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196161“…RESULTS: Of our 31 patients with a diagnosis of blindness or toxic maculopathy, 11 had documented blindness, in all cases attributed to a cause other than HCQ-related ocular toxicity: stroke (27%), pre-existing macular disease (18%), diabetic retinopathy (18%), hypertensive retinopathy (9%) and cataracts (9%). …”
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196162por Tótoli, Cláudia, Carvalho, Aluizio Barbosa, Ammirati, Adriano Luiz, Draibe, Sergio Antônio, Canziani, Maria Eugênia F.“…Compared to non progressor, the progressor patients were younger [72 (69–78) vs. 76 (69–80) years; p = 0.02]; had higher proportion of diabetic nephropathy, higher serum phosphorus [3.8 (3.3–4.1) vs. 3.5 (3.9–4.1) mg/dL; p = 0.04] and proteinuria [0.10 (0–0.9 vs. 0 (0–0.3)] g/L; p = 0.007)] at the admission. …”
Publicado 2019
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196163por Zhang, Jichen, Zhao, Xuemei, Zhu, Hongling, Wang, Jingnan, Ma, Junhua, Gu, Mingjun“…BACKGROUND: Diabetic nephropathy (DN) is a disease characterized by oxidative stress and apoptosis of renal tubular epithelial cells driven by hyperglycemia. …”
Publicado 2019
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196164“…As a major cause of blindness, diabetic retinopathy (DR) is often found in the developed countries. …”
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196165“…METHODS: Among 10,059 men, aged 40–65, tenured civil servants and municipal employees in Israel, 8822 participants who were examined in 1963, 1965 and 1968 had assessment of diabetic and coronary morbidity status and SUA levels. …”
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196166por Rochfort, Keith D., Carroll, Lara S., Barabas, Peter, Curtis, Timothy M., Ambati, Balamurali K., Barron, Niall, Cummins, Philip M.“…PURPOSE: Current treatments for diabetic retinopathy (DR) have considerable limitations, underpinning the need for new therapeutic options. …”
Publicado 2019
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196167“…METHODS: Eighty-four consecutive type 2 diabetic patients with unstable angina (UA) were included from January 2018 to June 2018 to calculate calcification scores using computerized tomographic angiography (CTA), and the patients were divided into 2 groups: high calcification score group (HCS group) and low calcification score group (LCS group). …”
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196168por Han, Xiaotong, Scheetz, Jane, Keel, Stuart, Liao, Chimei, Liu, Chi, Jiang, Yu, Müller, Andreas, Meng, Wei, He, Mingguang“…METHODS: Three study populations (elderly Chinese, adolescent Chinese, and Australian groups) underwent distance and near VA testing using standard Early Treatment Diabetic Retinopathy Study (ETDRS) charts and the V@home device; all VA tests used tumbling E optotypes. …”
Publicado 2019
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196169por Zhao, Jiangpei, Liu, Lerong, Zhang, Lingxiao, Lv, Jing, Guo, Xueli, Li, Xia, Zhao, Tongfeng“…To the best of our knowledge, the present study is the first to report such results and provide evidence that SF protects HT22 cells from high glucose-induced toxicity by activating the Nrf2/HO-1 pathway and inhibiting the expression of NF-κB, which may be of therapeutic value in diabetic encephalopathy.…”
Publicado 2019
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196170por Deng, Haoyu, Liu, Huitao, de Silva, Tanya, Xue, YuanChao, Mohamud, Yasir, Ng, Chen Seng, Qu, Junyan, Zhang, Jingchun, Jia, William W.G., Lockwood, William W., Luo, Honglin“…Our results revealed that intratumoral injection of CVB3 results in a marked tumor regression of KRAS(mut) lung adenocarcinoma in both non-obese diabetic (NOD) severe combined immunodeficiency (SCID) gamma (NSG) and NOD-SCID xenograft models. …”
Publicado 2019
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196171por Gao, Chenlin, Chen, Jiao, Fan, Fang, Long, Yang, Tang, Shi, Jiang, Chunxia, Wang, Jiying, Xu, Youhua, Xu, Yong“…BACKGROUND: Hyperglycemia plays a vital role in diabetic nephropathy (DN); autophagy and its potential upregulator receptor-interacting protein kinase 2 (RIPK2) are associated with ROS, which play a potential role in regulating NLRP3, and may be involved in inflammation in DN. …”
Publicado 2019
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196172“…Context: The substantial increase in the number of diabetics has encouraged the search for new pharmacological strategies to face this problem. …”
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196173“…In addition, OCTA can depict neovascularization of the iris secondary to proliferative diabetic retinopathy.…”
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196174por Akbilgic, Oguz, Obi, Yoshitsugu, Potukuchi, Praveen K., Karabayir, Ibrahim, Nguyen, Danh V., Soohoo, Melissa, Streja, Elani, Molnar, Miklos Z., Rhee, Connie M., Kalantar-Zadeh, Kamyar, Kovesdy, Csaba P.“…RESULTS: The mean (±SD) age of our cohort was 68.7 ± 11.2 years, 98.1% of patients were men, 29.4% were African American, and 71.4% were diabetic. The final random forest model provided C-statistics (95% confidence intervals) of 0.7185 (0.6994–0.7377), 0.7446 (0.7346–0.7546), 0.7504 (0.7425–0.7583), and 0.7488 (0.7421–0.7554) for predicting risk of death within the 4 different time windows. …”
Publicado 2019
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196175por Lambie, Mark, Teece, Lucy, Johnson, David W, Petrie, Michaela, Mactier, Robert, Solis-Trapala, Ivonne, Belcher, John, Bekker, Hilary L, Wilkie, Martin, Tupling, Ken, Phillips-Darby, Louise, Davies, Simon J“…Age, time on PD, primary renal disease, gender, data set and diabetic status were evaluated as predictors at the start of PD, then at 3 and 5 years after starting PD using flexible parametric competing risks models. …”
Publicado 2019
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196176por Alikhani, Ahmad, Morin, Helene, Matte, Stephanie, Alikhani, Pouriya, Tremblay, Cécile, Durand, Madeleine“…(p = 0.003, p = 0.002, respectively) Patients classified as lipodystrophic were more likely to be diabetic (50 vs. 28%, p = 0.07) and to have dyslipidemia (47 vs. 19%, p = 0.01). …”
Publicado 2019
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196177“…Visual improvement at 12 months was +5.2 (11.8) and +1.2 (12.7) letters Early Treatment Diabetic Retinopathy Study (ETDRS) in TE‐ and PRN‐cohorts, respectively (p = 0.002). …”
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196178por Mandal, Subhankar P., Garg, Aakriti, Prabitha, P., Wadhwani, Ashish D., Adhikary, Laxmi, Kumar, B. R. Prashantha“…Specifically, CPD03, 07, 08, 18, 19, 21 and 24 are the candidate glitazones exhibited significant glucose uptake activity. 3D-QSAR model revealed the scope for possible further modifications as part of optimisation to find potent anti-diabetic agents. [Image: see text]…”
Publicado 2018
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196179por Allegra, Alexis B., Gharibans, Armen A., Schamberg, Gabriel E., Kunkel, David C., Coleman, Todd P.“…Our method finds statistically significant wave propagation in all stomach regions for both subjects, anterograde activity throughout for the subject with diabetic gastroparesis, and retrograde activity in some regions for the subject with idiopathic gastroparesis. …”
Publicado 2019
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196180por Ananian, Charles E., Davis, R. Daniel, Johnson, Eric L., Regulski, Matthew J., Reyzelman, Alexander M., Saunders, Molly C., Danilkovitch, Alla“…Results: Seventy-eight patients with 98 wounds (41 diabetic foot ulcers [DFUs], 19 venous leg ulcers [VLUs], 10 surgical, and 28 others) with an average size of 13.3 cm(2) and 8.7 months duration were treated. …”
Publicado 2019
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