”
Publicado 2020
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195444por John, Kevin John, Turaka, Vijay Prakash, Muruga Bharathy, K., Vignesh Kumar, C., Jayaseelan, L., Visalakshi, J., Nadaraj, Ambily, Mathew, Anoop, Mariam, Faith, Nellimala, Nevin Joseph, Joy, Anisha, Punitha, J.V., Koshy, Maria, Chandy, Gina, Gunasekaran, Karthik, Sudarsanam, Thambu David“…The median total direct cost of admission was INR 84,881.00 ($ 1232.34) CONCLUSION: The VHFR cohort had younger, more diabetic, and fewer hypertensive subjects than most cohorts. …”
Publicado 2020
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195445por Ashwell, Margaret, Gibson, Sigrid, Bellisle, France, Buttriss, Judith, Drewnowski, Adam, Fantino, Marc, Gallagher, Alison M., de Graaf, Kees, Goscinny, Séverine, Hardman, Charlotte A., Laviada-Molina, Hugo, López-García, Rebeca, Magnuson, Berna, Mellor, Duane, Rogers, Peter J., Rowland, Ian, Russell, Wendy, Sievenpiper, John L., la Vecchia, Carlo“…The available evidence suggests no grounds for concerns about adverse effects of LCS on sweet preference, appetite or glucose control; indeed, LCS may improve diabetic control and dietary compliance. Regarding effects on the human gut microbiota, data are limited and do not provide adequate evidence that LCS affect gut health at doses relevant to human use. …”
Publicado 2020
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195446por Kubo, Yuki, Ishikawa, Keijiro, Mori, Kenichiro, Kobayashi, Yoshiyuki, Nakama, Takahito, Arima, Mitsuru, Nakao, Shintaro, Hisatomi, Toshio, Haruta, Masatoshi, Sonoda, Koh-Hei, Yoshida, Shigeo“…Ischemic proliferative retinopathy (IPR), such as proliferative diabetic retinopathy (PDR), retinal vein occlusion and retinopathy of prematurity is a major cause of vision loss. …”
Publicado 2020
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195447por Lv, Jian, Zhang, Kai, Chen, Qing, Chen, Qi, Huang, Wei, Cui, Ling, Li, Min, Li, Jianyin, Chen, Lifei, Shen, Chaolan, Yang, Zhao, Bei, Yixuan, Li, Lanjian, Wu, Xiaohang, Zeng, Siming, Xu, Fan, Lin, Haotian“…The sensitivity of the system was 0.9186, with a specificity of 0.9834. When 349 diabetic patients were included in the training dataset, 501 images were diagnosed correctly and thirty-four were misdiagnosed (including 4 with fungal hyphae and 30 without). …”
Publicado 2020
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195448por Hijazi, Mido M., Buchmann, Sylvia J., Sedghi, Annahita, Illigens, Ben M., Reichmann, Heinz, Schackert, Gabriele, Siepmann, Timo“…Analysis of their integrity can capture early pathology in autonomic neuropathies such as diabetic autonomic neuropathy or peripheral nerve inflammation due to infectious and autoimmune diseases. …”
Publicado 2020
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195449por Louie, Karly S., Erhard, Clement, Wheeler, David C., Stenvinkel, Peter, Fouqueray, Bruno, Floege, Jürgen“…Compared to persistently normocalcemic patients, those with severe hypocalcemia were more often diabetic, overweight, had cardiovascular disease, shorter dialysis vintage, used a catheter dialysis access, had fewer active vitamin-D sterols, and exhibited higher CRP and iPTH and lower calcium levels. …”
Publicado 2019
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195450por Qi, Jingjing, Tang, Xiaojun, Li, Wenchao, Chen, Weiwei, Yao, Genhong, Sun, Lingyun“…METHODS: The number and immune-suppressive activity of myeloid-derived suppressor cells (MDSCs), polymorphonuclear MDSCs (PMN-MDSCs), and monocytic MDSCs (M-MDSCs) were determined in non-obese diabetic (NOD) mice with sialadenitis and in NOD mice with human umbilical cord-derived MSC (UC-MSC) transplantation. …”
Publicado 2020
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195451por El-Kannishy, Ghada, Elsawaf, Reham, Tarek Elsaber, Rana, Magdi Elbanasawi, Hebatalla, Magdi Elbahnasawi, Menatalla, Latif, Soha Ali Abdel, Megahed, Abir, Sayed-Ahmed, Nagy“…Absence of clear recommendations to guide fasting in Ramadan in HD patients as in diabetic patients makes permission or prohibition of such practice unjustified.…”
Publicado 2019
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195452“…RESULTS: Intravitreal injections were successfully administered to 132 patients with diabetic retinopathy, age-related macular degeneration and retinal vein occlusion. …”
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195453“…Subgroup analyses revealed a suggestive association between the GC genotype of IL-6-174 G/C with proliferative diabetic retinopathy (PDR). Further, the level of intraocular IL-6 among ocular disease patients in general was found to be higher than the control group [standardized mean difference (SMD) = 1.41, 95% confidence interval (CI) 1.24–1.58, P < 0.00001]. …”
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195454por Mamtora, Dhruv, Saseedharan, Sanjith, Rampal, Ritika, Joshi, Prashant, Bhalekar, Pallavi, Ahdal, Jaishid, Jain, Rishi“…Levonadifloxacin and its oral prodrug alalevonadifloxacin, a novel benzoquinolizine antibiotic, have recently been approved for acute bacterial skin and skin structure infections including diabetic foot infections and concurrent bacteremia in India. …”
Publicado 2020
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195455“…The preoperative corrected distance visual acuity (CDVA) was ≥1.0/≥1.0 LogMAR units on Snellen chart and <20/<20 points on Early Treatment Diabetic Retinopathy Study (ETDRS) chart. Patients were not on active treatment for wet AMD as the treatment was expected to have no effect or benefit. …”
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195456por Fujii, Ai, Sunatani, Yumi, Furuichi, Kengo, Fujimoto, Keiji, Adachi, Hiroki, Iwabuchi, Kuniyoshi, Yokoyama, Hitoshi“…In renal biopsy samples, immunohistochemical analyses revealed that COL6 and phosphorylated histone H2AX (γ-H2AX), a DNA damage marker, were detected mainly in diabetic nodular glomerulosclerosis, in which the γ-H2AX-positive area was identified as the independent factor significantly associated with the COL6-positive area (β: 0.539, t = 2.668). …”
Publicado 2020
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195457por Wang, Jingyu, Yue, Xiaodan, Meng, Cheng, Wang, Ziyan, Jin, Xiaofang, Cui, Xiao, Yang, Juhong, Shan, Chunyan, Gao, Zhongai, Yang, Yanhui, Li, Jing, Chang, Bai, Chang, Baocheng“…In the present study, we explored the dose-effect relationship and the pivotal role of mitophagy in acute hyperglycemia induced tubular injuries. METHODS: Forty non-diabetic SD rats were randomly divided and treated with different concentrations of hyperglycemia respectively during the 6-h clamp experiment. …”
Publicado 2020
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195458“…Best-corrected visual acuity (BCVA) was 43 Early Treatment Diabetic Retinopathy Study (ETDRS) letters in the left eye. …”
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195459por Pillay, Ethan, Naidoo, Thiroshnee, Asmal, Khadija, Maliwa, Lilitha, Mchunua, Sinenhlanhla, van Staden, Diane Beverly, Rampersad, Nishanee“…The Optovue iVue100 optical coherence tomographer was used to measure retinal thickness in the nine Early Treatment Diabetic Retinopathy Study (ETDRS) sectors including the central foveal, parafoveal and perifoveal regions. …”
Publicado 2021
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195460por Russo, Michele, Della Sala, Angela, Tocchetti, Carlo Gabriele, Porporato, Paolo Ettore, Ghigo, Alessandra“…Moreover, increasing evidence links DOXO cardiotoxicity to imbalanced insulin signaling and to cardiac insulin resistance. Although anti-diabetic drugs, such as empagliflozin and metformin, have shown interesting cardioprotective effects in vitro and in vivo in different models of heart failure, their mechanism of action is unclear, and their use for the treatment of DOXO cardiotoxicity is still unexplored. …”
Publicado 2021
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