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196541“…The naturally occurring phytosterol; β-sitosterol has antiobesogenic and anti-diabetic properties. The purpose of this study was to explore the role of β-sitosterol in preventing hepatic steatosis induced by a high-fat diet (HFD) in rats. …”
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196542por Soares, Ricardo Machado, Braga, Joana Figueiredo, da Silva Fernandes, Joana, Ferreira, Catarina Cunha, Ribeiro, Lígia, Alves, Hélio, Meira, Dália“…The layer thickness was measured in each sector according to the Early Treatment Diabetic Retinopathy Study and the 6-sector Garway-Heath-based grids. …”
Publicado 2023
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196543“…BACKGROUND: Metformin as a first-line clinical anti-diabetic agent prolongs the lifespan of model animals and promotes cell proliferation. …”
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196544por Zhang, Tongshuai, Wu, Jinrong, Yao, Xinmin, Zhang, Yao, Wang, Yue, Han, Yang, Wu, Yun, Xu, Zhenyu, Lan, Jing, Han, Siyu, Zou, Haifeng, Sun, Qixu, Wang, Dandan, Zhang, Jingyu, Wang, Guangyou“…Epalrestat is the only AR inhibitor with proven safety and efficacy, which is used in the clinical treatment of diabetic neuropathy. However, the molecular mechanisms underlying the neuroprotection of epalrestat remain unknown in the ischemic brain. …”
Publicado 2023
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196545por Montazeri, Marzieh, Zarkesh, Maryam, Zadeh-Vakili, Azita, Khalili, Davood, Movahedi, Monireh, Khalaj, Alireza“…We examined the association of PI3K and Akt expression in visceral (VAT) and subcutaneous adipose tissue (SAT) with daily physical activity (PA) in non-diabetic obese and non-obese adults. In this cross-sectional study, we included 105 obese (BMI ≥ 30 kg/m(2)) and 71 non-obese (BMI < 30 kg/m(2)) subjects (aged/ ≥ 18 years). …”
Publicado 2023
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196546“…Bony reactions in the area of coalitions, arthrodesis, osteosynthesis, occult fractures, prostheses and diabetic foot cannot be detected with comparable accuracy using any other imaging method, so that therapy concepts in unclear cases, based only on standard imaging are changed in up to 2/3 of cases by SPECT/CT information. …”
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196547por Alharthi, Sawsan A. S., Alaisayi, Khulud Hassan A., Alalawi, Lina Yousef S., Alamri, Raniya Omar S., Abu-Elfotuh, Karema, Alenazi, Tahani S., Amirthalingam, Palanisamy, Albariqi, Hassan A. H., Mohammed, Asmaa A., Alsubayti, Norah, Hamdan, Ahmed M. E., Kozman, Magy R.“…Furthermore, females, graduates, diabetics were significantly high irrespective of their subgroup. …”
Publicado 2023
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196548por Li, ChangYan, Zhong, HuaChen, Ma, JingYuan, Liang, Zhang, Zhang, Le, Liu, Tao, Fan, WenXing“…BACKGROUND: Diabetic nephropathy (DN) is a chronic condition resulting from microangiopathy in a high-glucose environment. …”
Publicado 2023
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196549“…Case description A medically stable male patient, 63 years old, hypertensive, but not diabetic, had entered coronary artery bypass grafting (CABG) 8 weeks before attending the outpatient cardiac rehabilitation unit and was referred for a cardiac rehabilitation program at this time. …”
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196550por Nunta, Rojarej, Khemacheewakul, Julaluk, Sommanee, Sumeth, Mahakuntha, Chatchadaporn, Chompoo, Mayuree, Phimolsiripol, Yuthana, Jantanasakulwong, Kittisak, Kumar, Anbarasu, Leksawasdi, Noppol“…The aim of the present study was to maximize the extraction of gymnemic acid (GA) from Phak Chiang Da (PCD) leaves, an indigenous medicinal plant used for diabetic treatment in Northern Thailand. The goal was to overcome the low concentration of GA in the leaves, which limits its applications among a larger population and develop a process to produce GA-enriched PCD extract powder. …”
Publicado 2023
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196551“…These articles featured AI technologies applied to diabetic retinopathy screening, ophthalmologic education, fungal keratitis detection and paediatric cataract diagnosis. …”
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196552Discovery of Aptamers and the Acceleration of the Development of Targeting Research in Ophthalmology“…The first approved aptamer drug (pegaptanib) has been used to inhibit angiogenesis in age-related macular degeneration (AMD) and diabetic retinopathy (DR), and its efficacy and safety have been demonstrated in clinical trials. …”
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196553“…After the induction period, two treatments were performed: the first with 100 mg/kg BER and the second with 10 mg/kg BER-NPs. Liver, kidney, and diabetic profiles were estimated by using standardized methods. …”
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196554por Taheri, Alemeh, Mobaser, Samira Ezzati, Golpour, Pegah, Nourbakhsh, Mona, Tavakoli-Yaraki, Masoumeh, Yarahmadi, Sahar, Nourbakhsh, Mitra“…Hesperetin, a flavonoid compound, has shown promising anti-inflammatory, anti-obesity and anti-diabetic properties. Therefore, we investigated the anti-fibrotic effects of hesperetin, through targeting ECM components and matrix metalloproteinase enzymes. …”
Publicado 2023
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196555“…BACKGROUND: Polycystic ovarian syndrome (PCOS) is a multifactorial condition with metabolic-related complications, such as diabetic nephropathy and chronic renal disorder, which are the leading cause of renal transplant globally. …”
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196556por Quansah, Elsie, Shaik, Tanveer Ahmed, Çevik, Ecehan, Wang, Xinyue, Höppener, Christiane, Meyer-Zedler, Tobias, Deckert, Volker, Schmitt, Michael, Popp, Jürgen, Krafft, Christoph“…Advanced glycation end products (AGEs) form extracellular crosslinking with collagenous proteins, which contributes to the development of diabetic complications. In this study, AGEs-related pentosidine (PENT) crosslinks-induced structural and biochemical changes are studied using multimodal multiphoton imaging, Raman spectroscopy and atomic force microscopy (AFM). …”
Publicado 2023
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196557“…A formulation containing l-methylfolate and methylcobalamin has been shown to reduce homocysteine and increase perfusion in diabetic retinopathy. This supports homocysteine intervention for CNS ischemia. …”
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196558por Xu, Ying, Phu, Jack, Aung, Htein Linn, Hesam-Shariati, Negin, Keay, Lisa, Tully, Phillip J., Booth, Andrew, Anderson, Craig S., Anstey, Kaarin J., Peters, Ruth“…OBJECTIVE: We aim to quantify the co-existence of age-related macular degeneration (AMD), glaucoma, or diabetic retinopathy (DR) and cognitive impairment or dementia. …”
Publicado 2023
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196559por MacLaren, Robert E., Fischer, M. Dominik, Gow, James A., Lam, Byron L., Sankila, Eeva-Marja K., Girach, Aniz, Panda, Sushil, Yoon, Dan, Zhao, Guolin, Pennesi, Mark E.“…In the primary endpoint analysis, three of 65 participants (5%) in the high-dose group, one of 34 (3%) participants in the low-dose group and zero of 62 (0%) participants in the control group had ≥15-letter Early Treatment Diabetic Retinopathy Study (ETDRS) improvement from baseline BCVA at 12 months (high dose, P = 0.245 versus control; low dose, P = 0.354 versus control). …”
Publicado 2023
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196560por Khoramnia, Ramin, Peto, Tunde, Koch, Frank, Taylor, Simon R, Castro de Sousa, João Paulo, Hill, Lauren, Bailey, Clare, Chakravarthy, Usha“…RESULTS: Six hundred and ninety-five eyes from 556 patients, with a mean±SD follow-up of 1150.5±357.36 days, were treated with a FAc implant. 96.7% of eyes had chronic diabetic macular oedema (cDMO). IOP lowering was achieved in 34.5% of eyes using topical agents and 4.3% by surgery. …”
Publicado 2023
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