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195741“…Nineteen pre-bariatric surgery CSO, non-diabetic women were recruited (age=32.6±7.7 SD; BMI=46.5±9.0 kg/m(2)). …”
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195742por Hajnal, Andras, Zharikov, Alevtina, Polston, James E., Fields, Maxine R., Tomasko, Jonathan, Rogers, Ann M., Volkow, Nora D., Thanos, Panayotis K.“…High fat (60%kcal from fat) diet-induced obese, non-diabetic male Sprague Dawley rats underwent RYGB (n = 9) or sham operation (Sham, n = 9) and were tested 4 months after surgery on a progressive ratio-10 (PR10) schedule of reinforcement operant task for 2, 4, and 8% ethanol. …”
Publicado 2012
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195743por Yin, Xiao, Sun, Qiang, Zhang, Xiuping, Lu, Yong, Sun, Chao, Cui, Ying, Wang, Shaolian“…The present study aims to examine the association between serum vitamin D concentrations and cardiometabolic risk factors in the young and middle-aged, urban Chinese population METHODS: The cross-sectional relationships between serum 25-hydroxyvitamin D [25(OH)D] concentrations and indices of adiposity and cardiometabolic risk factors (e.g., body mass index, waist circumference, fasting plasma glucose, etc.) were evaluated in 601 non-diabetic adults. RESULT: Vitamin D deficiency or insufficiency was present in 66% of the tested population, and serum 25(OH)D levels were lower in patients who were overweight/obese or suffered metabolic syndrome when compared to individuals of healthy weight without metabolic syndrome (24.08 ± 8.08 vs 31.70 ± 11.77 ng/ml, 21.52 ± 6.9 vs 31.74 ± 10.21 ng/ml respectively). 25(OH)D was inversely associated with waist circumference, fasting glucose, fasting insulin, triglycerides and LDL-cholesterol, and it was positively associated with HDL-cholesterol in a multivariable-adjusted regression model. …”
Publicado 2012
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195744por Vargas-Camaño, Eugenia, Castrejon-Vázquez, Isabel, Plazola-Hernández, Sara I., Moguel-Ancheita, Silvia“…METHODS: Case 1: 60 year-old non-diabetic woman with bilateral glaucoma in treatment, recurrent media otitis and euthyroidism, acute onset of painless diplopia, and lid ptosis in the left eye. …”
Publicado 2012
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195745“…The peak systolic velocity (PSV), end diastolic velocity (EDV) and resistance index were measured excluding hypertensive, diabetic patients and patients with cardiovascular disease. …”
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195746por Lipsky, Benjamin A, Moran, Gregory J, Napolitano, Lena M, Vo, Lien, Nicholson, Susan, Kim, Myoung“…METHODS: From June 2008 to December 2009 we enrolled a pre-specified number of adults treated in 56 U.S. hospitals with intravenous antibiotic(s) for any of the following cSSTIs: diabetic foot infection (DFI); surgical site infection (SSI); deep soft tissue abscess (DSTA); or, cellulitis. …”
Publicado 2012
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195747por Liu, Guan-Xian, Li, You-Qi, Huang, Xiao R., Wei, Lihua, Chen, Hai-Yong, Shi, Yong-Jun, Heuchel, Rainer L., Lan, Hui Y.“…Smad7 is an inhibitory Smad and plays a protective role in obstructive and diabetic kidney disease. However, the role and mechanisms of Smad7 in hypertensive nephropathy remains unexplored. …”
Publicado 2013
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195748“…Elevated levels of glycated low density lipoprotein (glyLDL) are frequently detected in diabetic patients. Previous studies demonstrated that glyLDL increased the production of reactive oxygen species (ROS), activated NADPH oxidase (NOX) and suppressed mitochondrial electron transport chain (mETC) enzyme activities in vascular endothelial cells (EC). …”
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195749“…The conspicuous pattern of ANS dysfunction raises the possibility that obesity may give rise to dysfunction of the peripheral autonomic nerves resembling that observed in normal-weight diabetic children and adolescents.…”
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195750por Itariu, Bianca K., Zeyda, Maximilian, Leitner, Lukas, Marculescu, Rodrig, Stulnig, Thomas M.“…Fifty-four severely obese (BMI≥40 kg/m2) non-diabetic patients were treated for eight weeks with either 3.36 g/d EPA and DHA or the same amount of butter fat as control. …”
Publicado 2013
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195751por Sekiyama, Hiroshi, Nagoshi, Tomohisa, Komukai, Kimiaki, Matsushima, Masato, Katoh, Daisuke, Ogawa, Kazuo, Minai, Kosuke, Ogawa, Takayuki, Yoshimura, Michihiro“…The degree of the potassium dip was tightly correlated with glucose level, which overwhelmed the diabetic condition, and it also indicates the disease severity. …”
Publicado 2013
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195752“…Bevacizumab, a drug widely used in the treatment of neovascular age-related macular degeneration, choroidal neovascularization, and proliferative diabetic retinopathy, neutralizes all isoforms of VEGF. …”
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195753por ZUNINO, SUSAN J., STORMS, DAVID H., NEWMAN, JOHN W., PEDERSEN, THERESA L., KEEN, CARL L., DUCORE, JONATHAN M.“…In this study, the efficacy of orally and parenter-ally administered curcumin was evaluated in non-obese diabetic/severe combined immunodeficient (NOD/SCID) mice (NOD.CB17-Prkdc(scid)/J mice) engrafted with the human t(4;11) acute lymphoblastic leukemia line, SEM. …”
Publicado 2012
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195754por Huang, Shaoguang, Liu, Fei, Niu, Qin, Li, Yi, Liu, Chang, Zhang, Lele, Ni, Danni, Pu, Xiaoyun“…In this study, we found that GLIPR-2 expression is elevated in the kidney tissue samples of patients with diabetic nephropathy (DN). Human proximal renal tubular epithelial cells (HK-2 cells) were transfected with pcDNA3.0-GLIPR-2 and selected with G418. …”
Publicado 2013
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195755por Hall, Gillian C, Morant, Steve V, Carroll, Dawn, Gabriel, Zahava L, McQuay, Henry J“…METHODS: Patients with a first diagnosis of post-herpetic neuralgia (PHN), painful diabetic neuropathy (PDN) or phantom limb pain (PLP) were identified from the General Practice Research Database (2006 – 2010) and incidence rates were calculated. …”
Publicado 2013
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195756por Rognant, Nicolas, Alamartine, Eric, Aldigier, Jean Claude, Combe, Christian, Vendrely, Benoit, Deteix, Patrice, Cluzel, Pascal, Juillard, Laurent, Vrtovsnik, François, Maurice, Christelle, Fave, Sophie, Laville, Maurice“…METHODS: This observational matched cohort study included 40 patients with CKD stage 4–5 in the network group as compared with a control group of 120 patients matched for age, sex and diabetic status. Main outcome was a composite endpoint of death from cardiovascular cause and cardiovascular events during the first year after dialysis initiation. …”
Publicado 2013
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195757“…CONCLUSION: The results suggest that one of the mechanisms for the anti-diabetic effect of Pe, Cl and Tc may be through an insulin sensitizing effect (stimulation of glucose uptake into adipocytes). …”
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195758por Chen, Xianguang, Mori, Takefumi, Guo, Qi, Hu, Chunyan, Ohsaki, Yusuke, Yoneki, Yoshimi, Zhu, Wanjun, Jiang, Yue, Endo, Satoshi, Nakayama, Keisuke, Ogawa, Susumu, Nakayama, Masaaki, Miyata, Toshio, Ito, Sadayoshi“…One major precursor of carbonyl stress, methylglyoxal (MG), is elevated in the plasma of chronic kidney disease (CKD) patients, and this precursor contributes to the progression of vascular injury, hypertension and renal injury in diabetic nephropathy patients. This molecule induces salt-sensitive hypertension via a reactive oxygen species-mediated pathway. …”
Publicado 2013
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195759por Goh, Tony Kwang-Poh, Zhang, Zhi-Yong, Chen, Allen Kuan-Liang, Reuveny, Shaul, Choolani, Mahesh, Chan, Jerry Kok Yen, Oh, Steve Kah-Weng“…Surprisingly, when MC-hfMSCs and MNL-hfMSCs were seeded on 3D macroporous scaffold culture or subcutaneously implanted into nonobese diabetic/severe combined immunodeficient mice, MC-hfMSCs deposited 63.5% (p<0.05) more calcium and formed 47.2% (p<0.05) more bone volume, respectively. …”
Publicado 2013
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195760por Gilardini, Luisa, Lombardi, Carolina, Redaelli, Gabriella, Vallone, Luciana, Faini, Andrea, Mattaliano, Paola, Parati, Gianfranco, Invitti, Cecilia“…The study explored 1) whether OSA is associated with impaired glucose homeostasis in obese non diabetic premenopausal and menopausal women and 2) the effects of a 3- month lifestyle intervention on glucose homeostasis in OSA women. …”
Publicado 2013
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