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196521“…RESULTS: This study ultimately included 29,337 participants aged >20 years, of whom 1022 self-reported a history of stroke, and after adjusting for all confounders, each unit increase in corrected VAI was associated with a 12% increase in the prevalence of stroke (OR= 1.12, 95% CI: 1.01, 1.24) along with an earlier age at stroke 1.64 years (β= -1.64, 95% CI: -2.84, -0.45), stratified analysis showed that the prevalence of stroke was 20% higher in the female group (OR= 1.20, 95% CI: 1.04, 1.39), black group (OR= 1.22, 95% CI: 1.01, 1.48), age ≤60 years group (OR= 1.25, 95% CI: 1.05, 1.48), hypertensive group (OR=1.15, 95% CI:1.01, 1.31), and diabetic group (OR=1.23, 95% CI:1.02, 1.48) VAI increase was positively correlated with stroke prevalence increase. …”
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196522por Low, Stewart A., Nielsen, Jeffery J., Coakley, Cheyanne M., Thomas, Mini, Mbachu, Ephraim U., Chen, Christopher L., Jones-Hall, Yava, Tremblay, Madeleine I., Hicks, Jonathan R., Low, Philip S.“…Additionally, since similar results are obtained upon treatment of osteoporotic and diabetic fractures in mice, and pain resolution is simultaneously accelerated by this approach, we conclude that this fracture-targeted anabolic peptide displays significant potential to revolutionize the treatment of bone fractures.…”
Publicado 2022
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196523por Tian, Zenghui, Hao, Yanke, Wang, Mingliang, Li, Yingying, Cui, Kaiying, Hou, Pengfei, Wang, Xiaoying, Lv, Dengwan, Shi, Jie“…Important roles of the following pathway were identified: cancer, lipid, and atherosclerosis; AGE-RAGE signaling pathway in diabetic complications; chemical carcinogenesis – receptor activation; PI3K -Akt signaling pathway; platinum drug resistance; cAMP signaling pathway; transcriptional mis regulation in cancer; serotonergic synapse; and malaria. …”
Publicado 2023
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196524“…Among all sub-indicators considered, the greater proportion of females and smaller proportion of rural residents in Black counties were the two largest contributors to the COVID-19 mortality gap between Black and non-Black counties. Proportions of diabetic residents, uninsured residents, and the degree of income inequality also significantly contributed to the gap in COVID-19 mortality. …”
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196525por Al Mahri, Saeed, Okla, Meshail, Rashid, Mamoon, Malik, Shuja Shafi, Iqbal, Jahangir, Al Ibrahim, Maria, Dairi, Ghida, Mahmood, Amer, Muthurangan, Manikandan, Yaqinuddin, Ahmed, Mohammad, Sameer“…In addition, the expression of GPCRs in subcutaneous adipose tissues from lean, obese, and diabetic human subjects and in adipocytes isolated from regular chow and high-fat fed mice were evaluated by re-analyzing RNA-sequencing data. …”
Publicado 2023
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196526“…Therefore, they explain the mechanical origin of bone brittleness as commonly observed in elderly and diabetic populations. Our findings contribute to a better understanding of the mechanisms underlying impaired tissue behaviour due to elevated AGEs content and could enable targeted measures regarding the reduction of specific collagen cross-linking levels.…”
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196527por Aitekenov, Sultan, Sultangaziyev, Alisher, Boranova, Aigerim, Dyussupova, Aigerim, Ilyas, Aisha, Gaipov, Abduzhappar, Bukasov, Rostislav“…Excessive protein excretion in human urine is an early and sensitive marker of diabetic nephropathy and primary and secondary renal disease. …”
Publicado 2023
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196528“…According to OCT reports of senior ophthalmologists, there were 300 images with diabetic (DME), 303 images with age-related macular degeneration (AMD), 304 images with retinal-vein occlusion (RVO), and 306 images with central serous chorioretinopathy (CSC). …”
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196529por Brandl, Caroline, Zimmermann, Martina E., Herold, Janina M., Helbig, Horst, Stark, Klaus J., Heid, Iris M.“…Visual acuity (VA) was assessed via Early Treatment Diabetic Retinopathy Study (ETDRS) charts. After a 30-second bleaching of the macular region via direct ophthalmoscope, PRT was measured as the seconds to regain VA. …”
Publicado 2023
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196530por Mun-Wei, Lam, Aiman-Mardhiyyah, Mohd Yazid, Hayati, Abdul Aziz, Ikram, Ilias Mohamad, Tai, Evelyn Li Min, Shatriah, Ismail“…The mean macular thickness was measured using Stratus optical coherence tomography according to nine areas of the Early Treatment Diabetic Retinopathy Study map. RESULTS: The mean foveal thickness was 238.15 ± 22.98 μm for children with nephrotic syndrome and 237.01 ± 22.60 μm for the control group. …”
Publicado 2023
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196531por Loewinger, Anne-Sophie, Pfau, Maximilian, Herrmann, Philipp, Holz, Frank G., Pfau, Kristina“…Spectral-domain optical coherence tomography (SD-OCT) images were analyzed for thicknesses of the choroid and outer retinal microstructure and correlated with choriocapillaris FDs in the respective Early Treatment Diabetic Retinopathy Study subfield. RESULTS: The multivariable mixed model analysis for choriocapillaris FDs revealed significantly higher FDs associated with the group (PXE patients vs. controls +13.6; 95% confidence interval [CI] 9.87–17.3; P < 0.001), with increasing age (+0.22% per year; 95% CI 0.12–0.33; P < 0.001), and with retinal location (significantly higher FDs in nasal compared to temporal subfields). …”
Publicado 2023
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196532por Peterson, John S., Plana, Deborah, Bitterman, Danielle S., Johnson, Skyler Bryce, Aerts, Hugo J. W. L., Kann, Benjamin Harris“…Eighteen exclusion criteria categories were significantly associated with accrual failure, including renal, pulmonary, and diabetic, among others (Bonferroni‐corrected p < 0.001). …”
Publicado 2022
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196533“…Multivariable analysis revealed age ≥ 65 years (AOR = 2.62, 95% CI = 1.33–5.14), having shortness of breath (AOR = 1.87, 95% CI = 1.02–3.44), fatigue (AOR 1.78, 95% CI = 1.09–2.90), altered consciousness (AOR 3.02, 95% CI = 1.40, 6.49), diabetic Mellitus (AOR = 2.79, 95% CI = 1.16–6.73), chronic cerebrovascular disease (AOR = 2.1, 95% CI = 1.23, 3.88) were found to be predictors of death. …”
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196534por Vasiliu, Octavian“…The quality of primary and secondary reports was assessed using the criteria identified by the Academy of Nutrition and Diabetics. Forty-three sources, mostly of moderate and high quality, were reviewed in detail, and data regarding the efficacy and tolerability of psychobiotics was assessed. …”
Publicado 2023
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196535por Mehrpour, Omid, Saeedi, Farhad, Nakhaee, Samaneh, Tavakkoli Khomeini, Farbod, Hadianfar, Ali, Amirabadizadeh, Alireza, Hoyte, Christopher“…BACKGROUND: Biguanides and sulfonylurea are two classes of anti-diabetic medications that have commonly been prescribed all around the world. …”
Publicado 2023
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196536por Topaz, Leah Shafran, Frid, Alex, Granovsky, Yelena, Zubidat, Rabab, Crystal, Shoshana, Buxbaum, Chen, Bosak, Noam, Hadad, Rafi, Domany, Erel, Alon, Tayir, Meir Yalon, Lian, Shor, Merav, Khamaisi, Mogher, Hochberg, Irit, Yarovinsky, Nataliya, Volkovich, Zeev, Bennett, David L., Yarnitsky, David“…Based solely on resting state EEG signals, a data‐driven, predictive and explanatory approach is presented to discriminate painful from non‐painful diabetic polyneuropathy (DPN) patients. METHODS: Three minutes long, 64 electrode resting‐state recordings were obtained from 180 DPN patients. …”
Publicado 2022
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196537por Negm, Essamedin M., Mohamed, Mohamed Sorour, Rabie, Rehab A., Fouad, Walaa S., Beniamen, Ahmed, Mosallem, Ahmed, Tawfik, Ahmed E., Salama, Hussein M.“…Candida was the most frequently isolated fungus in 61 (24.1%) of 253 critically ill COVID-19 patients, followed by molds, which included Aspergillus 11 (4.3%) and mucormycosis in five patients (1.97%), and six patients (2.4%) diagnosed with other rare fungi. Poor diabetic control, prolonged or high-dose steroids, and multiple comorbidities were all possible risk factors for fungal coinfection [OR (95% CI) = 10.21 (3.43–30.39), 14.1 (5.67–35.10), 14.57 (5.83–33.78), and 4.57 (1.83–14.88), respectively]. …”
Publicado 2023
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196538“…The expression of PP1α and PP1γ was determined in insulin resistant N2a, SH-SY5Y cells and in high-fat-diet-fed-diabetic mice whole-brain-lysates. PP1α and PP1γ were silenced by siRNA in N2a and SH-SY5Y cells and effect was tested on AKT isoforms, AS160 and GSK3 isoforms using western immunoblot, GLUT4 translocation by confocal microscopy and glucose uptake by fluorescence-based assay. …”
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196539por Treiber, Guillaume, Gonthier, Marie-Paule, Guilleux, Alice, Medjane, Samir, Bonfanti, Oriane, Cogne, Muriel, Meilhac, Olivier, Nobecourt, Estelle“…The populations were closely matched for age, sex, and diabetic status. RESULTS: Metabolic outcomes were similar between the two populations. …”
Publicado 2023
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196540por Yu, Chao, Zou, Jie, Ge, Qian-Min, Liao, Xu-Lin, Pan, Yi-Cong, Wu, Jie-Li, Su, Ting, Zhang, Li-Juan, Liang, Rong-Bin, Shao, Yi“…OCTA image segmentation for analysis was conducted using the central wheel division method (C1–C6), hemisphere segmentation method (SR, SL, IL, and IR), and the early treatment of diabetic retinopathy study method (ETDRS) (R, S, L, and I). …”
Publicado 2023
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