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196561por Li, Xiaoya, Liu, Zhilong, He, Zhixiu, Wang, Xiaocheng, Li, Rongshan, Wang, Junwei, Ma, Guiqiao, Zhang, Peipei, Ma, Chanjuan“…BACKGROUND: Podocyte apoptosis is one of the important pathological mechanisms of diabetic kidney disease (DKD). Acteoside (Act), a major active component of Rehmannia glutinosa leaves total glycoside, has a strong renoprotective action. …”
Publicado 2023
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196562por Ahmad, Tessnim R, Situ, Winnie A, Chan, Nicholas T, Keenan, Jeremy D, Stewart, Jay M“…BACKGROUND: Prior studies have validated ultra-widefield imaging as a remote screening tool for diabetic retinopathy. The aim of this study was to determine its use in screening for any fundus pathology in a routine patient population. …”
Publicado 2023
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196563por Kim, Jina, Kim, Eun Joo, Ko, Hye-Jeong, Lee, Yeon-Hee, Hong, Soon-Kwang, Shin, Miyoung, Lee, Je Hyeon, Kwak, Woori“…NA4/NA6, an intermediate degradation product of β-agarase, is a high value-added product with anticancer, anti-obesity, and anti-diabetic effects. Therefore, a method that enables the efficient production of NA4/NA6 would be useful from economic and medical perspectives. …”
Publicado 2023
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196564“…PATIENTS AND METHODS: The study included 90 healthy subjects and 39 subjects with various abnormalities (29 with diabetic retinopathy, 5 with age-related macular degeneration, and 5 with choroid neovascularization). …”
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196565por Souza-Lima, Josivaldo, Matsudo, Sandra Mahecha, Valdivia-Moral, Pedro, Pérez, Waldo, Drenowatz, Clemens, Zenteno, Jorge Sapunar, Ferrari, Gerson“…Body mass index, metabolic syndrome (blood pressure, triglycerides, fasting glucose or treatment for diabetics, waist circumference, and HDL cholesterol), risk of cardiovascular disease (history and measured variables, using the Framingham risk score), tobacco use, and physical activity were measured. …”
Publicado 2023
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196566por Beijk, Marcel A.M., Klomp, Margo, Verouden, Niels J.W., van Geloven, Nan, Koch, Karel T., Henriques, José P.S., Baan, Jan, Vis, Marije M., Scheunhage, Esther, Piek, Jan J., Tijssen, Jan G.P., de Winter, Robbert J.“…Lesions were considered high risk of restenosis if one of the following applied: chronic total occlusion, lesion length >23 mm, vessel diameter <2.8 mm, or any lesion in a diabetic patient. At 1-year, the rate of the primary end point, target vessel failure (TVF), was 17.3% in the Genous stent group when compared with 10.5% in the Taxus stent group [risk difference (RD) 6.8%, 95% CI −3.1 to 16.7%], a difference predominantly due to a higher incidence of repeat revascularization in patients treated with the Genous stent. …”
Publicado 2010
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196567por Singh, Ajay K, Farag, Youssef MK, Mittal, Bharati V, Subramanian, Kuyilan Karai, Reddy, Sai Ram Keithi, Acharya, Vidya N, Almeida, Alan F, Channakeshavamurthy, Anil, Ballal, H Sudarshan, P, Gaccione, Issacs, Rajan, Jasuja, Sanjiv, Kirpalani, Ashok L, Kher, Vijay, Modi, Gopesh K, Nainan, Georgy, Prakash, Jai, Rana, Devinder Singh, Sreedhara, Rajanna, Sinha, Dilip Kumar, V, Shah Bharat, Sunder, Sham, Sharma, Raj K, Seetharam, Sridevi, Raju, Tatapudi Ravi, Rajapurkar, Mohan M“…It should be stressed to all primary care physicians taking care of hypertensive and diabetic patients to screen for early kidney damage. …”
Publicado 2013
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196568por Burke, Thomas F, Hines, Rosemary, Ahn, Roy, Walters, Michelle, Young, David, Anderson, Rachel Eleanor, Tom, Sabrina M, Clark, Rachel, Obita, Walter, Nelson, Brett D“…Only 20% of lower level facilities had glucometers, and only 33% of higher level facilities could care for diabetic emergencies. No facilities had sepsis clinical guidelines. …”
Publicado 2014
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196569por Marics, Gábor, Lendvai, Zsófia, Lódi, Csaba, Koncz, Levente, Zakariás, Dávid, Schuster, György, Mikos, Borbála, Hermann, Csaba, Szabó, Attila J, Tóth-Heyn, Péter“…BACKGROUND: Continuous Glucose Monitoring (CGM) has become an increasingly investigated tool, especially with regards to monitoring of diabetic and critical care patients. The continuous glucose data allows the calculation of several glucose variability parameters, however, without specific application the interpretation of the results is time-consuming, utilizing extreme efforts. …”
Publicado 2015
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196570por Sanderson, Christine, Quinn, Stephen J, Agar, Meera, Chye, Richard, Clark, Katherine, Doogue, Matthew, Fazekas, Belinda, Lee, Jessica, Lovell, Melanie R, Rowett, Debra, Spruyt, Odette, Currow, David C“…Most of the evidence however relates to non-malignant, chronic pain syndromes (diabetic neuropathy, postherpetic neuralgia, central pain syndromes, fibromyalgia). …”
Publicado 2015
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196571por Morelli, E, Leone, E, Cantafio, M E Gallo, Di Martino, M T, Amodio, N, Biamonte, L, Gullà, A, Foresta, U, Pitari, M R, Botta, C, Rossi, M, Neri, A, Munshi, N C, Anderson, K C, Tagliaferri, P, Tassone, P“…Finally, in vivo intra-tumor or systemic delivery of formulated miR-125b-5p mimics against human MM xenografts in severe combined immunodeficient/non-obese diabetic mice induced significant anti-tumor activity and prolonged survival. …”
Publicado 2015
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196572por Li, Ya, Shi, Hao, Wang, Wei-Ming, Peng, Ai, Jiang, Geng-Ru, Zhang, Jin-Yuan, Ni, Zhao-Hui, He, Li-Qun, Niu, Jian-Ying, Wang, Nian-Song, Mei, Chang-Lin, Xu, Xu-Dong, Guo, Zhi-Yong, Yuan, Wei-Jie, Yan, Hai-Dong, Deng, Yue-Yi, Yu, Chen, Cen, Jun, Zhang, Yun, Chen, Nan“…Anemia was more prevalent in patients with diabetic nephropathy (68.0%) than in patients with hypertensive renal damage (56.6%) or chronic glomerulonephritis (46.1%, both P < 0.001). …”
Publicado 2016
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196573por Morrison, M C, Mulder, P, Salic, K, Verheij, J, Liang, W, van Duyvenvoorde, W, Menke, A, Kooistra, T, Kleemann, R, Wielinga, P Y“…SUBJECTS/METHODS: To investigate effects of caspase-1 inhibition under therapeutic conditions, male LDLR−/−.Leiden mice were fed a high-fat diet (HFD) for 9 weeks to induce a pre-diabetic state before start of treatment. Mice were then continued on HFD for another 12 weeks, without (HFD) or with (HFD-YVAD) treatment with the caspase-1 inhibitor Ac-YVAD-cmk (40 mg kg(−1) per day). …”
Publicado 2016
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196574por Wecker, Thomas, Ehlken, Christoph, Bühler, Anima, Lange, Clemens, Agostini, Hansjürgen, Böhringer, Daniel, Stahl, Andreas“…METHODS: Five-year analysis of real-life VA developments and injection patterns from 2072 patients (2577 eyes; 33 187 injections) with chronically active disease undergoing pro-re-nata treatment for age-related macular degeneration (AMD), diabetic macular oedema (DME), retinal vein occlusion (RVO) and myopic choroidal neovascularisation (CNV). …”
Publicado 2017
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196575por Krishnan, Sridevi, Shimoda, Michiko, Sacchi, Romina, Kailemia, Muchena J., Luxardi, Guillaume, Kaysen, George A., Parikh, Atul N., Ngassam, Viviane N., Johansen, Kirsten, Chertow, Glenn M., Grimes, Barbara, Smilowitz, Jennifer T., Maverakis, Emanual, Lebrilla, Carlito B., Zivkovic, Angela M.“…HDL were purified from healthy controls (n = 13), subjects with metabolic syndrome (MetS) (n = 13), and diabetic hemodialysis (HD) patients (n = 24). Concentrations of HDL-bound serum amyloid A (SAA), lipopolysaccharide binding protein (LBP), apolipoprotein A-I (ApoA-I), apolipoprotein C-III (ApoC-III), α-1-antitrypsin (A1AT), and α-2-HS-glycoprotein (A2HSG); and the site-specific glycovariations of ApoC-III, A1AT, and A2HSG were measured. …”
Publicado 2017
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196576por Gomes, Walter J., Moreira, Rita Simone, Zilli, Alexandre Cabral, Bettiati Jr, Luiz Carlos, Figueira, Fernando Augusto Marinho dos Santos, D'Azevedo, Stephanie Steremberg Pires, Soares, Marcelo José Ferreira, Fernandes, Marcio Pimentel, Ardito, Roberto Vito, Bogdan, Renata Andrea Barberio, Campagnucci, Valquíria Pelisser, Nakasako, Diana, Kalil, Renato Abdala Karam, Rodrigues, Clarissa Garcia, Rodrigues Junior, Anilton Bezerra, Cascudo, Marcelo Matos, Atik, Fernando Antibas, Lima, Elson Borges, Nina, Vinicius José da Silva, Heluy, Renato Albuquerque, Azeredo, Lisandro Gonçalves, Henrique Junior, Odilon Silva, de Mendonça, José Teles, Silva, Katharina Kelly de Oliveira Gama, Pandolfo, Marcelo, de Lima Júnior, José Dantas, Faria, Renato Max, dos Santos, Jonas Pereira, Paez, Rodrigo Pereira, Coelho, Guilherme Henrique Biachi, Pereira, Sergio Nunes, Senger, Roberta, Buffolo, Enio, Caputi, Guido Marco, Santo, José Amalth do Espírito, de Oliveira, Juliana Aparecida Borges, Berwanger, Otavio, Cavalcanti, Alexandre Biasi, Jatene, Fabio B.“…Male patients comprised 66%, 30% were diabetics, 46% had dyslipidemia, 28% previously sustained a myocardial infarction, and 9.4% underwent prior cardiovascular surgery. …”
Publicado 2017
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196577por Cui, J, Sun, D, Lu, H, Dai, R, Xing, L, Dong, H, Wang, L, Wei, D, Jiang, B, Jiao, Y, Jablonski, M M, Charles, S, Gu, W, Chen, H“…Main outcomes and measures include best-corrected visual acuity (BCVA), using Early Treatment Diabetic Retinopathy Study (ETDRS); number of injections; central retinal thickness (CRT); and leakage of choroidal neovascularization before and after the treatment was analyzed by fluorescein fundus angiography and indocyanine green angiography. …”
Publicado 2018
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196578por Huang, Yujie, Sun, Yifei, Cao, Yizhi, Sun, Hui, Li, Min, You, Hui, Su, Dongming, Li, Yanjiao, Liang, Xiubin“…HRD1 expression was also lower in kidney tissues from mice with diabetic nephropathy (DN) than in control mice. Forced expression of HRD1 also inhibited apoptosis in HKC-8 cells, while HRD1 overexpression decreased the expression of phosphorylated eIF2α and eIF2α. …”
Publicado 2017
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196579por Wang, Minan, Yao, Li-Chin, Cheng, Mingshan, Cai, Danying, Martinek, Jan, Pan, Chong-Xian, Shi, Wei, Ma, Ai-Hong, De Vere White, Ralph W., Airhart, Susan, Liu, Edison T., Banchereau, Jacques, Brehm, Michael A., Greiner, Dale L., Shultz, Leonard D., Palucka, Karolina, Keck, James G.“…To this end, nonobese diabetic (NOD).Cg-Prkdc(scid)IL2rg(tm1Wjl)/Sz (null; NSG) mice were transplanted with human (h)CD34(+) hematopoietic progenitor and stem cells, which leads to the development of human hematopoietic and immune systems [humanized NSG (HuNSG)]. …”
Publicado 2018
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196580por Bourne, Rupert R A, Jonas, Jost B, Bron, Alain M, Cicinelli, Maria Vittoria, Das, Aditi, Flaxman, Seth R, Friedman, David S, Keeffe, Jill E, Kempen, John H, Leasher, Janet, Limburg, Hans, Naidoo, Kovin, Pesudovs, Konrad, Peto, Tunde, Saadine, Jinan, Silvester, Alexander J, Tahhan, Nina, Taylor, Hugh R, Varma, Rohit, Wong, Tien Y, Resnikoff, Serge“…In 2015, cataract was the most common cause for blindness, followed by age-related macular degeneration (AMD), glaucoma, uncorrected refractive error, diabetic retinopathy and cornea-related disorders, with declining burden from cataract and AMD over time. …”
Publicado 2018
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